Molecular Genetic Medicine

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Molecular Medicine

Author : R.J. Trent
Publisher : Academic Press
ISBN 13 : 0123814510
Total Pages : 348 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Molecular Medicine by : R.J. Trent

Download or read book Molecular Medicine written by R.J. Trent and published by Academic Press. This book was released on 2012-08-17 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Medicine is the application of genetic or DNA-based knowledge to the modern practice of medicine. Molecular Medicine, 4e, provides contemporary insights into how the genetic revolution is influencing medical thinking and practice. The new edition includes recent changes in personalized medicine, new growth in omics and direct-to-consumer DNA testing, while focusing on advances in the Human Genome project and implications of the advances in clinical medicine. Graduate students, researchers, clinicians and allied health professionals will appreciate the background history and clinical application of up-to-date molecular advances. Extensively revised to incorporate the results of the Human Genome Project, it provides the latest developments in molecular medicine The only book in Molecular Medicine to reach its fourth edition Identifies current practice as well as future developments Presents extensive tables, well presented figures and resources for further understanding

An Introduction to Molecular Medicine and Gene Therapy

Author : Thomas F. Kresina
Publisher : John Wiley & Sons
ISBN 13 : 0471461040
Total Pages : 408 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis An Introduction to Molecular Medicine and Gene Therapy by : Thomas F. Kresina

Download or read book An Introduction to Molecular Medicine and Gene Therapy written by Thomas F. Kresina and published by John Wiley & Sons. This book was released on 2004-03-24 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Molecular Medicine and Gene Therapy Edited by Thomas F. Kresina, Ph.D. Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections - an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine and Gene Therapy: * Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations * Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases * Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter * Contains appendices on commercial implications and a review of the history of gene therapy This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine.

Molecular Genetic Medicine

Author : Theodore Friedmann
Publisher : Elsevier
ISBN 13 : 1483276058
Total Pages : 199 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Molecular Genetic Medicine by : Theodore Friedmann

Download or read book Molecular Genetic Medicine written by Theodore Friedmann and published by Elsevier. This book was released on 2013-10-22 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Genetic Medicine, Volume III, summarizes progress in several of the most important areas of modern molecular genetics and medicine. The book opens with a chapter on the birth and early development of the field of human gene therapy and the earliest conceptual and technical descriptions of the issues and opportunities in this new area of medicine. This is followed by separate chapters on the gene responsible for cystic fibrosis; interactions and genetic phenomena that accompany the progression of astrocytic tumors; and molecular biology of Alzheimer’s disease; and the search for the Huntington's disease gene and the role of genetic instability in this disease. The final chapter discusses the ways in which both the medical insurance and genetics industries will have to respond to changes in the power of genetic information and its ability to predict coronary vascular disease, cancer, neurological disease, and all the other common afflictions that constitute the bulk of their businesses.

Molecular Genetic Medicine

Author : Theodore Friedmann
Publisher : Elsevier
ISBN 13 : 1483261875
Total Pages : 248 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Molecular Genetic Medicine by : Theodore Friedmann

Download or read book Molecular Genetic Medicine written by Theodore Friedmann and published by Elsevier. This book was released on 2013-10-22 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Genetic Medicine, Volume II, summarizes progress in several of the most important areas of modern molecular genetics and medicine. The chapters deal with ancient and common genetic diseases, a new infectious disease that threatens to become a world-wide scourge for all of humanity, and two of the most important and still poorly understood causes of mental retardation. The common thread winding through these separate stories is the astounding illumination of all these disorders by modern molecular genetic studies. The book opens with a chapter on the history of the molecular approach to the thalassemias, among the most common and severe of all human genetic diseases. Separate chapters follow covering the history and current state of the fragile X syndrome; the mechanisms of hepatitis B viral gene expression, its relation to liver cancer, and its prevention; and molecular genetics of Down syndrome. Subsequent chapters deal with mammalian X chromosome inactivation; the use of the human hprt locus as a model system for analyzing mutation in human cells in vivo; and the regulatory genes and factors that govern virus replication of HIV-1.

Molecular Genetics Medicine

Author : Theodore Friedmann
Publisher : Academic Press
ISBN 13 : 1483295575
Total Pages : 203 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Molecular Genetics Medicine by : Theodore Friedmann

Download or read book Molecular Genetics Medicine written by Theodore Friedmann and published by Academic Press. This book was released on 2014-11-27 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuing to keep pace with progress in human molecular genetics, Volume 4 of Molecular Genetic Medicine reviews five new areas of critical importance. Chapter 1 reviews the molecular mechanisms that have beenunraveled in the pathogenesis of eye diseases. The second chapter explains the remarkable new principle if genomic imprinting, or epigenetic modification imposed by parental history. Chapter 3 describes the etiology of amyotrophic lateral sclerosis, or Lou Gehrig's Disease, as effected by superdioxide dismutase function and neuron degeneration. The fourth chapter covers the normal and aberrant functions of peroxisomes, now implicated in many diseases, most notably adrenoleukodystrophy, publicized widelyby the"cure"called Lorenzo's oil. The final chapter summarizes recombination techniques that permit functional new genetic material to be introduced into, and subsequently transmitted through, the germ line of mammalian cells. These amazing methods arehaving profound impacts on medicine and on concepts of the study of normal human development and disease. Presents technical and historical overviews of molecular biology applied to disease detection, diagnosis, and treatment Chronicles the continuing explosion of knowledge in molecular genetic medicine giving current approaches to understanding human illness Documents the revolution in human and molecular genetics leading to a new field of medicine

Molecular Genetic Medicine

Author : Theodore Friedmann
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (19 download)

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Book Synopsis Molecular Genetic Medicine by : Theodore Friedmann

Download or read book Molecular Genetic Medicine written by Theodore Friedmann and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Genetic Medicine

Author : Theodore Friedmann
Publisher : Elsevier
ISBN 13 : 1483262057
Total Pages : 255 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Molecular Genetic Medicine by : Theodore Friedmann

Download or read book Molecular Genetic Medicine written by Theodore Friedmann and published by Elsevier. This book was released on 2013-10-22 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Genetic Medicine, Volume I, provides an overview of the progress in several of the most important areas of modern molecular genetics and medicine. The aim is to present a technical and historical picture of the concept that it is through a thorough understanding of genetics of all kinds of human diseases, even infectious diseases, that effective treatments will finally come. The book opens with a discussion of the origins and development of the Human Genome Project. This is followed by separate chapters on the development of immune-deficient mice as models for human hematopoietic disease; the application of genetic techniques for testing identity and relatedness of persons; and advances in recombinant DNA technology and their applications in drug discovery. The final chapter discusses the impact of molecular biology and molecular evolution on debates about the origin of humans, and about the origins both of the characteristics that they share with other animals and of those that make humans unique.

Medical Genetics

Author : Lynn B. Jorde
Publisher :
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medical Genetics by : Lynn B. Jorde

Download or read book Medical Genetics written by Lynn B. Jorde and published by . This book was released on 2006 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Medical Genetics' offers up-to-date information on modern genetics. This comprehensive study includes the latest findings from genetic research and how that knowledge can be used in clinical practice.

Molecular Genetic Pathology

Author : Liang Cheng
Publisher : Springer Science & Business Media
ISBN 13 : 1597454052
Total Pages : 784 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Molecular Genetic Pathology by : Liang Cheng

Download or read book Molecular Genetic Pathology written by Liang Cheng and published by Springer Science & Business Media. This book was released on 2010-01-01 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a useful and up-to-date handbook containing information relevant to the clinical practice of molecular genetic pathology. It features organized, detailed text on specific molecular genetic techniques. The volume provides a unique reference for the practicing pathologist and medical geneticist, as well as a review book for residents and fellows in training in pathology, medical genetics and molecular genetic pathology.

Advances in Genetics

Author :
Publisher : Academic Press
ISBN 13 : 9780080568195
Total Pages : 322 pages
Book Rating : 4.5/5 (681 download)

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Book Synopsis Advances in Genetics by :

Download or read book Advances in Genetics written by and published by Academic Press. This book was released on 1995-06-23 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 32 of Advances in Genetics: Incorporating Molecular Genetic Medicine focuses on important and fast moving subjects in modern human genetics and medicine. This volume also marks the new collaboration with Associate Editors Dr. Theodore Friedmann and Dr. Francesco Giannelli. Chapter 1 considers the potential effectiveness and consequences of gene therapy on subjects over time. Chapter 2 discusses recent research on Gaucher's disease, the first disorder to demonstrate the clinical benefits of enzyme replacement therapy. Chapter 3 describes current findings on diabetes, a disease difficult to conquer due to its variety and its genetic and environmental causes. The major forms of hemophilia and the need for alternative therapies are discussed in Chapter 4. Chapter 5 presents hypercholesterolemia as a model for understanding the causes and treatments of human diseases on a molecular level. Chapter 6 probes the basic genetic defects behind phenylketonuria, as well as the possibilities for genetic correction. Chapter 7 covers the fascinating terminal structures of human chromosomes. In the Foreword to Volume 32, Drs. Friedmann and Giannelli suggest: "Progress toward a thorough characterization of the human genome is stunningly rapid and exceeding many of its earliest expectations. Disease-related genes will be falling from the skies faster than we can understand them, and mechanisms responsible for the pathogenesis of disease will be illuminated more quickly and readily than ever before. "With comprehensive and timely reviews, Advances in Genetics incorporating Molecular Genetic Medicine offers with every volume further insight into this expanding field of medicine, supplementing the continued expert coverage of all other areas of genetics pioneered by Advances in Genetics. Key Features * Presents technical and historical overviews of molecular biology applied to disease detection, diagnosis, and treatment * Chronicles the continuing explosion of knowledge in molecular genetic medicine by highlighting current approaches to understanding human illness * Documents the revolution in human and molecular genetics leading to a new field of medicine * Volume 32 marks new collaboration with Associate Editors Dr. Theodore Friedmann and Dr. Francesco Giannelli

Molecular Diagnosis of Genetic Diseases

Author : Rob Elles
Publisher : Springer Science & Business Media
ISBN 13 : 1592594328
Total Pages : 392 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Molecular Diagnosis of Genetic Diseases by : Rob Elles

Download or read book Molecular Diagnosis of Genetic Diseases written by Rob Elles and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This completely revised and updated second edition to integrates the many new technologies and insights now available for the diagnosis of genetic diseases. The authors use such methodologies as PCR optimization dosage analysis, mutation scanning, and quantitative fluorescent PCR for aneuploidy analysis, Neurofibromatosis type 1, and Duchenne muscular dystrophy. These largely generic methodologies may be adapted to most genetic conditions for which a molecular diagnosis is relevant, no matter how frequent or rare their incidence. Molecular Diagnosis of Genetic Diseases, Second Edition offers diagnostic molecular geneticists a unique opportunity to sharpen their scientific skills in the design of assays, their execution, and their interpretation.

Molecular Genetics and Personalized Medicine

Author : D. Hunter Best
Publisher : Springer Science & Business Media
ISBN 13 : 1617795305
Total Pages : 248 pages
Book Rating : 4.6/5 (177 download)

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Book Synopsis Molecular Genetics and Personalized Medicine by : D. Hunter Best

Download or read book Molecular Genetics and Personalized Medicine written by D. Hunter Best and published by Springer Science & Business Media. This book was released on 2012-01-05 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic testing has become commonplace, and clinicians are frequently able to use knowledge of an individual’s specific genetic differences to guide their course of action. Molecular Genetics and Personalized Medicine highlights developments that have been made in the field of molecular genetics and how they have been applied clinically. It will serve as a useful reference for physicians hoping to better understand the role of molecular medicine in clinical practice. In addition, it should also prove to be an invaluable resource for the basic scientist that wants to better understand how advances in the laboratory are being moved from the bench to the bedside. All chapters are written by experts in their fields and include the most up to date medical information. The authors simplify complex genetic concepts and focus on practical patient related issues. The book will be of great value to pathologists, hematologists/oncologists, clinical geneticists, high-risk obstetricians, general practitioners, and physicians in all other medical specialties who utilize genetic testing to direct therapy.

Genes in Medicine

Author : I. Rasko
Publisher : Springer Science & Business Media
ISBN 13 : 9780412373404
Total Pages : 436 pages
Book Rating : 4.3/5 (734 download)

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Book Synopsis Genes in Medicine by : I. Rasko

Download or read book Genes in Medicine written by I. Rasko and published by Springer Science & Business Media. This book was released on 1994-09-30 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This stimulating book bridges the gap between molecular biology and human genetics. Specifically written for medical students and human geneticists, it is a valuable guide to a rapidly moving field.

Molecular Genetic Pathology

Author : Liang Cheng
Publisher : Springer
ISBN 13 : 9781461447993
Total Pages : 1136 pages
Book Rating : 4.4/5 (479 download)

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Book Synopsis Molecular Genetic Pathology by : Liang Cheng

Download or read book Molecular Genetic Pathology written by Liang Cheng and published by Springer. This book was released on 2013-03-05 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Genetic Pathology, Second Edition presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Fully updated in each area and expanded to include identification of new infectious agents (H1N1), new diagnostic biomarkers and biomarkers for targeted cancer therapy. This edition is also expanded to include the many new technologies that have become available in the past few years such as microarray (AmpliChip) and high throughput deep sequencing, which will certainly change the clinical practice of molecular genetic pathology. Part I examines the clinical aspects of molecular biology and technology, genomics. Poharmacogenomics and proteomics, while Part II covers the clinically relevant information of medical genetics, hematology, transfusion medicine, oncology, and forensic pathology. Supplemented with many useful figures and presented in a helpful bullet-point format, Molecular Genetic Pathology, Second Edition provides a unique reference for practicing pathologists, oncologists, internists, and medical genetisists. Furthermore, a book with concise overview of the field and highlights of clinical applications will certainly help those trainees, including pathology residents, genetics residents, molecular pathology fellows, internists, hematology/oncology fellows, and medical technologists in preparing for their board examination/certification.

Molecular Genetics in Medicine

Author : D.F. Roberts
Publisher : Springer
ISBN 13 : 134910874X
Total Pages : 258 pages
Book Rating : 4.3/5 (491 download)

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Book Synopsis Molecular Genetics in Medicine by : D.F. Roberts

Download or read book Molecular Genetics in Medicine written by D.F. Roberts and published by Springer. This book was released on 1991-06-18 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: A report of the proceedings of the Galton Institute's symposium which explored ethical, legal, political and psychological problems arising within advances in molecular genetics. It concentrates on the applications of molecular genetic techniques in clinical genetics.

Genetics and Genomics in Medicine

Author : Tom Strachan
Publisher : Taylor & Francis
ISBN 13 : 1317594304
Total Pages : 545 pages
Book Rating : 4.3/5 (175 download)

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Book Synopsis Genetics and Genomics in Medicine by : Tom Strachan

Download or read book Genetics and Genomics in Medicine written by Tom Strachan and published by Taylor & Francis. This book was released on 2014-06-02 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics and Genomics in Medicine is a new textbook written for undergraduate students, graduate students, and medical researchers that explains the science behind the uses of genetics and genomics in medicine today. Rather than focusing narrowly on rare inherited and chromosomal disorders, it is a comprehensive and integrated account of how geneti

Thompson & Thompson Genetics in Medicine

Author : Robert L. Nussbaum
Publisher :
ISBN 13 : 9788131243145
Total Pages : 532 pages
Book Rating : 4.2/5 (431 download)

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Book Synopsis Thompson & Thompson Genetics in Medicine by : Robert L. Nussbaum

Download or read book Thompson & Thompson Genetics in Medicine written by Robert L. Nussbaum and published by . This book was released on 2015-08-16 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated to reflect the newest changes in genetics, Thompson & Thompson's Genetics in Medicine returns as one of the most favored texts in this fascinating and rapidly evolving field. By integrating the classic principles of human genetics with modern molecular genetics, this medical reference book utilizes a variety of learning tools to help you understand a wide range of genetic disorders. Acquire the state-of-the-art knowledge you need on the latest advances in molecular diagnostics, the Human Genome Project, pharmacogenetics, and bio-informatics. Better understand the relationship between basic genetics and clinical medicine with a variety of clinical case studies. Recognize a wide range of genetic disorders with visual guidance from more than 240 dynamic illustrations and high-quality photos.