Molecular And Subcellular Cardiology

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Molecular and Subcellular Cardiology

Author : S. Sideman
Publisher : Springer Science & Business Media
ISBN 13 : 1461518938
Total Pages : 351 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Molecular and Subcellular Cardiology by : S. Sideman

Download or read book Molecular and Subcellular Cardiology written by S. Sideman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Henry Goldberg Workshops were set up to address the following goals: (1) To foster interdisciplinary interaction between scientists and cardiologists, identify missing links, and catalyze new ideas. (2) To relate basic microscale phenomena to the global, clinically manifested cardiac function. (3) To relate conceptual modeling and quantitative analysis to experimental and clinical data. (4) To encourage international cooperation so as to disperse medical and technological knowhow and lead to better understanding of the cardiac system. The first Henry Goldberg Workshop, held in Haifa in 1984, introduced the concept of interaction between cardiac mechanics, electrical activation, perfusion, and metabolism, emphasizing imaging in the clinical environment. The second Workshop, in 1985, discussed the same parameters with a slant towards the control aspects. The third Goldberg Workshop, held in the USA at Rutgers University in 1986, highlighted the transformation of the microscale activation phenomena to macroscale activity and performance, relating electrophysiology, energy metabolism, and cardiac mechanics. The fourth Goldberg Workshop, in 1987, continued the effort to elucidate the interactions among the various parameters affecting cardiac performance, with emphasis on the ischemic heart. The fifth Workshop, held in Cambridge, UK, in 1988, dwelt on the effects of inhomogeneity of the cardiac muscle on its performance in health and disease. The sixth Workshop highlighted the role of new modem imaging techniques, that allow us to gain more insight into local and global cardiac performance in cardiac research and clinical practice.

Analytical and Quantitative Cardiology

Author : S. Sideman
Publisher : Springer Science & Business Media
ISBN 13 : 1461559596
Total Pages : 362 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Analytical and Quantitative Cardiology by : S. Sideman

Download or read book Analytical and Quantitative Cardiology written by S. Sideman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tenth Henry Goldberg Workshop is an excellent occasion to recall our goals and celebrate some of our humble achievements. Vision and love of our fellow man are combined here to: 1) Foster interdisciplinary interaction between leading world scientists and clinical cardiologists so as to identify missing knowledge and catalyze new research ideas; 2) relate basic microscale, molecular and subcellular phenomena to the global clinically manifested cardiac performance; 3) apply conceptual modelling and quantitative analysis to better explore, describe, and understand cardiac physiology; 4) interpret available clinical data and design new revealing experiments; and 5) enhance international cooperation in the endless search for the secrets of life and their implication on cardiac pathophysiology. The first Goldberg Workshop, held in Haifa, in 1984, explored the interaction of mechanics, electrical activation, perfusion and metabolism, emphasizing imaging in the clinical environment. The second Workshop, in 1985, discussed the same parameters with a slant towards the control aspects. The third Goldberg Workshop, held in the USA at Rutgers University, in 1986, highlighted the transformation of the microscale activation phenomena to macro scale activity and performance, relating electrophysiology, energy metabolism and cardiac mechanics. The fourth Goldberg Workshop continued the effort to elucidate the various parameters affecting cardiac performance, with emphasis on the ischemic heart. The fifth Workshop concentrated on the effect of the inhomogeneity of the cardiac muscle on its performance. The sixth Workshop highlighted new imaging techniques which allow insight into the local and global cardiac performance.

An Introductory Text To Bioengineering

Author : Shu Chien
Publisher : World Scientific Publishing Company
ISBN 13 : 9813101547
Total Pages : 563 pages
Book Rating : 4.8/5 (131 download)

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Book Synopsis An Introductory Text To Bioengineering by : Shu Chien

Download or read book An Introductory Text To Bioengineering written by Shu Chien and published by World Scientific Publishing Company. This book was released on 2008-05-27 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: This bestselling textbook will introduce undergraduate bioengineering students to the fundamental concepts and techniques, with the basic theme of integrative bioengineering. It covers bioengineering of several body systems, organs, tissues, and cells, integrating physiology at these levels with engineering concepts and approaches; novel developments in tissue engineering, regenerative medicine, nanoscience and nanotechnology; state-of-the-art knowledge in systems biology and bioinformatics; and socio-economic aspects of bioengineering.One of the distinctive features of the book is that it is integrative in nature (integration of biology, medicine and engineering, across different levels of the biological hierarchy, and basic knowledge with applications). It is unique in that it covers fundamental aspects of bioengineering, cutting-edge frontiers, and practical applications, as well as perspectives of bioengineering development. Furthermore, it covers important socio-economical aspects of bioengineering such as ethics and entrepreneurism.

Electrocardiology '96: From The Cell To The Body Surface: Proceedings Of The Xxiii International Congress On Electroc

Author : J Liebman
Publisher : World Scientific
ISBN 13 : 9814546240
Total Pages : 710 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Electrocardiology '96: From The Cell To The Body Surface: Proceedings Of The Xxiii International Congress On Electroc by : J Liebman

Download or read book Electrocardiology '96: From The Cell To The Body Surface: Proceedings Of The Xxiii International Congress On Electroc written by J Liebman and published by World Scientific. This book was released on 1997-07-01 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: This conference had as its focus the phrase 'From the Cell to the Body Surface'. It comprised five minisymposia, which concentrated on some of the major issues of the day for basic scientists and clinicians. In addition to the invited papers, the proceedings contain volume presentations and posters selected from among abstracts sent in by some of the most important investigators in electrocardiology worldwide.

Glycoimmunology

Author : Azita Alavi
Publisher : Springer Science & Business Media
ISBN 13 : 1461518857
Total Pages : 291 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Glycoimmunology by : Azita Alavi

Download or read book Glycoimmunology written by Azita Alavi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Third Jenner International Glycoimmunology meeting held in Il Ciocco, Tuscany, Italy, October 11-14, 1994

Heart Failure in the Child and Young Adult

Author : Joseph Rossano
Publisher : Academic Press
ISBN 13 : 0128026138
Total Pages : 826 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Heart Failure in the Child and Young Adult by : Joseph Rossano

Download or read book Heart Failure in the Child and Young Adult written by Joseph Rossano and published by Academic Press. This book was released on 2017-12-05 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart Failure in the Child and Young Adult: From Bench to Bedside combines multiple etiologies for pediatric heart failure, including congenital heart disease, cardiomyopathies, infectious diseases and metabolic abnormalities. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure, then progresses through diagnosis, management, treatment and surgery, finally concluding with advanced special topics, including genetics, self-management and nanomedicine. - Provides coverage of the basic science of heart failure, its epidemiology and economic aspects, outpatient and inpatient management, and advanced therapies, including mechanical circulatory support and heart transplantation - Combines cutting-edge research with current guidelines from the field

Cardiac Repolarization

Author : Ihor Gussak
Publisher : Springer Science & Business Media
ISBN 13 : 1592593623
Total Pages : 549 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Cardiac Repolarization by : Ihor Gussak

Download or read book Cardiac Repolarization written by Ihor Gussak and published by Springer Science & Business Media. This book was released on 2003-03-13 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of all the latest developments in cardiac electrophysiology, focusing on both the clinical and experimental aspects of ventricular repolarization, including newly discovered clinical repolarization syndromes, electrocardiographic phenomena, and their correlation with the most recent advances in basic science. The authors illuminate the basic electrophysiologic, molecular, and pharmacologic mechanisms underlying ventricular repolarization, relate them to specific disease conditions, and examine the future of antiarrhythmic drug development based on both molecular and electrophysiological properties. They also fully review the clinical presentation and management of specific cardiac repolarization conditions.

New Non-opioid Analgesics: Understanding Molecular Mechanisms on the Basis of Patch-clamp and chemical Studies

Author : Boris V. Krylov
Publisher : Bentham Science Publishers
ISBN 13 : 1608059308
Total Pages : 211 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis New Non-opioid Analgesics: Understanding Molecular Mechanisms on the Basis of Patch-clamp and chemical Studies by : Boris V. Krylov

Download or read book New Non-opioid Analgesics: Understanding Molecular Mechanisms on the Basis of Patch-clamp and chemical Studies written by Boris V. Krylov and published by Bentham Science Publishers. This book was released on 2017-06-12 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: The monograph is a summary of methods used to study pain receptors and the results obtained in some experiments designed to study the effect of non-opioid analgesics. The molecular mechanisms of nociceptive information control in primary sensory nociceptive neurons are described based on investigations of the membrane signaling cascade (opioid-like receptor → Na+,K+-ATPase → NaV1.8 channel) observed by the authors. Based on this data, the authors conclude that the modulation of NaV1.8 channels responsible for the coding of noxious signals can be carried out due to two novel targeting mechanisms. The first of these is the activation of opioid-like receptors; the second is the activation of Na+/K+-ATPase as a signal transducer. The development of a novel class of analgesics that trigger these mechanisms should lead to a successful solution to the problem of chronic pain relief. Chapters of the monograph cover the general methods used in studying nociceptive pain (including the patch-clamp method), and the mechanism behind the binding of different ligands to these receptors such gamma-pyrones, gamma-pyridines and cardiotonic steroids. This monograph is a valuable reference for neuroscientists, pharmacologists and allied researchers studying pain receptors for the development of safe and effective analgesics.

CT of the Heart

Author : U. Joseph Schoepf
Publisher : Springer Science & Business Media
ISBN 13 : 1592598188
Total Pages : 391 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis CT of the Heart by : U. Joseph Schoepf

Download or read book CT of the Heart written by U. Joseph Schoepf and published by Springer Science & Business Media. This book was released on 2007-10-27 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading clinicians and researchers from around the world review the full scope of current developments, research, and scientific controversy regarding the principles and applications of cardiac CT. Richly illustrated with numerous black-and-white and color images, the book discusses the interpretation of CT images of the heart in a variety of clinical, physiological, and pathological applications. The authors emphasize current state-of-the-art uses of CT, but also examine developments at the horizon. They also review the technical basis of CT image acquisition, as well as tools for image visualization and analysis.

Cellular and Molecular Alterations in the Failing Human Heart

Author : Hansjörg Just
Publisher : Springer Science & Business Media
ISBN 13 : 3642724744
Total Pages : 345 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Cellular and Molecular Alterations in the Failing Human Heart by : Hansjörg Just

Download or read book Cellular and Molecular Alterations in the Failing Human Heart written by Hansjörg Just and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: The myocardium in heart failure: Cellular and subcellular alterations in the failing human myocardium. H. Just Medizinische Universitatsklinik Freiburg i. Br., Innere Medizin III - Kardiologie, FRG The syndrome of heart failure continues to be a major challenge to clinicians and scientists. Incidence and mortality of the disease are high, the patient is disabled, and is permanently threatened by the high morbidity and mortality. The clinician faces a syndrome of complex pathophysiology. Multiple causes or underlying disorders of the heart have to be differentiated from heart failure itself, which often results in exceedingly difficult diagnoses. Likewise, prognostication meets with difficulties due to problems in separating influences of the underlying disease and the heart failure syndrome itself. In chronic refractory failure annual mortality may exceed 50%. If aortic stenosis or ischemic cardiomyopathy with main stem lesions are present, this percentage may be even higher. The situation becomes particularly threatening to the patient when the reduction in cardiac performance goes along with complex ventricular arrhythmias. Therapy has remained difficult and of limited effectiveness. Major progress was achieved with the introduction of diuretic substances. Of similar importance was the introduction of va so dilating drugs into the treatment of heart failure. The principle of vasodilation has greatly improved our understanding of the disease, and has brought about a major improvement of symptoms, increase of exercise capacity, and reduc tion of mortality. This is especially true for the introduction of the angiotensin converting enzyme inhibitors.

Control of the Cardiovascular and Respiratory Systems in Health and Disease

Author : C. Tissa Kappagoda
Publisher : Springer Science & Business Media
ISBN 13 : 1461518954
Total Pages : 226 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Control of the Cardiovascular and Respiratory Systems in Health and Disease by : C. Tissa Kappagoda

Download or read book Control of the Cardiovascular and Respiratory Systems in Health and Disease written by C. Tissa Kappagoda and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: On April 8-9, 1994, a symposium entitled Control of the Cardiovascular and Respiratory Systems in Health and Disease was held at the University of California Davis Medical Center in Sacramento. The purpose of this symposium was to honor the careers of Professors Hazel M. and John C. G. Coleridge. Participants in this symposium came from throughout the world. Their attendance at the symposium was a symbol of great respect and affection for the honorees. The Professors Coleridge have made many important contribu tions to the scientific literature concerning neural control of the cardiovascular and respira tory systems. In addition, they have made remarkable contributions to the lives of other scientists working in this field of investigation. Some of us have known them as mentors, counselors, friends, and supervisors; others have known them as co-investigators. Most importantly, all of us have known them as friends. This book, which contains the proceedings of the symposium, is dedicated to Hazel and John Coleridge. C. T. Kappagoda M. P. Kaufman v ACKNOWLEDGMENTS We wish to acknowledge the financial support of the following agencies for making this symposium a reality: • Astra Merck Group (Tarek Ackad, M. D. , Ph. D. ) • Boehringer Ingelheim Pharmaceuticals, Inc. (Ms. Kathryn B. Lucas and Mr. Allan Holloway) • Bristol-Myers Squibb (David L. Cram, Jr. , Pharm. D. ) • Marion/Merrrell Dow, Inc. (Mr. Brian Scheffield) • Merck and Company (Mr. Johnathan Sakakibara) • Pfizer Laboratories (Mr.

Microdomains in the Cardiovascular System

Author : Viacheslav Nikolaev
Publisher : Springer
ISBN 13 : 3319545795
Total Pages : 383 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Microdomains in the Cardiovascular System by : Viacheslav Nikolaev

Download or read book Microdomains in the Cardiovascular System written by Viacheslav Nikolaev and published by Springer. This book was released on 2017-09-19 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book comprehensively presents new findings in cardiovascular research related to signaling microdomains in health and disease. Important second messengers such as cAMP, cGMP, calcium and their role in microdomain signaling are discussed. The book offers and explains methodical approaches and technical ways how to successfully analyze microdomain signaling, also in the context of disease. It further provides scientific perspectives and strategies that are based on the concept of signaling within microdomains and that can revolutionize pharmacology and eventually lead to the effective treatment of cardiovascular diseases in future.This book is written for scientists in cardiovascular research, pharmacology, molecular and cellular biology as well as medical doctors in cardiology, angiology and nephrology.

Journal of Molecular and Cellular Cardiology

Author :
Publisher :
ISBN 13 :
Total Pages : 710 pages
Book Rating : 4.:/5 (36 download)

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Book Synopsis Journal of Molecular and Cellular Cardiology by :

Download or read book Journal of Molecular and Cellular Cardiology written by and published by . This book was released on 1987 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Subtilisin Enzymes

Author : Richard Bott
Publisher : Springer Science & Business Media
ISBN 13 : 1461303192
Total Pages : 287 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Subtilisin Enzymes by : Richard Bott

Download or read book Subtilisin Enzymes written by Richard Bott and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Subtilisin is the most extensively studied model system for protein engineering. The primary motivating factor for the interest in subtilisin is the commercial utility of this class of proteases. The subtilisin symposium was the first international meeting to bring together a large number of groups that have focused on the subtilisins and the subtilases-the protein superfamily of subtilisin-like enzymes. The results presented at the symposium are in this way a unique compendium of a broad spectrum of work largely focused on harnessing the potential of site-directed mutagenesis to understand and deliberately alter the function of these enzymes toward a desired end. This sort of protein engineering has been extremely successful in subtilisin, with many such "engineered" enzymes now widely used in commer cial enterprises. In this regard the experience derived from subtilisin does represent practical protein engineering. It is becoming clear that subtilisin represents a larger class of enzymes, the subtilases, that include many of the human pro hormone-converting enzymes. As international collabo rative efforts to sequence entire genomes continue, we can reasonably expect that additional members of the subtilase class will be encountered. Whenever interest in a member of this class of enzyme arises, the work on subtilisin will serve as a guide to the analysis for what in bacillus, fungi, and industry is an everyday workhorse enzyme.

Oxygen Transport to Tissue XXI

Author : Andras Eke
Publisher : Springer Science & Business Media
ISBN 13 : 1461547172
Total Pages : 775 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Oxygen Transport to Tissue XXI by : Andras Eke

Download or read book Oxygen Transport to Tissue XXI written by Andras Eke and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Society on Oxygen Transport to Tissue (lSOTT) held its 26th annual meeting from August 23-26, 1998, and met for the second time in Budapest. As captured in the design of the ISOTT'98 logo, the venue of the conference was the Budapest Hilton in the heart of the historic Castle District in Buda, across from Hungary's coronation church-the Matthias Church-and the fairy-tale-like Fisherman's Bastion; a special place with a historical touch situated atop the Castle Hill, from where participants enjoyed the spectacular panoramic views of Budapest exquisitely laid out on both sides of the Danube. In preparation for ISOTT'98, major emphasis was given to the application of informatics in collecting, presenting, and disseminating scientific and other information associated with the meeting. Electronic submission of the abstracts made it possible to publish the illustrated Abstracts on the ISOTT'98 Web Site well before the meeting. Following the meeting, an ISOTT'98 CD was published as a digital, searchable record of ISOTT'98. The scientific program was designed with the active participation of prospective attendees, in that priority and momentum was given to the topics selected by those visiting the Web Site. Poster and oral presentations were considered as equivalently effective formats, reflected by the fact that posters were on display throughout the meeting.

Immunobiology of Proteins and Peptides VIII

Author : M. Zouhair Atassi
Publisher : Springer Science & Business Media
ISBN 13 : 1461518911
Total Pages : 281 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Immunobiology of Proteins and Peptides VIII by : M. Zouhair Atassi

Download or read book Immunobiology of Proteins and Peptides VIII written by M. Zouhair Atassi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes the proceedings of the Eighth International Symposium on the Immunobiology of Proteins and Peptides which was held on November 16-20 in Rio Rico, Arizona. The articles represent papers by invited speakers as well as papers selected by the Scientific Council, from among those submitted by the participants, on the basis of quality and timeliness. This symposium series was established in 1976 for the purpose of bringing together, once every two or three years, active investigators in the forefront of contemporary immunology, to present their findings, discuss their significance in the light of current concepts and identify important new directions of investigation. The founding of the symposium was stimulated by the achievement of major breakthroughs in the understanding of the immune recognition of proteins and peptides. We believed that these breakthroughs would lead to the creation of a new generation of peptide reagents, which could have enormous potential in biological, therapeutic, and basic applications. This anticipated explosion has since occurred and many applications ofthese peptides are now being realized. The eighth symposium focused on the manipulation or modulation of the immune response. This volume broadly covers the areas of adjuvants, cytokines, vaccines, and the use of intravenous immunoglobulins for disease management. There is a clear need to identify methods for improving vaccine efficacy and guiding the host to respond with a particular type of immune response.

Complexity in Biological Information Processing

Author : Gregory R. Bock
Publisher : John Wiley & Sons
ISBN 13 : 9780471498322
Total Pages : 266 pages
Book Rating : 4.4/5 (983 download)

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Book Synopsis Complexity in Biological Information Processing by : Gregory R. Bock

Download or read book Complexity in Biological Information Processing written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2001-08-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many human diseases arise from the malfunction of signalling components, in particular alterations of multiple components of an integrated signalling network. Experimental and computational tools to describe and quantify these changes are increasingly available, providing a wealth of data that can stimulate systematic analysis of the entire signalling network and enable prediction of disease states not easily recognizable from complex data sets. This groundbreaking book explores the structural and temporal complexity in biological signalling exemplified in neuronal, immunological, humoral and genetic signal transduction networks. With discussions between experimentalists and theoretically oriented scientists, this book takes an interdisciplinary approach that may help switch the analysis of biological signalling from descriptive to predictive science and capture the behaviour of entire systems. Explores the structural and temporal complexity in biological signalling. Represents an unusual collocation of three different areas: immunology, cell signalling and neural networks. Contains interdisciplinary discussions between experimentalists and theoretically oriented scientists, in particular those working on computer simulations.