Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Metabolic And Vascular Imaging Biomarkers For Brain Aging And Alzheimers Disease
Download Metabolic And Vascular Imaging Biomarkers For Brain Aging And Alzheimers Disease full books in PDF, epub, and Kindle. Read online Metabolic And Vascular Imaging Biomarkers For Brain Aging And Alzheimers Disease ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Metabolic and Vascular Imaging Biomarkers for Brain Aging and Alzheimer’s Disease by : Ai-Ling Lin
Download or read book Metabolic and Vascular Imaging Biomarkers for Brain Aging and Alzheimer’s Disease written by Ai-Ling Lin and published by Frontiers Media SA. This book was released on 2020-08-10 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Metabolic and Vascular Imaging Biomarkers for Brain Aging and Alzheimer's Disease by : Ai-Ling Lin
Download or read book Metabolic and Vascular Imaging Biomarkers for Brain Aging and Alzheimer's Disease written by Ai-Ling Lin and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Book Synopsis Imaging in Alzheimer's Disease and Other Dementias, An Issue of Neuroimaging Clinics by : Alison D. Murray
Download or read book Imaging in Alzheimer's Disease and Other Dementias, An Issue of Neuroimaging Clinics written by Alison D. Murray and published by Elsevier Health Sciences. This book was released on 2012-09-14 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dementia is a massive and increasing global problem, with the current prevalence anticipated to double every 20 years as people live longer. Neuroimaging in dementia is recommended by most clinical guidelines and its role has traditionally been to exclude a mass lesion, rather than to support a specific diagnosis. All radiologists will be aware of a steady rise in the number of requests for brain imaging in old people, but what can imaging reliably tell us and what kind of imaging should we use? In affluent societies we now have a range of structural and molecular brain imaging techniques at our disposal, with specific ligands and sophisticated image analysis techniques now available for clinical use. However, we have difficulty justifying which patients to scan, using which modality and when. We know that Alzheimer's disease is the most common neuropathology contributing to a diagnosis of Alzheimer's disease but we also know from large post-mortem studies that most brain pathology in those who have died with a diagnosis of dementia is mixed. Thus understanding different diseases that can cause dementia, how these co-exist or interact and appreciating that not all dementia is Alzheimer's disease is important. Equally important is awareness of individual differences in response to a neuropathological burden and what factors provide resilience against dementia that might be maximized to reduce or postpone its impact. This issue draws together contributions from experts in their fields to provide clarity to the topic in a comprehensive collection of articles.
Book Synopsis Understanding Emerging Biomarkers and Lifestyle Factors in Aging and Alzheimer Disease by : Stephanie Ann Schultz
Download or read book Understanding Emerging Biomarkers and Lifestyle Factors in Aging and Alzheimer Disease written by Stephanie Ann Schultz and published by . This book was released on 2020 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Age-related cognitive decline and pathological brain changes are a widespread and growing public health issue. Several environmental factors, including engagement in physical activity and personality, have been shown to have potential protective effects in slowing cognitive decline and preserving healthy brain aging. However, the underlying mechanisms providing exercise- or personality-induced resilience to aging and disease remains largely unknown. Importantly, there has been an emergence of several novel biomarkers to study healthy brain aging and age-related neurodegenerative diseases including in vivo assessments of tau burden and brain metabolism via positron emission tomography (PET) imaging and neurofilament light chain (NfL), a marker of neurodegeneration, via Age-related cognitive decline and pathological brain changes are a widespread and growing public health issue. Several environmental factors, including engagement in physical activity and personality, have been shown to have potential protective effects in slowing cognitive decline and preserving healthy brain aging. However, the underlying mechanisms providing exercise- or personality-induced resilience to aging and disease remains largely unknown. Importantly, there has been an emergence of several novel biomarkers to study healthy brain aging and age-related neurodegenerative diseases including in vivo assessments of tau burden and brain metabolism via positron emission tomography (PET) imaging and neurofilament light chain (NfL), a marker of neurodegeneration, via blood-based biomarkers. During the first part of my thesis research, I examined these emerging biomarkers within healthy aging and AD cohorts at Washington University, in the Australian Imaging, Biomarkers, and Lifestyle (AIBL) cohort, and in the Dominantly Inherited Alzheimer Network (DIAN) observational study (Chapters 2 - 5). For the second part of my thesis research, I first used my new knowledge and experience with these biomarkers to characterize and determine the influence of physical activity on cerebral glucose metabolism (Chapter 6). Next, to better translate these findings to an exercise intervention in the future, I further completed a pilot study to determine feasibility and validity of performing a submaximal exercise protocol in a diverse US population (Chapter 7). For the third part of my thesis research, I discovered a cross-sectional association between personality traits and neurofibrillary tangle pathology. Taken together, the results from my thesis suggest utility in all three emerging biomarkers examined (tau-PET, blood-based NfL, and multi-tracer brain metabolism PET) for monitoring and understanding complex changes associated with brain aging and disease. Additionally, this thesis research adds to the current understanding of the potential role of increased physical activity in preservation of glycolytic metabolism in the aging brain and increased risk of AD-related tau pathophysiology in neurotic personality traits. Further research extending these findings to longitudinal studies are needed to help determine directionality of the observed effects.
Book Synopsis Imaging and the Aging Brain, Volume 1097 by : Mony J. de Leon
Download or read book Imaging and the Aging Brain, Volume 1097 written by Mony J. de Leon and published by Wiley-Blackwell. This book was released on 2007-04-02 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in imaging are occurring at a brisk pace, and imaging techniques have great potential to act as pre-symptomatic predictors of disease as well as to chart the course of a disease. Neuroimaging has greatly advanced the understanding of brain function and its relationship to the anatomical substrate. This volume brings together internationally renowned imaging scientists, those studying the aging brain, industry experts, and clinicians to jointly examine the most current methods and their application to brain physiology, behavior, and age-related diseases. These reports explore new technologies, data from recent neuroimaging initiatives, and translational research applications. Topics covered include (1) in vivo imaging of molecules, cells, and networks throughout the lifespan, (2) cutting edge imaging technologies and studies of the physiology of aging, (3) translational application of neuroimaging, and (4) emerging technologies in the private sector. This volume is the proceedings of a meeting that celebrated the 25th anniversary of the American Federation for Aging Research and its longstanding history of philanthropy in the area of aging research. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership for more information about becoming a member.
Book Synopsis Biomarkers in Alzheimer's Disease by : Tapan Khan
Download or read book Biomarkers in Alzheimer's Disease written by Tapan Khan and published by Academic Press. This book was released on 2016-08-02 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers in Alzheimer’s Disease provides a comprehensive overview of all modalities of Alzheimer’s disease biomarkers, including neuroimaging, cerebrospinal fluid, genomic, and peripheral systems. Each chapter integrates molecular/cellular abnormality due to Alzheimer’s disease and technological advancement of biomarkers techniques. The book is ideal for clinical neuroscience and molecular/cellular neuroscience researchers, psychiatrists, and allied healthcare practitioners involved in the diagnosis and management of patients with cognitive impairment and Alzheimer’s disease, and for differential diagnosis of Alzheimer’s disease with other non-Alzheimer’s dementia. Presents a comprehensive overview detailing all modalities of Alzheimer’s disease biomarkers Written for neuroscience researchers and clinicians studying or treating patients with Alzheimer’s Disease Integrates, in each chapter, the molecular/cellular abnormality due to Alzheimer’s disease and the technological advancement of biomarkers techniques
Book Synopsis Neuroanatomy and Pathology of Sporadic Alzheimer's Disease by : Heiko Braak
Download or read book Neuroanatomy and Pathology of Sporadic Alzheimer's Disease written by Heiko Braak and published by Springer. This book was released on 2014-12-11 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail
Book Synopsis Neuroimaging in Dementia by : Frederik Barkhof
Download or read book Neuroimaging in Dementia written by Frederik Barkhof and published by Springer Science & Business Media. This book was released on 2011-02-11 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with cognitive decline. It sets out the key clinical and imaging features of the various causes of dementia and directs the reader from clinical presentation to neuroimaging and on to an accurate diagnosis whenever possible. After an introductory chapter on the clinical background, the available "toolbox" of structural and functional neuroimaging techniques is reviewed in detail, including CT, MRI and advanced MR techniques, SPECT and PET, and image analysis methods. The imaging findings in normal ageing are then discussed, followed by a series of chapters that carefully present and analyze the key findings in patients with dementias. Throughout, a practical approach is adopted, geared specifically to the needs of clinicians (neurologists, radiologists, psychiatrists, geriatricians) working in the field of dementia, for whom this book will prove an invaluable resource.
Book Synopsis Cerebrospinal Fluid Biomarkers by : Charlotte E. Teunissen
Download or read book Cerebrospinal Fluid Biomarkers written by Charlotte E. Teunissen and published by Humana. This book was released on 2022-05-19 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the latest methods used in clinical neurochemistry laboratories for both clinical practice and research. Chapters in this book discuss topics such as techniques for cerebrospinal fluid (CSF) collection, pre-analytical processing, and basic CSF analysis; an examination of biomarkers including ELISA and automated immunochemical assays for amyloid and tau markers for Alzheimer’s disease; the analysis of neurofilaments by digital ELISA; and an example of successful novel immunoassay development. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, Cerebrospinal Fluid Biomarkers is a valuable resource for clinicians and researchers to use in CSF labs and CSF courses.
Book Synopsis Vascular Cognitive Impairment in Clinical Practice by : Lars-Olof Wahlund
Download or read book Vascular Cognitive Impairment in Clinical Practice written by Lars-Olof Wahlund and published by . This book was released on 2009 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gives a broad clinical perspective on vascular cognitive impairment, and creates a foundation for the implementation of good dementia care.
Book Synopsis Heterogeneity of Alzheimer’s Disease by : Francois Boller
Download or read book Heterogeneity of Alzheimer’s Disease written by Francois Boller and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term "Alzheimer's disease" is currently used to refer to senile and also presenile dementia, but the heterogeneity of this disorder is demonstrated in many of its aspects. This is of great theoretical interest, and with the appearance of new therapeutic interventions, it may well also start to have very significant practical importance. To shed some light on the debate, the Fondation Ipsen organized an international symposium which took place on April 6, 1992. This volume contains the proceedings of this meeting, which was attended by researchers in epidemiology, clinical neurology and geriatrics, neuropsychology, neuropathology, molecular biology, and genetics.
Book Synopsis Diseases of the Brain, Head and Neck, Spine 2020–2023 by : Juerg Hodler
Download or read book Diseases of the Brain, Head and Neck, Spine 2020–2023 written by Juerg Hodler and published by Springer Nature. This book was released on 2020-02-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.
Book Synopsis Vascular Dementia by : Sarah R. Jacobsen
Download or read book Vascular Dementia written by Sarah R. Jacobsen and published by Nova Biomedical Books. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular dementia is the second most common form of dementia after Alzheimer's disease in older adults. The term refers to a group of syndromes caused by different mechanisms all resulting in vascular lesions in the brain. Early detection and accurate diagnosis are important, as vascular dementia is at least partially preventable. Risk factors for vascular dementia include hypertension, smoking, hypercholesterolemia, diabetes mellitus, and cardiovascular and cerebrovascular disease. This book presents current research from across the globe in the study of vascular dementia, including GRK2 over-expression in the context of early Alzheimer disease pathogenesis; vitamin deficiencies and vascular dementia; biofluid markers as potential markers for vascular dementia; and the epidemiology of vascular dementia.
Book Synopsis Type 2 Diabetes and Dementia by : Velandai Srikanth
Download or read book Type 2 Diabetes and Dementia written by Velandai Srikanth and published by Academic Press. This book was released on 2018-02-09 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science in the field, with an emphasis on the display of neuroimaging and neuropathology. It contains contributions from world experts, and is ideal for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine and endocrinology. Presents a comprehensive overview that details the relationship between diabetes, dementia and the future of medicine and therapeutics Written for researchers and clinicians in neurology, neuroscience, geriatric medicine and endocrinology Includes topics ranging from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment, prevention strategies and therapeutic applications
Book Synopsis Cerebral Small Vessel Disease by : Leonardo Pantoni
Download or read book Cerebral Small Vessel Disease written by Leonardo Pantoni and published by Cambridge University Press. This book was released on 2014-05 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.
Book Synopsis Imaging Acute Neurologic Disease by : Massimo Filippi
Download or read book Imaging Acute Neurologic Disease written by Massimo Filippi and published by Cambridge University Press. This book was released on 2014-09-11 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of best practice in using diagnostic imaging in acute neurologic conditions. The symptom-based approach guides the choice of the available imaging tools for efficient, accurate, and cost-effective diagnosis. Effective examination algorithms integrate neurological and imaging concepts with the practical demands and constraints of emergency care.
Book Synopsis Cognitive Changes and the Aging Brain by : Kenneth M. Heilman
Download or read book Cognitive Changes and the Aging Brain written by Kenneth M. Heilman and published by Cambridge University Press. This book was released on 2019-12-05 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the changes in the brain and in cognitive functions that occur with aging in the absence of a neurological, psychiatric, or medical disease. It discusses aging-related changes in many brain functions, including memory, language, sensory perception, motor function, creativity, attention, executive functions, emotions and mood. The neural mechanisms that may account for specific aging-related changes in cognition, perception and behavior are explored, as well as the means by which aging-related cognitive decrements can be managed and possibly ameliorated. Consequently, this book will be of value to clinicians, including neurologists, psychiatrists, geriatricians, primary care physicians, psychologists and speech-language pathologists. In addition, researchers and graduate students who want to learn about the aging brain will find this an indispensable guide.
