Molecular Biology of Rifomycin

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Author :
Publisher : Ardent Media
ISBN 13 : 9780842270892
Total Pages : 220 pages
Book Rating : 4.2/5 (78 download)

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Book Synopsis Molecular Biology of Rifomycin by : Henry A. Erlich

Download or read book Molecular Biology of Rifomycin written by Henry A. Erlich and published by Ardent Media. This book was released on 1973 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Antibiotic Resistome

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Publisher : Wiley
ISBN 13 : 9781118376737
Total Pages : 384 pages
Book Rating : 4.3/5 (767 download)

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Book Synopsis The Antibiotic Resistome by : Gerry Wright

Download or read book The Antibiotic Resistome written by Gerry Wright and published by Wiley. This book was released on 2016-08-22 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Synthesis of Essential Drugs

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Publisher : Elsevier
ISBN 13 : 008046212X
Total Pages : 635 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Synthesis of Essential Drugs by : Ruben Vardanyan

Download or read book Synthesis of Essential Drugs written by Ruben Vardanyan and published by Elsevier. This book was released on 2006-03-10 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO's Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types* Includes synonyms* Includes over 2300 references

Molecular Biology and Pathogenicity of Mycoplasmas

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Publisher : Springer Science & Business Media
ISBN 13 : 0306476061
Total Pages : 574 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Molecular Biology and Pathogenicity of Mycoplasmas by : Shmuel Razin

Download or read book Molecular Biology and Pathogenicity of Mycoplasmas written by Shmuel Razin and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: was the result of the efforts of Robert Cleverdon. The rapidly developing discipline of molecular biology and the rapidly expanding knowledge of the PPLO were brought together at this meeting. In addition to the PPLO specialists, the conference invited Julius Marmur to compare PPLO DNA to DNA of other organisms; David Garfinkel, who was one of the first to develop computer models of metabolism; Cyrus Levinthal to talk about coding; and Henry Quastler to discuss information theory constraints on very small cells. The conference was an announcement of the role of PPLO in the fundamental understanding of molecular biology. Looking back 40-some years to the Connecticut meeting, it was a rather bold enterprise. The meeting was international and inter-disciplinary and began a series of important collaborations with influences resonating down to the present. If I may be allowed a personal remark, it was where I first met Shmuel Razin, who has been a leading figure in the emerging mycoplasma research and a good friend. This present volume is in some ways the fulfillment of the promise of that early meeting. It is an example of the collaborative work of scientists in building an understanding of fundamental aspects of biology.

Disease Control Priorities, Third Edition (Volume 6)

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Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Nanostructures for Antimicrobial Therapy

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Publisher : Elsevier
ISBN 13 : 0323461514
Total Pages : 724 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Nanostructures for Antimicrobial Therapy by : Anton Ficai

Download or read book Nanostructures for Antimicrobial Therapy written by Anton Ficai and published by Elsevier. This book was released on 2017-05-29 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. - Shows how nanoantibiotics can be used to more effectively treat disease - Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs - Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Genetics and Biochemistry of Antibiotic Production

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Author :
Publisher : Butterworth-Heinemann
ISBN 13 :
Total Pages : 714 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genetics and Biochemistry of Antibiotic Production by : L. Vining

Download or read book Genetics and Biochemistry of Antibiotic Production written by L. Vining and published by Butterworth-Heinemann. This book was released on 1995 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: * Emphasizes the molecular genetics of antibiotic production * Provides the latest information on the organization of genes encoding the biosynthetic pathway * Explores the mechanisms governing their expression and regulation * Examines the role of resistance genes in protecting organisms from their own lethal productsGenetics and Biochemistry of Antibiotic Production brings together the most up-to-date information on the genetic and biochemical mechanisms involved in antibiotic production. A collection of internationally recognized authors provide the latest information on the organization, function and regulation of genes responsible for antibiotic synthesis in a range of bacteria. This unique book groups antibiotics according to their biosynthetic affiliation, providing a background into evolutionaryrelationships while raising intriguing questions about the raison d'etre of antibiotics in nature.

Antimicrobial Chemotherapy

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Publisher : OUP Oxford
ISBN 13 : 0191628654
Total Pages : 409 pages
Book Rating : 4.1/5 (916 download)

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Book Synopsis Antimicrobial Chemotherapy by : Roger Finch

Download or read book Antimicrobial Chemotherapy written by Roger Finch and published by OUP Oxford. This book was released on 2012-01-05 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the need for a thorough understanding of the advantages and risks associated with specific antibiotic choices. This sixth edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs. This new edition is updated to include the most recently licensed agents, notably in the treatment of viral infections including HIV/AIDS, and contains new guidance on prescribing practice and infection control practices that limit the development and spread of resistant organisms.

Virulence Mechanisms of Bacterial Pathogens

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Publisher : John Wiley & Sons
ISBN 13 : 1683673204
Total Pages : 1378 pages
Book Rating : 4.6/5 (836 download)

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Book Synopsis Virulence Mechanisms of Bacterial Pathogens by : Indira T. Kudva

Download or read book Virulence Mechanisms of Bacterial Pathogens written by Indira T. Kudva and published by John Wiley & Sons. This book was released on 2016-06-01 with total page 1378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ground-breaking overview of an enduring topic Despite the use of antibiotics, bacterial diseases continue to be a critical issue in public health, and bacterial pathogenesis remains a tantalizing problem for research microbiologists. This new edition of Virulence Mechanisms of Bacterial Pathogens broadly covers the knowledge base surrounding this topic and presents recently unraveled bacterial virulence strategies and cutting-edge therapies. A team of editors, led by USDA scientist Indira Kudva, compiled perspectives from experts to explain the wide variety of mechanisms through which bacterial pathogens cause disease: the host interface, host cell enslavement, and bacterial communication, secretion, defenses, and persistence. A collection of reviews on targeted therapies rounds out the seven sections of this unique book. The new edition provides insights into some of the most recent advances in the area of bacterial pathogenesis, including how metabolism shapes the host-pathogen interface interactions across species and genera mechanisms of the secretion systems evasion, survival, and persistence mechanisms new therapies targeting various adaptive and virulence mechanisms of bacterial pathogens Written to promote discussion, extrapolation, exploration, and multidimensional thinking, Virulence Mechanisms of Bacterial Pathogens serves as a textbook for graduate courses on bacterial pathogenesis and a resource for specialists in bacterial pathogenicity, such as molecular biologists, physician scientists, infectious disease clinicians, dental scientists, veterinarians, molecular biologists, industry researchers, and technicians.

Lasso Peptides

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Publisher : Springer
ISBN 13 : 1493910108
Total Pages : 113 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Lasso Peptides by : Yanyan Li

Download or read book Lasso Peptides written by Yanyan Li and published by Springer. This book was released on 2014-10-21 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lasso peptides form a growing family of fascinating ribosomally-synthesized and post-translationally modified peptides produced by bacteria. They contain 15 to 24 residues and share a unique interlocked topology that involves an N-terminal 7 to 9-residue macrolactam ring where the C-terminal tail is threaded and irreversibly trapped. The ring results from the condensation of the N-terminal amino group with a side-chain carboxylate of a glutamate at position 8 or 9, or an aspartate at position 7, 8 or 9. The trapping of the tail involves bulky amino acids located in the tail below and above the ring and/or disulfide bridges connecting the ring and the tail. Lasso peptides are subdivided into three subtypes depending on the absence (class II) or presence of one (class III) or two (class I) disulfide bridges. The lasso topology results in highly compact structures that give to lasso peptides an extraordinary stability towards both protease degradation and denaturing conditions. Lasso peptides are generally receptor antagonists, enzyme inhibitors and/or antibacterial or antiviral (anti-HIV) agents. The lasso scaffold and the associated biological activities shown by lasso peptides on different key targets make them promising molecules with high therapeutic potential. Their application in drug design has been exemplified by the development of an integrin antagonist based on a lasso peptide scaffold. The biosynthesis machinery of lasso peptides is therefore of high biotechnological interest, especially since such highly compact and stable structures have to date revealed inaccessible by peptide synthesis. Lasso peptides are produced from a linear precursor LasA, which undergoes a maturation process involving several steps, in particular cleavage of the leader peptide and cyclization. The post-translational modifications are ensured by a dedicated enzymatic machinery, which is composed of an ATP-dependent cysteine protease (LasB) and a lactam synthetase (LasC) that form an enzymatic complex called lasso synthetase. Microcin J25, produced by Escherichia coli AY25, is the archetype of lasso peptides and the most extensively studied. To date only around forty lasso peptides have been isolated, but genome mining approaches have revealed that they are widely distributed among Proteobacteria and Actinobacteria, particularly in Streptomyces, making available a rich resource of novel lasso peptides and enzyme machineries towards lasso topologies.

Mechanisms of antibiotic resistance

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889195260
Total Pages : 226 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Mechanisms of antibiotic resistance by : Jun Lin

Download or read book Mechanisms of antibiotic resistance written by Jun Lin and published by Frontiers Media SA. This book was released on 2015-06-01 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.

Bioimaging

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Publisher : Jones & Bartlett Publishers
ISBN 13 : 0763738743
Total Pages : 468 pages
Book Rating : 4.7/5 (637 download)

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Book Synopsis Bioimaging by : Douglas E. Chandler

Download or read book Bioimaging written by Douglas E. Chandler and published by Jones & Bartlett Publishers. This book was released on 2009 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Development Of Microscopy Revolutionized The World Of Cell And Molecular Biology As We Once Knew It And Will Continue To Play An Important Role In Future Discoveries. Bioimaging: Current Concepts In Light And Electron Microscopy Is The Optimal Text For Any Undergraduate Or Graduate Bioimaging Course, And Will Serve As An Important Reference Tool For The Research Scientist. This Unique Text Covers, In Great Depth, Both Light And Electron Microscopy, As Well As Other Structure And Imaging Techniques Like X-Ray Crystallography And Atomic Force Microscopy. Written In A User-Friendly Style And Covering A Broad Range Of Topics, Bioimaging Describes The State-Of-The-Art Technologies That Have Powered The Field To The Forefront Of Cellular And Molecular Biological Research.

Oxford Handbook of Infectious Diseases and Microbiology

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Publisher : Oxford University Press
ISBN 13 : 019105920X
Total Pages : 914 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Oxford Handbook of Infectious Diseases and Microbiology by : Estée Török

Download or read book Oxford Handbook of Infectious Diseases and Microbiology written by Estée Török and published by Oxford University Press. This book was released on 2016-12-06 with total page 914 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully reviewed and revised for its second edition, the Oxford Handbook of Infectious Diseases and Microbiology maintains its position as the must-have guide to all aspects of infectious diseases and microbiology. Reflecting the current approach to joint postgraduate training programmes, the handbook takes an integrated approach to both subjects. It covers the basic principles of bacteriology and virology, along with specific guidance on individual diseases and conditions, all in the accessible Oxford Handbook style. Now including new topics on important subjects such as microbiology specimen collection, commonly used media, molecular diagnostics, and antimicrobials in pregnancy, as well as incorporating new guidelines from WHO, NICE, and BASHH among others, this handbook ensures that the informaiton you need is accessible, clear, and easy-to-understand. Practical and comprehensive, this handbook includes coverage of National Frameworks and current legislation, together with information on topical issues such as bioterrorism and preventative medicine. Fully reviewed by specialist senior readers, and with useful links to up-to-date clinical information and online resources, this is an important addition to the Oxford Handbook Series.

Handbook of Pharmaceutical Analysis by HPLC

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Author :
Publisher : Elsevier
ISBN 13 : 0080455182
Total Pages : 679 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Handbook of Pharmaceutical Analysis by HPLC by : Satinder Ahuja

Download or read book Handbook of Pharmaceutical Analysis by HPLC written by Satinder Ahuja and published by Elsevier. This book was released on 2005-02-09 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: High pressure liquid chromatography–frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening). A complete reference guide to HPLC Describes best practices in HPLC and offers 'tricks of the trade' in HPLC operation and method development Reviews key HPLC pharmaceutical applications and highlights currents trends in HPLC ancillary techniques, sample preparations, and data handling

Antibiotic and Chemotherapy

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Publisher :
ISBN 13 : 9780443071294
Total Pages : 0 pages
Book Rating : 4.0/5 (712 download)

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Book Synopsis Antibiotic and Chemotherapy by : Roger G. Finch

Download or read book Antibiotic and Chemotherapy written by Roger G. Finch and published by . This book was released on 2003 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The completely revised and updated New Edition of this respected resource presents globally-relevant coverage of all types of antimicrobial agents used in human medicine, providing authoritative guidance on the principles and practice of antimicrobial chemotherapy. In addition to full coverage of every commonly used antibiotic agent, it includes complete coverage of all antiviral, antiprotozoan and anthelminthic agents. And, its unique 3-part structure makes it easy to locate information: Part I covers general aspects of treatment; Part II reviews every agent, including antimicrobial activity, pharmacokinetics, clinical use, and available preparations; Part III details the treatment of particular infections. Discusses the increasing problem of multi-drug resistance and the wide range of new antiviral therapies now available for the treatment of HIV and other viral infections. Reviews all of the new antimicrobial agents in detail. Features more clinically focused sections on Pharmacokinetics. Details new antifungal therapies, including voriconazole, liposomal, and amphotericin B. Presents new tables on major drug interactions, placental transfer, and concentrations of agents in breast milk. Features new sections on liver failure, drug development and licensing, and the implications of xenotransplantation. Presents expanded coverage of Quinolone as well as new antimalarial combination therapies. Offers cross-references to key web sites, for up-to-date information on treatment and drug resistance.

Dictionary of Microbiology & Molecular Biology

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Publisher :
ISBN 13 : 9780470056998
Total Pages : 908 pages
Book Rating : 4.0/5 (569 download)

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Book Synopsis Dictionary of Microbiology & Molecular Biology by : Paul Singleton

Download or read book Dictionary of Microbiology & Molecular Biology written by Paul Singleton and published by . This book was released on 2007-11-12 with total page 908 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Third, Revised Edition of a unique, encyclopaedic reference work covers the whole field of pure and applied microbiology and microbial molecular biology, from A to Zythia.

The Effects on Human Health of Subtherapeutic Use of Antimicrobials in Animal Feeds

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Author :
Publisher : National Academies Press
ISBN 13 : 0309030447
Total Pages : 393 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis The Effects on Human Health of Subtherapeutic Use of Antimicrobials in Animal Feeds by : National Research Council

Download or read book The Effects on Human Health of Subtherapeutic Use of Antimicrobials in Animal Feeds written by National Research Council and published by National Academies Press. This book was released on 1980-02-01 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: