Microtechnology for Cell Manipulation and Sorting

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Author :
Publisher : Springer
ISBN 13 : 3319441396
Total Pages : 281 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Microtechnology for Cell Manipulation and Sorting by : Wonhee Lee

Download or read book Microtechnology for Cell Manipulation and Sorting written by Wonhee Lee and published by Springer. This book was released on 2016-10-05 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book delves into the recent developments in the microscale and microfluidic technologies that allow manipulation at the single and cell aggregate level. Expert authors review the dominant mechanisms that manipulate and sort biological structures, making this a state-of-the-art overview of conventional cell sorting techniques, the principles of microfluidics, and of microfluidic devices. All chapters highlight the benefits and drawbacks of each technique they discuss, which include magnetic, electrical, optical, acoustic, gravity/sedimentation, inertial, deformability, and aqueous two-phase systems as the dominant mechanisms utilized by microfluidic devices to handle biological samples. Each chapter explains the physics of the mechanism at work, and reviews common geometries and devices to help readers decide the type of style of device required for various applications. This book is appropriate for graduate-level biomedical engineering and analytical chemistry students, as well as engineers and scientists working in the biotechnology industry.

Microfluidic Cell Culture Systems

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Author :
Publisher : Elsevier
ISBN 13 : 0128136723
Total Pages : 396 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Microfluidic Cell Culture Systems by : Jeffrey T Borenstein

Download or read book Microfluidic Cell Culture Systems written by Jeffrey T Borenstein and published by Elsevier. This book was released on 2018-09-12 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Techniques for microfabricating intricate microfluidic structures that mimic the microenvironment of tissues and organs, combined with the development of biomaterials with carefully engineered surface properties, have enabled new paradigms in and cell culture-based models for human diseases. The dimensions of surface features and fluidic channels made accessible by these techniques are well-suited to the size scale of biological cells. Microfluidic Cell Culture Systems applies design and experimental techniques used in in microfluidics, and cell culture technologies to organ-on-chip systems. This book is intended to serve as a professional reference, providing a practical guide to design and fabrication of microfluidic systems and biomaterials for use in cell culture systems and human organ models. The book covers topics ranging from academic first principles of microfluidic design, to clinical translation strategies for cell culture protocols. The goal is to help professionals coming from an engineering background to adapt their expertise for use in cell culture and organ models applications, and likewise to help biologists to design and employ microfluidic technologies in their cell culture systems. This 2nd edition contains new material that strengthens the focus on in vitro models useful for drug discovery and development. One new chapter reviews liver organ models from an industry perspective, while others cover new technologies for scaling these models and for multi-organ systems. Other new chapters highlight the development of organ models and systems for specific applications in disease modeling and drug safety. Previous chapters have been revised to reflect the latest advances. Provides design and operation methodology for microfluidic and microfabricated materials and devices for organ-on-chip disease and safety models. This is a rapidly expanding field that will continue to grow along with advances in cell biology and microfluidics technologies. Comprehensively covers strategies and techniques ranging from academic first principles to industrial scale-up approaches. Readers will gain insight into cell-material interactions, microfluidic flow, and design principles. Offers three fundamental types of information: 1) design principles, 2) operation techniques, and 3) background information/perspectives. The book is carefully designed to strike a balance between these three areas, so it will be of use to a broad range of readers with different technical interests and educational levels.

Medical and Industrial Applications of Microfluidic-based Cell/Tissue Culture and Organs-on-a-Chip: Advances in Organs-on-a-Chip and Organoids Technologies

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889631141
Total Pages : 138 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Medical and Industrial Applications of Microfluidic-based Cell/Tissue Culture and Organs-on-a-Chip: Advances in Organs-on-a-Chip and Organoids Technologies by : Qasem Ramadan

Download or read book Medical and Industrial Applications of Microfluidic-based Cell/Tissue Culture and Organs-on-a-Chip: Advances in Organs-on-a-Chip and Organoids Technologies written by Qasem Ramadan and published by Frontiers Media SA. This book was released on 2019-10-16 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments in microfluidics have demonstrated enormous potential of microscale cell culture for biology studies and recognized as instrumental in performing rapid and efficient experiments on small-sample volumes. Microfluidic-based cell culture is an area of research that keeps growing and gaining importance as a prominent technology, able to link scientific disciplines with industrial and clinical applications. In particular, organotypic cell culture and its integration in microfluidic devices would enable the realization of “in vivo-like” cell microenvironment within systems that are more amenable to automation and integration. Such remarkable advancement forms the foundation and motivation to transfer research from the laboratory to the field. Although the microfluidics and cell culture technologies have influenced many areas of science, significant research efforts are currently focus on finding methods to transform drug screening and toxicity testing from a system reliant on high-dose animal studies to one based primarily on human-relevant in vitro models. In line with regulatory developments precluding the use of animal testing, as well as fundamental differences in animal versus human, human in vitro methodologies are required to replace the animal-based testes while permitting physiologically relevant model equivalents for superior prediction. Organs-on-a-chip is an ambitious and rapidly growing technology that promise to bridge the gap between in vivo and in vitro studies and open wide possibilities in medical and industrial applications. However, many challenges are still ahead. This eBook present recent state-of-the-art works and critical reviews in organs-on-a-chip technology which highlight the new advances in this growing field with an emphasis on the interface between technological advancements and high impact applications.

Particles Separation in Microfluidic Devices

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Author :
Publisher : MDPI
ISBN 13 : 3039366947
Total Pages : 230 pages
Book Rating : 4.0/5 (393 download)

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Book Synopsis Particles Separation in Microfluidic Devices by : Takasi Nisisako

Download or read book Particles Separation in Microfluidic Devices written by Takasi Nisisako and published by MDPI. This book was released on 2020-12-10 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidic platforms are increasingly being used for separating a wide variety of particles based on their physical and chemical properties. In the past two decades, many practical applications have been found in chemical and biological sciences, including single cell analysis, clinical diagnostics, regenerative medicine, nanomaterials synthesis, environmental monitoring, etc. In this Special Issue, we invited contributions to report state-of-the art developments in the fields of micro- and nanofluidic separation, fractionation, sorting, and purification of all classes of particles, including, but not limited to, active devices using electric, magnetic, optical, and acoustic forces; passive devices using geometries and hydrodynamic effects at the micro/nanoscale; confined and open platforms; label-based and label-free technology; and separation of bioparticles (including blood cells), circulating tumor cells, live/dead cells, exosomes, DNA, and non-bioparticles, including polymeric or inorganic micro- and nanoparticles, droplets, bubbles, etc. Practical devices that demonstrate capabilities to solve real-world problems were of particular interest.

Pulsed Electric Fields Technology for the Food Industry

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Author :
Publisher : Springer Nature
ISBN 13 : 3030705862
Total Pages : 558 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Pulsed Electric Fields Technology for the Food Industry by : Javier Raso

Download or read book Pulsed Electric Fields Technology for the Food Industry written by Javier Raso and published by Springer Nature. This book was released on 2022-01-01 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many novel technologies have been proposed in the attempt to improve existing food processing methods. Among emerging nonthermal technologies, high intensity pulsed electric fields (PEF) is appealing due to its short treatment times and reduced heating effects. This book presents information accumulated on PEF during the last 15 years by experienced microbiologists, biochemists, food technologists, and electrical and food engineers.

Microfluidics for Cells and Other Organisms

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Author :
Publisher : MDPI
ISBN 13 : 3039215620
Total Pages : 200 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Microfluidics for Cells and Other Organisms by : Danny van Noort

Download or read book Microfluidics for Cells and Other Organisms written by Danny van Noort and published by MDPI. This book was released on 2019-10-23 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics-based devices play an important role in creating realistic microenvironments in which cell cultures can thrive. They can, for example, be used to monitor drug toxicity and perform medical diagnostics, and be in a static-, perfusion- or droplet-based device. They can also be used to study cell-cell, cell-matrix or cell-surface interactions. Cells can be either single cells, 3D cell cultures or co-cultures. Other organisms could include bacteria, zebra fish embryo, C. elegans, to name a few.

Processing of Foods and Biomass Feedstocks by Pulsed Electric Energy

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Author :
Publisher : Springer Nature
ISBN 13 : 3030409171
Total Pages : 422 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Processing of Foods and Biomass Feedstocks by Pulsed Electric Energy by : Eugene Vorobiev

Download or read book Processing of Foods and Biomass Feedstocks by Pulsed Electric Energy written by Eugene Vorobiev and published by Springer Nature. This book was released on 2020-04-10 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive range of research on pulsed electric energy used in food processing, including sections on the fundamentals of electroporation and important techniques for the estimation of electroporation effects in various foods and biomass feedstocks. By focusing on application over theory, this book presents researchers with practical steps for processing techniques such as solid-liquid extraction, pressing, osmotic dehydration, drying, freezing and cooking. Special interest is given to the selective recovery and extraction of sugar, inulin, starch, proteins, polysaccharides, polyphenols, pigments, flavor compounds, phytochemicals and other of high-value components from food biomasses such as fruits and vegetables, leaves, herbs, mushrooms, microalgae and suspensions of cells. Processing of Foods and Biomass Feedstocks by Pulsed Electric Energy presents a singular overview of the biorefinery applications of pulsed electric energy for the processing of wastes and non-food biomasses such as root and tuber crops, grape waste, lignocellulosic biomass, oil crops and residues and seeds and peels of exotic and citrus fruits. The book begins by presenting general information on the fundamentals of electroporation and information on the procedures and protocols involved. Further chapters focus on the specific food processing operations involved and biorefinery applications for the processing of wastes and non-food biomasses. All of the relevant and up-to-date information any researcher needs on pulsed electric energy in food processing is presented here in this text.

Nonmagnetic and Magnetic Quantum Dots

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535139592
Total Pages : 248 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Nonmagnetic and Magnetic Quantum Dots by : Vasilios N. Stavrou

Download or read book Nonmagnetic and Magnetic Quantum Dots written by Vasilios N. Stavrou and published by BoD – Books on Demand. This book was released on 2018-04-04 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book entitled Nonmagnetic and Magnetic Quantum Dots is divided into two sections. In Section 1, the chapters are related to nonmagnetic quantum dots and their applications. More specifically, exact models and numerical methods have been presented to describe the analytical solution of the carrier wave functions, the quantum mechanical aspects of quantum dots, and the comparison of the latter to experimental data. Furthermore, methods to produce quantum dots, synthesis techniques of colloidal quantum dots, and applications on sensors and biology, among others, are included in this section. In Section 2, a few topics of magnetic quantum dots and their applications are presented. The section starts with a theoretical model to describe the magnetization dynamics in magnetic quantum dot array and the description of dilute magnetic semiconducting quantum dots and their applications. Additionally, a few applications of magnetic quantum dots in sensors, biology, and medicine are included in Section 2.

Microfluidics for Single-Cell Analysis

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Author :
Publisher : Springer Nature
ISBN 13 : 9813297298
Total Pages : 261 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Microfluidics for Single-Cell Analysis by : Jin-Ming Lin

Download or read book Microfluidics for Single-Cell Analysis written by Jin-Ming Lin and published by Springer Nature. This book was released on 2019-08-28 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the various microfluidic-based approaches for single-cell capture, isolation, manipulation, culture and observation, lysis, and analysis. Single-cell analysis reveals the heterogeneities in morphology, functions, composition, and genetic performance of seemingly identical cells, and advances in single-cell analysis can overcome the difficulties arising due to cell heterogeneity in the diagnostics for a targeted model of disease. This book provides a detailed review of the state-of-the-art techniques presenting the pros and cons of each of these methods. It also offers lessons learned and tips from front-line investigators to help researchers overcome bottlenecks in their own studies. Highlighting a number of techniques, such as microfluidic droplet techniques, combined microfluidics-mass-spectrometry systems, and nanochannel sampling, it describes in detail a new microfluidic chip-based live single-cell extractor (LSCE) developed in the editor’s laboratory, which opens up new avenues to use open microfluidics in single-cell extraction, single-cell mass spectrometric analysis, single-cell adhesion analysis and subcellular operations. Serving as both an elementary introduction and advanced guidebook, this book interests and inspires scholars and students who are currently studying or wish to study microfluidics-based cell analysis methods.

Imaging Technologies and Transdermal Delivery in Skin Disorders

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Publisher : John Wiley & Sons
ISBN 13 : 3527344608
Total Pages : 498 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Imaging Technologies and Transdermal Delivery in Skin Disorders by : Chenjie Xu

Download or read book Imaging Technologies and Transdermal Delivery in Skin Disorders written by Chenjie Xu and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the latest information on imaging technologies and transdermal delivery in skin disorders This important, timely book covers the latest understanding about today's major skin disorders, the development of imaging technologies for skin diagnosis, and the applications of micro/nano-technologies for the treatment of skin complications. It also places great emphasis on the critical role that interdisciplinary science occupies to achieve the requisite level of understanding of skin conditions and their management, which is essential to creating technologies that work. Imaging Technologies and Transdermal Delivery in Skin Disorders starts by outlining the structural characteristics of skin and skin appendages. It then discusses the key pathways involved in skin growth and development. Clinical presentations, pathophysiological mechanisms, and current clinical practices used to treat diseases affecting the skin are then introduced. Common preclinical models used for studying the mechanisms of diverse skin diseases, validation of novel therapeutic targets, and screening of new drugs to treat these diseases are also covered. The book examines the latest imaging technologies for understanding in vivo skin changes, as well as technologies such as high-resolution ultrasound imaging, quantitative Magnetic Resonance Imaging, high-resolution Optical Coherence Tomography, and emerging hybrid-imaging modalities. It concludes with chapters introducing emerging drug delivery technologies and potential future innovative developments. * Presents up-to-date knowledge of the skin biology and pathologies * Introduces advancements in the topic of imaging technology for tracing the drug delivery process, which is rarely systematically reported by other counterparts * Covers the latest development in three inter-related directions of drug delivery, imaging, and skin disease intersect for skin research * Provides an overview of the latest development of diagnostic and therapeutic technologies for skin diseases Imaging Technologies and Transdermal Delivery in Skin Disorders will be of great interest to analytical chemists, materials scientists, pharmaceutical chemists, clinical chemists, biotechnologists, bioengineers, cosmetics industry, and dermatologists.

Handbook on Biological Warfare Preparedness

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Publisher : Academic Press
ISBN 13 : 012812055X
Total Pages : 306 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Handbook on Biological Warfare Preparedness by : S.J.S. Flora

Download or read book Handbook on Biological Warfare Preparedness written by S.J.S. Flora and published by Academic Press. This book was released on 2019-10-05 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook on Biological Warfare Preparedness provides detailed information on biological warfare agents and their mode of transmission and spread. In addition, it explains methods of detection and medical countermeasures, including vaccine and post-exposure therapeutics, with specific sections detailing diseases, their transmission, clinical signs and symptoms, diagnosis, treatment, vaccines, prevention and management. This book is useful reading for researchers and advanced students in toxicology, but it will also prove helpful for medical students, civil administration, medical doctors, first responders and security forces. As the highly unpredictable nature of any event involving biological warfare agents has given rise to the need for the rapid development of accurate detection systems, this book is a timely resource on the topic. Introduces different bacterial and viral agents, including Ebola and other emerging threats and toxins Discusses medical countermeasures, including vaccines and post-exposure therapeutics Includes a comprehensive review of current methods of detection

Microdevices and Microsystems for Cell Manipulation

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Author :
Publisher : MDPI
ISBN 13 : 3038426180
Total Pages : 179 pages
Book Rating : 4.0/5 (384 download)

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Book Synopsis Microdevices and Microsystems for Cell Manipulation by : Aaron T. Ohta

Download or read book Microdevices and Microsystems for Cell Manipulation written by Aaron T. Ohta and published by MDPI. This book was released on 2018-07-03 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Microdevices and Microsystems for Cell Manipulation" that was published in Micromachines

Cell Separation Methods and Applications

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Publisher : CRC Press
ISBN 13 : 1482273640
Total Pages : 352 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Cell Separation Methods and Applications by : Diether Recktenwald

Download or read book Cell Separation Methods and Applications written by Diether Recktenwald and published by CRC Press. This book was released on 1997-11-04 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Offers complete coverage and assessment of cell separation technologies for analytical and preparative isolations of biological cell populations-demonstrating how to select and devise optimal sorting strategies for applications in biochemistry, immunology, cell and molecular biology, and clinical research. "

Essentials of Single-Cell Analysis

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Author :
Publisher : Springer
ISBN 13 : 3662491184
Total Pages : 414 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Essentials of Single-Cell Analysis by : Fan-Gang Tseng

Download or read book Essentials of Single-Cell Analysis written by Fan-Gang Tseng and published by Springer. This book was released on 2016-01-21 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of single-cell isolation, separation, injection, lysis and dynamics analysis as well as a study of their heterogeneity using different miniaturized devices. As an important part of single-cell analysis, different techniques including electroporation, microinjection, optical trapping, optoporation, rapid electrokinetic patterning and optoelectronic tweezers are described in detail. It presents different fluidic systems (e.g. continuous micro/nano-fluidic devices, microfluidic cytometry) and their integration with sensor technology, optical and hydrodynamic stretchers etc., and demonstrates the applications of single-cell analysis in systems biology, proteomics, genomics, epigenomics, cancer transcriptomics, metabolomics, biomedicine and drug delivery systems. It also discusses the future challenges for single-cell analysis, including the advantages and limitations. This book is enjoyable reading material while at the same time providing essential information to scientists in academia and professionals in industry working on different aspects of single-cell analysis. Dr. Fan-Gang Tseng is a Distinguished Professor of Engineering and System Science at the National Tsing Hua University, Taiwan. Dr. Tuhin Subhra Santra is a Research Associate at the California Nano Systems Institute, University of California at Los Angeles, USA.

Engineering of Micro/Nano Biosystems

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Author :
Publisher : Springer
ISBN 13 : 9811365490
Total Pages : 368 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Engineering of Micro/Nano Biosystems by : Gregory Barbillon

Download or read book Engineering of Micro/Nano Biosystems written by Gregory Barbillon and published by Springer. This book was released on 2019-08-02 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This tutorial book offers an in-depth overview of the fundamental principles of micro/nano technologies and devices related to sensing, actuation and diagnosis in fluidics and biosystems. Research in the MEMS/NEMS and lab-on-chip fields has seen rapid growth in both academic and industrial domains, as these biodevices and systems are increasingly replacing traditional large size diagnostic tools. This book is unique in describing not only the devices and technologies but also the basic principles of their operation. The comprehensive description of the fabrication, packaging and principles of micro/nano biosystems presented in this book offers guidance for researchers designing and implementing these biosystems across diverse fields including medical, pharmaceutical and biological sciences. The book provides a detailed overview of the fundamental mechanical, optical, electrical and magnetic principles involved, together with the technologies required for the design, fabrication and characterization of micro/nano fluidic systems and bio-devices. Written by a collaborative team from France and Korea, the book is suitable for academics, researchers, advanced level students and industrial manufacturers.

Optical Nano and Micro Actuator Technology

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Author :
Publisher : CRC Press
ISBN 13 : 1439840547
Total Pages : 666 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Optical Nano and Micro Actuator Technology by : George K. Knopf

Download or read book Optical Nano and Micro Actuator Technology written by George K. Knopf and published by CRC Press. This book was released on 2017-12-19 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Optical Nano and Micro Actuator Technology, leading engineers, material scientists, chemists, physicists, laser scientists, and manufacturing specialists offer an in-depth, wide-ranging look at the fundamental and unique characteristics of light-driven optical actuators. They discuss how light can initiate physical movement and control a variety of mechanisms that perform mechanical work at the micro- and nanoscale. The book begins with the scientific background necessary for understanding light-driven systems, discussing the nature of light and the interaction between light and NEMS/MEMS devices. It then covers innovative optical actuator technologies that have been developed for many applications. The book examines photoresponsive materials that enable the design of optically driven structures and mechanisms and describes specific light-driven technologies that permit the manipulation of micro- and nanoscale objects. It also explores applications in optofluidics, bioMEMS and biophotonics, medical device design, and micromachine control. Inspiring the next generation of scientists and engineers to advance light-driven technologies, this book gives readers a solid grounding in this emerging interdisciplinary area. It thoroughly explains the scientific language and fundamental principles, provides a holistic view of optical nano and micro actuator systems, and illustrates current and potential applications of light-driven systems.

Transport Phenomena in Microfluidic Systems

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118298411
Total Pages : 554 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Transport Phenomena in Microfluidic Systems by : Pradipta Kumar Panigrahi

Download or read book Transport Phenomena in Microfluidic Systems written by Pradipta Kumar Panigrahi and published by John Wiley & Sons. This book was released on 2016-02-15 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully comprehensive introduction to the rapidly emerging area of micro systems technology Transport Phenomena in Micro Systems explores the fundamentals of the new technologies related to Micro-Electro-Mechanical Systems (MEMS). It deals with the behavior, precise control and manipulation of fluids that are geometrically constrained to a small, typically sub-millimeter, scale, such as nl, pl, fl, small size, low energy consumption, effects of the micro domain and heat transfer in the related devices. The author describes in detail and with extensive illustration micro fabrication, channel flow, transport laws, magnetophoresis, micro scale convection and micro sensors and activators, among others. This book spans multidisciplinary fields such as material science and mechanical engineering, engineering, physics, chemistry, microtechnology and biotechnology. Brings together in one collection recent and emerging developments in this fast-growing area of micro systems Covers multidisciplinary fields such as materials science, mechanical engineering, microtechnology and biotechnology, et al Comprehensive coverage of analytical models in microfluidics and MEMS technology Introduces micro fluidics applications include the development of inkjet printheads, micro-propulsion, and micro thermal technologies Presented in a very logical format Supplies readers with problems and solutions