Modeling Multistate Models With Back Transitions Statistical Challenges And Applications

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Multi-State Survival Models for Interval-Censored Data

Author : Ardo van den Hout
Publisher : CRC Press
ISBN 13 : 1315356732
Total Pages : 323 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Multi-State Survival Models for Interval-Censored Data by : Ardo van den Hout

Download or read book Multi-State Survival Models for Interval-Censored Data written by Ardo van den Hout and published by CRC Press. This book was released on 2016-11-25 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multi-State Survival Models for Interval-Censored Data introduces methods to describe stochastic processes that consist of transitions between states over time. It is targeted at researchers in medical statistics, epidemiology, demography, and social statistics. One of the applications in the book is a three-state process for dementia and survival in the older population. This process is described by an illness-death model with a dementia-free state, a dementia state, and a dead state. Statistical modelling of a multi-state process can investigate potential associations between the risk of moving to the next state and variables such as age, gender, or education. A model can also be used to predict the multi-state process. The methods are for longitudinal data subject to interval censoring. Depending on the definition of a state, it is possible that the time of the transition into a state is not observed exactly. However, when longitudinal data are available the transition time may be known to lie in the time interval defined by two successive observations. Such an interval-censored observation scheme can be taken into account in the statistical inference. Multi-state modelling is an elegant combination of statistical inference and the theory of stochastic processes. Multi-State Survival Models for Interval-Censored Data shows that the statistical modelling is versatile and allows for a wide range of applications.

An Introduction to Stochastic Modeling

Author : Howard M. Taylor
Publisher : Academic Press
ISBN 13 : 1483269272
Total Pages : 410 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis An Introduction to Stochastic Modeling by : Howard M. Taylor

Download or read book An Introduction to Stochastic Modeling written by Howard M. Taylor and published by Academic Press. This book was released on 2014-05-10 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Stochastic Modeling provides information pertinent to the standard concepts and methods of stochastic modeling. This book presents the rich diversity of applications of stochastic processes in the sciences. Organized into nine chapters, this book begins with an overview of diverse types of stochastic models, which predicts a set of possible outcomes weighed by their likelihoods or probabilities. This text then provides exercises in the applications of simple stochastic analysis to appropriate problems. Other chapters consider the study of general functions of independent, identically distributed, nonnegative random variables representing the successive intervals between renewals. This book discusses as well the numerous examples of Markov branching processes that arise naturally in various scientific disciplines. The final chapter deals with queueing models, which aid the design process by predicting system performance. This book is a valuable resource for students of engineering and management science. Engineers will also find this book useful.

Competing Risks and Multistate Models with R

Author : Jan Beyersmann
Publisher : Springer Science & Business Media
ISBN 13 : 1461420350
Total Pages : 249 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Competing Risks and Multistate Models with R by : Jan Beyersmann

Download or read book Competing Risks and Multistate Models with R written by Jan Beyersmann and published by Springer Science & Business Media. This book was released on 2011-11-18 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers competing risks and multistate models, sometimes summarized as event history analysis. These models generalize the analysis of time to a single event (survival analysis) to analysing the timing of distinct terminal events (competing risks) and possible intermediate events (multistate models). Both R and multistate methods are promoted with a focus on nonparametric methods.

Modern Statistical Methods in Chronic Disease Epidemiology

Author : Suresh H. Moolgavkar
Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Modern Statistical Methods in Chronic Disease Epidemiology by : Suresh H. Moolgavkar

Download or read book Modern Statistical Methods in Chronic Disease Epidemiology written by Suresh H. Moolgavkar and published by Wiley-Interscience. This book was released on 1986-05-09 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a conference sponsored by the SIAM Institute for Mathematics and Society, and supported by the Department of Energy. Brings together recent developments in the statistical methodology for chronic disease epidimiology. The contributors are all at the forefront of biostatistics research.

Cost Effectiveness Modelling for Health Technology Assessment

Author : Richard Edlin
Publisher : Springer
ISBN 13 : 3319157442
Total Pages : 217 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Cost Effectiveness Modelling for Health Technology Assessment by : Richard Edlin

Download or read book Cost Effectiveness Modelling for Health Technology Assessment written by Richard Edlin and published by Springer. This book was released on 2015-08-11 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to decision analytic cost-effectiveness modelling, giving the theoretical and practical knowledge required to design and implement analyses that meet the methodological standards of health technology assessment organisations. The book guides you through building a decision tree and Markov model and, importantly, shows how the results of cost-effectiveness analyses are interpreted. Given the complex nature of cost-effectiveness modelling and the often unfamiliar language that runs alongside it, we wanted to make this book as accessible as possible whilst still providing a comprehensive, in-depth, practical guide that reflects the state of the art – that includes the most recent developments in cost-effectiveness modelling. Although the nature of cost effectiveness modelling means that some parts are inevitably quite technical, across the 13 chapters we have broken down explanations of theory and methods into bite-sized pieces that you can work through at your own pace; we have provided explanations of terms and methods as we use them. Importantly, the exercises and online workbooks allow you to test your skills and understanding as you go along.

Efficient Learning Machines

Author : Mariette Awad
Publisher : Apress
ISBN 13 : 1430259906
Total Pages : 263 pages
Book Rating : 4.4/5 (32 download)

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Book Synopsis Efficient Learning Machines by : Mariette Awad

Download or read book Efficient Learning Machines written by Mariette Awad and published by Apress. This book was released on 2015-04-27 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine learning techniques provide cost-effective alternatives to traditional methods for extracting underlying relationships between information and data and for predicting future events by processing existing information to train models. Efficient Learning Machines explores the major topics of machine learning, including knowledge discovery, classifications, genetic algorithms, neural networking, kernel methods, and biologically-inspired techniques. Mariette Awad and Rahul Khanna’s synthetic approach weaves together the theoretical exposition, design principles, and practical applications of efficient machine learning. Their experiential emphasis, expressed in their close analysis of sample algorithms throughout the book, aims to equip engineers, students of engineering, and system designers to design and create new and more efficient machine learning systems. Readers of Efficient Learning Machines will learn how to recognize and analyze the problems that machine learning technology can solve for them, how to implement and deploy standard solutions to sample problems, and how to design new systems and solutions. Advances in computing performance, storage, memory, unstructured information retrieval, and cloud computing have coevolved with a new generation of machine learning paradigms and big data analytics, which the authors present in the conceptual context of their traditional precursors. Awad and Khanna explore current developments in the deep learning techniques of deep neural networks, hierarchical temporal memory, and cortical algorithms. Nature suggests sophisticated learning techniques that deploy simple rules to generate highly intelligent and organized behaviors with adaptive, evolutionary, and distributed properties. The authors examine the most popular biologically-inspired algorithms, together with a sample application to distributed datacenter management. They also discuss machine learning techniques for addressing problems of multi-objective optimization in which solutions in real-world systems are constrained and evaluated based on how well they perform with respect to multiple objectives in aggregate. Two chapters on support vector machines and their extensions focus on recent improvements to the classification and regression techniques at the core of machine learning.

The SAGE Dictionary of Quantitative Management Research

Author : Luiz Moutinho
Publisher : SAGE Publications
ISBN 13 : 1412935296
Total Pages : 371 pages
Book Rating : 4.4/5 (129 download)

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Book Synopsis The SAGE Dictionary of Quantitative Management Research by : Luiz Moutinho

Download or read book The SAGE Dictionary of Quantitative Management Research written by Luiz Moutinho and published by SAGE Publications. This book was released on 2011-02-09 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electronic Inspection Copy available for instructors here A must-have reference resource for quantitative management researchers, the Dictionary contains over 100 entries covering the fundamentals of quantitative methodologies; covering both analysis and implementation and examples of use, as well as detailed graphics to aid understanding. Every entry features: -An introduction to the topic, -Key relevant features, -A worked example, -A concise summary and a selection of further reading suggestions -Cross-references to associated concepts within the dictionary

Survival and Event History Analysis

Author : Odd Aalen
Publisher : Springer Science & Business Media
ISBN 13 : 038768560X
Total Pages : 550 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis Survival and Event History Analysis by : Odd Aalen

Download or read book Survival and Event History Analysis written by Odd Aalen and published by Springer Science & Business Media. This book was released on 2008-09-16 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to bridge the gap between standard textbook models and a range of models where the dynamic structure of the data manifests itself fully. The common denominator of such models is stochastic processes. The authors show how counting processes, martingales, and stochastic integrals fit very nicely with censored data. Beginning with standard analyses such as Kaplan-Meier plots and Cox regression, the presentation progresses to the additive hazard model and recurrent event data. Stochastic processes are also used as natural models for individual frailty; they allow sensible interpretations of a number of surprising artifacts seen in population data. The stochastic process framework is naturally connected to causality. The authors show how dynamic path analyses can incorporate many modern causality ideas in a framework that takes the time aspect seriously. To make the material accessible to the reader, a large number of practical examples, mainly from medicine, are developed in detail. Stochastic processes are introduced in an intuitive and non-technical manner. The book is aimed at investigators who use event history methods and want a better understanding of the statistical concepts. It is suitable as a textbook for graduate courses in statistics and biostatistics.

Animal Movement

Author : Mevin B. Hooten
Publisher : CRC Press
ISBN 13 : 1466582154
Total Pages : 321 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Animal Movement by : Mevin B. Hooten

Download or read book Animal Movement written by Mevin B. Hooten and published by CRC Press. This book was released on 2017-03-16 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of animal movement has always been a key element in ecological science, because it is inherently linked to critical processes that scale from individuals to populations and communities to ecosystems. Rapid improvements in biotelemetry data collection and processing technology have given rise to a variety of statistical methods for characterizing animal movement. The book serves as a comprehensive reference for the types of statistical models used to study individual-based animal movement. Animal Movement is an essential reference for wildlife biologists, quantitative ecologists, and statisticians who seek a deeper understanding of modern animal movement models. A wide variety of modeling approaches are reconciled in the book using a consistent notation. Models are organized into groups based on how they treat the underlying spatio-temporal process of movement. Connections among approaches are highlighted to allow the reader to form a broader view of animal movement analysis and its associations with traditional spatial and temporal statistical modeling. After an initial overview examining the role that animal movement plays in ecology, a primer on spatial and temporal statistics provides a solid foundation for the remainder of the book. Each subsequent chapter outlines a fundamental type of statistical model utilized in the contemporary analysis of telemetry data for animal movement inference. Descriptions begin with basic traditional forms and sequentially build up to general classes of models in each category. Important background and technical details for each class of model are provided, including spatial point process models, discrete-time dynamic models, and continuous-time stochastic process models. The book also covers the essential elements for how to accommodate multiple sources of uncertainty, such as location error and latent behavior states. In addition to thorough descriptions of animal movement models, differences and connections are also emphasized to provide a broader perspective of approaches.

Secondary Analysis of Electronic Health Records

Author : MIT Critical Data
Publisher : Springer
ISBN 13 : 3319437429
Total Pages : 435 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Secondary Analysis of Electronic Health Records by : MIT Critical Data

Download or read book Secondary Analysis of Electronic Health Records written by MIT Critical Data and published by Springer. This book was released on 2016-09-09 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a “data desert” when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients.

Safety and Reliability Modeling and Its Applications

Author : Mangey Ram
Publisher : Elsevier
ISBN 13 : 0128233230
Total Pages : 431 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Safety and Reliability Modeling and Its Applications by : Mangey Ram

Download or read book Safety and Reliability Modeling and Its Applications written by Mangey Ram and published by Elsevier. This book was released on 2021-08-12 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Safety and Reliability Modeling and Its Applications combines work by leading researchers in engineering, statistics and mathematics who provide innovative methods and solutions for this fast-moving field. Safety and reliability analysis is one of the most multidimensional topics in engineering today. Its rapid development has created many opportunities and challenges for both industrialists and academics, while also completely changing the global design and systems engineering environment. As more modeling tasks can now be undertaken within a computer environment using simulation and virtual reality technologies, this book helps readers understand the number and variety of research studies focusing on this important topic. The book addresses these important recent developments, presenting new theoretical issues that were not previously presented in the literature, along with solutions to important practical problems and case studies that illustrate how to apply the methodology. Uses case studies from industry practice to explain innovative solutions to real world safety and reliability problems Addresses the full interdisciplinary range of topics that influence this complex field Provides brief introductions to important concepts, including stochastic reliability and Bayesian methods

Models in Environmental Regulatory Decision Making

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309110009
Total Pages : 286 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Models in Environmental Regulatory Decision Making by : National Research Council

Download or read book Models in Environmental Regulatory Decision Making written by National Research Council and published by National Academies Press. This book was released on 2007-08-25 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many regulations issued by the U.S. Environmental Protection Agency (EPA) are based on the results of computer models. Models help EPA explain environmental phenomena in settings where direct observations are limited or unavailable, and anticipate the effects of agency policies on the environment, human health and the economy. Given the critical role played by models, the EPA asked the National Research Council to assess scientific issues related to the agency's selection and use of models in its decisions. The book recommends a series of guidelines and principles for improving agency models and decision-making processes. The centerpiece of the book's recommended vision is a life-cycle approach to model evaluation which includes peer review, corroboration of results, and other activities. This will enhance the agency's ability to respond to requirements from a 2001 law on information quality and improve policy development and implementation.

Joint Models for Longitudinal and Time-to-Event Data

Author : Dimitris Rizopoulos
Publisher : CRC Press
ISBN 13 : 1439872864
Total Pages : 279 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Joint Models for Longitudinal and Time-to-Event Data by : Dimitris Rizopoulos

Download or read book Joint Models for Longitudinal and Time-to-Event Data written by Dimitris Rizopoulos and published by CRC Press. This book was released on 2012-06-22 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: In longitudinal studies it is often of interest to investigate how a marker that is repeatedly measured in time is associated with a time to an event of interest, e.g., prostate cancer studies where longitudinal PSA level measurements are collected in conjunction with the time-to-recurrence. Joint Models for Longitudinal and Time-to-Event Data: With Applications in R provides a full treatment of random effects joint models for longitudinal and time-to-event outcomes that can be utilized to analyze such data. The content is primarily explanatory, focusing on applications of joint modeling, but sufficient mathematical details are provided to facilitate understanding of the key features of these models. All illustrations put forward can be implemented in the R programming language via the freely available package JM written by the author. All the R code used in the book is available at: http://jmr.r-forge.r-project.org/

Models for Intensive Longitudinal Data

Author : Theodore A. Walls
Publisher : Oxford University Press
ISBN 13 : 0198038666
Total Pages : 311 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis Models for Intensive Longitudinal Data by : Theodore A. Walls

Download or read book Models for Intensive Longitudinal Data written by Theodore A. Walls and published by Oxford University Press. This book was released on 2006-01-19 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid technological advances in devices used for data collection have led to the emergence of a new class of longitudinal data: intensive longitudinal data (ILD). Behavioral scientific studies now frequently utilize handheld computers, beepers, web interfaces, and other technological tools for collecting many more data points over time than previously possible. Other protocols, such as those used in fMRI and monitoring of public safety, also produce ILD, hence the statistical models in this volume are applicable to a range of data. The volume features state-of-the-art statistical modeling strategies developed by leading statisticians and methodologists working on ILD in conjunction with behavioral scientists. Chapters present applications from across the behavioral and health sciences, including coverage of substantive topics such as stress, smoking cessation, alcohol use, traffic patterns, educational performance and intimacy. Models for Intensive Longitudinal Data (MILD) is designed for those who want to learn about advanced statistical models for intensive longitudinal data and for those with an interest in selecting and applying a given model. The chapters highlight issues of general concern in modeling these kinds of data, such as a focus on regulatory systems, issues of curve registration, variable frequency and spacing of measurements, complex multivariate patterns of change, and multiple independent series. The extraordinary breadth of coverage makes this an indispensable reference for principal investigators designing new studies that will introduce ILD, applied statisticians working on related models, and methodologists, graduate students, and applied analysts working in a range of fields. A companion Web site at www.oup.com/us/MILD contains program examples and documentation.

Analysis of Multivariate Survival Data

Author : Philip Hougaard
Publisher : Springer Science & Business Media
ISBN 13 : 1461213045
Total Pages : 559 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Analysis of Multivariate Survival Data by : Philip Hougaard

Download or read book Analysis of Multivariate Survival Data written by Philip Hougaard and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survival data or more general time-to-event data occur in many areas, including medicine, biology, engineering, economics, and demography, but previously standard methods have requested that all time variables are univariate and independent. This book extends the field by allowing for multivariate times. As the field is rather new, the concepts and the possible types of data are described in detail. Four different approaches to the analysis of such data are presented from an applied point of view.

Computational Systems Biology

Author : Andres Kriete
Publisher : Academic Press
ISBN 13 : 0124059384
Total Pages : 549 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Computational Systems Biology by : Andres Kriete

Download or read book Computational Systems Biology written by Andres Kriete and published by Academic Press. This book was released on 2013-11-26 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. - Logical information flow aids understanding of basic building blocks of life through disease phenotypes - Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns - Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation - Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.

The Application of Hidden Markov Models in Speech Recognition

Author : Mark Gales
Publisher : Now Publishers Inc
ISBN 13 : 1601981201
Total Pages : 125 pages
Book Rating : 4.6/5 (19 download)

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Book Synopsis The Application of Hidden Markov Models in Speech Recognition by : Mark Gales

Download or read book The Application of Hidden Markov Models in Speech Recognition written by Mark Gales and published by Now Publishers Inc. This book was released on 2008 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Application of Hidden Markov Models in Speech Recognition presents the core architecture of a HMM-based LVCSR system and proceeds to describe the various refinements which are needed to achieve state-of-the-art performance.