GI Epidemiology

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Publisher : John Wiley & Sons
ISBN 13 : 047069145X
Total Pages : 289 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis GI Epidemiology by : Nicholas J. Talley

Download or read book GI Epidemiology written by Nicholas J. Talley and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authoritative new text from the experts in GI populationstudies This book covers both key methodological issues and the mostimportant information in the field, disease by disease. It focuseson population-based information and studies looking at principlesand approaches to diagnosis and treatment of diseases. GI Epidemiology brings together world authorities inmultiple disciplines for the very first time, to create one clearand comprehensive source. The bulk of the chapters are divided intotwo parts, covering methodological issues and the epidemiology ofspecific GI diseases. Each chapter begins with a list of keypoints, followed by a review written in a clear and simplestyle. The methodologic chapters cover evidence-based medicine,meta-analysis, systematic reviews, genetic and molecularepidemiology, clinical trials, questionnaire design, and healtheconomics. The disease-specific chapters note the current gaps inknowledge and suggest areas for further study. GI Epidemiology serves as both a useful refresher and areliable reference on the methods and techniques used inepidemiological studies for consultants and researchers ingastroenterology. It is also an invaluable tool for fellows/trainees ingastroenterology, candidates for recertification in the combineddisciplines of gastroenterology, pediatric gastroenterology andcolorectal surgery, and anyone completing MPH training.

Metabolic Steatotic Liver Disease

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Author :
Publisher : Elsevier
ISBN 13 : 0323996507
Total Pages : 340 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Metabolic Steatotic Liver Disease by : Mindie Nguyen

Download or read book Metabolic Steatotic Liver Disease written by Mindie Nguyen and published by Elsevier. This book was released on 2024-06-26 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Fatty Liver Disease: Current Knowledge, Therapeutic Treatments, and Future Directions provides the most updated research findings and defines the current data gaps on metabolic fatty liver disease. The book extensively covers key areas in metabolic fatty liver disease research, including epidemiology (adults and children), economic burden, patient-reported outcome burden, natural history, current treatments, current diagnostic methods, controversies (NAFLD/MAFLD), current guidelines, fatty liver disease in the presence of other liver diseases as well as guidance on future research. This book will provide translational researchers with a current and comprehensive resource dedicated to all aspects of research in metabolic fatty liver disease, identify current gaps in research and make future research recommendations. It also offers clinicians a look at important background information in metabolic fatty liver disease and thoroughly reviews the latest research in this area to inform treatment outcomes. Compiles the latest, up-to-date science from key experts in the field on metabolic fatty liver disease Reviews best practices and current guidelines for a comprehensive overview Identifies recommendations for future research endeavors

Fatty Liver Disease

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 140514100X
Total Pages : 336 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Fatty Liver Disease by : Geoffrey C. Farrell

Download or read book Fatty Liver Disease written by Geoffrey C. Farrell and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fatty Liver Diseases: NASH and Related Disorders is an unusual book: it combines a practical approach for students and physicians concerned with the problem with a clear overview on the causative mechanisms. It appeals to doctors and other health care workers who encounter this problem, as well as to pathologists and investigators interested in the field of liver disease. It will improve your diagnostic acumen for people with abnormal liver tests, advance your knowledge about this important subject and help with your specialist or undergraduate exams, and management of a common disorder.

Metabolic Aspects of Chronic Liver Disease

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Publisher : Nova Publishers
ISBN 13 : 9781600212017
Total Pages : 392 pages
Book Rating : 4.2/5 (12 download)

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Book Synopsis Metabolic Aspects of Chronic Liver Disease by : Ami Schattner

Download or read book Metabolic Aspects of Chronic Liver Disease written by Ami Schattner and published by Nova Publishers. This book was released on 2008 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses in detail new aspects of the metabolic basis of important chronic liver diseases. Entities such as non-alcoholic fatty liver disease (fatty liver and Non-Alcoholic SteatoHepatitis -- NASH), diabeties in chronic hepetitis C, hemochromatosis, Wilson's disease, Gaucher disease, porphyria, as well as liver cirrhosis and its metabolic consequences will be discussed in detail. These clinical conditions are highly prevalent and affect millions of patients in the USA and world-wide. For example, non-alcoholic fatty liver disease is the most common cause of elevated liver enzymes in the general population. This field has been practically transformed over the last few years, with many new insights gained, regarding both pathogenesis and effective novel treatments.

Liver Metabolism and Fatty Liver Disease

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Author :
Publisher : CRC Press
ISBN 13 : 1482212455
Total Pages : 344 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Liver Metabolism and Fatty Liver Disease by : Oren Tirosh

Download or read book Liver Metabolism and Fatty Liver Disease written by Oren Tirosh and published by CRC Press. This book was released on 2014-08-27 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonalcoholic fatty liver disease is one of the most common liver diseases worldwide affecting patients from all ages, races, and ethnic backgrounds. It comprises a spectrum of hepatic pathology ranging from simple steatosis, in which there is an increase of fat accumulation in hepatocytes, to nonalcoholic steatohepatitis and cirrhosis. The significant prevalence of this disease—between 15 and 45 percent of the general population—means that it contributes to an increased burden of ill health both today and in the future. Liver Metabolism and Fatty Liver Disease addresses the current understanding of the development of nonalcoholic fatty liver disease as well as the clinical aspects of the disease by examining the current knowledge surrounding metabolism in the liver. The book discusses various topics including the involvement of oxidative stress, metabolic effects, and inflammation as well as the effect of nutrition on the development and progression of the disease.

Breaking the Crisis on Non-Alcoholic Fatty Liver Disease

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Author :
Publisher : Independently Published
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.8/5 (834 download)

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Book Synopsis Breaking the Crisis on Non-Alcoholic Fatty Liver Disease by : Dr Rundell Meehan

Download or read book Breaking the Crisis on Non-Alcoholic Fatty Liver Disease written by Dr Rundell Meehan and published by Independently Published. This book was released on 2024-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Are you tired of feeling helpless in the face of Non-Alcoholic Fatty Liver Disease (NAFLD)? Do you want to take charge of your liver health and break free from the crisis it brings? Look no further! "Breaking the Crisis on Non-Alcoholic Fatty Liver Disease" is your ultimate guide to understanding, managing, and conquering NAFLD. In this groundbreaking book, you'll embark on a journey through the intricate landscape of NAFLD, starting with a deep dive into its origins, prevalence, and global impact. From unraveling the mystery of NAFLD to exploring its various stages, complications, and comorbidities, every chapter is a revelation. Delve into the anatomy of the liver and grasp its pivotal role in NAFLD development. Learn about the spectrum of NAFLD, from simple steatosis to the advanced stages fraught with complications like hepatocellular carcinoma and heart problems. But fear not, as this book arms you with the knowledge and techniques needed to intervene and supervise your liver health effectively. Discover the myriad risk factors and contributors to NAFLD, from genetics to metabolic syndrome, insulin resistance, and diabetes. Equip yourself with the tools for diagnosis and screening, including clinical evaluation, imaging techniques, and laboratory tests, ensuring early detection and proactive management. But knowledge alone is not enough; actionable steps are crucial. Learn how lifestyle modifications, dietary strategies, physical activity, and weight management can significantly impact NAFLD progression. Explore pharmacological interventions and emerging therapies, alongside the challenges and future developments in treatment options. As you journey through the pages, gain invaluable insights into the comorbidities associated with NAFLD, understanding its cardiovascular implications, type 2 diabetes connection, and impact on overall health. Walk alongside patients as they share their perspectives, coping strategies, and support networks, offering invaluable wisdom and solidarity. Moreover, "Breaking the Crisis on Non-Alcoholic Fatty Liver Disease" doesn't stop at individual health; it extends to prevention and public health initiatives. Dive into discussions on public awareness, education, policy implications, and future directions in NAFLD prevention, advocating for systemic change and collective action. This book is not just a passive read; it's a call to action-a roadmap to reclaiming your liver health and transforming your life. Don't let NAFLD dictate your future; empower yourself with knowledge, strategies, and a commitment to wellness. Your liver deserves nothing less. Take the first step towards a healthier tomorrow-GRAB YOUR COPY of "Breaking the Crisis on Non-Alcoholic Fatty Liver Disease" now and embark on a journey of healing, resilience, and triumph.

Nonalcoholic Fatty Liver Disease (NAFLD)

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 1681084651
Total Pages : 188 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Nonalcoholic Fatty Liver Disease (NAFLD) by : Tatjana Ábel

Download or read book Nonalcoholic Fatty Liver Disease (NAFLD) written by Tatjana Ábel and published by Bentham Science Publishers. This book was released on 2017-05-05 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-alcoholic fatty liver disease (NAFLD) is a common cause of elevated liver enzymes and chronic liver disease in Western countries. NAFLD is characterized by elevated liver enzymes in the absence of alcohol consumption and secondary causes of liver disease. It is an independent predictor of future risk of cardiovascular diseases, type 2 diabetes and metabolic syndrome (hypertension, abdominal obesity, dyslipidemia, glucose intolerance). This book is a quick reference guide for medical students and professionals about NAFLD. Readers will find a summary of epidemiology, clinical features, diagnosis, imaging techniques, histopathology, and disease management. The book also presents information about NAFLD linked with hepatocellular carcinoma and guidelines for treating NAFLD in pediatric patients. Each chapter presents information in a simple, structured manner making this text an ideal handbook for supplementing hepatology modules in medical curricula.

Non-Alcoholic Fatty Liver Disease

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535139231
Total Pages : 192 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Non-Alcoholic Fatty Liver Disease by : Rodrigo Valenzuela Baez

Download or read book Non-Alcoholic Fatty Liver Disease written by Rodrigo Valenzuela Baez and published by BoD – Books on Demand. This book was released on 2018-03-21 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonalcoholic fatty liver disease (NAFLD) with a prevalence of 20-30% worldwide is characterized by the buildup of fat in the liver (liver steatosis) with no or little alcohol consumption. Its principal causes are modern diet and occidental lifestyle. It is characterized by metabolic disturbances such as insulin resistance, inflammation, and oxidative stress, considered as the hepatic manifestation of metabolic syndrome. There is no effective drug therapy for this disease; therefore, lifestyle interventions remain as the first-line treatment. Nevertheless, the adherence rates to this type of treatment are very low, so great efforts are focused at finding novel therapeutic agents for the prevention of hepatic steatosis and its progression. This book presents a systematic and comprehensive revision about NAFLD, highlighting its epidemiological and molecular aspects, as well as its prevention and treatment.

Translational Research Methods in Diabetes, Obesity, and Nonalcoholic Fatty Liver Disease

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Author :
Publisher : Springer
ISBN 13 : 3030117480
Total Pages : 556 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Translational Research Methods in Diabetes, Obesity, and Nonalcoholic Fatty Liver Disease by : Andrew J. Krentz

Download or read book Translational Research Methods in Diabetes, Obesity, and Nonalcoholic Fatty Liver Disease written by Andrew J. Krentz and published by Springer. This book was released on 2019-04-02 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to aid the selection of the most appropriate methods for use in early phase (1 and 2) clinical studies of new drugs for diabetes, obesity, non-alcoholic fatty liver disease (NAFLD) and related cardiometabolic disorders. Clinical research methods to assess the pharmacokinetics and pharmacodynamics of new diabetes drugs, e.g. the euglycemic clamp technique, have become well-established in proof-of-mechanism studies. However, selection of the most appropriate techniques is by no means straightforward. Moreover, the application of such methods must conform to the regulatory requirements for new drugs. This book discusses the need for new pharmacotherapies for diabetes, obesity and NAFLD and the molecular targets of drugs currently in development. Emerging technologies including functional imaging, circulating biomarkers and omics are considered together with practical and ethical issues pertaining to early phase clinical trials in subjects with cardiometabolic disorders. Translational Research Methods in Diabetes, Obesity, and Non-Alcoholic Fatty Liver Disease is of interest to biomedical scientists, pharmacologists, academics involved in metabolic research and clinicians practicing in these specialties.

Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118912039
Total Pages : 273 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease by : Roger Williams

Download or read book Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease written by Roger Williams and published by John Wiley & Sons. This book was released on 2016-05-02 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease offers hepatologists practical, up-to-date and expert guidance on the most topical dilemmas, difficulties and areas of controversy/difficulty surrounding this ever-increasing area of liver disease they face in daily practice. Roger Williams and Simon Taylor-Robinson, two of Europe’s leading hepatologists, have recruited leading figures from across the world to assist them, resulting in a truly international approach. Each chapter covers a specific area of difficulty, containing clear learning points and providing evidence-based expert guidance on the latest hot topics in clinical management such as: Is NAFLD different in absence of Metabolic Syndrome? Are the pros outweighed by the cons of obtaining a liver biopsy? Is progression to cirrhosis more likely in children with NAFLD? What are the dangers as well as the true benefits of bariatric surgery? How is it best to use antifibrotic agents in clinical practice? Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease provides the answers to the questions and challenges that clinicians face every day in this area. It is essential reading for hepatologists of all levels and researchers in hepatology, as well as all those involved in the care of patients with NAFLD, including gastroenterologists, pathologists and specialist hepatology nurses.

Need-to-Know NAFLD

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Author :
Publisher : CRC Press
ISBN 13 : 1000928667
Total Pages : 556 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Need-to-Know NAFLD by : Naim Alkhouri

Download or read book Need-to-Know NAFLD written by Naim Alkhouri and published by CRC Press. This book was released on 2023-09-08 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the obesity and metabolic syndrome epidemics, which this up-to-date book deals with comprehensively. The contents outline disease mechanisms, diagnostic tests, management, varying manifestations, and special populations. It covers the mechanistic pathways that contribute to NAFLD development, including the role of genetic variants and the gut microbiome. It elaborates on noninvasive diagnostic tests to screen for NAFLD, determine its severity, and monitor response to lifestyle intervention and pharmacologic treatment. This book helps clinicians diagnose and treat this common and potentially deadly disease. Key Features: Reviews current drugs in development and provides practical advice to clinicians on the diagnosis and management of fatty liver. Proves attractive to primary care providers who are on the front line of managing patients with NAFLD, to gastroenterologists and hepatologists who would benefit from updated data on how to risk-stratify patients and identify those who will be eligible for pharmacologic treatment, and other specialists such as cardiologists, endocrinologists, and nephrologists who will find this book to be a useful reference on the extrahepatic manifestations of NAFLD. Focuses on extrahepatic manifestations and new insights on the mechanistic drivers of the disease.

The Liver

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Publisher : John Wiley & Sons
ISBN 13 : 1119436826
Total Pages : 1156 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis The Liver by : Irwin M. Arias

Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Insulin Resistance and Nonalcoholic Fatty Liver Disease (NAFLD)/nonalcoholic Steatohepatitis (NASH)

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Author :
Publisher : Nova Science Publishers
ISBN 13 : 9781616689278
Total Pages : 0 pages
Book Rating : 4.6/5 (892 download)

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Book Synopsis Insulin Resistance and Nonalcoholic Fatty Liver Disease (NAFLD)/nonalcoholic Steatohepatitis (NASH) by : Masato Yoneda

Download or read book Insulin Resistance and Nonalcoholic Fatty Liver Disease (NAFLD)/nonalcoholic Steatohepatitis (NASH) written by Masato Yoneda and published by Nova Science Publishers. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The liver is the first organ to receive nutrients that enter the body via the intestines after a meal, and this organ plays a pivotal role in energy metabolism. Non-alcoholic fatty liver disease (NAFLD) is among the most common causes of chronic liver disease in the world and is now considered to be a component of metabolic syndrome. A wide spectrum of histological changes has been observed in NAFLD, ranging from simple steatosis, which is generally non-progressive, to nonalcoholic steatohepatitis (NASH), liver cirrhosis, liver failure, and sometimes even hepatocellular carcinoma. This book reviews recent evidence concerning insulin resistance and NAFLD/NASH as a step towards a comprehensive understanding of the pathophysiology and treatment of NAFLD/NASH.

The Metabolic Syndrome

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Publisher : John Wiley & Sons
ISBN 13 : 1444336584
Total Pages : 384 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis The Metabolic Syndrome by : Christopher D. Byrne

Download or read book The Metabolic Syndrome written by Christopher D. Byrne and published by John Wiley & Sons. This book was released on 2011-08-22 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Metabolic Syndrome is a valuable reference text, covering all aspects of the metabolic syndrome and its constituent diseases including inflammation, oxidation and adipocytokines. This book explains the aetiology, pathogenesis and clinical treatment of all risk factors as well as the relationship with diabetes, non alcoholic fatty liver disease, polycystic ovary syndrome and coronary heart disease. The Metabolic Syndrome has been further improved from the 1st edition that was highly commended in 2006 Annual British Medical Association medical books competition. All chapters from the first edition are fully updated and this new edition contains an increase in international contributions and five new chapters on: Childhood obesity and metabolic syndrome Bariatric surgery for obesity Fitness Brain insulin resistance and appetite The nature of the insulin resistance seen in metabolic syndrome. This brand new edition of The Metabolic Syndrome will be an indispensable resource for all clinical researchers, physicians and scientists requiring detailed up-to-date information on the metabolic syndrome to further their own research or to treat and manage the syndrome and its complications. Specifically, the text will be of particular relevance to those involved and working in the fields of diabetes, endocrinology, obesity, cardiology, vascular disease and hepatology.

Variceal Hemorrhage

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1493900021
Total Pages : 266 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Variceal Hemorrhage by : Roberto de Franchis

Download or read book Variceal Hemorrhage written by Roberto de Franchis and published by Springer Science & Business Media. This book was released on 2014-01-25 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Variceal Hemorrhage provides an update of the evidence concerning several aspects of variceal hemorrhage. The book features new information on natural history, diagnosis of esophageal varices, assessment of the risk of bleeding and identification of high risk groups and patients who may benefit or be harmed from different treatments. The volume also presents a critical analysis of the different steps in the management of acute variceal bleeding. Authored by the most prominent world experts in their areas of expertise, Variceal Hemorrhage serves as a very useful reference for gastroenterologists, GI surgeons, residents in internal medicine and physicians dealing with and interested in the different aspects of this severe medical emergency.

Non-Alcoholic Fatty Liver Disease

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118556224
Total Pages : 438 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Non-Alcoholic Fatty Liver Disease by : Geoffrey C. Farrell

Download or read book Non-Alcoholic Fatty Liver Disease written by Geoffrey C. Farrell and published by John Wiley & Sons. This book was released on 2013-02-06 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sharp rise in cases of Non-alcoholic fatty liver disease is fast becoming one of the major concerns for hepatologists worldwide. This comprehensive clinical guide explains how to diagnose NAFLD and manage patients according to the best standards of care. Contributors from the world's leading institutions concentrate on patient care, drawing on their extensive experience.

Metabolic-associated fatty liver disease, An Issue of Endocrinology and Metabolism Clinics of North America, E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0443184089
Total Pages : 177 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Metabolic-associated fatty liver disease, An Issue of Endocrinology and Metabolism Clinics of North America, E-Book by : Joseph M. Pappachan

Download or read book Metabolic-associated fatty liver disease, An Issue of Endocrinology and Metabolism Clinics of North America, E-Book written by Joseph M. Pappachan and published by Elsevier Health Sciences. This book was released on 2023-07-25 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Sherouk Fouda and Joseph M. Pappachan bring their considerable expertise to the topic of Metabolic Associated Fatty Liver Disease. Top experts address the various ways metabolic associated fatty liver disease is related to other conditions such as diabetes, sarcopenia, PCOS, and more, as well as the management of MAFLD and cardiovascular implications. Contains 12 practice-oriented topics including obstructive sleep apnea and MAFLD; the interlink between MAFLD and polycystic ovary syndrome; pregnancy and MAFLD; MAFLD and gut microbiota; and more. Provides in-depth clinical reviews of metabolic associated fatty liver disease, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.