Mirnomics Microrna Biology And Computational Analysis

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MiRNomics

Author : Jens Allmer
Publisher :
ISBN 13 : 9781071611708
Total Pages : 442 pages
Book Rating : 4.6/5 (117 download)

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Book Synopsis MiRNomics by : Jens Allmer

Download or read book MiRNomics written by Jens Allmer and published by . This book was released on 2022 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition presents an up-to-date overview of the current state-of-the-art protocols and aims to put the miRNomics into a broader perspective. Chapters detail methods and techniques ranging from miRNA biogenesis, their biological function, computational analyses to their medical implications and applications. Written in the highly successful Methods in Molecular Biology series format, the miRNomics second edition chapters include introductions to their respective topics, application details for both the expert and non-expert reader and tips on troubleshooting and avoiding known pitfalls. Authoritative and accessible, miRNomics: MicroRNA Biology and Computational Analysis, Second Edition ensures successful results in the further study of this vital field.

miRNomics: MicroRNA Biology and Computational Analysis

Author : Malik Yousef
Publisher : Humana
ISBN 13 : 9781493962648
Total Pages : 0 pages
Book Rating : 4.9/5 (626 download)

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Book Synopsis miRNomics: MicroRNA Biology and Computational Analysis by : Malik Yousef

Download or read book miRNomics: MicroRNA Biology and Computational Analysis written by Malik Yousef and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In miRNomics: MicroRNA Biology and Computational Analysis, expert researchers in the field present an overview of the current state of the art and aim to put the respective areas of research into a larger perspective. These include methods and techniques ranging from miRNA biogenesis, their biological function, computational analyses to their medical implications and applications. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, miRNomics: MicroRNA Biology and Computational Analysis seeks to aid scientists in the further study into miRNA research and statistics.

MicroRNA Cancer Regulation

Author : Ulf Schmitz
Publisher : Springer Science & Business Media
ISBN 13 : 9400755902
Total Pages : 352 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis MicroRNA Cancer Regulation by : Ulf Schmitz

Download or read book MicroRNA Cancer Regulation written by Ulf Schmitz and published by Springer Science & Business Media. This book was released on 2013-02-03 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and applications, together with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. We are sure that the emergence of high-throughput quantitative techniques will make this integrative approach absolutely necessary in the near future. This book will be a resource for researchers starting out with cancer microRNA research, but is also intended for the experienced researcher who wants to incorporate concepts and tools from systems biology and bioinformatics into his work. Bioinformaticians and modellers are provided with a general perspective on microRNA biology in cancer, and the state-of-the-art in computational microRNA biology.

MiRNAs in MAPs Computational Analysis

Author : Swati Srivastava
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.2/5 (245 download)

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Book Synopsis MiRNAs in MAPs Computational Analysis by : Swati Srivastava

Download or read book MiRNAs in MAPs Computational Analysis written by Swati Srivastava and published by . This book was released on 2024-01-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "miRNAs in MAPs Computational Analysis" by Swati Srivastava is a comprehensive book that explores the role of miRNAs in gene expression regulation, plant growth, and development, with a particular focus on MAPs (Medicinal and Aromatic Plants). The book describes the computational methods and tools used for analyzing small RNAs, mRNA, and their targets, including target prediction, differential expression analysis, and next-generation sequencing. Data mining and machine learning techniques are also discussed, as well as bioinformatics tools for gene ontology and pathway analysis. The book covers the impact of miRNAs on plant stress responses, including abiotic and biotic stress, and provides an overview of miRNA biogenesis and the molecular machinery involved, such as Argonaute, Dicer, and Drosha. The use of small RNA sequencing and high-throughput screening methods for the study of miRNAs is also highlighted. In addition, the book explores the role of miRNAs in plant-microbe interactions and immunity, and discusses the use of system biology and network analysis to understand miRNA-mediated gene regulation. The book also covers RNA interference, post-transcriptional gene silencing, in situ hybridization, qRT-PCR, RNA sequencing, deep sequencing, expression profiling, small RNA libraries, differential expression, evolutionary conservation, functional analysis, and gene function prediction. Overall, "miRNAs in MAPs Computational Analysis" provides a comprehensive overview of miRNA-mediated gene regulation and the computational methods used to study it, making it an invaluable resource for researchers and students in the field of computational biology and plant science.

Advancement in Gene Set Analysis: Gaining Insight From High-throughput Data

Author : Farhad Maleki
Publisher : Frontiers Media SA
ISBN 13 : 2889764230
Total Pages : 195 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Advancement in Gene Set Analysis: Gaining Insight From High-throughput Data by : Farhad Maleki

Download or read book Advancement in Gene Set Analysis: Gaining Insight From High-throughput Data written by Farhad Maleki and published by Frontiers Media SA. This book was released on 2022-08-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stress Biology in Photosynthetic Organisms

Author : Arun Kumar Mishra
Publisher : Springer Nature
ISBN 13 : 981971883X
Total Pages : 414 pages
Book Rating : 4.8/5 (197 download)

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Book Synopsis Stress Biology in Photosynthetic Organisms by : Arun Kumar Mishra

Download or read book Stress Biology in Photosynthetic Organisms written by Arun Kumar Mishra and published by Springer Nature. This book was released on with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Omics in Horticultural Crops

Author : Gyana Ranjan Rout
Publisher : Academic Press
ISBN 13 : 0323899137
Total Pages : 664 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Omics in Horticultural Crops by : Gyana Ranjan Rout

Download or read book Omics in Horticultural Crops written by Gyana Ranjan Rout and published by Academic Press. This book was released on 2022-07-16 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Omics in Horticulture Crops presents a comprehensive view of germplasm diversity, genetic evolution, genomics, proteomics and transcriptomics of fruit crops (temperate, tropical and subtropical fruits, fruit nuts, berries), vegetables, tuberous crops, ornamental and floricultural crops and medicinal aromatic plants. Information covering phenomics, genetic diversity, phylogenetic studies, genome sequencing, and genome barcoding through the utilization of molecular markers plays an imperative role in the characterization and effective utilization of diverse germplasm are included in the book. This is a valuable reference for researchers and academics seeking to improve cultivar productivity through enhanced genetic diversity while also retaining optimal traits and protecting the growing environment. Highlights perspectives, progress and promises of -omics application Provides a systematic overview of origin, progenitor and domestication process as well as genetic insights Includes full range of horticultural crops

Bioinformatics in Rice Research

Author : Manoj Kumar Gupta
Publisher : Springer Nature
ISBN 13 : 9811639930
Total Pages : 609 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Bioinformatics in Rice Research by : Manoj Kumar Gupta

Download or read book Bioinformatics in Rice Research written by Manoj Kumar Gupta and published by Springer Nature. This book was released on 2021-09-24 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an up-to-date review of classic and advanced bioinformatics approaches and their utility in rice research. It summarizes databases and tools for analyzing DNA, proteins and gene expression profiles, mapping genetic variations, annotation of protein and RNA molecules, phylogenetic analysis, and pathway enrichment. In addition, it presents high-throughput technologies that are widely used to provide deep insights into the genetic architecture of important traits in the rice genome. The book subsequently discusses techniques for identifying RNA-protein, DNA-protein interactions, and molecular markers, including SNP and microsatellites, in the contexts of rice breeding and genetics. Lastly, it explores various tools that are used to identify and characterize non-coding RNA in rice and their potential role in rice research.

MicroRNA in Human Infectious Diseases

Author : Vijay Kumar Prajapati
Publisher : Elsevier
ISBN 13 : 0323996620
Total Pages : 346 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis MicroRNA in Human Infectious Diseases by : Vijay Kumar Prajapati

Download or read book MicroRNA in Human Infectious Diseases written by Vijay Kumar Prajapati and published by Elsevier. This book was released on 2024-01-23 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNA in Human Infectious Diseases offers a detailed overview of the therapeutic and diagnostic role microRNAs can play in the treatment of various infectious diseases. Beginning with an introduction on microRNAs and their mechanisms, the book then delves into the therapeutic role of microRNAs in various categories of diseases: bacterial, viral, and parasitic. A wide range of diseases are explored in these sections, including sexually transmitted diseases, typhoid, tuberculosis, Dengue fever, Ebola, Covid-19, Malaria, Leishmaniasis, and Lymphatic filariasis. The final section of the book covers microRNA-based system approaches, considering aspects such as web-based tools available for detecting and predicting microRNA targets, and the latest technologies for modifying and manipulating microRNAs. This volume explores microRNA across a multitude of conditions and is an ideal reference for those involved in the investigation and development of treatments in this area. Includes foundational knowledge on microRNAs and the fundamental aspects of its biogenesis Explores the potential role microRNAs can play in therapeutics and diagnostics to treat various infectious diseases, including sexually-transmitted diseases, bacterial diseases, viral infections, and parasitic diseases Features a chapter dedicated to the role of microRNA for therapeutics in respiratory viral infections, such as Covid-19 Considers technologies used for manipulating and modifying microRNAs in preparation for applications to treat infectious diseases

Plant Small RNA

Author : Praveen Guleria
Publisher : Academic Press
ISBN 13 : 012817336X
Total Pages : 638 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Plant Small RNA by : Praveen Guleria

Download or read book Plant Small RNA written by Praveen Guleria and published by Academic Press. This book was released on 2020-02-19 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Small RNA: Biogenesis, Regulation and Application describes the biosynthesis of small RNA in plant systems. With an emphasis on the various molecular mechanisms affected by small RNA and their applications in supporting plant growth and survival, this books presents the basics and most recent advancements in small RNA mediated plant genomics, metabolomics, proteomics and physiology. In addition, it emphasizes the various molecular mechanisms affected by small RNA and their applications in supporting plant growth and survival. Final sections cover the most recent advancements in small RNA mediated plant genomics, metabolomics, proteomics and physiology. Presents foundational information about small RNA biology and regulation in plants Includes small RNA pathway advances Describes the application and scope of small RNA technology for agricultural stability

Multimodal Affective Computing

Author : Ramón Zatarain Cabada
Publisher : Springer Nature
ISBN 13 : 3031325427
Total Pages : 211 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Multimodal Affective Computing by : Ramón Zatarain Cabada

Download or read book Multimodal Affective Computing written by Ramón Zatarain Cabada and published by Springer Nature. This book was released on 2023-06-26 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores AI methodologies for the implementation of affective states in intelligent learning environments. Divided into four parts, Multimodal Affective Computing: Technologies and Applications in Learning Environments begins with an overview of Affective Computing and Intelligent Learning Environments, from their fundamentals and essential theoretical support up to their fusion and some successful practical applications. The basic concepts of Affective Computing, Machine Learning, and Pattern Recognition in Affective Computing, and Affective Learning Environments are presented in a comprehensive and easy-to-read manner. In the second part, a review on the emerging field of Sentiment Analysis for Learning Environments is introduced, including a systematic descriptive tour through topics such as building resources for sentiment detection, methods for data representation, designing and testing the classification models, and model integration into a learning system. The methodologies corresponding to Multimodal Recognition of Learning-Oriented Emotions are presented in the third part of the book, where topics such as building resources for emotion detection, methods for data representation, multimodal recognition systems, and multimodal emotion recognition in learning environments are presented. The fourth and last part of the book is devoted to a wide application field of the combination of methodologies, such as Automatic Personality Recognition, dealing with issues such as building resources for personality recognition, methods for data representation, personality recognition models, and multimodal personality recognition for affective computing. This book can be very useful not only for beginners who are interested in affective computing and intelligent learning environments, but also for advanced and experts in the practice and developments of the field. It complies an end-to-end treatment on these subjects, especially with educational applications, making it easy for researchers and students to get on track with fundamentals, established methodologies, conventional evaluation protocols, and the latest progress on these subjects.

Advanced AI Techniques and Applications in Bioinformatics

Author : Loveleen Gaur
Publisher : CRC Press
ISBN 13 : 1000462986
Total Pages : 282 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Advanced AI Techniques and Applications in Bioinformatics by : Loveleen Gaur

Download or read book Advanced AI Techniques and Applications in Bioinformatics written by Loveleen Gaur and published by CRC Press. This book was released on 2021-10-18 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advanced AI techniques are essential for resolving various problematic aspects emerging in the field of bioinformatics. This book covers the recent approaches in artificial intelligence and machine learning methods and their applications in Genome and Gene editing, cancer drug discovery classification, and the protein folding algorithms among others. Deep learning, which is widely used in image processing, is also applicable in bioinformatics as one of the most popular artificial intelligence approaches. The wide range of applications discussed in this book are an indispensable resource for computer scientists, engineers, biologists, mathematicians, physicians, and medical informaticists. Features: Focusses on the cross-disciplinary relation between computer science and biology and the role of machine learning methods in resolving complex problems in bioinformatics Provides a comprehensive and balanced blend of topics and applications using various advanced algorithms Presents cutting-edge research methodologies in the area of AI methods when applied to bioinformatics and innovative solutions Discusses the AI/ML techniques, their use, and their potential for use in common and future bioinformatics applications Includes recent achievements in AI and bioinformatics contributed by a global team of researchers

Exosomes and MicroRNAs in Biomedical Science

Author : Hamed Mirzaei
Publisher : Springer Nature
ISBN 13 : 3031791770
Total Pages : 171 pages
Book Rating : 4.0/5 (317 download)

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Book Synopsis Exosomes and MicroRNAs in Biomedical Science by : Hamed Mirzaei

Download or read book Exosomes and MicroRNAs in Biomedical Science written by Hamed Mirzaei and published by Springer Nature. This book was released on 2022-06-06 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNAs (miRNAs) are a member of the family of non-coding RNA molecules, and consist of small conserved sequences between 19–25 nucleotides in length that are responsible for regulating many cellular functions by affecting a wide range of messenger RNAs in a sequence specific manner. Fundamental biological processes like cell proliferation and growth, stress resistance, tumorigenesis, fat metabolism, and neural development have all been shown to be governed by miRNAs. miRNAs carry out the post-transcriptional silencing of gene expression via targeting the 30-untranslated region (UTR) of the complementary mRNA sequence. The dysregulation of the expression levels of various miRNAs is typical of tumor cells, and has been associated with tumor progression and poor prognosis. Many miRNAs are up-regulated in cancer, where they can silence tumor suppressor genes such as apoptosis and immune response associated genes. Therefore, it is possible to profile the expression levels of miRNAs as biomarkers, in order to diagnose cancer and noncancerous diseases. Moreover, cancer detection in the early stages is crucial in clinical situations. Characterization of miRNAs in serum, plasma, and other bodily fluids, and understanding their stability against RNase degradation, is important to assess their suitability as biomarkers and diagnostic tools. Exosomes play an important role in inter-cellular communications, and these nanosized particles have various functions in diverse physiological pathways, in normal as well as abnormal cells. Exosomes can carry diverse cargos such as mRNAs, miRNAs, and proteins that transfer information between donor and recipient cells. Furthermore, uptake of exosomes and their cargos may promote or suppress various molecular and cellular pathways, which alter the cellular behavior. Many reports have discussed the role of exosomes released from cancer cells on the progression of cancer at various stages. Exosomes and their cargos may affect the growth of the tumor, metastasis, drug resistance, immune system function, as well as angiogenesis. Therefore, exosomes have been explored as diagnostic biomarkers in many cancers. Moreover, exosomes can be used as biological vehicles to deliver different drugs and agents like doxorubicin (DOX), miRNAs, and siRNAs. The present book covers the role of exosomes and micro-RNAs in the pathogenesis and treatment of various diseases.

Database and Expert Systems Applications

Author : Gabriele Anderst-Kotsis
Publisher : Springer
ISBN 13 : 3030276848
Total Pages : 230 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Database and Expert Systems Applications by : Gabriele Anderst-Kotsis

Download or read book Database and Expert Systems Applications written by Gabriele Anderst-Kotsis and published by Springer. This book was released on 2019-08-19 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume constitutes the refereed proceedings of the four workshops held at the 30th International Conference on Database and Expert Systems Applications, DEXA 2019, held in Linz, Austria, in August 2019: The 10th International Workshop on Biological Knowledge Discovery from Data, BIOKDD 2019, the 3rd International Workshop on Cyber-Security and Functional Safety in Cyber-Physical Systems, IWCFS 2019, the 1st International Workshop on Machine Learning and Knowledge Graphs, MLKgraphs2019, and the 16th International Workshop on Technologies for Information Retrieval, TIR 2019. The 26 selected papers discuss a range of topics including: knowledge discovery, biological data, cyber security, cyber-physical system, machine learning, knowledge graphs, information retriever, data base, and artificial intelligent.

Epigenetics in Plants of Agronomic Importance: Fundamentals and Applications

Author : Raúl Alvarez-Venegas
Publisher : Springer
ISBN 13 : 3030147606
Total Pages : 415 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Epigenetics in Plants of Agronomic Importance: Fundamentals and Applications by : Raúl Alvarez-Venegas

Download or read book Epigenetics in Plants of Agronomic Importance: Fundamentals and Applications written by Raúl Alvarez-Venegas and published by Springer. This book was released on 2019-04-26 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few decades, chromatin modulation has emerged as an important regulator of gene expression. This second edition provides detailed information on the epigenetic mechanisms in plants, illustrating the value of this research in plants of agronomic importance. It examines recent advances regarding plants’ epigenetic regulation in response to abiotic and biotic types of stress; the epigenetic basis of plant immunity; evolution and functions of plant histones; epigenetic variation and plant breeding; and epigenome editing and crop improvement. The content is intended to promote the development of future biotechnologies to manipulate and selectively activate/inhibit proteins and metabolic pathways to counter pathogens, to treat important diseases, and to increase crop productivity. The development of new fields, like epigenome editing and RNA epigenetics, will certainly improve our understanding of currently known epigenetic modifications and their roles in e.g. host-pathogen interactions, crop productivity, and in response to environmental stimuli. This volume contains twelve new/revised chapters, written by an international team of experts on plant epigenetics, and addresses the needs of researchers and professionals in the fields of agronomics, crop breeding, epigenetics, plant biochemistry, plant developmental biology, and related disciplines.

Autophagy in tumor and tumor microenvironment

Author : Sujit Kumar Bhutia
Publisher : Springer Nature
ISBN 13 : 9811569304
Total Pages : 284 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Autophagy in tumor and tumor microenvironment by : Sujit Kumar Bhutia

Download or read book Autophagy in tumor and tumor microenvironment written by Sujit Kumar Bhutia and published by Springer Nature. This book was released on 2020-10-24 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent roles in tumors; accordingly, strategies based on inhibiting or stimulating autophagy could offer as potential cancer therapies. The book elucidates the physiological role of autophagy in modulating cancer metastasis, which is the primary cause of cancer-associated mortality. Further, it reviews its role in the differentiation, development, and activation of multiple immune cells, and its potential applications in tumor immunotherapy. In addition, it examines the effect of epigenetic modifications of autophagy-associated genes in regulating tumor growth and therapeutic response and summarizes autophagy’s role in the development of resistance to a variety of anti-cancer drugs in cancer cells. In closing, it assesses autophagy as a potential therapeutic target for cancer treatment. Given its scope, the book offers a valuable asset for all oncologists and researchers who wish to understand the potential role of autophagy in tumor biology.

Bioinformatics Tools for Pharmaceutical Drug Product Development

Author : Vivek Chavda
Publisher : John Wiley & Sons
ISBN 13 : 1119865700
Total Pages : 452 pages
Book Rating : 4.1/5 (198 download)

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Book Synopsis Bioinformatics Tools for Pharmaceutical Drug Product Development by : Vivek Chavda

Download or read book Bioinformatics Tools for Pharmaceutical Drug Product Development written by Vivek Chavda and published by John Wiley & Sons. This book was released on 2023-02-09 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: BIOINFORMATICS TOOLS FOR Pharmaceutical DRUG PRODUCT DLEVELOPMENT A timely book that details bioinformatics tools, artificial intelligence, machine learning, computational methods, protein interactions, peptide-based drug design, and omics technologies, for drug development in the pharmaceutical and medical sciences industries. The book contains 17 chapters categorized into 3 sections. The first section presents the latest information on bioinformatics tools, artificial intelligence, machine learning, computational methods, protein interactions, peptide-based drug design, and omics technologies. The following 2 sections include bioinformatics tools for the pharmaceutical sector and the healthcare sector. Bioinformatics brings a new era in research to accelerate drug target and vaccine design development, improving validation approaches as well as facilitating and identifying side effects and predicting drug resistance. As such, this will aid in more successful drug candidates from discovery to clinical trials to the market, and most importantly make it a more cost-effective process overall. Readers will find in this book: Applications of bioinformatics tools for pharmaceutical drug product development like process development, pre-clinical development, clinical development, commercialization of the product, etc.; The ever-expanding application of this novel technology and discusses some of the unique challenges associated with such an approach; The broad and deep background, as well as updates, on recent advances in both medicine and AI/ML that enable the application of these cutting-edge bioinformatics tools. Audience The book will be used by researchers and scientists in academia and industry including drug developers, computational biochemists, bioinformaticians, immunologists, pharmaceutical and medical sciences, as well as those in artificial intelligence and machine learning.