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Molecular Mechanisms Of Memory And Synaptic Plasticity
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Book Synopsis Neural Plasticity and Memory by : Federico Bermudez-Rattoni
Download or read book Neural Plasticity and Memory written by Federico Bermudez-Rattoni and published by CRC Press. This book was released on 2007-04-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
Book Synopsis Molecular Mechanisms of Memory and Synaptic Plasticity by : Karsten Baumgaertel
Download or read book Molecular Mechanisms of Memory and Synaptic Plasticity written by Karsten Baumgaertel and published by . This book was released on 2007 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mechanisms of Memory by : J. David Sweatt
Download or read book Mechanisms of Memory written by J. David Sweatt and published by Academic Press. This book was released on 2009-09-28 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully revised second edition provides the only unified synthesis of available information concerning the mechanisms of higher-order memory formation. It spans the range from learning theory, to human and animal behavioral learning models, to cellular physiology and biochemistry. It is unique in its incorporation of chapters on memory disorders, tying in these clinically important syndromes with the basic science of synaptic plasticity and memory mechanisms. It also covers cutting-edge approaches such as the use of genetically engineered animals in studies of memory and memory diseases. Written in an engaging and easily readable style and extensively illustrated with many new, full-color figures to help explain key concepts, this book demystifies the complexities of memory and deepens the reader's understanding. - More than 25% new content, particularly expanding the scope to include new findings in translational research. - Unique in its depth of coverage of molecular and cellular mechanisms - Extensive cross-referencing to Comprehensive Learning and Memory - Discusses clinically relevant memory disorders in the context of modern molecular research and includes numerous practical examples
Book Synopsis Molecular Mechanisms Underlying Long Term Memory and Synaptic Plasticity by :
Download or read book Molecular Mechanisms Underlying Long Term Memory and Synaptic Plasticity written by and published by . This book was released on 2018 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Molecular Mechanisms of Synaptic Plasticity Impairments in Alzheimer's Disease by : Gong-Ping Liu
Download or read book The Molecular Mechanisms of Synaptic Plasticity Impairments in Alzheimer's Disease written by Gong-Ping Liu and published by Frontiers Media SA. This book was released on 2022-02-16 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cellular and Molecular Mechanisms of Synaptic Plasticity at Hippocampal and Cortical Synapses by : Roberto De Pasquale
Download or read book Cellular and Molecular Mechanisms of Synaptic Plasticity at Hippocampal and Cortical Synapses written by Roberto De Pasquale and published by Frontiers Media SA. This book was released on 2022-08-11 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neuronal Mechanisms of Memory Formation by : Christian Hölscher
Download or read book Neuronal Mechanisms of Memory Formation written by Christian Hölscher and published by Cambridge University Press. This book was released on 2001 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Long-term potentiation (LTP) is by far the most dominant model for neuronal changes that might encode memory. LTP is an elegant concept that meets many criteria set up by theoreticians long before the model's discovery, and it also fits anatomical data of learning-dependent synapse changes. Since the discovery of LTP, the question has remained about how closely LTP produced in vitro by artificial stimulation of neurons actually models putative learning-induced synaptic changes. A number of recent investigations have tried to correlate synaptic changes observed after learning with changes produced by artificial stimulation of neurons. These studies have failed to find a correlation between the two forms of synaptic plasticity. In this book, an international group of neurobiologists and psychologists discuss their latest ideas and data. The results of experiments using electrophysiological techniques in vitro are discussed and compared with the results of in vivo experiments. Learning experiments are also discussed. Theoretical models such as the Hebb theory of synaptic changes during learning are compared to different models that do not predict upregulation of synaptic transmission. A wide approach is taken, and research and models in different brain areas such as the neocortex and the basal brain are discussed.
Download or read book Molecular Basis of Memory written by and published by Academic Press. This book was released on 2014-01-30 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special volume of Progress in Molecular Biology and Translational Science provides a current overview of how memory is processed in the brain. A broad range of topics are presented by leaders in the field, ranging from brain circuitry to synaptic plasticity to the molecular machinery that contributes to the brain's ability to maintain information across time. Memory systems in the prefrontal cortex, hippocampus and amygdala are considered as well. In addition, the volume covers recent contributions to our understanding of memory from in vivo imaging, optogenetic, electrophysiological, biochemical and molecular biological studies. - Articles from world renowned experts in memory - Covering topics from signaling, epigenetic, RNA translation to plasticity - Methodological approaches include molecular and cellular, behavioral, electrophysiological, optogenetic and functional imaging
Book Synopsis Molecular mechanisms of synaptic plasticity by :
Download or read book Molecular mechanisms of synaptic plasticity written by and published by Cuvillier Verlag. This book was released on 2002-01-01 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Discovering the Brain by : National Academy of Sciences
Download or read book Discovering the Brain written by National Academy of Sciences and published by National Academies Press. This book was released on 1992-01-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
Book Synopsis The Hippocampus Book by : Per Andersen
Download or read book The Hippocampus Book written by Per Andersen and published by Oxford University Press. This book was released on 2007 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.
Book Synopsis Mechanisms of Memory by : J. David Sweatt
Download or read book Mechanisms of Memory written by J. David Sweatt and published by Academic Press. This book was released on 2019-08 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of Memory, Third Edition, is the only available comprehensive overview of the cellular and molecular mechanisms underlying higher-order learning and memory. Focusing on mechanisms relevant to hippocampus-dependent memory formation, the book progresses systematically from behavior to cellular physiology at molecular and genetic levels. Moreover, it integrates modern discoveries concerning learning and memory disorders, from inherited disorders, to aging and psychiatric disorders. The book emphasizes results from the cutting-edge of contemporary methodologies, such as genetic engineering, molecular biology, complex behavioral characterization, cellular physiology, epigenetics and molecular structure. This updated edition has been expanded to include eight new chapters covering the role of the prefrontal cortex in short-term and working memory, recent discoveries regarding the CNS dopamine system and its implications for reward-based learning, glial cell function in memory formation, the role of altered protein synthesis in long-term memory formation, AMPA receptor trafficking and regulation, and the role of epigenetics in memory formation. This new release continues to be the standard work on all aspects of learning and memory. As such, it is essential reading for students and researchers alike. Presents a unified view of memory mechanisms, from behavior to genes Discusses clinically relevant memory disorders in the context of modern molecular research Provides numerous practical examples on how to implement a research program in the learning and memory area Offers a balanced treatment of the strengths and weaknesses inherent in modern experimental design Emphasizes hippocampus-dependent memory formation while also drawing examples from many different brain regions, types of learning, and various animal model systems
Book Synopsis Novel Mechanisms of Memory by : Karl Peter Giese
Download or read book Novel Mechanisms of Memory written by Karl Peter Giese and published by Springer. This book was released on 2015-12-09 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book integrates discoveries from recent years to show the diversity of molecular mechanisms that contribute to memory consolidation, reconsolidation, extinction, and forgetting. It provides a special focus on the processes that govern functional and structural plasticity of dendritic spines. In nine chapters, new and important ideas related to learning and memory processes will be presented. Themes discussed include the role of AMPA receptors in memory, two signalling cascades involved in local spine remodelling and memory, the role of extracellular matrix proteins in memory, the regulation of gene expression and protein translation, and mechanisms of retrieval-induced memory modulation and forgetting. We believe that the study of these topics represents a great step toward understanding the complexity of the brain and the processes it governs.
Book Synopsis Molecular mechanisms of glutamatergic synapse function and dysfunction by : Dhrubajyoti Chowdhury
Download or read book Molecular mechanisms of glutamatergic synapse function and dysfunction written by Dhrubajyoti Chowdhury and published by Frontiers Media SA. This book was released on 2022-12-22 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neurogenesis and Neural Plasticity by : Catherine Belzung
Download or read book Neurogenesis and Neural Plasticity written by Catherine Belzung and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain. With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.
Book Synopsis Molecular Mechanisms of Synaptic Plasticity by : Hongik Hwang
Download or read book Molecular Mechanisms of Synaptic Plasticity written by Hongik Hwang and published by . This book was released on 2016 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synaptic plasticity serves as a central molecular mechanism underlying learning and memory formation in the brain. An increase in intracellular calcium concentrations triggered by neuronal activity induces synaptic plasticity, and calmodulin is a key protein that detects the elevated calcium levels and propagates downstream signaling. Neurogranin is a neuron-specific protein that binds to calmodulin and regulates the availability of calmodulin in the postsynaptic compartments of excitatory neurons. Dysregulation of neurogranin has been reported to cause altered synaptic plasticity as well as impairment in hippocampus-dependent learning, and is also associated with the higher risk of developing neurodegenerative and psychiatric diseases. Therefore, it is critical to understand how neurogranin regulates the induction of synaptic plasticity in the brain at the molecular level. The focus of this thesis is to examine how the changes in neurogranin expression levels contribute to the induction of synaptic plasticity in the hippocampus with a spike-timing-dependent plasticity paradigm and to understand the underlying molecular mechanisms. Using lentivirus-mediated manipulations of neurogranin levels in hippocampal CAl neurons, we found that increasing neurogranin levels in CAI neurons prolongs the timing window for spike-timing-dependent long-term potentiation (LTP), whereas acute knockdown of neurogranin inhibits the expression of LTP via regulating PP2B activity. We have also found that neurogranin interferes with calcium-dependent inactivation of neuronal L-type calcium channels and allows a sustained influx of calcium during the membrane depolarization in hippocampal neurons. Our results indicate that dynamic changes in neurogranin levels play a crucial role in setting the threshold for inducing LTP in spike-timing-dependent plasticity in the hippocampus.
Book Synopsis Synaptic Plasticity in the Hippocampus by : Helmut L. Haas
Download or read book Synaptic Plasticity in the Hippocampus written by Helmut L. Haas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second time that I have had the honor of opening an interna tional symposium dedicated to the functions of the hippocampus here in Pecs. It was a pleasure to greet the participants in the hope that their valuable contributions will make this meeting a tradition in this town. As one of the hosts of the symposium, I had the sorrowful duty to remind you of the absence of a dear colleague, Professor Graham God dard. His tragic and untimely death represents the irreparable loss of both a friend and an excellent researcher. This symposium is dedicated to his memory. If I compare the topics of the lectures of this symposium with those of the previous one, a striking difference becomes apparent. A dominating tendency of the previous symposium was to attempt to define hippocam pal function or to offer data relevant to supporting or rejecting existing theoretical positions. No such tendency is reflected in the titles of the present symposium, in which most of the contributions deal with hip pocampal phenomena at the most elementary level. Electrical, biochemi cal, biophysical, and pharmacological events at the synaptic, membrane, or intracellular level are analyzed without raising the question of what kind of integral functions these elementary phenomena are a part of.
