Glycoimmunology

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Glycoimmunology 2

Author : John S. Axford
Publisher : Springer Science & Business Media
ISBN 13 : 1461553830
Total Pages : 267 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Glycoimmunology 2 by : John S. Axford

Download or read book Glycoimmunology 2 written by John S. Axford and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Jenner International Glycoimmunology Meetings have charted the rapid devel opment of glycobiology within the field of inflammation. In less than a decade, the science has grown from basically being involved in carbohydrate analysis to the understanding of how sugars are associated with inflammation and how they have potential as anti inflammatory therapeutics. The 4th Jenner International Glycoimmunology Meeting was re cently held in Loutraki, Greece, and set the scene for what promises to be an exciting future for the speciality. Discussion reflected the rapid advances glycobiology is making and ranged from the basic biochemistry of carbohydrate physiology to therapeutic trials utilizing synthetic sugars designed to block inflammatory responses. The meeting is summarized in considerable detail in this book which will provide the interested scientist and clinician with the essential up-to-date facts within the field of glyco immunology. Acknowledgments Many people have been involved in ensuring the success of the Jenner Glycoimmu nology Meetings but none more so than my secretary Susan Henderson who has borne the brunt of all four meetings and is currently preparing for the 5th.

Glycoimmunology

Author : Azita Alavi
Publisher : Springer Science & Business Media
ISBN 13 : 1461518857
Total Pages : 291 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Glycoimmunology by : Azita Alavi

Download or read book Glycoimmunology written by Azita Alavi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Third Jenner International Glycoimmunology meeting held in Il Ciocco, Tuscany, Italy, October 11-14, 1994

Glycoimmunology 2

Author : John S Axford
Publisher :
ISBN 13 : 9781461553847
Total Pages : 288 pages
Book Rating : 4.5/5 (538 download)

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Book Synopsis Glycoimmunology 2 by : John S Axford

Download or read book Glycoimmunology 2 written by John S Axford and published by . This book was released on 1998-01-31 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Essentials of Glycobiology

Author : Ajit Varki
Publisher : CSHL Press
ISBN 13 : 9780879696818
Total Pages : 694 pages
Book Rating : 4.6/5 (968 download)

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Book Synopsis Essentials of Glycobiology by : Ajit Varki

Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Glycobiology and Medicine

Author : John S. Axford
Publisher : Springer Science & Business Media
ISBN 13 : 038725515X
Total Pages : 153 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Glycobiology and Medicine by : John S. Axford

Download or read book Glycobiology and Medicine written by John S. Axford and published by Springer Science & Business Media. This book was released on 2006-01-27 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: The potential for glycobiology to improve the practice of medicine has been well recognised, which is why biannual meetings concerning the association have been taking place for the last 14 years. The science of glycobiology has matured rapidly, and with it the far reaching clinical implications are becoming understood. The next decade is going to see this final frontier of science conquered. The impact this understanding of glycobiology will have upon our practice of medicine is going to be exciting. The 7th Jenner Glycobiology and Medicine Symposium was designed to reflect these advances. All the major clinical areas were involved, with contributions from pivotal players in science and medicine.

Anticarbohydrate Antibodies

Author : Paul Kosma
Publisher : Springer Science & Business Media
ISBN 13 : 9783709108703
Total Pages : 438 pages
Book Rating : 4.1/5 (87 download)

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Book Synopsis Anticarbohydrate Antibodies by : Paul Kosma

Download or read book Anticarbohydrate Antibodies written by Paul Kosma and published by Springer Science & Business Media. This book was released on 2011-11-27 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many pathogens and aberrant malignant cells express unique carbohydrates on their surface representing attractive targets for vaccine design. Considerable progress has recently been made in the identification of novel carbohydrate based vaccines and a large number has reached clinical phase studies. The success of several licensed carbohydrate based vaccines against bacterial pathogens such as Haemophilus influenzae type b, Neisseria meningitidis or Streptococcus pneumoniae demonstrates their great potential. However, the study of anti-carbohydrate antibodies is technically challenging and partly because of low affinities and promiscuous specificity they have not been medically exploited to full potential. The study of antibody specificities and identification of protective carbohydrate epitopes lies at the heart of successful vaccine design. In addition to therapy, antibodies in general serve as diagnostic tools in medical and scientific laboratories. In this setting high affinity and exquisite specificity are important factors for their successful use. “Anticarbohydrate Antibodies – from molecular basis to clinical application” compiles current knowledge on the immunological recognition of carbohydrates by the adaptive immune system from a molecular perspective providing fundamental insight needed for advancing clinically relevant diagnostics and therapeutic applications. Based on significant progress in the fields of glycoimmunology and structural biology in recent years, the book comprehensively reviews the state-of-the-art in defining the key elements of carbohydrate recognition by antibodies, the molecular mimicry of carbohydrate epitopes as well as the molecular features leading to specific and relaxed binding modes. Backed-up by a combination of modern technologies to elucidate structural details of carbohydrate-antibody interactions, biomedically important carbohydrate antigens from viral, bacterial, parasite, insect and tumor cells have been analyzed in in-depth reviews written by well-known experts in the field. Fundamental knowledge of these molecular mechanisms eventually provides a rational basis to improve efficacy of carbohydrate-based vaccines and to further refine diagnostic tools in detection of pathogens and malignant cells.

Lectin in Host Defense Against Microbial Infections

Author : Shie-Liang Hsieh
Publisher : Springer Nature
ISBN 13 : 9811515808
Total Pages : 240 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Lectin in Host Defense Against Microbial Infections by : Shie-Liang Hsieh

Download or read book Lectin in Host Defense Against Microbial Infections written by Shie-Liang Hsieh and published by Springer Nature. This book was released on 2020-03-09 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systemically presents the latest research on lectins, covering all the major topics in the field, including the heterocomplex of lectins and Toll-like receptors, protective versus pathogenic functions in connection with microbial infections, and novel strategies for enhancing host immunity against infectious diseases caused by viruses, bacteria, and fungi. Lectins are a large group of glycan-binding proteins that recognize diverse glycan and non-glycan structures expressed on prokaryotic and eukaryotic cells, and are vital to cell-cell interactions, the attachment of microbes to host cells, and the recognition and activation of immune responses to exogenous and endogenous danger signals. The composition and structure of microbes are complex and include numerous ‘pathogen-associated molecular patterns’ or ‘damage-associated molecular patterns’. As such, microbes’ interactions with immune cells activate multiple innate immunity receptors and produce distinct inflammatory reactions, which can be protective to contain microbial invasion, or pathogenic to cause tissue damage and shock syndrome in the host. The book shares lessons learned from state-of-the art research in this field, highlights the latest discoveries, and provides insightful discussions on lectin-mediated inflammatory reactions, while also outlining future research directions.

Glycoscience: Biology and Medicine

Author : Naoyuk Taniguchi
Publisher : Springer
ISBN 13 : 9784431548409
Total Pages : 0 pages
Book Rating : 4.5/5 (484 download)

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Book Synopsis Glycoscience: Biology and Medicine by : Naoyuk Taniguchi

Download or read book Glycoscience: Biology and Medicine written by Naoyuk Taniguchi and published by Springer. This book was released on 2014-11-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the book is to provide a succinct overview of the current status of glycoscience from both basic biological and medical points of view and to propose future directions, in order to facilitate further integrations of glycoscience with other fields in biological and medical studies. Glycans (carbohydrate oligomers) are the so-called “building blocks” of carbohydrates, nucleic acids, proteins and lipids and play major roles in many biological phenomena as well as in various pathophysiological processes. However, this area of glycoscience has been neglected from the research community because glycan structures are very complex and functionally diverse and as compared to proteins and nucleic acids simple tools for the amplification, sequencing and auto-synthesis of glycans are not available. Many scientists in other fields of research have now realized that glycosylation, i.e. the addition of glycans to a protein backbone, is the most abundant post translational modification reactions and is an important field of research and sometimes they require a glycobiology and/or glycochemistry approach to be used. It is still difficult, however, for non-expert researchers to use these techniques. This book provides numerous but simple overviews of current topics and protocols for the experiments. The book is aimed at university students and above, including non-experts in the field of glycoscience.

Addressing Roles for Glycans in Immunology using Chemical Biology

Author : Matthew S. Macauley
Publisher : Frontiers Media SA
ISBN 13 : 2889638669
Total Pages : 175 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Addressing Roles for Glycans in Immunology using Chemical Biology by : Matthew S. Macauley

Download or read book Addressing Roles for Glycans in Immunology using Chemical Biology written by Matthew S. Macauley and published by Frontiers Media SA. This book was released on 2020-07-17 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protein Engineering Techniques

Author : Krishna Mohan Poluri
Publisher : Springer
ISBN 13 : 9811027323
Total Pages : 134 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Protein Engineering Techniques by : Krishna Mohan Poluri

Download or read book Protein Engineering Techniques written by Krishna Mohan Poluri and published by Springer. This book was released on 2016-11-12 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brief provides a broad overview of protein-engineering research, offering a glimpse of the most common experimental methods. It also presents various computational programs with applications that are widely used in directed evolution, computational and de novo protein design. Further, it sheds light on the advantages and pitfalls of existing methodologies and future perspectives of protein engineering techniques.

Cummings Otolaryngology E-Book

Author : Paul W. Flint
Publisher : Elsevier Health Sciences
ISBN 13 : 0323612172
Total Pages : 4393 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Cummings Otolaryngology E-Book by : Paul W. Flint

Download or read book Cummings Otolaryngology E-Book written by Paul W. Flint and published by Elsevier Health Sciences. This book was released on 2020-04-22 with total page 4393 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most comprehensive, multi-disciplinary text in the field, Cummings Otolaryngology: Head and Neck Surgery, 7th Edition, provides detailed, practical answers and easily accessible clinical content on the complex issues that arise for otolaryngologists at all levels, across all subspecialties. This award-winning text is a one-stop reference for all stages of your career—from residency and board certification through the challenges faced in daily clinical practice. Updated content, new otology editor Dr. Howard W. Francis, and new chapters and videos ensure that this 7th Edition remains the definitive reference in today’s otolaryngology. Brings you up to date with the latest minimally invasive procedures, recent changes in rhinology, and new techniques and technologies that are shaping patient outcomes. Contains 12 new chapters, including Chronic Rhinosinusitis, Facial Pain, Geriatric Otology, Middle Ear Endoscopic Surgery, Pediatric Speech Disorders, Pediatric Cochlear Implantation, Tongue-Ties and Lip Ties, Laryngotracheal Clefts, and more. Covers recent advances and new approaches such as the Draf III procedure for CRS affecting the frontal recess, endoscopic vidian and posterior nasal neurectomy for non-allergic rhinitis, and endoscopic approaches for sinonasal and orbital tumors, both extra- and intraconal. Provides access to 70 key indicator (Accreditation Council for Graduate Medical Education Key Indicator Procedures), and surgical videos – an increase of 43% over the previous edition. Offers outstanding visual support with 4,000 high-quality images and hundreds of quick-reference tables and boxes.

Carbohydrate-Based Vaccines and Immunotherapies

Author : Zhongwu Guo
Publisher : John Wiley & Sons
ISBN 13 : 0470473274
Total Pages : 436 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Carbohydrate-Based Vaccines and Immunotherapies by : Zhongwu Guo

Download or read book Carbohydrate-Based Vaccines and Immunotherapies written by Zhongwu Guo and published by John Wiley & Sons. This book was released on 2009-06-17 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fundamental science and the latest developments in carbohydrate-based vaccines The relatively new field of glycoimmunology has emerged from the marriage of glycobiology and immunology, in recognition of the important role carbohydrates play as antigenic determinants. Carbohydrate-Based Vaccines and Immunotherapies comprehensively reviews the state of this exciting field, offering a single source for both the fundamental science and the latest developments. With contributions by leading experts, this resource covers the design, synthesis, evaluation, and applications of various carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids. The text approaches vaccine design from a chemical and molecular focus, staying in line with current advances. Key topics covered by Carbohydrate-Based Vaccines and Immunotherapies include: Recent developments towards clinically useful vaccines against bacteria, viruses, parasites, and fungi Using adjuvants to improve immunogenicity and/or immunological properties of vaccines Choosing and designing proper adjuvants for specific targets Abnormal carbohydrates expressed by tumors Carbohydrate-based therapeutic cancer vaccines or cancer immunotherapy Clinical trials results for synthetic cancer vaccines Glycoengineering of cell surface carborhydrates and its anticancer applications Using cell surface carbohydrates for disease diagnosis A single, convenient source of state-of-the-art information from leading authorities in the field, Carbohydrate-Based Vaccines and Immunotherapies is an essential reference for organic chemists and biochemists, academic researchers, and other students and professionals involved in vaccine design.

Carbohydrate Recognition

Author : Binghe Wang
Publisher : John Wiley & Sons
ISBN 13 : 0470592079
Total Pages : 448 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Carbohydrate Recognition by : Binghe Wang

Download or read book Carbohydrate Recognition written by Binghe Wang and published by John Wiley & Sons. This book was released on 2011-09-06 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.

Glycosylation and Cancer

Author :
Publisher : Academic Press
ISBN 13 : 0128016140
Total Pages : 418 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Glycosylation and Cancer by :

Download or read book Glycosylation and Cancer written by and published by Academic Press. This book was released on 2015-02-26 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. Provides information on cancer research Outstanding and original reviews Suitable for researchers and students

Translational Glycobiology in Human Health and Disease

Author : Michelle Kilcoyne
Publisher : Academic Press
ISBN 13 : 0128220023
Total Pages : 464 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Translational Glycobiology in Human Health and Disease by : Michelle Kilcoyne

Download or read book Translational Glycobiology in Human Health and Disease written by Michelle Kilcoyne and published by Academic Press. This book was released on 2023-11-29 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Along with nucleic acids, proteins, and lipids, carbohydrates stand as one of four main components of cellular architecture. However, glycobiology (or carbohydrate bioscience) is little understood by non-experts, partly because carbohydrates are a complex, diverse class of molecules structurally and functionally. In recent years, advances in computational analytics (glycomics) have allowed us to better interpret and realize the importance of glycobiology in human health and disease, and glycans and their associated processes have been shown to play a significant role across a variety of disease types. As the biomedical sciences continue to adopt multi-omic and precision medicine approaches, a greater understanding of glycobiology is essential for maintaining healthy physiology and advancing disease treatment.Translational Glycobiology in Human Health and Disease offers a deep examination of glycobiology for experts and non-experts alike in areas ranging from the role of glycobiology in chronic and infectious diseases to advances in technologies for higher throughput analysis and diagnosis. While keeping human health in the forefront, this book integrates a thorough discussion of glycobiology fundamentals with its growing areas of application and societal impact. With emphasis throughout on the interdisciplinary nature of glycosciences, this book also features perspectives from the health, computational (glycoanalytics), materials, biopharmaceutical, and diagnostic sciences.Disease and speciality areas addressed include gycoimmunology, neuroglycobiology, commensal glycobiology, gut health, regenerative medicine and glycobiology, glycobiology and cancer, congenital disorders of glycosylation, infectious disease glycobiology, and parasite glycobiology. Computational approaches discussed, supporting the advance of new research, include advanced glycoanalytics, glycomics microarrays, glycoengineering, and glycol systems biology. Additionally, authors consider impact areas for society and public health, such as glycobiology and entrepreneurship, policy and regulatory requirements for glycosylation, future research, and translation to new diagnostics and drug discovery. Provides a deep, foundational overview of glycoscience and its translational potential, highlighting glycobiology’s growing role in human health and disease study Examines a broad range of relevant disease areas and applications of glycobiology in policy and public health Features chapter contributions from leading, international experts in the field, fully integrating perspectives from the health, computational, materials, biopharmaceutical, and diagnostic sciences

Glycobiology of Innate Immunology

Author : Cheorl-Ho Kim
Publisher : Springer Nature
ISBN 13 : 9811690812
Total Pages : 673 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Glycobiology of Innate Immunology by : Cheorl-Ho Kim

Download or read book Glycobiology of Innate Immunology written by Cheorl-Ho Kim and published by Springer Nature. This book was released on 2022-03-31 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest knowledge and the most recent research results on glycobiology of innate immunology. Innate immunity is the crucial part of the immunological defense system that exerts their distinct functions through binding to certain functional glycoproteins. They play a role in various human diseases and also function against microbial invaders and self-associated molecular patterns. Co-regulated expression of glycan-binding is associated with many biological components such as cellular oncotransformation, phenotype change, neuronal or embryonic development, regulation of cell division, cell–cell interaction, cell attachment, adhesion, and motility, and intracellular signaling via protein–carbohydrate or carbohydrate–carbohydrate interactions. This book opens by providing the key background on glycans in innate immunity and its mechanisms behind the Dendritic cell interactions during infection and inflammation are examined in depth, and the concluding chapter is devoted to signaling tumor immunotherapy. Up-to-date information is then presented on all aspects of glycan structure-recognizing signaling. The book should assist in the further development of new strategies against emerging infectious agents and intractable diseases.

Green Polymeric Nanocomposites

Author : Satya Eswari Jujjavarapu
Publisher : CRC Press
ISBN 13 : 1351045148
Total Pages : 341 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Green Polymeric Nanocomposites by : Satya Eswari Jujjavarapu

Download or read book Green Polymeric Nanocomposites written by Satya Eswari Jujjavarapu and published by CRC Press. This book was released on 2020-01-28 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering fundamentals through applications, this book discusses environmentally friendly polymer nanocomposites and alternatives to traditional nanocomposites through detailed reviews of a variety of materials procured from different resources, their synthesis, and applications using alternative green approaches. The text: Describes green polymeric nanocomposites that show greater properties in terms of degradability, biocompatibility, synthesis process, cost effectiveness, mechanical strength, high surface area, nontoxicity, and environmental friendliness Explains the basics of eco-friendly polymer nanocomposites from different natural resources and their chemistry Discusses practical applications that present future directions in the biomedical, pharmaceutical, and automotive industries This book is aimed at scientists, researchers, and academics working in nanotechnology, biomaterials, polymer science, and those studying products derived from eco-friendly nanomaterials.