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Author : Clevio Nobrega
Publisher :
ISBN 13 : 9783319127675
Total Pages : 208 pages
Book Rating : 4.1/5 (276 download)
Download or read book Molecular Mechanisms Underpinning the Development of Obesity written by Clevio Nobrega and published by . This book was released on 2014-12-31 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Clévio Nóbrega
Publisher : Springer
ISBN 13 : 3319127667
Total Pages : 200 pages
Book Rating : 4.3/5 (191 download)
Download or read book Molecular Mechanisms Underpinning the Development of Obesity written by Clévio Nóbrega and published by Springer. This book was released on 2014-12-12 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a multi-factorial disease, in which an excess of accumulated body fat can reach levels capable of affecting health. It results from an interplay between environmental factors, eating behavior, genes, epigenetics, and neuronal stimuli. The main aim of this book is to provide a state-of-the-art revision about the molecular mechanisms underpinning the development of obesity, reviewing the current knowledge in areas like monogenic and polygenic obesity forms, but also providing an updated view of the emerging knowledge about epigenetics, nutrigenomics, and neuronal aspects that also contribute to obesity.
Author : Dimiter Avtanski
Publisher : Springer Nature
ISBN 13 : 3031397215
Total Pages : 236 pages
Book Rating : 4.0/5 (313 download)
Download or read book Obesity, Diabetes and Inflammation written by Dimiter Avtanski and published by Springer Nature. This book was released on 2023-09-26 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a worldwide epidemic that affects half a billion people. It has been estimated that, if current trends continue, by 2050, 60% of men and 50% of women worldwide will be obese. Hypertrophy and hyperplasia of white adipose tissue caused by overweight and obesity lead to a chronic inflammatory state, which results in impaired insulin sensitivity and the development of diabetes. Currently, the number of people affected by diabetes globally exceeds 400 million (rising more rapidly in low- and middle-income countries). In 2019, diabetes was the ninth leading cause of mortality, with an estimated 1.5 million direct deaths. This book provides a comprehensive overview of the relationship between inflammation, obesity, and diabetes. It focuses on the pathogenesis and biological mechanisms of obesity, the interaction between adipose tissue and the immune system, the role of genetic and environmental factors, the progression of cardiovascular complications, and the association of obesity and inflammation with type 1 and type 2 diabetes, as well as gestational diabetes. This volume also includes practical recommendations for preventing and managing these conditions using both lifestyle modifications and pharmacological interventions. Written by experts in the field, Obesity, Diabetes and Inflammation: Molecular Mechanisms and Clinical Management addresses the role of inflammation in both obesity and diabetes, its effect on vascular and non-vascular pathologies, oxidative stress, genetics, and epigenetics. This text aims to be a valuable resource for researchers, clinicians, and students of medicine at all levels.
Author : Paramjit S. Tappia
Publisher : Springer Nature
ISBN 13 : 3030847632
Total Pages : 420 pages
Book Rating : 4.0/5 (38 download)
Download or read book Cellular and Biochemical Mechanisms of Obesity written by Paramjit S. Tappia and published by Springer Nature. This book was released on 2021-12-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global health has been challenged with the dawning of the era of the obesity epidemic, and thus as a consequence, strategies to reduce obesity have become public health priorities. According to the United Nations, obesity has been identified as a concern for achieving Sustainable Development Goals. Obesity is a serious health problem with an increased risk of several common diseases including diabetes, cardiovascular disease, and cancer. Although the fundamental cause of obesity and overweight is an imbalance between calorie intake and calorie expenditure, the underlying biochemical and metabolic processes that cause obesity are not fully understood. Two earlier volumes dedicated to the subject of obesity, published in the series “Advances in Biochemistry in Health and Disease” focused on the pathophysiology of obesity-induced health complications and the biochemistry of cardiovascular dysfunction in obesity. This book brings together contributions from international experts in the field to describe advancements on the mechanisms leading to development of obesity and related complications. There are 21 chapters in two different parts in this book, comprising of Part I: Pathophysiologic Mechanisms of Obesity (11 chapters) and Part II: Therapeutic Mechanisms of Obesity (10 chapters). This book will serve as a resource and be of interest to health professionals, medical students, fellows, residents and graduate students. It will also evoke innovative research and effective approaches for the prevention of obesity. This volume will accentuate that obesity is a major health hazard in its own right and that appropriate public health measures should be implemented to prevent or reduce or even reverse the impact of this global chronic disease.
Author : International Conference on the Adipocyte and Obesity. 1982, Toronto
Publisher :
ISBN 13 : 9780608006222
Total Pages : 327 pages
Book Rating : 4.0/5 (62 download)
Download or read book The Adipocyte and Obesity written by International Conference on the Adipocyte and Obesity. 1982, Toronto and published by . This book was released on 1983-01-01 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Juergen Eckel
Publisher : Springer Nature
ISBN 13 : 3030999955
Total Pages : 508 pages
Book Rating : 4.0/5 (39 download)
Download or read book From Obesity to Diabetes written by Juergen Eckel and published by Springer Nature. This book was released on 2022-07-21 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of patients with diabetes has been continuously rising with more than 450 Mio. people suffering from this disease at the present time. Substantial progress has been made in understanding the molecular pathways leading from excessive fat accumulation to metabolic perturbation and finally diabetes manifestation. This edition of the "Handbook of Experimental Pharmacology" aims to analyze new insight into the pathophysiology of obesity, to decipher the complex links to diabetes and its complications, and to collect most recent information on new strategies for prevention and treatment of obesity and diabetes.
Author : Shamim I. Ahmad
Publisher : Springer
ISBN 13 : 3319198211
Total Pages : 362 pages
Book Rating : 4.3/5 (191 download)
Download or read book Obesity written by Shamim I. Ahmad and published by Springer. This book was released on 2015-10-19 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings a comprehensive treatise about obesity, examining the measures that can be taken to stop and even reduce obesity if these right measures are taken in time. Recent studies show that obesity is on the increase at an alarming rate, especially in the industrialized and affluent countries. A number of reasons have been put forward for this increase, including life style choices, over-eating, over-use of commercially processed food, addiction for fast food, high caloric diet specially containing high levels of sugar and fat, lack of exercise and sedentary life style. Also genetic make up has been associated with obesity. Obesity can lead to a variety of lethal diseases, notably coronary heart disease, cancer and diabetes. These diseases account for the highest number of human death amongst all other causes. There are also a number of other side effects associated with obesity including increased stress, loss of intelligentsia, pancreatitis, premature birth and osteoarthritis. In recent years media have been playing important roles in highlighting the lethality and damage caused by obesity, nevertheless no significant effects can be seen in the population and obesity remains on the increase, especially amongst children. The editors believe that it is important that more education, campaign and research are used to stop this increasing disease.
Author : Shamim I. Ahmad
Publisher : CRC Press
ISBN 13 : 0429811772
Total Pages : 480 pages
Book Rating : 4.4/5 (298 download)
Download or read book Handbook of Mitochondrial Dysfunction written by Shamim I. Ahmad and published by CRC Press. This book was released on 2019-05-15 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria produce the chemical energy necessary for eukaryotic cell functions; hence mitochondria are an essential component of health, playing roles in both disease and aging. More than 80 human diseases and syndromes are associated with mitochondrial dysfunction; this book focuses upon diseases linked to these ubiquitous organelles. Accumulation of mitochondrial DNA damage results in mitochondrial dysfunction through two main pathways. Mutation in mitochondrial DNA causes diseases such as Kearns-Sayre syndrome and Pearson syndrome. Mutation in chromosomal DNA causes diseases such as Parkinson's disease and schizophrenia. These and many other diseases are reviewed in this book. Key Features Presents the detailed structure of mitochondria, mitochondrial function, roles of oxidants and antioxidants in mitochondrial dysfunction. Includes summary of both causes and effects of these diseases. Discusses current and potential future therapies for mitochondrial dysfunction diseases Explores a wide variety of diseases caused by dysfunctional mitochondria.
Author : Lotte Meinert
Publisher : Berghahn Books
ISBN 13 : 1800733054
Total Pages : 274 pages
Book Rating : 4.8/5 (7 download)
Download or read book Configuring Contagion written by Lotte Meinert and published by Berghahn Books. This book was released on 2022-02-11 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding our understanding of contagion beyond the typical notions of infection and pandemics, this book widens the field to include the concept of biosocial epidemics. The chapters propose varied and detailed answers to questions about epidemics and their contagious potential for specific infections and non-infectious conditions. Together they explore how inseparable social and biological processes configure co-existing influences, which create epidemics, and in doing so stress the role of social inequality in these processes. The authors compellingly show that epidemics do not spread evenly in populations or through simple coincidental biological contagion: they are biosocially structured and selective, and happen under specific economic, political and environmental conditions. This volume illustrates that an understanding of biosocial factors is vital for ensuring effective strategies for the containment of epidemics.
Author : Katy Tapper
Publisher : Bloomsbury Publishing
ISBN 13 : 1137579498
Total Pages : 443 pages
Book Rating : 4.1/5 (375 download)
Download or read book Health Psychology and Behaviour Change written by Katy Tapper and published by Bloomsbury Publishing. This book was released on 2021-02-27 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook offers a fresh approach to health psychology through the theory and practice of behaviour change. Using an array of case studies from around the world, it discusses how we can develop and evaluate behaviour change interventions. The book encourages active engagement with contemporary discussions about health behaviours, covering areas of emerging importance such as weight stigma, vaping, nudges, vaccine hesitancy and paleo-inspired lifestyles. With a focus upon critical thinking, this book will equip students for success in their research projects and beyond. Ideal for students of Health Behaviour Change and Health Psychology, this textbook is also relevant to those taking courses in related fields such as Nursing and Public Health.
Author : Andrew J. Dannenberg
Publisher : Springer Science & Business Media
ISBN 13 : 1461468191
Total Pages : 440 pages
Book Rating : 4.4/5 (614 download)
Download or read book Obesity, Inflammation and Cancer written by Andrew J. Dannenberg and published by Springer Science & Business Media. This book was released on 2013-05-21 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: In addition to its metabolic and endocrinologic effects, obesity and adipose tissue have now been shown to be associated with low grade inflammation resulting in cellular and humoral inflammatory factors of which the latter may act by endocrine, paracrine and autocrine mechanisms. These inflammatory mediators have increasingly been suggested as contributing to the obesity link to carcinogenesis and cancer promotion. This volume of Energy Balance and Cancer will focus on recent developments and cutting edge research pointing to inflammation and inflammatory factors as key mediators of this linkage. The volume first provides information on inflammation as an important link between obesity and insulin resistance, which is in itself linked to promotion of cancer through hyperinsulinemia. The volume then covers some of the most important mechanisms by which obesity leads to inflammation, including the novel inflammasome concept, alterations in chromatin structure, circulating inflammatory factors, unique cellular interactions between adipocytes and macrophages and the direct link of dietary fat to inflammation and cancer. Overall, this volume will provide important insight to help understand how inflammation may help modulate the linkage between obesity and cancer and serve as a platform for developing future research in this area.
Author : HK Chopra
Publisher : Jaypee Brothers Medical Publishers
ISBN 13 : 9354653936
Total Pages : 981 pages
Book Rating : 4.3/5 (546 download)
Download or read book Advances in Statin Therapy & Beyond in CVD (ASTC) written by HK Chopra and published by Jaypee Brothers Medical Publishers. This book was released on 2022-03-30 with total page 981 pages. Available in PDF, EPUB and Kindle. Book excerpt: CVD, or cardiovascular disease, is a general term that describes a disease of the heart or blood vessels. It is one of the most common causes of death. Statins are a group of medicines that can help lower the level of low-density lipoprotein (LDL) cholesterol in the blood. LDL cholesterol of often referred to as ‘bad cholesterol’, and statins reduce its production in the liver. Having a high level of LDL is potentially dangerous as it can lead to hardening and narrowing of the arteries (NHS). Comprising nearly 1000 pages, this book is a comprehensive guide to the latest advances in statin therapy and its clinical application for cardiovascular disease. Divided into 29 sections, the text begins with clinical aspects of CVD, dyslipidemia (the imbalance of lipids such as cholesterol), and the use of statins for treatment. The next sections provide detailed discussion on the use of statins for different types of CVD, including coronary artery disease, hypertension, heart failure, arrhythmia, stroke, and more. The following chapters cover statin use for other systemic diseases such as obesity, kidney disease, diabetes, ocular disorders, skin conditions and many more. The book concludes with an insight into future therapies, with emphasis on PCSK9 inhibitors, a new treatment for lowering cholesterol in the blood.
Author : Jolanta Weaver
Publisher : Elsevier Health Sciences
ISBN 13 : 0323496008
Total Pages : 350 pages
Book Rating : 4.3/5 (234 download)
Download or read book Practical Guide to Obesity Medicine written by Jolanta Weaver and published by Elsevier Health Sciences. This book was released on 2017-09-29 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get a quick, expert overview of the many key facets of obesity management with this concise, practical resource by Dr. Jolanta Weaver. Ideal for any health care professional who cares for patients with a weight problem. This easy-to-read reference addresses a wide range of topics – including advice on how to "unpack" the behavioral causes of obesity in order to facilitate change, manage effective communication with patients suffering with weight problems and future directions in obesity medicine. Features a wealth of information on obesity, including hormones and weight problems, co-morbidities in obesity, genetics and the onset of obesity, behavioral aspects and psychosocial approaches to obesity management, energy and metabolism management, and more. Discusses pharmacotherapies and surgical approaches to obesity. Consolidates today’s available information and guidance in this timely area into one convenient resource.
Author : Jose M Saavedra
Publisher : Woodhead Publishing
ISBN 13 : 0128244054
Total Pages : 654 pages
Book Rating : 4.1/5 (282 download)
Download or read book Early Nutrition and Long-Term Health written by Jose M Saavedra and published by Woodhead Publishing. This book was released on 2022-08-06 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early Nutrition and Long-Term Health: Mechanisms, Consequences, and Opportunities, Second Edition updates and expands upon the content in the first edition and adds focus on actionable and modifiable aspects of nutrition that have an impact on long-term health and disease. Part I examines the associations and the mechanisms of early life nutrition on growth as well as the development of cognitive, metabolic, immune, and dietary patterns and behaviors. Part II reviews the associations and impact of early life nutrition on non-communicable disease as well as their societal and economic impact. Part III focuses on the dietary and nutritional needs and approaches to optimizing the different stages of nutrition, from conception to the second year of life. Nutritionists, pediatricians, academics with research interest in this area, and food industry and healthcare professionals working in infant/child product and services, as well as students studying related disciplines, will benefit from this updated reference. Examines the relation between early life nutrition and long-term health Reviews the mechanistic aspects of the impact of diet, nutrition, from conception through the first years of life, on health in later life Details the associations and the impact of early life nutrition on growth and development, cognition, immunity, metabolism, and dietary habits and patterns Addresses the relationship of early life nutrition and with non-communicable diseases, including allergies, cardiovascular diseases, metabolic conditions, and obesity, as well as approaches to curtail them Explores the current societal and economic impact and the potential for interventions to improving nutrition and health
Author : Trygve Tollefsbol
Publisher : Academic Press
ISBN 13 : 0128032405
Total Pages : 944 pages
Book Rating : 4.1/5 (28 download)
Download or read book Medical Epigenetics written by Trygve Tollefsbol and published by Academic Press. This book was released on 2016-06-21 with total page 944 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Epigenetics provides a comprehensive analysis of the importance of epigenetics to health management. The purpose of this book is to fill a current need for a comprehensive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic diseases that affect these systems and modes of treating epigenetic-based disorders and diseases. The intent of this book is to provide a stand-alone comprehensive volume that will cover all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. The overall goal is to provide the leading book on medical epigenetics that will be useful not only to physicians, nurses, medical students and many others directly involved with health care, but also investigators in life sciences, biotech companies, graduate students and many others who are interested in more applied aspects of epigenetics. Research in the area of translational epigenetics is a cornerstone of this volume. Critical reviews dedicated to the burgeoning role of epigenetics in medical practice Coverage of emerging topics including twin epigenetics as well as epigenetics of gastrointestinal disease, muscle disorders, endocrine disorders, ocular medicine, pediatric diseases, sports medicine, noncoding RNA therapeutics, pain management and regenerative medicine Encompasses a disease-oriented perspective of medical epigenetics as well as diagnostic and prognostic epigenetic approaches to applied medicine
Author : J-L Sebedio
Publisher : Elsevier
ISBN 13 : 1782420924
Total Pages : 269 pages
Book Rating : 4.7/5 (824 download)
Download or read book Metabolomics as a Tool in Nutrition Research written by J-L Sebedio and published by Elsevier. This book was released on 2014-11-28 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics is a multidisciplinary science used to understand the ways in which nutrients from food are used in the body and how this can be optimised and targeted at specific nutritional needs. Metabolomics as a Tool in Nutrition Research provides a review of the uses of metabolomics in nutritional research. Chapters cover the most important aspects of the topic such as analysis techniques, bioinformatics and integration with other ‘omic’ sciences such as proteomics and genomics. The final chapters look at the impact of exercise on metabolomic profiles and future trends in metabolomics for nutrition research.
Author : Valdur Saks
Publisher : John Wiley & Sons
ISBN 13 : 3527621105
Total Pages : 633 pages
Book Rating : 4.5/5 (276 download)
Download or read book Molecular System Bioenergetics written by Valdur Saks and published by John Wiley & Sons. This book was released on 2008-01-08 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this first integrated view, practically each of the world's leading experts has contributed to this one and only authoritative resource on the topic. Bringing systems biology to cellular energetics, they address in detail such novel concepts as metabolite channeling and medical aspects of metabolic syndrome and cancer.
