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Author : Dennis Dollens
Publisher :
ISBN 13 : 9780692955222
Total Pages : 185 pages
Book Rating : 4.9/5 (552 download)
Download or read book Metabolic Architectures written by Dennis Dollens and published by . This book was released on 2016 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Dennis Dollens
Publisher :
ISBN 13 : 9781549954474
Total Pages : 184 pages
Book Rating : 4.9/5 (544 download)
Download or read book Metabolic Architectures written by Dennis Dollens and published by . This book was released on 2017-10-13 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Metabolic Architectures: Turing, Sullivan, Autopoiesis & AI, Dennis Dollens writes a manifesto for dialectically bracketing AI with plant and microbial intelligence when we consider them scientifically, phenomenally, and environmentally. Dollens further argues that architecture is as much a part of nature as spider webs, beehives, and cricket burrows, thereby establishing buildings as biologically derived, extended phenotypes. Proposing a theoretical Extended Autopoietic Operating System (EA/OS) by means of computational simulations, hybridization, and genetics, he situates autonomous and microbially-intelligent buildings as metabolic within a machinic phylum. On this basis, Metabolic Architectures challenges us to develop non-human, sentient roles for buildings and cities where bio and AI intelligences serve as sentinels, organizers, and actuator-organisms to mediate climate change. Dollens develops his analysis from close observations of Alan Turing's morphogenetic drawings and papers as they relate to algorithmic programming and machine intelligence. From Louis Sullivan's A System -- unfolded as a precursor and analog corollary of Turing's work -- he extracts ways of hybridizing botanic life with geometric forms. Following Richard Dawkins, he concludes that metabolic architectures are extensions of human biology and thus biomachinic parts of nature. And by reformulating Turing's question, "Can machines think?" as Can buildings think? -- his book seeds a debate on the ways that architects may visualize biointelligent, performative buildings -- buildings as sensory agents in the environment. Metabolic Architectures strategically expands biological theory from Maturana and Varela's Autopoiesis and Cognition with adaptive modifications from contemporary philosophers and scientists. In this strategy, Andy Clark's research on extended cognition, underpins the hybridization of theory and practice to construct scaffolding for design, tool making, and architecture as inseparable from urban and wild nature. In his introduction, Alberto T. Est�vez references university biodigital and genetic-architectures investigated and prototyped in ESARQ's Biodigital Architecture Master and Ph.D. Program, a program Est�vez founded and directs and where Dollens teaches. In that context, Dollens illustrates and explains steps by which architecture may evolve toward biological life by hybridizing microbial and/or plant intelligence in a process impacting and impacted by AI, ALife, and synthetic biology. Metabolic Architectures posits bioarchitecture as big machines inthe midst of other machines, such as computers, smartphones, and neural-net programming to guide experimental research and studio practices toward the integration of algorithmic morphology from nature. Once understood as gigantic machines -- intelligent, sensory architectures stake a position in debate where monitoring and recognition of toxins and their bioremediation emerge as immediate concerns. Metabolic Architectures, thereafter positions cognition and nature in the setting of bioreactive architecture design, partnering architects with microbial intelligence, AI, and technology to conceptualize sentient buildings as remedial agents addressing, for example, climate change through sensory and biochemical, carbon-eating bacteria.
Author : Soumen Chakraborty
Publisher : Frontiers Media SA
ISBN 13 : 2832514847
Total Pages : 221 pages
Book Rating : 4.8/5 (325 download)
Download or read book Reprogramming the Cellular, Molecular and Metabolic Architecture of the Tumor Microenvironment for Effective Cancer Immunotherapy written by Soumen Chakraborty and published by Frontiers Media SA. This book was released on 2023-02-16 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kishō Kurokawa
Publisher :
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.:/5 (321 download)
Download or read book Metabolism in Architecture written by Kishō Kurokawa and published by . This book was released on 1977 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even in a country where outstanding achievements have become almost a commonplace, the Japanese architect, Kisho Kurokawa, appears as both a remarkable and a remarkably successful man. With buildings in the United States and Eastern and Western Europe as well as in Japan, he has established an international reputation as a leading figure amongst the younger generation of architects. At the age of forty he already had thirty-five major buildings and seventeen books to his credit; four new towns are being built to his designs; he heads a company of over a hundred employees, he runs a think-tank and an urban design bureau and for variety he has his own television programme with a regular audience of some 30 million. Behind these statistics lies a prodigious vitality expressed in original and stimulating buildings. -- from book jacket.
Author : Christina Smolke
Publisher : CRC Press
ISBN 13 : 1420005626
Total Pages : 1247 pages
Book Rating : 4.4/5 (2 download)
Download or read book The Metabolic Pathway Engineering Handbook, Two Volume Set written by Christina Smolke and published by CRC Press. This book was released on 2009-08-18 with total page 1247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Christina Smolke, who recently developed a novel way to churn out large quantities of drugs from genetically modified brewer's yeast, is regarded as one of the most brilliant minds in biomedical engineering. In this handbook, she brings together pioneering scientists from dozens of disciplines to provide a complete record of accomplishment in metab
Author : Christina Smolke
Publisher : CRC Press
ISBN 13 : 142007766X
Total Pages : 570 pages
Book Rating : 4.4/5 (2 download)
Download or read book The Metabolic Pathway Engineering Handbook written by Christina Smolke and published by CRC Press. This book was released on 2009-07-28 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second volume of the Metabolic Pathway Engineering Handbook delves into evolutionary tools and gene expression tools for metabolic pathway engineering. It covers applications of emerging technologies including recent research genome-wide technologies, DNA and phenotypic microarrays, and proteomics tools for experimentally determining flux thro
Author : Oriol Güell
Publisher : Springer
ISBN 13 : 3319640003
Total Pages : 162 pages
Book Rating : 4.3/5 (196 download)
Download or read book A Network-Based Approach to Cell Metabolism written by Oriol Güell and published by Springer. This book was released on 2017-08-16 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis uses a systems-level approach to study the cellular metabolism, unveiling new mechanisms and responses that were impossible to reach with traditional reductionists procedures. The results reported here have a potential application in areas like metabolic engineering and disease treatment. They could also be used in determining the accuracy of the gene essentiality of new genome-scale reconstructions. Different methods and techniques, within the contexts of Systems Biology and the field known as Complex Networks Analysis have been applied in this work to show different features of the robustness of metabolic networks. The specific issues addressed here range from pure topological aspec ts of the networks themselves to the balance of biochemical fluxes.
Author : Peter Baccini
Publisher : MIT Press
ISBN 13 : 0262016656
Total Pages : 405 pages
Book Rating : 4.2/5 (62 download)
Download or read book Metabolism of the Anthroposphere, second edition written by Peter Baccini and published by MIT Press. This book was released on 2012-02-10 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the cultural evolution of material flows and stocks with an emphasis on the design of metabolic processes in urban systems. Over the last several thousand years of human life on Earth, agricultural settlements became urban cores, and these regional settlements became tightly connected through infrastructures transporting people, materials, and information. This global network of urban systems, including ecosystems, is the anthroposphere; the physical flows and stocks of matter and energy within it form its metabolism. This book offers an overview of the metabolism of the anthroposphere, with an emphasis on the design of metabolic systems. It takes a cultural historical perspective, supported with methodology from the natural sciences and engineering. The book will be of interest to scholars and practitioners in the fields of regional development, environmental protection, and material management. It will also be a resource for undergraduate and graduate students in industrial ecology, environmental engineering, and resource management. The authors describe the characteristics of material stocks and flows of human settlements in space and time; introduce the method of material flow analysis (MFA) for metabolic studies; analyze regional metabolism and the material systems generated by basic activities; and offer four case studies of optimal metabolic system design: phosphorus management, urban mining, waste management, and mobility. This second edition of an extremely influential book has been substantially revised and greatly expanded. Its new emphasis on design and resource utilization reflects recent debates and scholarship on sustainable development and climate change.
Author : Raffaele Pernice
Publisher : Routledge
ISBN 13 : 1000539482
Total Pages : 317 pages
Book Rating : 4.0/5 (5 download)
Download or read book The Urbanism of Metabolism written by Raffaele Pernice and published by Routledge. This book was released on 2022-03-17 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited book explores and promotes reflection on how the lessons of Metabolism experience can inform current debate on city making and future practice in architectural design and urban planning. More than sixty years after the Metabolist manifesto was published, the author’s original contributions highlight the persistent links between present and past that can help to re-imagine new urban futures as well as the design of innovative intra-urban relationships and spaces. The essays are written by experienced scholars and renowned academics from Japan, Australia, Europe, South Korea and the United States and expose Metabolism’s special merits in promoting new urban models and evaluate the current legacy of its architectural projects and urban design lessons. They offer a critical, intellectual, and up-to-date account of the Metabolism projects and ideas with regard to the current evolution of architectural and urbanism discourse in a global context. The collection of cross-disciplinary contributions in this volume will be of great interest to architects, architectural and urban historians, as well as academics, scholars and students in built environment disciplines and Japanese cultural studies.
Author : Dennis A. Smith
Publisher : John Wiley & Sons
ISBN 13 : 3527645292
Total Pages : 269 pages
Book Rating : 4.5/5 (276 download)
Download or read book Pharmacokinetics and Metabolism in Drug Design written by Dennis A. Smith and published by John Wiley & Sons. This book was released on 2012-09-13 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and prediction of ADMET properties. Although the previous chapter layout has been retained, substantial revisions have been made, with new topics such as pro-drugs, active metabolites and transporters covered in detail in a manner useful to the Drug Discovery scientist. The authors discuss the parameters and processes important for the absorption, distribution and retention of drug compounds in the body, plus the potential problems created by their transformation into toxic byproducts. While aimed at all those dealing professionally with the development and application of pharmaceutical substances, the readily comprehensible style makes this book equally suitable for students of pharmacy and related subjects. Uniquely comprehensive, the book relates physicochemistry and chemical structure to pharmacokinetic properties and ultimately drug efficacy and safety.
Author : Rem Koolhaas
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)
Download or read book Project Japan written by Rem Koolhaas and published by . This book was released on 2011 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolism was a movement launched in Japan that took inspiration for buildings and cities from biological systems. With interviews and commentary and hundreds of images, Project Japan unearths a history that casts new light on the key issues that both enervate and motivate architecture today.
Author : Donglu Zhang
Publisher : John Wiley & Sons
ISBN 13 : 9780470191682
Total Pages : 448 pages
Book Rating : 4.1/5 (916 download)
Download or read book Drug Metabolism in Drug Design and Development written by Donglu Zhang and published by John Wiley & Sons. This book was released on 2007-11-16 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essentials of drug metabolism vital to developing new therapeutic entities Information on the metabolism and disposition of candidate drugs is a critical part of all aspects of the drug discovery and development process. Drug metabolism, as practiced in the pharmaceutical industry today, is a complex, multidisciplinary field that requires knowledge of sophisticated analytical technologies and expertise in mechanistic and kinetic enzymology, organic reaction mechanism, pharmacokinetic analysis, animal physiology, basic chemical toxicology, preclinical pharmacology, and molecular biology. With chapters contributed by experts in their specific areas, this reference covers: * Basic concepts of drug metabolism * The role of drug metabolism in the pharmaceutical industry * Analytical techniques in drug metabolism * Common experimental approaches and protocols Drug Metabolism in Drug Design and Development emphasizes practical considerations such as the data needed, the experiments and analytical methods typically employed, and the interpretation and application of data. Chapters highlight facts, common protocols, detailed experimental designs, applications, and limitations of techniques. This is a comprehensive, hands-on reference for drug metabolism researchers as well as other professionals involved in pre-clinical drug discovery and development.
Author : William O. Gardner
Publisher : U of Minnesota Press
ISBN 13 : 1452963126
Total Pages : 272 pages
Book Rating : 4.4/5 (529 download)
Download or read book The Metabolist Imagination written by William O. Gardner and published by U of Minnesota Press. This book was released on 2020-04-14 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Japan’s postwar urban imagination through the Metabolism architecture movement and visionary science fiction authors The devastation of the Second World War gave rise to imaginations both utopian and apocalyptic. In Japan, a fascinating confluence of architects and science fiction writers took advantage of this space to begin remaking urban design. In The Metabolist Imagination, William O. Gardner explores the unique Metabolism movement, which allied with science fiction authors to foresee the global cities that would emerge in the postwar era. This first comparative study of postwar Japanese architecture and science fiction builds on the resurgence of interest in Metabolist architecture while establishing new directions for exploration. Gardner focuses on how these innovators created unique versions of shared concepts—including futurity, megastructures, capsules, and cybercities—making lasting contributions that resonate with contemporary conversations around cyberpunk, climate change, anime, and more. The Metabolist Imagination features original documentation of collaborations between giants of postwar Japanese art and architecture, such as the landmark 1970 Osaka Expo. It also provides the most sustained English-language discussion to date of the work of Komatsu Sakyō, considered one of the “big three” authors of postwar Japanese science fiction. These studies are underscored by Gardner’s insightful approach—treating architecture as a form of speculative fiction while positioning science fiction as an intervention into urban design—making it a necessary read for today’s visionaries.
Author : Judit Ovadi
Publisher : Springer
ISBN 13 :
Total Pages : 268 pages
Book Rating : 4.3/5 (91 download)
Download or read book Cell Architecture and Metabolic Channeling written by Judit Ovadi and published by Springer. This book was released on 1995-09-20 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about enzyme organization in matrix spaces of the cell, which is a prerequisite of metabolite channelling, a process which facilitates substrate delivery in metabolic pathways. The structural, functional and regulatory consequences as well as physiological significance of these processes are reviewed on the bases of theoretical and experimental results carried out at different levels of complexity and organization.
Author : Rahul Bhadouria
Publisher : Springer Nature
ISBN 13 : 303129422X
Total Pages : 362 pages
Book Rating : 4.0/5 (312 download)
Download or read book Urban Metabolism and Climate Change written by Rahul Bhadouria and published by Springer Nature. This book was released on 2023-05-23 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a basic understanding and state-of-the-art of urban metabolism. Urban centres are increasingly challenged by population increase and the resultant environmental concerns including the urban sprawl and climate change. Different patterns of urbanization contribute to the changing climate via. differences in their urban metabolism represented by energy and matter. Urban metabolic studies in terms of energy and material inflows, outflows, and stocks can be associated with traditional evaluation techniques to help assess the magnitude and potential effects of variety of environmental challenges the world is facing today. Urban centres are critical real time observatories that indicate the impact anthropogenic activities have on global biogeochemical cycles. Urban processes have significant and lasting impacts on the global carbon budget. The technological and infrastructural advancements have fuelled an increase in urban inputs and outputs of material and energy. Therefore, more sustainable approaches need to be adopted in changing scenarios for urban planning, particularly for sustainable resource utilization and better waste management practices. The book emphasises on the sustainability in urban metabolism, sustainable urban planning, ecosystem services, and disaster resilience to provide an interdisciplinary understanding of urban metabolism. The book also identifies an urgent need to develop new methodological approaches for real time and reliable evaluation of urban metabolism.
Author : Library of Congress
Publisher :
ISBN 13 :
Total Pages : 1396 pages
Book Rating : 4.:/5 (7 download)
Download or read book Library of Congress Subject Headings written by Library of Congress and published by . This book was released on 2004 with total page 1396 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : William F. Gilreath
Publisher : Springer Science & Business Media
ISBN 13 : 9781402074165
Total Pages : 220 pages
Book Rating : 4.0/5 (741 download)
Download or read book Computer Architecture: A Minimalist Perspective written by William F. Gilreath and published by Springer Science & Business Media. This book was released on 2003-03-31 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The one instruction set computer (OISC) is the ultimate reduced instruction set computer (RISC). In OISC, the instruction set consists of only one instruction, and then by composition, all other necessary instructions are synthesized. This is an approach completely opposite to that of a complex instruction set computer (CISC), which incorporates complex instructions as microprograms within the processor. Computer Architecture: A Minimalist Perspective examines computer architecture, computability theory, and the history of computers from the perspective of one instruction set computing - a novel approach in which the computer supports only one, simple instruction. This bold, new paradigm offers significant promise in biological, chemical, optical, and molecular scale computers. Features include: · Provides a comprehensive study of computer architecture using computability theory as a base. · Provides a fresh perspective on computer architecture not found in any other text. · Covers history, theory, and practice of computer architecture from a minimalist perspective. Includes a complete implementation of a one instruction computer. · Includes exercises and programming assignments. Computer Architecture: A Minimalist Perspective is designed to meet the needs of a professional audience composed of researchers, computer hardware engineers, software engineers computational theorists, and systems engineers. The book is also intended for use in upper division undergraduate students and early graduate students studying computer architecture or embedded systems. It is an excellent text for use as a supplement or alternative in traditional Computer Architecture Courses, or in courses entitled "Special Topics in Computer Architecture."
