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Author : J.H. Kägi
Publisher : Birkhäuser
ISBN 13 : 3034867840
Total Pages : 723 pages
Book Rating : 4.0/5 (348 download)
Download or read book Metallothionein II written by J.H. Kägi and published by Birkhäuser. This book was released on 2014-03-27 with total page 723 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paolo Zatta
Publisher : World Scientific
ISBN 13 : 9812778934
Total Pages : 335 pages
Book Rating : 4.8/5 (127 download)
Download or read book Metallothioneins in Biochemistry and Pathology written by Paolo Zatta and published by World Scientific. This book was released on 2008 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metallothioneins (MTs) represent a large family of proteins characterized by high heavy metal content (mainly CuII and ZnII) and by an unusual cysteine abundance. They have a powerful protective function in all animal tissues, due most likely to their properties as free radical scavengers protecting against oxidative damage. Moreover, the presence and overexpression of MTs in various pathological conditions, such as metal dyshomeostasis, cell proliferation, neurological disorders, and chemotherapy and radiotherapy resistance, could be used as an important prognostic marker, as a histopathological diagnostic tool, and to follow specific pharmacological treatments.This important book explores the role of MTs in the field of neurological disorders (brain inflammation, Alzheimer's and prion diseases, autism, ALS, etc.), cardiology (cardiomyopathy, atherosclerosis), and oncology (melanoma, prostate and breast cancer), through authoritative contributions and a description of basic biochemical information and paradigmatic pathological events.
Author : Astrid Sigel
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 311043301X
Total Pages : 633 pages
Book Rating : 4.1/5 (14 download)
Download or read book Lead: Its Effects on Environment and Health written by Astrid Sigel and published by Walter de Gruyter GmbH & Co KG. This book was released on 2017-04-10 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 17, entitled Lead: Its Effects on Environment and Health of the series Metal Ions in Life Sciences centers on the interrelations between biosystems and lead. The book provides an up-to-date review of the bioinorganic chemistry of this metal and its ions; it covers the biogeochemistry of lead, its use (not only as gasoline additive) and anthropogenic release into the environment, its cycling and speciation in the atmosphere, in waters, soils, and sediments, and also in mammalian organs. The analytical tools to determine and to quantify this toxic element in blood, saliva, urine, hair, etc. are described. The properties of lead(II) complexes formed with amino acids, peptides, proteins (including metallothioneins), nucleobases, nucleotides, nucleic acids, and other ligands of biological relevance are summarized for the solid state and for aqueous solutions as well. All this is important for obtaining a coherent picture on the properties of lead, its effects on plants and toxic actions on mammalian organs. This and more is treated in an authoritative and timely manner in the 16 stimulating chapters of Volume 17, which are written by 36 internationally recognized experts from 13 nations. The impact of this recently again vibrant research area is manifested in nearly 2000 references, over 50 tables and more than 100 illustrations (half in color). Lead: Its Effects on Environment and Health is an essential resource for scientists working in the wide range from material sciences, inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching.
Author : J.H. Kägi
Publisher : Birkhäuser
ISBN 13 : 9783764318048
Total Pages : 755 pages
Book Rating : 4.3/5 (18 download)
Download or read book Metallothionein II written by J.H. Kägi and published by Birkhäuser. This book was released on 1987-01-01 with total page 755 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Curtis D. Klaassen
Publisher : CRC Press
ISBN 13 : 9780849388323
Total Pages : 436 pages
Book Rating : 4.3/5 (883 download)
Download or read book Metallothionein in Biology and Medicine written by Curtis D. Klaassen and published by CRC Press. This book was released on 1991-08-27 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together work from leading researchers to present the most recent advances in research on metallothionein. This protein interests toxicologists because it is thought that metallothionein protects against metal toxicity and possibly against oxidative stress. It is of interest to pharmacologists because modification of metallothionein levels might have a role in cancer chemotherapy. Nutritionists have an interest in this protein because it appears to be a major storage protein for zinc. Biochemists and molecular biologists will be interested in the mechanisms of regulation of this protein because it is extremely inducible.
Author : C. Klaasen
Publisher : Birkhäuser
ISBN 13 : 3034888473
Total Pages : 641 pages
Book Rating : 4.0/5 (348 download)
Download or read book Metallothionein IV written by C. Klaasen and published by Birkhäuser. This book was released on 2012-12-06 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Proceedings of the Fourth International Metallothionein Meeting (MT-97) feature the latest research on metallothionein. The book covers a broad range of topics which provide important information for both basic and clinical investigators. The selected 94 articles in this book are written by the leading scientists in the field around the world. This is an increasingly important, multi-disciplinary area of study that has benefitted from recent advances in concepts and methodologies from other fields.
Author : Jeremias H. R. Kägi
Publisher : Birkhauser
ISBN 13 :
Total Pages : 776 pages
Book Rating : 4.3/5 (91 download)
Download or read book Metallothionein II written by Jeremias H. R. Kägi and published by Birkhauser. This book was released on 1987 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kazuo T. Suzuki
Publisher : Birkhauser
ISBN 13 :
Total Pages : 504 pages
Book Rating : 4.:/5 (318 download)
Download or read book Metallothionein III written by Kazuo T. Suzuki and published by Birkhauser. This book was released on 1993 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Parvaiz Ahmad
Publisher : Elsevier
ISBN 13 : 0128031832
Total Pages : 652 pages
Book Rating : 4.1/5 (28 download)
Download or read book Plant Metal Interaction written by Parvaiz Ahmad and published by Elsevier. This book was released on 2016-02-02 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Metal Interaction: Emerging Remediation Techniques covers different heavy metals and their effect on soils and plants, along with the remediation techniques currently available. As cultivable land is declining day-by-day as a result of increased metals in our soil and water, there is an urgent need to remediate these effects. This multi-contributed book is divided into four sections covering the whole of plant metal interactions, including heavy metals, approaches to alleviate heavy metal stress, microbial approaches to remove heavy metals, and phytoremediation. Provides an overview of the effect of different heavy metals on growth, biochemical reactions, and physiology of various plants Serves as a reference guide for available techniques, challenges, and possible solutions in heavy metal remediation Covers sustainable technologies in uptake and removal of heavy metals
Author : Piotr Dziegiel
Publisher : Springer
ISBN 13 : 3319274724
Total Pages : 117 pages
Book Rating : 4.3/5 (192 download)
Download or read book Metallothioneins in Normal and Cancer Cells written by Piotr Dziegiel and published by Springer. This book was released on 2016-02-04 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the structures of Metallothionein (MT) family members and the cellular functions of MT-1, MT-2 and MT-4 isoforms, as well as provides insights into divergent biological roles of MT-3. The authors explain the involvement of MT molecules in various processes related to carcinogenesis, including an organ-specific presentation of current data concerning their potential impact on the progression of various tumors and the regulatory role of MT family members in the function of the immune system.
Author : W. Maret
Publisher : Springer Science & Business Media
ISBN 13 : 9401737282
Total Pages : 232 pages
Book Rating : 4.4/5 (17 download)
Download or read book Zinc Biochemistry, Physiology, and Homeostasis written by W. Maret and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapters in this book review the remarkable advances in the field of zinc biology over the last decade. Zinc is essential for life, in particular for growth and development, through its role in hundreds of zinc enzymes and thousands of zinc proteins. Its catalytic, structural, and regulatory functions in these proteins impact metabolism, gene expression, and signal transduction, including neurotransmission. Among the micronutrients, zinc may rank with iron as to its importance for public health. The topics covered range from single molecules to cells and to whole organisms: the chemistry, design, and application of fluorophores for the determination of cellular zinc; the role of zinc in proliferation, differentiation, and apoptosis of cells; proteins that transport, sense, and distribute zinc and together form a cellular homeostatic system; the coordination chemistry of zinc in metalloproteins; the role of zinc in the brain as a neuromodulator/transmitter; the dependence of the immune system on zinc; zinc homeostasis in the whole human body.
Author :
Publisher :
ISBN 13 : 9814472379
Total Pages : pages
Book Rating : 4.8/5 (144 download)
Download or read book Metallothioneins in Biochemistry and Pathology written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Astrid Sigel
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110436272
Total Pages : 544 pages
Book Rating : 4.1/5 (14 download)
Download or read book Metallothioneins and Related Chelators written by Astrid Sigel and published by Walter de Gruyter GmbH & Co KG. This book was released on 2015-07-24 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: These sulfur-rich chelators, being important in metal ion homeostasis, find increasing attention. MILS-5, written by 30 internationally recognized experts, focuses on this hot topic. The reader is supported by about 20 tables, more than 80 illustrations and nearly 2000 references. This book is an essential resource for scientists working in a wide range of disciplines from environmental toxicology and inorganic biochemistry all the way through to physiology and medicine.
Author : Herbert B. Newton
Publisher : Elsevier
ISBN 13 : 9780080455938
Total Pages : 586 pages
Book Rating : 4.4/5 (559 download)
Download or read book Handbook of Brain Tumor Chemotherapy written by Herbert B. Newton and published by Elsevier. This book was released on 2005-12-19 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatment of patients with a brain tumor remains one of the most challenging and difficult areas of modern oncology. Recent advances in the molecular biology of these neoplasms have improved our understanding of the malignant phenotype and have lead to the development of novel forms of chemotherapy, including “targeted agents. The Handbook of Brain Tumor Chemotherapy reviews the state-of-the-art of chemotherapy development and clinical treatment of patients with this devastating disease. Handbook of Brain Tumor Chemotherapy offers a unique cutting-edge compendium of basic science and clinical information on the subject of brain tumor chemotherapy, reviewing what has been accomplished thus far and how the field will continue to evolve with the development of more specific and efficacious chemotherapeutic agents. This book represents the most complete single-volume resource available for information on the subject of brain tumor chemotherapy. Provides the most up to date information regarding conventional forms of cytotoxic chemotherapy, as well as the basic science and clinical application of molecular therapeutics, for the treatment of brain tumors Broadly appeals to anyone interested in the field of Neuro-Oncology and in the treatment of patients with brain tumors Useful to clinicians interested in a thorough overview of the use of chemotherapy in patients with a broad range of brain tumors as well as serving as a source of background information to basic scientists and pharmaceutical researchers with an interest in the molecular therapeutics of brain tumors
Author :
Publisher :
ISBN 13 :
Total Pages : 962 pages
Book Rating : 4.F/5 ( download)
Download or read book Environmental Health Perspectives written by and published by . This book was released on with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 1328 pages
Book Rating : 4.3/5 (243 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1988 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rudolfs K. Zalups
Publisher : CRC Press
ISBN 13 : 9780748407989
Total Pages : 608 pages
Book Rating : 4.4/5 (79 download)
Download or read book Molecular Biology and Toxicology of Metals written by Rudolfs K. Zalups and published by CRC Press. This book was released on 2000-02-24 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology and Toxicology of Metals provides a critical review and analysis of the current state of knowledge of metal ion transport and metabolism in prokaryotic and eukaryotic cellular systems. It covers the latest information on specific metals and the biological molecules with which metals interact. It also details mechanisms in the handling and toxicity of metals in specific organ systems, and the role of metals in cell signalling and gene transcription in target cells. This book is sure to prove a fertile meeting ground for the disciplines of molecular genetics and metal toxicology.
