Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Download Molecular Biology And Pharmacology Of Cyclic Nucleotides full books in PDF, epub, and Kindle. Read online Molecular Biology And Pharmacology Of Cyclic Nucleotides ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author : Giancarlo Folco
Publisher : North-Holland
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.3/5 (91 download)
Download or read book Molecular Biology and Pharmacology of Cyclic Nucleotides written by Giancarlo Folco and published by North-Holland. This book was released on 1978 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : 110
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (144 download)
Download or read book Molecular Biology and Pharmacology of Cyclic Nucleotides written by 110 and published by . This book was released on 1977 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 24 pages
Book Rating : 4.:/5 (3 download)
Download or read book ICRDB Cancergram written by and published by . This book was released on 1978 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Xiaodong Cheng
Publisher : CRC Press
ISBN 13 : 1482235579
Total Pages : 282 pages
Book Rating : 4.4/5 (822 download)
Download or read book Cyclic Nucleotide Signaling written by Xiaodong Cheng and published by CRC Press. This book was released on 2015-05-07 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Showcasing the recent progresses of the field, Cyclic Nucleotide Signaling covers the major tools and methodologies used in various areas of research. The majority of the chapters are protocol oriented, with the goal of providing clear directions for laboratory use. Students and investigators new to the field will find this book particularly inform
Author : Giancarlo Folco
Publisher :
ISBN 13 :
Total Pages : 340 pages
Book Rating : 4.:/5 (486 download)
Download or read book Molecular Biology and Pharmacology of Cyclic Nucleotìdes written by Giancarlo Folco and published by . This book was released on 1978 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (141 download)
Download or read book Molecular Biology and Pharmacology of Cyclic Nucleotides written by and published by . This book was released on 1978 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J. A. Nathanson
Publisher : Springer Science & Business Media
ISBN 13 : 3642681115
Total Pages : 570 pages
Book Rating : 4.6/5 (426 download)
Download or read book Cyclic Nucleotides written by J. A. Nathanson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the present volume, the first of two on the pharmacology, biochemistry, and physiology of cyclic nucleotides, is to provide a comprehensive and up-to-date anthology on the nature and role of these important chemical regulators. Each of the chapters is the work of internationally known researchers who present a lucid and detailed review of their subject and not merely a single laboratory's viewpoint. The chapters emphasize critical assessments of the field rather than mere listings of experimental findings. By so doing, the contributors present the role of cyclic nucleotides in relationship to other intracellular regulators. Each chapter begins with a detailed summary to allow the reader to obtain a rapid overview of subsequent material. In addition, there are extensive bibliographies and a detailed subject index. Wherever pertinent, the chapters contain sections on drug mechanisms, physiological relevance, and disease processes. The Volume is divided into two sections, each beginning with an overview written by Professors T. W. RALL and P. GREENGARD, respectively. The first section focuses on the detailed pharmacology and chemistry of cyclic nucleotides, including their formation, degradation, measurement, and interaction with various modulatory agents, such as receptors and calcium. The second section is concerned with the biochemistry of protein phosphorylation, a process which appears to be one of the most important mechanisms for the intracellular expression of cyclic nucleotide action in eukaryotic cells.
Author : Roland Seifert
Publisher : Springer
ISBN 13 : 3319526731
Total Pages : 379 pages
Book Rating : 4.3/5 (195 download)
Download or read book Non-canonical Cyclic Nucleotides written by Roland Seifert and published by Springer. This book was released on 2017-04-28 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cyclic purine nucleotides 3’,5’-cAMP and 3’,5’-cGMP are well-established second messengers. cGMP has recently been covered in a volume of the Handbook of Experimental Pharmacology (volume 191). In addition to 3’,5’-cAMP and 3’,5’-cGMP, so-called non-canonical cyclic nucleotides exist. These comprise the cyclic pyrimidine nucleotides 3’,5’-cCMP and 3’,5’-cUMP, the purine nucleotide 3’,5’-cIMP, the 2’,3’-nucleoside monophosphates and cyclic dinucleotides. In this volume of the Handbook of Pharmacology, word-leading experts in the field summarize our current knowledge on these non-canonical cyclic nucleotides, discuss open questions, future research directions and the pharmacotherapeutic implications. Special emphasis will be given to the emerging roles of 3’,5’-cCMP and 3’,5’-cUMP as second messengers with regard to generators, effectors, biological functions, inactivation and bacterial toxins. The role of 3’,5’-cIMP as potential second messenger will also be critically discussed. Furthermore, we will consider transport of cyclic nucleotides and their potential role as first messengers. The role of the cyclic dinucleotide cGAMP in the immune system will covered, too. Lastly, the book will present important methodological aspects ranging from mass-spectrometric methods for cyclic nucleotide detection to the synthesis of nucleotide analogs as experimental tools and holistic methods for analysis of cyclic nucleotide effects.
Author : Giancarlo Folco
Publisher :
ISBN 13 :
Total Pages : 340 pages
Book Rating : 4.:/5 (989 download)
Download or read book Cyclic Nucleotides written by Giancarlo Folco and published by . This book was released on 1978 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : John Daly
Publisher : Springer Science & Business Media
ISBN 13 : 1461341272
Total Pages : 408 pages
Book Rating : 4.4/5 (613 download)
Download or read book Cyclic Nucleotides in the Nervous System written by John Daly and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The elucidation of the cellular and molecular bases underlying the inte grated function of the central nervous system, both in disease and in health, must ultimately come from the combined efforts of scientists from many disciplines, including biology, chemistry, histology, pathology, physiology, pharmacology, and psychology. Communication between scientists from these various disciplines-vital to the advancement of our understanding of the function of the nervous system-has become more and more difficult in recent years. Both increasing specialization and the incredible increases in publications pertinent to brain research in a wide spectrum of journals, in symposium volumes, in monographs, in abstracts, and in reviews contrib ute to the problems of cross-communication and even of communication within a scientific discipline. Research on the significance of cyclic nucleo tides to the function of nervous systems is particularly illustrative of the communication problem. Since the initial publications by Sutherland, Rall, and Butcher in the late fifties and early sixties on high levels of adenylate cyclase, phosphodiesterases, and cyclic AMP in brain, the ensuing litera ture of this field has expanded exponentially. At the present time, from five to ten publications relevant to cyclic nucleotides and the nervous system appear each week. Indeed, these are minimal numbers based mainly on examination of literature titles and key index words. Many articles concerned with some aspect of central function contain, buried within their text, experiments with or related to cyclic nucleotides.
Author : J.C. Stoclet
Publisher : Elsevier
ISBN 13 : 1483188574
Total Pages : 341 pages
Book Rating : 4.4/5 (831 download)
Download or read book Ions-Cyclic Nucleotides-Cholinergy written by J.C. Stoclet and published by Elsevier. This book was released on 2013-10-22 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Pharmacology and Therapeutics, Volume 3: Ions – Cyclic Nucleotides – Cholinergy covers the proceedings of the Seventh International Congress of Pharmacology, held in Paris in 1978. This book mainly focuses on studying ions, cyclic nucleotides, and cholinergy. Specifically, this text discusses the pharmacology of calcium homeostasis and presents lectures given in the symposium. The role of cyclic nucleotides in the regulation of muscular tissue functions and the evaluation of cyclic AMP and cyclic GMP are also looked into. This text presents in its latter part papers on chemical structure and cholinergic activity. This volume will be valuable to students and experts in the field of pharmacology, therapeutics, and related fields.
Author : John Dickenson
Publisher : John Wiley & Sons
ISBN 13 : 1118451953
Total Pages : 675 pages
Book Rating : 4.1/5 (184 download)
Download or read book Molecular Pharmacology written by John Dickenson and published by John Wiley & Sons. This book was released on 2012-11-30 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of ‘trial and error’ drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments. Providing an invaluable resource for advanced under-graduate and MSc/PhD students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy, pharmacogenomics and looks at the role of calcium in the cell. Current - focuses on cutting edge techniques and approaches, including new methods to quantify biological activities in different systems and ways to interpret and understand pharmacological data. Cutting Edge - highlights advances in pharmacogenomics and explores how an individual’s genetic makeup influences their response to therapeutic drugs and the potential for harmful side effects. Applied - includes numerous, real-world examples and a detailed case-study based chapter which looks at current and possible future treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect. Accessible - contains a comprehensive glossary, suggestions for further reading at the end of each chapter and an associated website that provides a complete set of figures from within the book.
Author : Joe Beavo
Publisher :
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.3/5 (91 download)
Download or read book Cyclic Nucleotide Phosphodiesterases written by Joe Beavo and published by . This book was released on 1990-11-30 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Second volume in a series addressing topical areas important to the understanding of the control of biological processes. This volume focuses on the structure and molecular biology of isoenzymes and their role in signal transduction processes necessary for co-ordinating cellular functioning.
Author : G Robison
Publisher : Elsevier
ISBN 13 : 0323146481
Total Pages : 544 pages
Book Rating : 4.3/5 (231 download)
Download or read book Cyclic AMP written by G Robison and published by Elsevier. This book was released on 2012-12-02 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cyclic AMP provides information pertinent to cyclic adenosine 3',5'-monophosphate (AMP), a regulatory agent that controls the rate of a number of cellular processes. This book discusses the heat-stable factor mediating the action of glucagon and epinephrine on the activation of liver phosphorylase. Organized into 12 chapters, this book starts with an overview of the biological role of cyclic AMP, which is extended from a relatively simple role in liver glycogenolysis to a significant regulatory agent in most mammalian tissues. This text then discusses the development that led to the discovery of the heat-stable factor from investigations with cyclic nucleotides. Other chapters explore the chemical agents, which are released from one group of cells and travel via the bloodstream to affect one or more different groups of cells. The final chapter discusses the role of cyclic AMP to mammalian physiology, with emphasis on the many possible defects that may lead to human disease. This book is a valuable resource for graduate students and clinical investigators involved in biological and biomedical sciences.
Author : Samuel J. Strada
Publisher :
ISBN 13 :
Total Pages : 429 pages
Book Rating : 4.:/5 (636 download)
Download or read book The Biology of Cyclic Nucleotide Phosphodiesterases written by Samuel J. Strada and published by . This book was released on 1992 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Joseph A. Beavo
Publisher : CRC Press
ISBN 13 : 1420020846
Total Pages : 728 pages
Book Rating : 4.4/5 (2 download)
Download or read book Cyclic Nucleotide Phosphodiesterases in Health and Disease written by Joseph A. Beavo and published by CRC Press. This book was released on 2006-12-05 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the last major compendium dedicated to cyclic nucleotide phosphodiesterases (PDEs) was published over 15 years ago, an enormous amount of progress has occurred in the field. There is great need for a centralized source for key information in this burgeoning and therapeutically important area of medical research. Cyclic Nucleotide Phosph
Author :
Publisher : Academic Press
ISBN 13 : 008058117X
Total Pages : 354 pages
Book Rating : 4.0/5 (85 download)
Download or read book Cyclic GMP: Synthesis, Metabolism, and Function written by and published by Academic Press. This book was released on 1994-05-18 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is dedicated to the topic of cyclic GMP. Chapters include discussions on the guanylyl cyclase and phosphodiesterase isoenzyme families for cyclic GMP synthesis and hydrolysis, cyclic GMP-dependent protein kinases, and various hormones and ligands that regulate cyclic GMP formation and/or metabolism. Several chapters also deal with some of the effects of cyclic GMP on other second messengers such as calcium ion transport and smooth muscle relaxation. Some clinical studies with cyclic GMP and atrial natriuretic peptide are also discussed. The last chapter raises many important questions in the field that remain to be addressed. Isoforms of guanylyl cyclase and phosphodiesterase isoenzyme families for cyclic GMP synthesis and hydrolysis Cyclic GMP-dependent protein kinase Hormones and ligands that regulate GMP formation and/or metabolism Effects of cyclic GMP on other second messengers and some functions such as smooth muscle relaxation and ion transport Clinical studies with cyclic GMP and atrial natriuretic peptide Important questions and experiments for the future
