Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Molecular Infection Biology
Download Molecular Infection Biology full books in PDF, epub, and Kindle. Read online Molecular Infection Biology ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Molecular Infection Biology by : Jörg Hinrich Hacker
Download or read book Molecular Infection Biology written by Jörg Hinrich Hacker and published by Wiley-Spektrum. This book was released on 2002-10-03 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume focuses on molecular methods and principles of prokaryotic and eukaryotic pathogens. The authors present the molecular and cellular aspects by focusing on the interactions between pathogenic microorganisms and their hosts. The publication begins with an overview of the most important and dangerous causative agents of infectious diseases. Next are discussions of how microbial "weapons," pathogenicity factors, protein secretion machines, and surface variation systems work, presenting the molecular and genetic methods that are used by scientists for their discovery and analysis. Furthermore, infectious diseases are discussed in light of the newly formed research areas of evolutionary and cellular microbiology and genomics. Future aspects on diagnostic techniques, therapy, and vaccine development are also presented.
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular Infection Biology by : J Rg Hacker
Download or read book Molecular Infection Biology written by J Rg Hacker and published by . This book was released on 2002-10-01 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions by : Seyed Ehtesham Hasnain
Download or read book Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions written by Seyed Ehtesham Hasnain and published by Springer Nature. This book was released on 2019-11-30 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews recent advances in the molecular and infection biology, pathology, and molecular epidemiology of Mycobacterium tuberculosis, as well as the identification and validation of novel molecular drug targets for the treatment of this mycobacterial disease. Despite being completely curable, tuberculosis is still one of the leading global causes of death. M. tuberculosis, the causative organism – one of the smartest pathogens known – adopts highly intelligent strategies for survival and pathogenesis. Presenting a wealth of information on the molecular infection biology of M. tuberculosis, as well as nontuberculous mycobacteria (NTM), the book provides an overview of the functional role of the PE/PPE group of proteins, which is exclusive to the genus Mycobacteria, of host-pathogen interactions, and virulence. It also explores the pathogenesis of the infection, pathology, epidemiology, and diagnosis of NTM. Finally it discusses current and novel approaches in vaccine development against tuberculosis, including the role of nanotechnology. With state-of-the-art contributions from experts in the respective domains, this book is an informative resource for practitioners as well as medical postgraduate students and researchers.
Book Synopsis Molecular Typing in Bacterial Infections by : Ivano de Filippis
Download or read book Molecular Typing in Bacterial Infections written by Ivano de Filippis and published by Springer Science & Business Media. This book was released on 2012-11-07 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Typing in Bacterial Infections covers common bacterial pathogenic agents, with the most effective methods for their identification and classification in the light of their specific epidemiology. The book will be a valuable resource for molecular typing of infectious diseases agents encountered in both the research and hospital clinical lab settings, as well as culture collections. Each chapter provides an overview of molecular approaches to typing bacterial pathogens. Part I gives a general overview of typing methods used in the traditional microbiology laboratory in comparison to molecular methods of epidemiology. In Part II, the relative strengths and weaknesses of the different methods applicable to the specific agents of infectious diseases are emphasized. Specific emphasis is placed on recent changes and updates in molecular typing.
Book Synopsis Veterinary Infection Biology: Molecular Diagnostics and High-Throughput Strategies by : Mónica V. Cunha
Download or read book Veterinary Infection Biology: Molecular Diagnostics and High-Throughput Strategies written by Mónica V. Cunha and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an overview of molecular biology tools for pathogen detection and characterization. Focusing on biobanking, biosafety, good laboratory practices, biological specimen collection and processing, quality assurance and control, validation of molecular diagnostic assays for veterinary use; molecular detection and identification of animal pathogens using a wide range of established techniques and covering, also, emerging diagnosis approaches; genotyping tools for assessing the genetic landscape and epidemiology of pathogens; and integrative omics and high-throughput technologies as powerful research tools. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Veterinary Infection Biology: Molecular Diagnostics and High-Throughput Strategies aids scientists in continuing to study a broad range of molecular approaches, from simple and affordable to emerging and sophisticate.
Book Synopsis Molecular and Cell Biology of Opportunistic Infections in AIDS by : S. Myint
Download or read book Molecular and Cell Biology of Opportunistic Infections in AIDS written by S. Myint and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human immunodeficiency virus and AIDS have received much attention in the last decade. As the major cause of death in young adults, this concern is merited. AIDS has also ushered onto the clinical agenda a number of unusual and interesting pathogens. These have had considerably less attention than the virus itself, but are arguably as important. This book attempts to put into one volume a state of the art review of the basic biology of these opportunistic organisms. When compiling this book, the perceived difficulty was deciding how to restrict the number of chapters, as there is a large number of opportunistic organisms. It soon became clear, however, that the chapters would select themselves, as the work on many of these organisms was still in its infancy. We can be criticized for including Salmonella, which is not thought to be an opportunistic infection, and excluding Cryptococcus. Our defence is that the former has an interesting relationship with HIV and the latter is one of those organisms for which the basic biology is still in its early stages. The authors are all active researchers in their respective fields and we are grateful that they managed to review their subjects in the short turn-around time required for a book such as this not to be needlessly outdated on publication. We hope that, if nothing else, this book stimulates interest and more research on these agents: perhaps, in future editions, there will be much more to describe on their molecular biology.
Book Synopsis What You Need to Know about Infectious Disease by : Madeline Drexler
Download or read book What You Need to Know about Infectious Disease written by Madeline Drexler and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Molecular Biology of Viruses by : John Colter
Download or read book The Molecular Biology of Viruses written by John Colter and published by Elsevier. This book was released on 2012-12-02 with total page 747 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Molecular Biology of Viruses is a collection of manuscripts presented at the Third Annual International Symposium of the Molecular Biology of Viruses, held in the University of Alberta, Canada on June 27-30, 1966, sponsored by the Faculty of Medicine of the University of Alberta. This book is organized into eight parts encompassing 36 chapters that emphasize the biosynthetic steps involved in polymer duplication. The first two parts explore the specialized processes of the cycle of virulent and temperate bacteriophage multiplication. These parts also deal with the production, regulation of development, and selectivity of these bacteriophages. The subsequent two parts look into the heterozygosity, mutation, structure, function, and mode of infection of single-stranded DNA and RNA bacteriophages. The discussions then shift to the biological and physicochemical aspects, biosynthesis, translation, genetics, and replication of mammalian DNA and RNA viruses. The concluding parts describe the homology, interaction, functions, mechanism of transformation, metabolism, and carcinogenic activity of oncogenic viruses. This book is of great benefit to biochemists, biophysicists, geneticists, microbiologists, and virologists.
Book Synopsis Candida Albicans by : Rajendra Prasad
Download or read book Candida Albicans written by Rajendra Prasad and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Candida, which was discovered more than a century ago as a causative organism of oral thrush, is now thought to potentially infect almost every tissue of the human body. Although we still do not have a safe anti-candida drug, the growing pace of progess of research on Candida albicans holds promise that a breakthrough is imminent. Though many monographs and articles on candida and candidoses have appeared in recent years, they mostly cover the clinical aspects. This particular text, however, explains the more basic features of candida including the molecular genetics, molecular biology and immunology of the cell wall, the molecular basis of morphogenesis and the structure and function of the plasma membrane. The role of anti-candida drugs and their mechanism of action are also discussed.
Book Synopsis Molecular and Cellular Biology of Viruses by : Phoebe Lostroh
Download or read book Molecular and Cellular Biology of Viruses written by Phoebe Lostroh and published by CRC Press. This book was released on 2024-03-25 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully revised second edition of Molecular and Cellular Biology of Viruses leads students on an exploration of viruses by supporting engaging and interactive learning. All the major classes of viruses are covered, with separate chapters for their replication and expression strategies, and chapters for mechanisms such as attachment that are independent of the virus genome type. Specific cases drawn from primary literature foster student engagement. End-of-chapter questions focus on analysis and interpretation with answers being given at the back of the book. Examples come from the most-studied and medically important viruses such as SARS-CoV-2, HIV, and influenza. Plant viruses and bacteriophages are also included. There are chapters on the overall effect of viral infection on the host cell. Coverage of the immune system is focused on the interplay between host defenses and viruses, with a separate chapter on medical applications such as antiviral drugs and vaccine development. The final chapter is on virus diversity and evolution, incorporating contemporary insights from metagenomic research. The second edition has updated suggestions for primary literature to discuss along with each chapter. New to this second edition, a supplementary chapter, freely available for download, looks at how virology intersects with public health, and uses the COVID-19 pandemic as a notable example. Key Features Readable but rigorous coverage of the molecular and cellular biology of viruses Molecular mechanisms of all major groups, including plant viruses and bacteriophages, illustrated by example Host-pathogen interactions at the cellular and molecular level emphasized throughout Medical implications and consequences included Quality illustrations available to instructors New to this second edition, interactive quiz questions hosted online
Book Synopsis Janeway's Immunobiology by : Kenneth Murphy
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Book Synopsis The Baculoviruses by : Lois K. Miller
Download or read book The Baculoviruses written by Lois K. Miller and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has witnessed an explosion of information on the molecular biology of insect viruses and a frenzy of activity in applying this information to medicine and agriculture. Genetically engineered baculoviruses are presently being tested for commercial use as pesticides, and the study of such viruses is also revealing remarkable insights into basic cellular processes such as apoptosis. This comprehensive volume provides readers with knowledge of basic and applied baculovirology so that current literature in the field can be appreciated.
Book Synopsis Molecular Biology of the SARS-Coronavirus by : Sunil K. Lal
Download or read book Molecular Biology of the SARS-Coronavirus written by Sunil K. Lal and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: SARS was the ?rst new plague of the twenty-?rst century. Within months, it spread worldwide from its “birthplace” in Guangdong Province, China, affecting over 8,000 people in 25 countries and territories across ?ve continents. SARS exposed the vulnerability of our modern globalised world to the spread of a new emerging infection. SARS (or a similar new emerging disease) could neither have spread so rapidly nor had such a great global impact even 50 years ago, and arguably, it was itself a product of our global inter-connectedness. Increasing af?uence and a demand for wild-game as exotic food led to the development of large trade of live animal and game animal markets where many species of wild and domestic animals were co-housed, providing the ideal opportunities for inter-species tra- mission of viruses and other microbes. Once such a virus jumped species and attacked humans, the increased human mobility allowed the virus the opportunity for rapid spread. An infected patient from Guangdong who stayed for one day at a hotel in Hong Kong led to the transmission of the disease to 16 other guests who travelled on to seed outbreaks of the disease in Toronto, Singapore, and Vietnam, as well as within Hong Kong itself. The virus exploited the practices used in modern intensive care of patients with severe respiratory disease and the weakness in infection control practices within our health care systems to cause outbreaks within hospitals, further amplifying the spread of the disease. Health-care itself has become a two-edged sword.
Author :Committee on the Assessment of Future Scientific Needs for Variola Virus Publisher :National Academies Press ISBN 13 :030959698X Total Pages :126 pages Book Rating :4.3/5 (95 download)
Book Synopsis Assessment of Future Scientific Needs for Live Variola Virus by : Committee on the Assessment of Future Scientific Needs for Variola Virus
Download or read book Assessment of Future Scientific Needs for Live Variola Virus written by Committee on the Assessment of Future Scientific Needs for Variola Virus and published by National Academies Press. This book was released on 1999-05-14 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1980, the World Health Organization (WHO) officially declared that smallpox had been eradicated. In 1986, WHO's international Ad Hoc Committee on Orthopox Virus Infections unanimously recommended destruction of the two remaining official stocks of variola virus, one at the Centers for Disease Control and Prevention and the other at the VECTOR laboratory in Siberia. In June 1999, WHO decided to delay the destruction of these stocks. Informing that decision was Assessment of Future Scientific Needs for Variola Virus, which examines: -- Whether the sequenced variola genome, vaccinia, and monkey pox virus are adequate for future research or whether the live variola virus itself is needed to assist in the development of antiviral therapies. -- What further benefits, if any, would likely be gained through the use of variola in research and development efforts related to agent detection, diagnosis, prevention, and treatment. -- What unique potential benefits, if any, the study of variola would have in increasing our fundamental understanding of the biology, host-agent interactions, pathogenesis, and immune mechanisms of viral diseases.
Book Synopsis Systems Biology of Microbial Infection by : Reinhard Guthke
Download or read book Systems Biology of Microbial Infection written by Reinhard Guthke and published by Frontiers E-books. This book was released on with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: The systems biology of microbial infections aims at describing and analysing the confrontation of the host with bacterial and fungal pathogens. It intends to understand and to model the interaction of the host, in particular the immune system of humans or animals, with components of pathogens. This comprises experimental studies that provide spatio-temporal data from monitoring the response of host and pathogenic cells to perturbations or when interacting with each other, as well as the integrative analysis of genome-wide data from both the host and the pathogen. In perspective, the host-pathogen interaction should be described by a combination of spatio-temporal models with interacting molecular networks of the host and the pathogen. The aim is to unravel the main mechanisms of pathogenicity, to identify diagnostic biomarkers and potential drug targets, and to explore novel strategies for personalized therapy by computer simulations. Some microorganisms are part of the normal microbial flora, existing either in a mutualistic or commensal relationship with the host. Microorganisms become pathogenic if they posses certain physiological characteristics and virulence determinants as well as capabilities for immune evasion. Despite the different pathogenesis of infections, there are several common traits: (1) Before infection, pathogens must be able to overcome (epithelial) barriers. The infection starts by adhesion and colonization and is followed by entering of the pathogen into the host through the mucosa or (injured) skin. (2) Next, infection arises if the pathogen multiplies and overgrows the normal microbial flora, either at the place of entrance or in deeper tissue layers or organs. (3) After the growth phase, the pathogen damages the host’s cells, tissues and organs by producing toxins or destructive enzymes. Thus, systems biology of microbial infection comprises all levels of the pathogen and the host’s immune system. The investigation may start with the pathogen, its adhesion and colonization at the host, its interaction with host cell types e.g. epithelia cells, dendritic cells, macrophages, neutrophils, natural killer cells, etc. Because infection diseases are mainly found in patients with a weakened immune system, e.g. reduced activities of immune effector cells or defects in the epithelial barriers, systems biology of infection can also start with modelling of the immune defence including innate and adaptive immunity. Systems biological studies comprise both experimental and theoretical approaches. The experimental studies may be dedicated to reveal the relevance of certain genes or proteins in the above mentioned processes on the side of the pathogen and/or the host by applying functional and biochemical analyses based on knock-out mutants and knock- down experiments. At the theoretical, i.e. mathematical and computational, side systems biology of microbial infection comprises: (1) modelling of molecular mechanisms of bacterial or fungal infections, (2) modelling of non-protective and protective immune defences against microbial pathogens to generate information for possible immune therapy approaches, (3) modelling of infection dynamics and identification of biomarkers for diagnosis and for individualized therapy, (4) identifying essential virulence determinants and thereby predicting potential drug targets.
Book Synopsis The Molecular Basis of Viral Infection by : P. J Klasse
Download or read book The Molecular Basis of Viral Infection written by P. J Klasse and published by Academic Press. This book was released on 2015-01-08 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virology is in a sense both one of the most important precursors and one of the most significant beneficiaries of structural and cellular molecular biology. Numerous breakthroughs in our understanding of the molecular interactions of viruses with host cells are ready for translation into medically important applications such as the prevention and treatment of viral infections. This book collects a wide variety of examples of frontline research into molecular aspects of viral infections from virological, immunological, cell- and molecular-biological, structural, and theoretical perspectives. Contributors are world leaders in their fields of study and represent prestigious academic and research institutions Review articles vary vastly in scope: some focus on a narrowly defined scientific problem of one particular virus with careful introduction for the non-specialist; others are essays in general and comparative virology with forays into specific viral species or molecules The different perspectives complement each other and collectively the contributions provide an impression of the fast-moving frontlines of virology while showing how the problems have evolved Structural data are presented through high-quality illustrations
