Molecular Advancements in Tropical Diseases Drug Discovery

Download Molecular Advancements in Tropical Diseases Drug Discovery PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128213973
Total Pages : 156 pages
Book Rating : 4.1/5 (282 download)

DOWNLOAD NOW!


Book Synopsis Molecular Advancements in Tropical Diseases Drug Discovery by : Gauri Misra

Download or read book Molecular Advancements in Tropical Diseases Drug Discovery written by Gauri Misra and published by Academic Press. This book was released on 2020-05-12 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Advancements in Tropical Diseases Drug Discovery presents in-depth knowledge relating to the detection of infection, epidemiology, drugs against various tropical diseases, new target sites for drug discovery and multidrug resistance issues using bioinformatics tools and approaches. The book's chapters are written by experts in their respective fields so that each disease is covered in a rational manner and with a solid foundation on existing facts and prospective research ideas. - Updates knowledge about tropical diseases with recent advancements in the field - Presents an overview of new research covering detection, infection, epidemiology and risk factors of the most common tropical diseases using bioinformatics tools - Encompasses a detailed description of developments in drug discovery, new drugs and their molecular mechanisms of action

Neglected Tropical Diseases and Phytochemicals in Drug Discovery

Download Neglected Tropical Diseases and Phytochemicals in Drug Discovery PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119617154
Total Pages : 624 pages
Book Rating : 4.1/5 (196 download)

DOWNLOAD NOW!


Book Synopsis Neglected Tropical Diseases and Phytochemicals in Drug Discovery by : Muhammad Akram

Download or read book Neglected Tropical Diseases and Phytochemicals in Drug Discovery written by Muhammad Akram and published by John Wiley & Sons. This book was released on 2021-10-25 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEGLECTED TROPICAL DISEASES AND PHYTOCHEMICALS IN DRUG DISCOVERY Explore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections. This book provides readers with insightful perspectives from leading industry voices on fifty years of trends and progress in the search for new, safe, and affordable therapeutic drugs in the fight against neglected tropical diseases. It includes information beneficial to researchers in a variety of fields of biology, chemistry, medicine, and pharmaceuticals. The distinguished authors cover topics including the effects of phytochemicals on the causative agent of leprosy and the potential applicability of phytochemicals in the management of Dengue fever. Readers will also enjoy the inclusion of: Thorough introductions to neglected tropical diseases, phytochemicals, protein targets, and mechanisms in drug discovery, as well as the epidemiology of neglected tropical diseases An exploration of novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis, and schistosomiasis Discussions of protozoan infections, including herbal, nutritional, and traditional remedies for giardiasis and the anti-leishmanial potentials of phytochemicals Examinations of helminth infections, including the prospects of phytochemicals in the treatment of helminthiasis Perfect for medicinal chemists, drug developers, and research and development scientists, Neglected Tropical Diseases and Phytochemicals in Drug Discovery will also earn a place in the libraries of toxicologists and researchers in biology, chemistry, medicinal chemistry, ethnobotany, and bioinformatics seeking a one-stop resource for drug discovery for neglected tropical diseases.

Neglected Tropical Diseases

Download Neglected Tropical Diseases PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527808620
Total Pages : 392 pages
Book Rating : 4.5/5 (278 download)

DOWNLOAD NOW!


Book Synopsis Neglected Tropical Diseases by : David C. Swinney

Download or read book Neglected Tropical Diseases written by David C. Swinney and published by John Wiley & Sons. This book was released on 2019-07-13 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: A drug discovery reference to the crippling tropical diseases that affect more than 1 billion people. Neglected Tropical Diseases is the first book of its kind to offer a guide that follows the World Health Organization?s list of neglected tropical diseases. The authors?all are experts on the topic?address the development of effective treatments for 12 crippling infectious diseases that affect almost 20% of the world?s popluation. The book includes information on the common approaches and the most important factors that lead to the development of new drugs for treating tropical diseases. Individual chapters review 12 neglected tropical diseases that are grouped by infectious agent, from viruses to bacteria to eukaryotic parasites. For each of these diseases, the book explains the unmet medical need and explores the current and potential drug discovery strategies. The book also includes information on potential drug compounds derived from natural products. This important book: -Ties together information from different sources for developing novel treatsments forneglected tropical diseases -Is aligned with WHO?s initiative to eradicate tropical diseases -Outlines current and potential drugs for treating tropical diseases -Provides a standard reference for the entire field Written for medicinal chemists, pharmaceutical chemists, pharmaceutical industry, virologists, parasitologists, and specialists on tropics medicine, Neglected Tropical Diseases offers an essential guide and a systematic reference for the development of successful treatments for 12 crippling infectious diseases.

Medicinal Chemistry Approaches to Malaria and Other Tropical Diseases

Download Medicinal Chemistry Approaches to Malaria and Other Tropical Diseases PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128205512
Total Pages : 234 pages
Book Rating : 4.1/5 (282 download)

DOWNLOAD NOW!


Book Synopsis Medicinal Chemistry Approaches to Malaria and Other Tropical Diseases by :

Download or read book Medicinal Chemistry Approaches to Malaria and Other Tropical Diseases written by and published by Academic Press. This book was released on 2019-10-25 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry Approaches to Malaria and Other Tropical Disease, Volume 53 in the Annual Reports in Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Annual Reports in Medicinal Chemistry series - Includes the latest information on Medicinal Approaches to Malaria and Other Tropical Diseases

Recent Advances in the Synthesis of Organic Compounds to Combat Neglected Tropical Diseases

Download Recent Advances in the Synthesis of Organic Compounds to Combat Neglected Tropical Diseases PDF Online Free

Author :
Publisher : Bentham Science Publishers
ISBN 13 : 1608059022
Total Pages : 285 pages
Book Rating : 4.6/5 (8 download)

DOWNLOAD NOW!


Book Synopsis Recent Advances in the Synthesis of Organic Compounds to Combat Neglected Tropical Diseases by : Adilson Beatriz

Download or read book Recent Advances in the Synthesis of Organic Compounds to Combat Neglected Tropical Diseases written by Adilson Beatriz and published by Bentham Science Publishers. This book was released on 2014-08-04 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: The World Health Organization (WHO) has reported 14 diseases that are occurring exclusively in tropical areas. Most of these diseases are infectious and mainly affect poor populations. Some of these diseases include malaria, dengue fever, leishmaniasis and Chagas disease. Therefore, an acute need for increasing the arsenal of drugs is required to fight against these neglected diseases for the guaranteed recovery and relief of many patients. This E-book gathers important scientific research performed by scientists worldwide showing the state of the art of Medicinal Chemistry dedicated to the synthesis of compounds that are potentially bioactive against the causative agents of neglected diseases. The contents of this book include chapters on recent advances in synthetic organic compounds for the prevention of Chagas disease, recent advances in the discovery of small organic molecules for the prevention and treatment of dengue fever, leishmaniasis, leprosy, therapeutic arsenal and drug discovery for lymphatic filariasis, therapeutic agents for the treatment of malaria, schistosomiasis and synthetic organic compounds as potential antitubercular drugs. This book is intended for undergraduate and graduate students in institutes, colleges, universities and academies who want to specialize in the field of organic synthesis and medicinal chemistry.This book will also be a valuable resource of information for researchers in this field.

Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases

Download Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0128157240
Total Pages : 461 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!


Book Synopsis Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases by : Goutam Brahmachari

Download or read book Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases written by Goutam Brahmachari and published by Elsevier. This book was released on 2019-04-15 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more. In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases. - Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery - Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases - Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases

Malaria

Download Malaria PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 9780309045278
Total Pages : 312 pages
Book Rating : 4.0/5 (452 download)

DOWNLOAD NOW!


Book Synopsis Malaria by : Institute of Medicine

Download or read book Malaria written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.

Reactive Oxygen Species

Download Reactive Oxygen Species PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030685101
Total Pages : 425 pages
Book Rating : 4.0/5 (36 download)

DOWNLOAD NOW!


Book Synopsis Reactive Oxygen Species by : Harald H. H. W. Schmidt

Download or read book Reactive Oxygen Species written by Harald H. H. W. Schmidt and published by Springer Nature. This book was released on 2021-02-23 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Disease Control Priorities, Third Edition (Volume 6)

Download Disease Control Priorities, Third Edition (Volume 6) PDF Online Free

Author :
Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

DOWNLOAD NOW!


Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Design of Hybrid Molecules for Drug Development

Download Design of Hybrid Molecules for Drug Development PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0081011180
Total Pages : 354 pages
Book Rating : 4.0/5 (81 download)

DOWNLOAD NOW!


Book Synopsis Design of Hybrid Molecules for Drug Development by : Michael Decker

Download or read book Design of Hybrid Molecules for Drug Development written by Michael Decker and published by Elsevier. This book was released on 2017-04-05 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design of Hybrid Molecules for Drug Development reviews the principles, advantages, and limitations involved with designing these groundbreaking compounds. Beginning with an introduction to hybrid molecule design and background as to their need, the book goes on to explore a range of important hybrids, with hybrids containing natural products, molecules containing NO- and H2S-donors, dual-acting compounds acting as receptor ligands and enzyme inhibitors, and the design of photoresponsive drugs all discussed. Drawing on practical case studies, the hybridization of molecules for development as treatments for a number of key diseases is then outlined, including the design of hybrids for Alzheimer's, cancer, and malaria. With its cutting-edge reviews of breaking developments in this exciting field, the book offers a novel approach for all those working in the design, development, and administration of drugs for a range of debilitating disorders. - Highlights an approach unimpaired by the limitations of the classical search for lead structures - one of the core problems in modern drug development processes, making the content of high relevance for both academic and non-academic drug development processes - Pulls together research and design techniques in a novel way to give researchers the best possible platform from which to review the approaches and techniques applied - Compares the advantages and disadvantages of these compounds - Includes the very latest developments, such as photoactivatable and photo-responsive drugs

Travelers' Malaria

Download Travelers' Malaria PDF Online Free

Author :
Publisher : PMPH-USA
ISBN 13 : 9781550093360
Total Pages : 428 pages
Book Rating : 4.0/5 (933 download)

DOWNLOAD NOW!


Book Synopsis Travelers' Malaria by : Patricia Schlagenhauf-Lawlor

Download or read book Travelers' Malaria written by Patricia Schlagenhauf-Lawlor and published by PMPH-USA. This book was released on 2008 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Travelers' Malaria is considered an essential resource for practitioners of travel medicine. This updated book focuses on the epidemiology, prevention and treatment of malaria in non-immune travelers and immigrants. Each chapter is an up-to-date monograph (with an abstract) and contains detailed references to published literature as well as to appropriate web sites. The purpose of the book is to serve as a reference for specialists in the field and for any practitioner who may confront the complexities of caring for malaria-exposed travelers in both pre- and post-travel settings.Travelers' Malaria contains 26 chapters.

Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design

Download Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 9811589364
Total Pages : 334 pages
Book Rating : 4.8/5 (115 download)

DOWNLOAD NOW!


Book Synopsis Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design by : Sanjeev Kumar Singh

Download or read book Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design written by Sanjeev Kumar Singh and published by Springer Nature. This book was released on 2021-02-02 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents various computer-aided drug discovery methods for the design and development of ligand and structure-based drug molecules. A wide variety of computational approaches are now being used in various stages of drug discovery and development, as well as in clinical studies. Yet, despite the rapid advances in computer software and hardware, combined with the exponential growth in the available biological information, there are many challenges that still need to be addressed, as this book shows. In turn, it shares valuable insights into receptor-ligand interactions in connection with various biological functions and human diseases. The book discusses a wide range of phylogenetic methods and highlights the applications of Molecular Dynamics Simulation in the drug discovery process. It also explores the application of quantum mechanics in order to provide better accuracy when calculating protein-ligand binding interactions and predicting binding affinities. In closing, the book provides illustrative descriptions of major challenges associated with computer-aided drug discovery for the development of therapeutic drugs. Given its scope, it offers a valuable asset for life sciences researchers, medicinal chemists and bioinformaticians looking for the latest information on computer-aided methodologies for drug development, together with their applications in drug discovery.

Advances in Malaria Research

Download Advances in Malaria Research PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118493796
Total Pages : 611 pages
Book Rating : 4.1/5 (184 download)

DOWNLOAD NOW!


Book Synopsis Advances in Malaria Research by : Deepak Gaur

Download or read book Advances in Malaria Research written by Deepak Gaur and published by John Wiley & Sons. This book was released on 2016-12-27 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly reviews our current understanding of malarial biology Explores the subject with insights from post-genomic technologies Looks broadly at the disease, vectors of infection, and treatment and prevention strategies A timely publication with chapters written by global researchers leaders

Proceedings of 9th International Conference and Exhibition on Chinese Medicine, Ayurveda & Acupuncture 2018

Download Proceedings of 9th International Conference and Exhibition on Chinese Medicine, Ayurveda & Acupuncture 2018 PDF Online Free

Author :
Publisher : ConferenceSeries
ISBN 13 :
Total Pages : 78 pages
Book Rating : 4./5 ( download)

DOWNLOAD NOW!


Book Synopsis Proceedings of 9th International Conference and Exhibition on Chinese Medicine, Ayurveda & Acupuncture 2018 by : ConferenceSeries

Download or read book Proceedings of 9th International Conference and Exhibition on Chinese Medicine, Ayurveda & Acupuncture 2018 written by ConferenceSeries and published by ConferenceSeries. This book was released on with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: March 12-13, 2018 Barcelona, Spain Key Topics : Traditional Chinese Medicine, Acupuncture, The Ayurveda : Eight Components, Branches of Alternative Medicines, Chinese Herbology, Folk Medicine, Homeopathy, Unani Medicology, Tibetan Medication, Mongolian Medicine, Chinese Nutrition, Acupuncture and Naturotherapy, Oriental Medicine, Traditional Physical Therapy, Holistic Therapy: Body, Mind, Spirit & Soul., Korean Medicine, Traditional African Medicine,

RethinkHIV

Download RethinkHIV PDF Online Free

Author :
Publisher : Cambridge University Press
ISBN 13 : 1107028698
Total Pages : 387 pages
Book Rating : 4.1/5 (7 download)

DOWNLOAD NOW!


Book Synopsis RethinkHIV by : Bjørn Lomborg

Download or read book RethinkHIV written by Bjørn Lomborg and published by Cambridge University Press. This book was released on 2012-10-18 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely thought-provoking book, which examines the first-ever comparative cost-benefit analysis of responses to HIV/AIDS in Africa.

Computational Pharmaceutics

Download Computational Pharmaceutics PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118573994
Total Pages : 350 pages
Book Rating : 4.1/5 (185 download)

DOWNLOAD NOW!


Book Synopsis Computational Pharmaceutics by : Defang Ouyang

Download or read book Computational Pharmaceutics written by Defang Ouyang and published by John Wiley & Sons. This book was released on 2015-07-20 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular modeling techniques have been widely used in drug discovery fields for rational drug design and compound screening. Now these techniques are used to model or mimic the behavior of molecules, and help us study formulation at the molecular level. Computational pharmaceutics enables us to understand the mechanism of drug delivery, and to develop new drug delivery systems. The book discusses the modeling of different drug delivery systems, including cyclodextrins, solid dispersions, polymorphism prediction, dendrimer-based delivery systems, surfactant-based micelle, polymeric drug delivery systems, liposome, protein/peptide formulations, non-viral gene delivery systems, drug-protein binding, silica nanoparticles, carbon nanotube-based drug delivery systems, diamond nanoparticles and layered double hydroxides (LDHs) drug delivery systems. Although there are a number of existing books about rational drug design with molecular modeling techniques, these techniques still look mysterious and daunting for pharmaceutical scientists. This book fills the gap between pharmaceutics and molecular modeling, and presents a systematic and overall introduction to computational pharmaceutics. It covers all introductory, advanced and specialist levels. It provides a totally different perspective to pharmaceutical scientists, and will greatly facilitate the development of pharmaceutics. It also helps computational chemists to look for the important questions in the drug delivery field. This book is included in the Advances in Pharmaceutical Technology book series.

An Overview of Tropical Diseases

Download An Overview of Tropical Diseases PDF Online Free

Author :
Publisher : BoD – Books on Demand
ISBN 13 : 953512224X
Total Pages : 214 pages
Book Rating : 4.5/5 (351 download)

DOWNLOAD NOW!


Book Synopsis An Overview of Tropical Diseases by : Amidou Samie

Download or read book An Overview of Tropical Diseases written by Amidou Samie and published by BoD – Books on Demand. This book was released on 2015-12-02 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tropical diseases affect millions of people throughout the world and particularly in the developing countries. The millennium development goals had specifically targeted HIV/AIDS and Malaria for substantial reduction as well as Tuberculosis while many other tropical diseases have been neglected. The new sustainable development goals have not made such distinction and have targeted all diseases for elimination for the improvement of the quality of life of human beings on earth. The present book was developed to provide an update on issues relevant to the treatment of selected tropical diseases such as tuberculosis, malaria, leishmaniasis, schistosomiasis and ectoparasites such as chiggers which are widely distributed throughout the world. The control of these infections has been hampered by the development of drug resistance and the lack of the development of new and more effective drugs. The understanding of the biochemical processes underlying drug activity is therefore essential for the potential elimination of these infections.