Molecular Logic-based Computation

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Publisher : Royal Society of Chemistry
ISBN 13 : 1782626239
Total Pages : 417 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Molecular Logic-based Computation by : A Prasanna de Silva

Download or read book Molecular Logic-based Computation written by A Prasanna de Silva and published by Royal Society of Chemistry. This book was released on 2016-01-13 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: We all learn - in schools, factories, bars and streets. We gather, store, process and transmit information in society. Molecular systems involved in our senses and within our brains allow all this to happen and molecular systems allow living things of all kinds to handle information for the purpose of survival and growth. Nevertheless, the vital link between molecules and computation was not generally appreciated until a few decades ago. Semiconductor-based information technology had penetrated society at many levels and the interest in maintaining momentum of this revolution led to the consideration of molecules, among others, as possible information handlers. Such an overlap between the recent engineering-oriented revolution with the ancient biology-oriented success story is very interesting and George Boole's times in Ireland 150 years ago produced the logic ideas that provide the foundations of computation to this day. Molecular logic and computation is a field which is 17 years young, has had a healthy growth and is a story which deserves to be told. It is a growing branch of chemical science which highlights the connection between information technology (engineering and biological) and chemistry. The author and co-workers of this publication launched molecular logic as an experimental field by publishing the first research in the primary literature in 1993 and are uniquely placed to recount how the field has grown. There is no other book at present on molecular logic and computation and is more comprehensive than that found in any review available so far. It shows how designed molecules can play the role of information processors in a wide variety of situations, once we are educated by those information processors already available in the semiconductor electronics business and in the natural world. Following a short history of the field, is a set of primers on logic, computing and photochemical principles which are an essential basis in this field. The book covers all of the Boolean logic gates driven by a single input and all of those with double inputs and the wide range of designs which lie beneath these gates is a particular highlight. The easily-available diversity of chemical systems is another highlight, especially when it leads to reconfigurable logic gates. Further on in the book, molecular arithmetic and other more complex logic operations, including those with a memory and those which stray beyond binary are covered. Then follows molecular computing approaches which lie outside the Boolean blueprint, including quantum phenomena and finally, the book catalogues the useful real-life applications of molecular logic and computation which are already available. This book is an authoritative, state of the art, reference and a 'one-stop-shop' concerning the current state of the field for scientists, academics and postgraduate students.

Molecular Logic and Computational Synthetic Biology

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Author :
Publisher : Springer
ISBN 13 : 3030194329
Total Pages : 157 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Molecular Logic and Computational Synthetic Biology by : Madalena Chaves

Download or read book Molecular Logic and Computational Synthetic Biology written by Madalena Chaves and published by Springer. This book was released on 2019-04-27 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects the revised selected proceedings of the First International Symposium in Molecular Logic and Computational Synthetic Biology ( MLCSB), held in Chile, Santiago, in December 2018. The volume contains 7 full revised papers along with 2 surveys from 19 submissions presented at the symposium. One of the goals of the MLCSB 2018 was to explore the potential of molecular logic frameworks to study the emerging behavioural patterns in biological networks, combining discrete, continuous and stochastic features, and resorting both to specific or general-purpose analysis and verification techniques.

DNA- and RNA-Based Computing Systems

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Publisher : John Wiley & Sons
ISBN 13 : 3527347208
Total Pages : 408 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis DNA- and RNA-Based Computing Systems by : Evgeny Katz

Download or read book DNA- and RNA-Based Computing Systems written by Evgeny Katz and published by John Wiley & Sons. This book was released on 2021-04-12 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover the science of biocomputing with this comprehensive and forward-looking new resource DNA- and RNA-Based Computing Systems delivers an authoritative overview of DNA- and RNA-based biocomputing systems that touches on cutting-edge advancements in computer science, biotechnology, nanotechnology, and materials science. Accomplished researcher, academic, and author Evgeny Katz offers readers an examination of the intersection of computational, chemical, materials, and engineering aspects of biomolecular information processing. A perfect companion to the recently published Enzyme-Based Computing by the same editor, the book is an authoritative reference for those who hope to better understand DNA- and RNA-based logic gates, multi-component logic networks, combinatorial calculators, and related computational systems that have recently been developed for use in biocomputing devices. DNA- and RNA-Based Computing Systems summarizes the latest research efforts in this rapidly evolving field and points to possible future research foci. Along with an examination of potential applications in biosensing and bioactuation, particularly in the field of biomedicine, the book also includes topics like: A thorough introduction to the fields of DNA and RNA computing, including DNA/enzyme circuits A description of DNA logic gates, switches and circuits, and how to program them An introduction to photonic logic using DNA and RNA The development and applications of DNA computing for use in databases and robotics Perfect for biochemists, biotechnologists, materials scientists, and bioengineers, DNA- and RNA-Based Computing Systems also belongs on the bookshelves of computer technologists and electrical engineers who seek to improve their understanding of biomolecular information processing. Senior undergraduate students and graduate students in biochemistry, materials science, and computer science will also benefit from this book.

Enzyme-Based Computing Systems

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527345701
Total Pages : 420 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Enzyme-Based Computing Systems by : Evgeny Katz

Download or read book Enzyme-Based Computing Systems written by Evgeny Katz and published by John Wiley & Sons. This book was released on 2019-10-07 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This systematic and comprehensive overview of enzyme-based biocomputing is an excellent resource for scientists and engineers working on the design, study and applications of enzyme-logic systems.

Fluorescent polymers for sensing and imaging

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Publisher : MDPI
ISBN 13 : 3039369407
Total Pages : 208 pages
Book Rating : 4.0/5 (393 download)

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Book Synopsis Fluorescent polymers for sensing and imaging by : Seiichi Uchiyama

Download or read book Fluorescent polymers for sensing and imaging written by Seiichi Uchiyama and published by MDPI. This book was released on 2020-12-29 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowadays, all scientists recognize that fluorescent probes play important roles in wide research areas, from chemistry to biology. By combining this fact with specific functional benefits from synthetic polymers, fluorescent polymeric probes are occasionally superior to small organic and inorganic fluorescent (or luminescent) probes in terms of sensitivity, robustness, and multiple functionality. The targets of fluorescent polymeric probes have extended from chemical species to physical parameter. This special issue is a platform for researches to develop a novel fluorescent polymeric probe and to establish a new analytical method using a conventional fluorescent polymeric probe. Related researches, e.g., fluorometric investigation of functional polymers, are also included.

The Nature of the Mechanical Bond

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Publisher : John Wiley & Sons
ISBN 13 : 1119046750
Total Pages : 786 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis The Nature of the Mechanical Bond by : Carson J. Bruns

Download or read book The Nature of the Mechanical Bond written by Carson J. Bruns and published by John Wiley & Sons. This book was released on 2016-10-10 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: “The story is told by THE inventor-pioneer-master in the field and is accompanied by amazing illustrations… [it] will become an absolute reference and a best seller in chemistry!” Alberto Credi “… the great opus on the mechanical bond. A most impressive undertaking!” Jean-Marie Lehn Congratulations to co-author J. Fraser Stoddart, a 2016 Nobel Laureate in Chemistry. In molecules, the mechanical bond is not shared between atoms—it is a bond that arises when molecular entities become entangled in space. Just as supermolecules are held together by supramolecular interactions, mechanomolecules, such as catenanes and rotaxanes, are maintained by mechanical bonds. This emergent bond endows mechanomolecules with a whole suite of novel properties relating to both form and function. They hold unlimited promise for countless applications, ranging from their presence in molecular devices and electronics to their involvement in remarkably advanced functional materials. The Nature of the Mechanical Bond is a comprehensive review of much of the contemporary literature on the mechanical bond, accessible to newcomers and veterans alike. Topics covered include: Supramolecular, covalent, and statistical approaches to the formation of entanglements that underpin mechanical bonds in molecules and macromolecules Kinetically and thermodynamically controlled strategies for synthesizing mechanomolecules Chemical topology, molecular architectures, polymers, crystals, and materials with mechanical bonds The stereochemistry of the mechanical bond (mechanostereochemistry), including the novel types of dynamic and static isomerism and chirality that emerge in mechanomolecules Artificial molecular switches and machines based on the large-amplitude translational and rotational motions expressed by suitably designed catenanes and rotaxanes. This contemporary and highly interdisciplinary field is summarized in a visually appealing, image-driven format, with more than 800 illustrations covering both fundamental and applied research. The Nature of the Mechanical Bond is a must-read for everyone, from students to experienced researchers, with an interest in chemistry’s latest and most non-canonical bond. Read the Preface

Intracellular Thermometry with Fluorescent Molecular Thermometers

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527350322
Total Pages : 357 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Intracellular Thermometry with Fluorescent Molecular Thermometers by : Seiichi Uchiyama

Download or read book Intracellular Thermometry with Fluorescent Molecular Thermometers written by Seiichi Uchiyama and published by John Wiley & Sons. This book was released on 2024-06-17 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand a vital new bioanalytical technique with this comprehensive introduction to measuring temperature on the cellular scale Most organisms have highly controlled body temperatures, fluctuations in which are therefore sensitive indicators of changes in body function. In recent years, the development of fluorescent molecular thermometers and related intracellular temperature probes has enabled researchers to track these fluctuations at the cellular rather than the organismic level, opening up a whole new field of study in cell and molecular biology. Intracellular Thermometry with Fluorescent Molecular Thermometers provides bioanalytical researchers with an introduction to these technologies and their current and future applications. Starting off with a discussion of temperature as a key factor in biological regulation, it provides an authoritative overview of available fluorescent temperature probes, their characteristics and potential applications. Intracellular Thermometry with Fluorescent Molecular Thermometers readers will also find: Step by step instructions for constructing an intracellular thermometry experiment and validating results Comprehensive discussion of existing applications A vision for the future development of thermal biology as an independent discipline Authored by a pioneer in the field of intracellular thermometry, Intracellular Thermometry with Fluorescent Molecular Thermometers is ideal for researchers in analytical chemistry, cell biology, molecular biology, biophysics, or any related subjects.

Advances in Unconventional Computing

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Publisher : Springer
ISBN 13 : 3319339214
Total Pages : 812 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Advances in Unconventional Computing by : Andrew Adamatzky

Download or read book Advances in Unconventional Computing written by Andrew Adamatzky and published by Springer. This book was released on 2016-07-26 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: The unconventional computing is a niche for interdisciplinary science, cross-bred of computer science, physics, mathematics, chemistry, electronic engineering, biology, material science and nanotechnology. The aims of this book are to uncover and exploit principles and mechanisms of information processing in and functional properties of physical, chemical and living systems to develop efficient algorithms, design optimal architectures and manufacture working prototypes of future and emergent computing devices. This second volume presents experimental laboratory prototypes and applied computing implementations. Emergent molecular computing is presented by enzymatic logical gates and circuits, and DNA nano-devices. Reaction-diffusion chemical computing is exemplified by logical circuits in Belousov-Zhabotinsky medium and geometrical computation in precipitating chemical reactions. Logical circuits realised with solitons and impulses in polymer chains show advances in collision-based computing. Photo-chemical and memristive devices give us a glimpse on hot topics of a novel hardware. Practical computing is represented by algorithms of collective and immune-computing and nature-inspired optimisation. Living computing devices are implemented in real and simulated cells, regenerating organisms, plant roots and slime mould. The book is the encyclopedia, the first ever complete authoritative account, of the theoretical and experimental findings in the unconventional computing written by the world leaders in the field. All chapters are self-contains, no specialist background is required to appreciate ideas, findings, constructs and designs presented. This treatise in unconventional computing appeals to readers from all walks of life, from high-school pupils to university professors, from mathematicians, computers scientists and engineers to chemists and biologists.

Molecular and Supramolecular Information Processing

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Publisher : John Wiley & Sons
ISBN 13 : 3527645454
Total Pages : 403 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Molecular and Supramolecular Information Processing by : Evgeny Katz

Download or read book Molecular and Supramolecular Information Processing written by Evgeny Katz and published by John Wiley & Sons. This book was released on 2013-02-14 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by a renowned and much cited chemist, this book covers the whole span of molecular computers that are based on non-biological systems. The contributions by all the major scientists in the field provide an excellent overview of the latest developments in this rapidly expanding area. A must-have for all researchers working on this very hot topic. Perfectly complements Biomolecular Information Processing, also by Prof. Katz, and available as a two-volume set.

Architecture and Design of Molecule Logic Gates and Atom Circuits

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Publisher : Springer Science & Business Media
ISBN 13 : 3642331378
Total Pages : 284 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Architecture and Design of Molecule Logic Gates and Atom Circuits by : Nicolas Lorente

Download or read book Architecture and Design of Molecule Logic Gates and Atom Circuits written by Nicolas Lorente and published by Springer Science & Business Media. This book was released on 2013-02-01 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Have you ever puzzled over how to perform Boolean logic at the atomic scale? Or wondered how you can carry out more general calculations in one single molecule or using a surface dangling bond atomic scale circuit? This volume gives you an update on the design of single molecule devices, such as recitfiers, switches and transistors, more advanced semi-classical and quantum boolean gates integrated in a single molecule or constructed atom by atom on a passivated semi-conductor surface and describes their interconnections with adapted nano-scale wiring. The main contributors to the field of single molecule logic gates and surface dangling bond atomic scale circuits theory and design, were brought together for the first time to contribute on topics such as molecule circuits, surface dangling bond circuits, quantum controlled logic gates and molecular qubits. Contributions in this volume originate from the Barcelona workshop of the AtMol conference series, held from January 12-13 2012.

Approaching human intelligence through chemical systems: Development of unconventional chemical artificial intelligence

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832539947
Total Pages : 102 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Approaching human intelligence through chemical systems: Development of unconventional chemical artificial intelligence by : Pier Luigi Gentili

Download or read book Approaching human intelligence through chemical systems: Development of unconventional chemical artificial intelligence written by Pier Luigi Gentili and published by Frontiers Media SA. This book was released on 2023-11-27 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although human intelligence is deeply investigated by neuroscientists, psychologists, philosophers, and AI researchers, we still lack of a widely accepted definition of what it is. If we exploit the emergence theory from Complexity Science to give a definition, we might state that human intelligence is the emergent property of the human nervous system. Such fascinating emergent property allows us to handle both accurate and vague information by computing with numbers and words. Moreover, it allows us to reason, speak and take rational decisions in an environment of uncertainty, partiality and relativity of truth, when the “Incompatibility Principle” holds: “As the complexity of a system increases, accuracy and significance become almost mutually exclusive characteristics of our statements”. Finally, our intelligence allows us recognizing quite easily variable patterns. Therefore, it is worthwhile investigating human intelligence and trying to mimic it by developing Artificial Intelligence. Nowadays, Artificial Intelligence is in vogue: it is applied in both basic and applied science. Traditionally, there are two strategies to develop Artificial Intelligence. A strategy consists in writing human-like intelligent software running in von Neumann computers or special-purpose hardware. The other strategy consists in neuromorphic engineering. Neuromorphic engineering implements surrogates of neurons through non-biological systems, either for neuro-prosthesis or to design brain-like computing machines. A third strategy is now blooming and it consists in using molecular, supramolecular, materials, and systems chemistry to mimic some basic functions of human intelligence such as Boolean, multi-valued logic gates, and Fuzzy logic. This third strategy is originating Chemical Artificial Intelligence (CAI). A relevant purpose of CAI is to design modules for Chemical Robots. A Chemical Robot is thought of as a molecular assembly that reacts autonomously to its environment by probing it with molecular sensors, making decisions by its intrinsic Artificial Neural Networks or logic gates, and performing actions upon its environment through molecular effectors. The intelligent activities of any Chemical Robot should be sustained energetically by a metabolic unit. Chemical Robots should be easily miniaturized and implanted in living beings to interplay with cells or organelles for biomedical applications. They should become auxiliary elements of the natural immune system.

Women in Science: Chemistry

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Publisher : Frontiers Media SA
ISBN 13 : 2889742989
Total Pages : 478 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Women in Science: Chemistry by : Jennifer L. Schaefer

Download or read book Women in Science: Chemistry written by Jennifer L. Schaefer and published by Frontiers Media SA. This book was released on 2022-02-08 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt:

DNA Computing and Molecular Programming

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Publisher : Springer
ISBN 13 : 3030268071
Total Pages : 237 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis DNA Computing and Molecular Programming by : Chris Thachuk

Download or read book DNA Computing and Molecular Programming written by Chris Thachuk and published by Springer. This book was released on 2019-07-30 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 25th International Conference on DNA Computing and Molecular Programming, DNA 25, held in Seattle, WA, USA, in August 2019. The 12 full papers presented were carefully selected from 19 submissions. The papers cover a wide range of topics relating to biomolecular computing such as algorithms and models for computation on biomolecular systems; computational processes in vitro and in vivo; molecular switches, gates, devices, and circuits; molecular folding and self-assembly of nanostructures; analysis and theoretical models of laboratory techniques; molecular motors and molecular robotics; information storage; studies of fault-tolerance and error correction; software tools for analysis, simulation, anddesign; synthetic biology and in vitro evolution; and applications in engineering, physics, chemistry, biology, and medicine.

Computational Quantum Chemistry

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Publisher : Royal Society of Chemistry
ISBN 13 : 1782625860
Total Pages : 284 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Computational Quantum Chemistry by : Joseph J W McDouall

Download or read book Computational Quantum Chemistry written by Joseph J W McDouall and published by Royal Society of Chemistry. This book was released on 2015-11-09 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Quantum Chemistry presents computational electronic structure theory as practised in terms of ab initio waveform methods and density functional approaches. Getting a full grasp of the field can often prove difficult, since essential topics fall outside of the scope of conventional chemistry education. This professional reference book provides a comprehensive introduction to the field. Postgraduate students and experienced researchers alike will appreciate Joseph McDouall's engaging writing style. The book is divided into five chapters, each providing a major aspect of the field. Electronic structure methods, the computation of molecular properties, methods for analysing the output from computations and the importance of relativistic effects on molecular properties are also discussed. Links to the websites of widely used software packages are provided so that the reader can gain first hand experience of using the techniques described in the book. Dr McDouall has more than 25 years experience in theoretical chemistry; as a reader at the University of Manchester his research interests include the application of quantum chemical methods to the elucidation of chemical problems and the development and implementation of electronic structure methods that permit the accurate prediction of chemical structures and molecular properties.

Computational Techniques in Quantum Chemistry and Molecular Physics

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Publisher : Springer Science & Business Media
ISBN 13 : 9401018154
Total Pages : 570 pages
Book Rating : 4.4/5 (1 download)

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Book Synopsis Computational Techniques in Quantum Chemistry and Molecular Physics by : Geerd H.F. Diercksen

Download or read book Computational Techniques in Quantum Chemistry and Molecular Physics written by Geerd H.F. Diercksen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the transcripts of the lectures presented at the NATO Advanced study Institute on "Computational Techniques in Quantum Chemistry and Molecular Physics", held at Ramsau, Germany, 4th - 21st Sept. 1974. Quantum theory was developed in the early decades of this century and was first applied to problems in chemistry and molecular physics as early as 1927. It soon emerged however, that it was impossible to con sider any but the simplest systems in any quantita tive detail because of the complexity of Schrodinger's equation which is the basic equation for chemical and molecular physics applications. This remained the si tuation until the development, after 1950, of elec tronic digital computers. It then became possible to attempt approximate solutions of Schrodinger's equa tion for fairly complicated systems, to yield results which were sufficiently accurate to make comparison with experiment meaningful. Starting in the early nineteen sixties in the United States at a few centres with access to good computers an enormous amount of work went into the development and implementation of schemes for approximate solu tions of Schrodinger's equation, particularly the de velopment of the Hartree-Fock self-consistent-field scheme. But it was soon found that the integrals needed for application of the methods to molecular problems are far from trivial to evaluate and cannot be easily approximated.

Pattern Recognition in Computational Molecular Biology

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Publisher : John Wiley & Sons
ISBN 13 : 1118893689
Total Pages : 654 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Pattern Recognition in Computational Molecular Biology by : Mourad Elloumi

Download or read book Pattern Recognition in Computational Molecular Biology written by Mourad Elloumi and published by John Wiley & Sons. This book was released on 2015-12-29 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of high-performance pattern recognition techniques and approaches to Computational Molecular Biology This book surveys the developments of techniques and approaches on pattern recognition related to Computational Molecular Biology. Providing a broad coverage of the field, the authors cover fundamental and technical information on these techniques and approaches, as well as discussing their related problems. The text consists of twenty nine chapters, organized into seven parts: Pattern Recognition in Sequences, Pattern Recognition in Secondary Structures, Pattern Recognition in Tertiary Structures, Pattern Recognition in Quaternary Structures, Pattern Recognition in Microarrays, Pattern Recognition in Phylogenetic Trees, and Pattern Recognition in Biological Networks. Surveys the development of techniques and approaches on pattern recognition in biomolecular data Discusses pattern recognition in primary, secondary, tertiary and quaternary structures, as well as microarrays, phylogenetic trees and biological networks Includes case studies and examples to further illustrate the concepts discussed in the book Pattern Recognition in Computational Molecular Biology: Techniques and Approaches is a reference for practitioners and professional researches in Computer Science, Life Science, and Mathematics. This book also serves as a supplementary reading for graduate students and young researches interested in Computational Molecular Biology.

Ribozymes

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Publisher : John Wiley & Sons
ISBN 13 : 3527814531
Total Pages : 81 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Ribozymes by : Sabine Müller

Download or read book Ribozymes written by Sabine Müller and published by John Wiley & Sons. This book was released on 2021-07-09 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ribozymes Provides comprehensive coverage of a core field in the molecular biosciences, bringing together decades of knowledge from the world’s top professionals in the field Timely and unique in its breadth of content, this all-encompassing and authoritative reference on ribozymes documents the great diversity of nucleic acid-based catalysis. It integrates the knowledge gained over the past 35 years in the field and features contributions from virtually every leading expert on the subject. Ribozymes is organized into six major parts. It starts by describing general principles and strategies of nucleic acid catalysis. It then introduces naturally occurring ribozymes and includes the search for new catalytic motifs or novel genomic locations of known motifs. Next, it covers the development and design of engineered ribozymes, before moving on to DNAzymes as a close relative of ribozymes. The next part examines the use of ribozymes for medicinal and environmental diagnostics, as well as for therapeutic tools. It finishes with a look at the tools and methods in ribozyme research, including the techniques and assays for structural and functional characterization of nucleic acid catalysts. The first reference to tie together all aspects of the multi-faceted field of ribozymes Features more than 30 comprehensive chapters in two volumes Covers the chemical principles of RNA catalysis; naturally occurring ribozymes, engineered ribozymes; DNAzymes; ribozymes as tools in diagnostics and therapy, and tools and methods to study ribozymes Includes first-hand accounts of concepts, techniques, and applications by a team of top international experts from leading academic institutions Dedicates half of its content to methods and practical applications, ranging from bioanalytical tools to medical diagnostics to therapeutics Ribozymes is an unmatched resource for all biochemists, biotechnologists, molecular biologists, and bioengineers interested in the topic.