Molecular Imaging Basic Principles And Applications In Biomedical Research 2nd Edition

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Molecular Imaging: Basic Principles And Applications In Biomedical Research (2nd Edition)

Author : Rudin Markus
Publisher : World Scientific
ISBN 13 : 1783263172
Total Pages : 620 pages
Book Rating : 4.7/5 (832 download)

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Book Synopsis Molecular Imaging: Basic Principles And Applications In Biomedical Research (2nd Edition) by : Rudin Markus

Download or read book Molecular Imaging: Basic Principles And Applications In Biomedical Research (2nd Edition) written by Rudin Markus and published by World Scientific. This book was released on 2013-07-04 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied. The final chapter deals with visualization of cell migration, for example in the context of cell therapies.The second edition covers novel developments over recent years, in particular regarding imaging technologies (hybrid techniques) and novel reporter concepts. Novel biomedical applications have been included, where appropriate. All the chapters have been thoroughly reworked and the artwork updated.

Molecular Imaging: Basic Principles And Applications In Biomedical Research (3rd Edition)

Author : Markus Rudin
Publisher : World Scientific
ISBN 13 : 1786346869
Total Pages : 801 pages
Book Rating : 4.7/5 (863 download)

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Book Synopsis Molecular Imaging: Basic Principles And Applications In Biomedical Research (3rd Edition) by : Markus Rudin

Download or read book Molecular Imaging: Basic Principles And Applications In Biomedical Research (3rd Edition) written by Markus Rudin and published by World Scientific. This book was released on 2020-04-04 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied.The third edition has been extended considerably. This holds for the chapter on imaging modalities, which now includes sections on intravital microscopy and mass spectrometric imaging. All chapters have been updated and a new chapter on the challenges of translating molecular imaging solutions for clinical use has been added.

Molecular Imaging

Author : Jie Tian
Publisher : Springer Science & Business Media
ISBN 13 : 3642343031
Total Pages : 699 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Molecular Imaging by : Jie Tian

Download or read book Molecular Imaging written by Jie Tian and published by Springer Science & Business Media. This book was released on 2013-07-23 with total page 699 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Molecular Imaging: Fundamentals and Applications" is a comprehensive monograph which describes not only the theory of the underlying algorithms and key technologies but also introduces a prototype system and its applications, bringing together theory, technology and applications. By explaining the basic concepts and principles of molecular imaging, imaging techniques, as well as research and applications in detail, the book provides both detailed theoretical background information and technical methods for researchers working in medical imaging and the life sciences. Clinical doctors and graduate students will also benefit from this book. Jie Tian is a professor at the Institute of Automation, Chinese Academy of Sciences, China.

Molecular Imaging

Author : Brian D. Ross
Publisher : Academic Press
ISBN 13 : 0128163879
Total Pages : 1872 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Molecular Imaging by : Brian D. Ross

Download or read book Molecular Imaging written by Brian D. Ross and published by Academic Press. This book was released on 2021-08-03 with total page 1872 pages. Available in PDF, EPUB and Kindle. Book excerpt: The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field. The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data Concepts illustrated with over 600 color figures and molecular-imaging examples Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications

Molecular Imaging

Author : Jie Tian
Publisher : Springer
ISBN 13 : 9783642343049
Total Pages : 699 pages
Book Rating : 4.3/5 (43 download)

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Book Synopsis Molecular Imaging by : Jie Tian

Download or read book Molecular Imaging written by Jie Tian and published by Springer. This book was released on 2014-06-11 with total page 699 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Molecular Imaging: Fundamentals and Applications" is a comprehensive monograph which describes not only the theory of the underlying algorithms and key technologies but also introduces a prototype system and its applications, bringing together theory, technology and applications. By explaining the basic concepts and principles of molecular imaging, imaging techniques, as well as research and applications in detail, the book provides both detailed theoretical background information and technical methods for researchers working in medical imaging and the life sciences. Clinical doctors and graduate students will also benefit from this book. Jie Tian is a professor at the Institute of Automation, Chinese Academy of Sciences, China.

Molecular Imaging

Author : Ralph Weissleder
Publisher : PMPH-USA
ISBN 13 : 9781607950059
Total Pages : 1384 pages
Book Rating : 4.9/5 (5 download)

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Book Synopsis Molecular Imaging by : Ralph Weissleder

Download or read book Molecular Imaging written by Ralph Weissleder and published by PMPH-USA. This book was released on 2010 with total page 1384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.

Statistical Computing in Nuclear Imaging

Author : Arkadiusz Sitek
Publisher : CRC Press
ISBN 13 : 1498729304
Total Pages : 264 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Statistical Computing in Nuclear Imaging by : Arkadiusz Sitek

Download or read book Statistical Computing in Nuclear Imaging written by Arkadiusz Sitek and published by CRC Press. This book was released on 2014-12-17 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Computing in Nuclear Imaging introduces aspects of Bayesian computing in nuclear imaging. The book provides an introduction to Bayesian statistics and concepts and is highly focused on the computational aspects of Bayesian data analysis of photon-limited data acquired in tomographic measurements. Basic statistical concepts, elements of

Molecular Imaging of Small Animals

Author : Habib Zaidi
Publisher : Springer
ISBN 13 : 1493908944
Total Pages : 760 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Molecular Imaging of Small Animals by : Habib Zaidi

Download or read book Molecular Imaging of Small Animals written by Habib Zaidi and published by Springer. This book was released on 2014-05-27 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the fundamental concepts of multimodality small-animal molecular imaging technologies and their numerous applications in biomedical research. Driven primarily by the widespread availability of various small-animal models of human diseases replicating accurately biological and biochemical processes in vivo, this is a relatively new yet rapidly expanding field that has excellent potential to become a powerful tool in biomedical research and drug development. In addition to being a powerful clinical tool, a number of imaging modalities including but not limited to CT, MRI, SPECT and PET are also used in small laboratory animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease and neurological disorders in living small animal models of disease. In vivo small-animal imaging is playing a pivotal role in the scientific research paradigm enabling to understand human molecular biology and pathophysiology using, for instance, genetically engineered mice with spontaneous diseases that closely mimic human diseases.

Molecular Imaging

Author : Alexei Bogdanov
Publisher : Springer Science & Business Media
ISBN 13 : 354026809X
Total Pages : 269 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Molecular Imaging by : Alexei Bogdanov

Download or read book Molecular Imaging written by Alexei Bogdanov and published by Springer Science & Business Media. This book was released on 2007-01-19 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: The continuous progress in the understanding of molecular processes of disease formation and progression attributes an increasing importance to biomedical molecular imaging methods. The purpose of this workshop was to discuss and overview multiple applications and emerging technologies in the area of diagnostic imaging including its fundamental capabilities in preclinical research, the opportunities for medical care, and the options involving therapeutic concepts. The book provides the reader with state-of-the-art information on the different aspects of diagnostic imaging, illuminating new developments in molecular biology, imaging agents and molecular probe design, and therapeutic techniques.

Targeted Molecular Imaging

Author : Michael J. Welch
Publisher : CRC Press
ISBN 13 : 1439841950
Total Pages : 390 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Targeted Molecular Imaging by : Michael J. Welch

Download or read book Targeted Molecular Imaging written by Michael J. Welch and published by CRC Press. This book was released on 2012-02-24 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted Molecular Imaging covers the development of novel diagnostic approaches that use an imaging probe and agent to noninvasively visualize cellular processes in normal and disease states. It discusses the concept, development, preclinical studies, and, in many cases, translation to the clinic of targeted imaging agents. The many case studies that form the core of this book deal with the development and translation of non-nuclear probes and radiotracers; other sections address critical topics such as In vitro studies, small animal research, and the application of targeted probes for nuclear, optical and MRI imaging. The chapters use a common format to demonstrate how various investigators approach the comprehensive task of validating a new targeted probe. Targeted Molecular Imaging is a timely resource for a rapidly advancing field, and addresses: Various methods of validating a new targeted probe through examples from human studies with imaging of breast cancer, cardiovascular disease, and neurodegenerative diseases Basic principles, disease models, imaging studies in animals, imaging in initial human studies, and the application of molecular imaging in pharmacy and drug discovery In vitro studies, small animal studies, and targeted radiopharmaceuticals Using these case studies, investigators can generalize and apply the information to their own specific targeted probe. The insights provided by the contributors, experts who have developed these approaches in their own groups, help guide scientists planning to translate imaging agents from the concept stage to clinical application.

Fluorescence Molecular Tomography

Author : Huabei Jiang
Publisher : Springer Nature
ISBN 13 : 3031100042
Total Pages : 135 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis Fluorescence Molecular Tomography by : Huabei Jiang

Download or read book Fluorescence Molecular Tomography written by Huabei Jiang and published by Springer Nature. This book was released on 2022-09-13 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorescence Molecular Tomography: Principles and Applications is the first book to cover the underlying principles and practical applications of fluorescence molecular tomography (FMT) in a systematic manner. Using a tutorial approach, the text begins with an overview of the fundamentals of FMT and goes on to detail image reconstruction approaches (including linear and nonlinear reconstruction algorithms), FMT instrumentations (including time-domain, frequency-domain, and continuous-wave domain systems), and implementation of image-enhancing schemes (including both software and hardware approaches). Further chapters examine multimodal approaches combining photoacoustic tomography (PAT), computed tomography (CT), single-photon emission tomography (SPECT), and magnetic resonance imaging (MRI) and discuss bioluminescence tomography and miniaturized FMT from hand-held to endoscopic FMT. A final chapter looks at clinical applications and animal studies. This authoritative and practical guide will serve as a valuable reference for researchers, scientists, clinicians, and industry professionals. The first book dedicated to fluorescence molecular tomography (FMT); Covers underlying principles and practical applications; Written by a leading FMT research pioneer and expert.

Magnetic Resonance Imaging

Author : Robert W. Brown
Publisher : John Wiley & Sons
ISBN 13 : 0471720852
Total Pages : 976 pages
Book Rating : 4.4/5 (717 download)

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Book Synopsis Magnetic Resonance Imaging by : Robert W. Brown

Download or read book Magnetic Resonance Imaging written by Robert W. Brown and published by John Wiley & Sons. This book was released on 2014-06-23 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition explores contemporary MRI principles and practices Thoroughly revised, updated and expanded, the second edition of Magnetic Resonance Imaging: Physical Principles and Sequence Design remains the preeminent text in its field. Using consistent nomenclature and mathematical notations throughout all the chapters, this new edition carefully explains the physical principles of magnetic resonance imaging design and implementation. In addition, detailed figures and MR images enable readers to better grasp core concepts, methods, and applications. Magnetic Resonance Imaging, Second Edition begins with an introduction to fundamental principles, with coverage of magnetization, relaxation, quantum mechanics, signal detection and acquisition, Fourier imaging, image reconstruction, contrast, signal, and noise. The second part of the text explores MRI methods and applications, including fast imaging, water-fat separation, steady state gradient echo imaging, echo planar imaging, diffusion-weighted imaging, and induced magnetism. Lastly, the text discusses important hardware issues and parallel imaging. Readers familiar with the first edition will find much new material, including: New chapter dedicated to parallel imaging New sections examining off-resonance excitation principles, contrast optimization in fast steady-state incoherent imaging, and efficient lower-dimension analogues for discrete Fourier transforms in echo planar imaging applications Enhanced sections pertaining to Fourier transforms, filter effects on image resolution, and Bloch equation solutions when both rf pulse and slice select gradient fields are present Valuable improvements throughout with respect to equations, formulas, and text New and updated problems to test further the readers' grasp of core concepts Three appendices at the end of the text offer review material for basic electromagnetism and statistics as well as a list of acquisition parameters for the images in the book. Acclaimed by both students and instructors, the second edition of Magnetic Resonance Imaging offers the most comprehensive and approachable introduction to the physics and the applications of magnetic resonance imaging.

Molecular Imaging

Author : Shankar Vallabhajosula
Publisher : Springer Science & Business Media
ISBN 13 : 3540767355
Total Pages : 379 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Molecular Imaging by : Shankar Vallabhajosula

Download or read book Molecular Imaging written by Shankar Vallabhajosula and published by Springer Science & Business Media. This book was released on 2009-07-13 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.

Biomedical Imaging Instrumentation

Author : Mrutyunjay Suar
Publisher : Academic Press
ISBN 13 : 0323899919
Total Pages : 240 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Biomedical Imaging Instrumentation by : Mrutyunjay Suar

Download or read book Biomedical Imaging Instrumentation written by Mrutyunjay Suar and published by Academic Press. This book was released on 2021-11-26 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Imaging Instrumentation: Applications in Tissue, Cellular and Molecular Diagnostics provides foundational information about imaging modalities, reconstruction and processing, and their applications. The book provides insights into the fundamental of the important techniques in the biomedical imaging field and also discusses the various applications in the area of human health. Each chapter summarizes the overview of the technique, the various applications, and the challenges and recent innovations occurring to further improve the technique. Chapters include Biomedical Techniques in Cellular and Molecular Diagnostics, The Role of CT Scan in Medical and Dental Imaging, Ultrasonography - Technology & Applications in Clinical Radiology, Magnetic Resonance Imaging, Instrumentation and Utilization of PET-CT Scan in Oncology, Gamma Camera and SPECT, Sentinel of Breast Cancer Screening; Hyperspectral Imaging; PA Imaging; NIR Spectroscopy, and The Advances in Optical Microscopy and its Applications in Biomedical Research. This book is ideal for supporting learning, and is a key resource for students and early career researchers in fields such as medical imaging and biomedical instrumentation. A basic, fundamental, easy to understand introduction to medical imaging techniques Each technique is accompanied with detailed discussion on the application in the biomedical field in an accessible and easy to understand way Provides insights into the limitations of each technology and innovations that are occurring related to that technology

The Chemistry of Molecular Imaging

Author : Nicholas Long
Publisher : John Wiley & Sons
ISBN 13 : 1118854772
Total Pages : 408 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis The Chemistry of Molecular Imaging by : Nicholas Long

Download or read book The Chemistry of Molecular Imaging written by Nicholas Long and published by John Wiley & Sons. This book was released on 2014-12-01 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular imaging is primarily about the chemistry of novelbiological probes, yet the vast majority of practitioners are notchemists or biochemists. This is the first book, written from achemist's point of view, to address the nature of the chemicalinteraction between probe and environment to help elucidatebiochemical detail instead of bulk anatomy. Covers all of the fundamentals of modern imaging methodologies,including their techniques and application within medicine andindustry Focuses primarily on the chemistry of probes and imagingagents, and chemical methodology for labelling andbioconjugation First book to investigate the chemistry of molecularimaging Aimed at students as well as researchers involved in the areaof molecular imaging

Abstract Book of the International Congress on Health Sciences and Medical Technologies 2018

Author : Abdeldjalil KHELASSI
Publisher : Knowledge Kingdom Publishing
ISBN 13 : 9931944609
Total Pages : 38 pages
Book Rating : 4.9/5 (319 download)

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Book Synopsis Abstract Book of the International Congress on Health Sciences and Medical Technologies 2018 by : Abdeldjalil KHELASSI

Download or read book Abstract Book of the International Congress on Health Sciences and Medical Technologies 2018 written by Abdeldjalil KHELASSI and published by Knowledge Kingdom Publishing. This book was released on with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract Book of the International Congress on Health Sciences and Medical Technologies 2018

PET

Author : Michael E. Phelps
Publisher : Springer Science & Business Media
ISBN 13 : 0387225293
Total Pages : 622 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis PET by : Michael E. Phelps

Download or read book PET written by Michael E. Phelps and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is written as both a text and a reference book. It contains numerous images from the biological sciences and clinical practice, tables, graphs, and fig ures, as well as exercises that are worked out to aid the reader in understanding principles or solving problems. In some cases, derivations are placed in appen dices so as not to break up the flow of the subject matter in the text. The book is intended for a broad audience interested in molecular imaging with positron emission tomography (PET). It is expected that the readers will range from undergraduate, graduate, and medical students to residents, physi cians, and scientists with backgrounds from various physical, biological, and medical specialty areas. Each chapter presents material in a straightforward man ner that is well illustrated and explained. Because of the diverse audience for the book, certain chapters or sections of chapters will be of more interest than oth ers to certain segments of the readership. Chapter 1 introduces the fundamental physics upon which PET imaging sys tems is based and discusses in detail the technologies and methods used to pro duce PET images. The chapter starts out by reviewing the physics of positron emission and annihilation and explains how positron range and photon non colinearity in coincidence detection place certain limits on spatial resolution.