Modelling Survival Data in Medical Research

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Publisher : CRC Press
ISBN 13 : 1498731694
Total Pages : 548 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Modelling Survival Data in Medical Research by : David Collett

Download or read book Modelling Survival Data in Medical Research written by David Collett and published by CRC Press. This book was released on 2015-05-04 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modelling Survival Data in Medical Research describes the modelling approach to the analysis of survival data using a wide range of examples from biomedical research.Well known for its nontechnical style, this third edition contains new chapters on frailty models and their applications, competing risks, non-proportional hazards, and dependent censo

Modelling Survival Data in Medical Research, Second Edition

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Publisher : CRC Press
ISBN 13 : 1584883251
Total Pages : 413 pages
Book Rating : 4.5/5 (848 download)

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Book Synopsis Modelling Survival Data in Medical Research, Second Edition by : David Collett

Download or read book Modelling Survival Data in Medical Research, Second Edition written by David Collett and published by CRC Press. This book was released on 2003-03-28 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critically acclaimed and resoundingly popular in its first edition, Modelling Survival Data in Medical Research has been thoroughly revised and updated to reflect the many developments and advances--particularly in software--made in the field over the last 10 years. Now, more than ever, it provides an outstanding text for upper-level and graduate courses in survival analysis, biostatistics, and time-to-event analysis.The treatment begins with an introduction to survival analysis and a description of four studies that lead to survival data. Subsequent chapters then use those data sets and others to illustrate the various analytical techniques applicable to such data, including the Cox regression model, the Weibull proportional hazards model, and others. This edition features a more detailed treatment of topics such as parametric models, accelerated failure time models, and analysis of interval-censored data. The author also focuses the software section on the use of SAS, summarising the methods used by the software to generate its output and examining that output in detail. Profusely illustrated with examples and written in the author's trademark, easy-to-follow style, Modelling Survival Data in Medical Research, Second Edition is a thorough, practical guide to survival analysis that reflects current statistical practices.

Modelling Survival Data in Medical Research

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Author :
Publisher : Chapman and Hall/CRC
ISBN 13 :
Total Pages : 388 pages
Book Rating : 4.3/5 (97 download)

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Book Synopsis Modelling Survival Data in Medical Research by : D. Collett

Download or read book Modelling Survival Data in Medical Research written by D. Collett and published by Chapman and Hall/CRC. This book was released on 1994 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to modelling survival data in medical research. It demonstrates how widely available computer software can be used in survival analysis. It seeks to provide sufficient methodological development for the reader to understand assumptions upon which techniques are based, and to help the reader to adapt the methodology to deal with non-standard problems.

Modelling Survival Data in Medical Research

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Publisher :
ISBN 13 : 9780429258374
Total Pages : 368 pages
Book Rating : 4.2/5 (583 download)

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Book Synopsis Modelling Survival Data in Medical Research by : David Collett

Download or read book Modelling Survival Data in Medical Research written by David Collett and published by . This book was released on 1993 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data collected on the time to an event-such as the death of a patient in a medical study-is known as survival data. The methods for analyzing survival data can also be used to analyze data on the time to events such as the recurrence of a disease or relief from symptoms. Modelling Survival Data in Medical Research begins with an introduction to survival analysis and a description of four studies in which survival data was obtained. These and other data sets are then used to illustrate the techniques presented in the following chapters, including the Cox and Weibull proportional hazards models; accelerated failure time models; models with time-dependent variables; interval-censored survival data; model checking; and use of statistical packages. Designed for statisticians in the pharmaceutical industry and medical research institutes, and for numerate scientists and clinicians analyzing their own data sets, this book also meets the need for an intermediate text which emphasizes the application of the methodology to survival data arising from medical studies.

Modelling Survival Data in Medical Research, Third Edition

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Publisher : Chapman and Hall/CRC
ISBN 13 : 9781439856789
Total Pages : 548 pages
Book Rating : 4.8/5 (567 download)

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Book Synopsis Modelling Survival Data in Medical Research, Third Edition by : David Collett

Download or read book Modelling Survival Data in Medical Research, Third Edition written by David Collett and published by Chapman and Hall/CRC. This book was released on 2014-12-11 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modelling Survival Data in Medical Research describes the modelling approach to the analysis of survival data using a wide range of examples from biomedical research. Well known for its nontechnical style, this third edition contains new chapters on frailty models and their applications, competing risks, non-proportional hazards, and dependent censoring. It also describes techniques for modelling the occurrence of multiple events and event history analysis. Earlier chapters are now expanded to include new material on a number of topics, including measures of predictive ability and flexible parametric models. Many new data sets and examples are included to illustrate how these techniques are used in modelling survival data. Bibliographic notes and suggestions for further reading are provided at the end of each chapter. Additional data sets to obtain a fuller appreciation of the methodology, or to be used as student exercises, are provided in the appendix. All data sets used in this book are also available in electronic format online. This book is an invaluable resource for statisticians in the pharmaceutical industry, professionals in medical research institutes, scientists and clinicians who are analyzing their own data, and students taking undergraduate or postgraduate courses in survival analysis.

Modeling Survival Data: Extending the Cox Model

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Publisher : Springer Science & Business Media
ISBN 13 : 1475732945
Total Pages : 356 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Modeling Survival Data: Extending the Cox Model by : Terry M. Therneau

Download or read book Modeling Survival Data: Extending the Cox Model written by Terry M. Therneau and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is for statistical practitioners, particularly those who design and analyze studies for survival and event history data. Building on recent developments motivated by counting process and martingale theory, it shows the reader how to extend the Cox model to analyze multiple/correlated event data using marginal and random effects. The focus is on actual data examples, the analysis and interpretation of results, and computation. The book shows how these new methods can be implemented in SAS and S-Plus, including computer code, worked examples, and data sets.

Modelling Survival Data in Medical Research, Second Edition

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (14 download)

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Book Synopsis Modelling Survival Data in Medical Research, Second Edition by : David Collett

Download or read book Modelling Survival Data in Medical Research, Second Edition written by David Collett and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Applied Survival Analysis

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Publisher : John Wiley & Sons
ISBN 13 : 1118211588
Total Pages : 285 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Applied Survival Analysis by : David W. Hosmer, Jr.

Download or read book Applied Survival Analysis written by David W. Hosmer, Jr. and published by John Wiley & Sons. This book was released on 2011-09-23 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE MOST PRACTICAL, UP-TO-DATE GUIDE TO MODELLING AND ANALYZING TIME-TO-EVENT DATA—NOW IN A VALUABLE NEW EDITION Since publication of the first edition nearly a decade ago, analyses using time-to-event methods have increase considerably in all areas of scientific inquiry mainly as a result of model-building methods available in modern statistical software packages. However, there has been minimal coverage in the available literature to9 guide researchers, practitioners, and students who wish to apply these methods to health-related areas of study. Applied Survival Analysis, Second Edition provides a comprehensive and up-to-date introduction to regression modeling for time-to-event data in medical, epidemiological, biostatistical, and other health-related research. This book places a unique emphasis on the practical and contemporary applications of regression modeling rather than the mathematical theory. It offers a clear and accessible presentation of modern modeling techniques supplemented with real-world examples and case studies. Key topics covered include: variable selection, identification of the scale of continuous covariates, the role of interactions in the model, assessment of fit and model assumptions, regression diagnostics, recurrent event models, frailty models, additive models, competing risk models, and missing data. Features of the Second Edition include: Expanded coverage of interactions and the covariate-adjusted survival functions The use of the Worchester Heart Attack Study as the main modeling data set for illustrating discussed concepts and techniques New discussion of variable selection with multivariable fractional polynomials Further exploration of time-varying covariates, complex with examples Additional treatment of the exponential, Weibull, and log-logistic parametric regression models Increased emphasis on interpreting and using results as well as utilizing multiple imputation methods to analyze data with missing values New examples and exercises at the end of each chapter Analyses throughout the text are performed using Stata® Version 9, and an accompanying FTP site contains the data sets used in the book. Applied Survival Analysis, Second Edition is an ideal book for graduate-level courses in biostatistics, statistics, and epidemiologic methods. It also serves as a valuable reference for practitioners and researchers in any health-related field or for professionals in insurance and government.

Survival Analysis for Epidemiologic and Medical Research

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Publisher : Cambridge University Press
ISBN 13 : 1139471244
Total Pages : 219 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Survival Analysis for Epidemiologic and Medical Research by : Steve Selvin

Download or read book Survival Analysis for Epidemiologic and Medical Research written by Steve Selvin and published by Cambridge University Press. This book was released on 2008-03-03 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical guide to survival data and its analysis for readers with a minimal background in statistics shows why the analytic methods work and how to effectively analyze and interpret epidemiologic and medical survival data with the help of modern computer systems. The introduction presents a review of a variety of statistical methods that are not only key elements of survival analysis but are also central to statistical analysis in general. Techniques such as statistical tests, transformations, confidence intervals, and analytic modeling are presented in the context of survival data but are, in fact, statistical tools that apply to understanding the analysis of many kinds of data. Similarly, discussions of such statistical concepts as bias, confounding, independence, and interaction are presented in the context of survival analysis and also are basic components of a broad range of applications. These topics make up essentially a 'second-year', one-semester biostatistics course in survival analysis concepts and techniques for non-statisticians.

Analysing Survival Data from Clinical Trials and Observational Studies

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Publisher : John Wiley & Sons
ISBN 13 : 9780470093412
Total Pages : 436 pages
Book Rating : 4.0/5 (934 download)

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Book Synopsis Analysing Survival Data from Clinical Trials and Observational Studies by : Ettore Marubini

Download or read book Analysing Survival Data from Clinical Trials and Observational Studies written by Ettore Marubini and published by John Wiley & Sons. This book was released on 2004-07-02 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide to methods of survival analysis for medical researchers with limited statistical experience. Methods and techniques described range from descriptive and exploratory analysis to multivariate regression methods. Uses illustrative data from actual clinical trials and observational studies to describe methods of analysing and reporting results. Also reviews the features and performance of statistical software available for applying the methods of analysis discussed.

Survival Analysis in Medicine and Genetics

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Publisher : CRC Press
ISBN 13 : 1439893144
Total Pages : 381 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Survival Analysis in Medicine and Genetics by : Jialiang Li

Download or read book Survival Analysis in Medicine and Genetics written by Jialiang Li and published by CRC Press. This book was released on 2013-06-04 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using real data sets throughout, Survival Analysis in Medicine and Genetics introduces the latest methods for analyzing high-dimensional survival data. It provides thorough coverage of recent statistical developments in the medical and genetics fields. The text mainly addresses special concerns of the survival model. After covering the fundamentals

Regression Models as a Tool in Medical Research

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Publisher : CRC Press
ISBN 13 : 1466517484
Total Pages : 497 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Regression Models as a Tool in Medical Research by : Werner Vach

Download or read book Regression Models as a Tool in Medical Research written by Werner Vach and published by CRC Press. This book was released on 2012-11-27 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: While regression models have become standard tools in medical research, understanding how to properly apply the models and interpret the results is often challenging for beginners. Regression Models as a Tool in Medical Research presents the fundamental concepts and important aspects of regression models most commonly used in medical research, including the classical regression model for continuous outcomes, the logistic regression model for binary outcomes, and the Cox proportional hazards model for survival data. The text emphasizes adequate use, correct interpretation of results, appropriate presentation of results, and avoidance of potential pitfalls. After reviewing popular models and basic methods, the book focuses on advanced topics and techniques. It considers the comparison of regression coefficients, the selection of covariates, the modeling of nonlinear and nonadditive effects, and the analysis of clustered and longitudinal data, highlighting the impact of selection mechanisms, measurement error, and incomplete covariate data. The text then covers the use of regression models to construct risk scores and predictors. It also gives an overview of more specific regression models and their applications as well as alternatives to regression modeling. The mathematical details underlying the estimation and inference techniques are provided in the appendices.

Statistical Modelling of Survival Data with Random Effects

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Publisher : Springer
ISBN 13 : 9811065578
Total Pages : 283 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Statistical Modelling of Survival Data with Random Effects by : Il Do Ha

Download or read book Statistical Modelling of Survival Data with Random Effects written by Il Do Ha and published by Springer. This book was released on 2018-01-02 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a groundbreaking introduction to the likelihood inference for correlated survival data via the hierarchical (or h-) likelihood in order to obtain the (marginal) likelihood and to address the computational difficulties in inferences and extensions. The approach presented in the book overcomes shortcomings in the traditional likelihood-based methods for clustered survival data such as intractable integration. The text includes technical materials such as derivations and proofs in each chapter, as well as recently developed software programs in R (“frailtyHL”), while the real-world data examples together with an R package, “frailtyHL” in CRAN, provide readers with useful hands-on tools. Reviewing new developments since the introduction of the h-likelihood to survival analysis (methods for interval estimation of the individual frailty and for variable selection of the fixed effects in the general class of frailty models) and guiding future directions, the book is of interest to researchers in medical and genetics fields, graduate students, and PhD (bio) statisticians.

Extending SAS Survival Analysis Techniques for Medical Research

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Publisher :
ISBN 13 :
Total Pages : 212 pages
Book Rating : 4.3/5 (97 download)

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Book Synopsis Extending SAS Survival Analysis Techniques for Medical Research by : Alan B. Cantor

Download or read book Extending SAS Survival Analysis Techniques for Medical Research written by Alan B. Cantor and published by . This book was released on 1997 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Survival Analysis Using S

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Publisher : CRC Press
ISBN 13 : 0203501411
Total Pages : 277 pages
Book Rating : 4.2/5 (35 download)

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Book Synopsis Survival Analysis Using S by : Mara Tableman

Download or read book Survival Analysis Using S written by Mara Tableman and published by CRC Press. This book was released on 2003-07-28 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survival Analysis Using S: Analysis of Time-to-Event Data is designed as a text for a one-semester or one-quarter course in survival analysis for upper-level or graduate students in statistics, biostatistics, and epidemiology. Prerequisites are a standard pre-calculus first course in probability and statistics, and a course in applied linear regression models. No prior knowledge of S or R is assumed. A wide choice of exercises is included, some intended for more advanced students with a first course in mathematical statistics. The authors emphasize parametric log-linear models, while also detailing nonparametric procedures along with model building and data diagnostics. Medical and public health researchers will find the discussion of cut point analysis with bootstrap validation, competing risks and the cumulative incidence estimator, and the analysis of left-truncated and right-censored data invaluable. The bootstrap procedure checks robustness of cut point analysis and determines cut point(s). In a chapter written by Stephen Portnoy, censored regression quantiles - a new nonparametric regression methodology (2003) - is developed to identify important forms of population heterogeneity and to detect departures from traditional Cox models. By generalizing the Kaplan-Meier estimator to regression models for conditional quantiles, this methods provides a valuable complement to traditional Cox proportional hazards approaches.

Dynamic Prediction in Clinical Survival Analysis

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Publisher : CRC Press
ISBN 13 : 1439835438
Total Pages : 250 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Dynamic Prediction in Clinical Survival Analysis by : Hans van Houwelingen

Download or read book Dynamic Prediction in Clinical Survival Analysis written by Hans van Houwelingen and published by CRC Press. This book was released on 2011-11-09 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a huge amount of literature on statistical models for the prediction of survival after diagnosis of a wide range of diseases like cancer, cardiovascular disease, and chronic kidney disease. Current practice is to use prediction models based on the Cox proportional hazards model and to present those as static models for remaining lifetime a

Analysis of Failure and Survival Data

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Publisher : CRC Press
ISBN 13 : 9781584880752
Total Pages : 268 pages
Book Rating : 4.8/5 (87 download)

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Book Synopsis Analysis of Failure and Survival Data by : Peter J. Smith

Download or read book Analysis of Failure and Survival Data written by Peter J. Smith and published by CRC Press. This book was released on 2002-02-26 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analysis of Failure and Survival Data is an essential textbook for graduate-level students of survival analysis and reliability and a valuable reference for practitioners. It focuses on the many techniques that appear in popular software packages, including plotting product-limit survival curves, hazard plots, and probability plots in the context of censored data. The author integrates S-Plus and Minitab output throughout the text, along with a variety of real data sets so readers can see how the theory and methods are applied. He also incorporates exercises in each chapter that provide valuable problem-solving experience. In addition to all of this, the book also brings to light the most recent linear regression techniques. Most importantly, it includes a definitive account of the Buckley-James method for censored linear regression, found to be the best performing method when a Cox proportional hazards method is not appropriate. Applying the theories of survival analysis and reliability requires more background and experience than students typically receive at the undergraduate level. Mastering the contents of this book will help prepare students to begin performing research in survival analysis and reliability and provide seasoned practitioners with a deeper understanding of the field.