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Medical Biomethods Handbook
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Book Synopsis Medical BioMethods Handbook by : John M. Walker
Download or read book Medical BioMethods Handbook written by John M. Walker and published by Springer Science & Business Media. This book was released on 2007-10-09 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: John Walker and Ralph Rapley have collected a wide-ranging group of molecular and biochemical techniques that are the most frequently used in medical and clinical research, especially diagnostics. The authors-well-established investigators who run their own research programs and use the methods on a regular basis-outline the practical procedures for using them and describe a variety of pertinent applications. Among the technologies presented are southern and western blotting, electrophoresis, PCR, cDNA and protein microarrays, liquid chromatography, in situ hybridization, karyotyping, flow cytometry, bioinformatics, genomics, and ribotyping. The applications include assays for mutation detection, mRNA analysis, chromosome translocations, inborn errors of metabolism, protein therapeutics, and gene therapy.
Book Synopsis Molecular Biomethods Handbook by : John M. Walker
Download or read book Molecular Biomethods Handbook written by John M. Walker and published by Springer Science & Business Media. This book was released on 2008-09-04 with total page 1148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in the biosciences have led to a range of powerful new technologies, particularly nucleic acid, protein and cell-based methodologies. The most recent insights have come to affect how scientists investigate and define cellular processes at the molecular level. This book expands upon the techniques included in the first edition, providing theory, outlines of practical procedures, and applications for a range of techniques. Written by a well-established panel of research scientists, the book provides an up-to-date collection of methods used regularly in the authors’ own research programs.
Book Synopsis Molecular Biomethods Handbook by : John M. Walker
Download or read book Molecular Biomethods Handbook written by John M. Walker and published by Springer Science & Business Media. This book was released on 2008-11-04 with total page 1105 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in the biosciences have led to a range of powerful new technologies, particularly nucleic acid, protein and cell-based methodologies. The most recent insights have come to affect how scientists investigate and define cellular processes at the molecular level. This book expands upon the techniques included in the first edition, providing theory, outlines of practical procedures, and applications for a range of techniques. Written by a well-established panel of research scientists, the book provides an up-to-date collection of methods used regularly in the authors’ own research programs.
Book Synopsis Introduction to Reference Sources in the Health Sciences by : Jeffrey T. Huber
Download or read book Introduction to Reference Sources in the Health Sciences written by Jeffrey T. Huber and published by American Library Association. This book was released on 2014-04-22 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prepared in collaboration with the Medical Library Association, this completely updated, revised, and expanded edition lists classic and up-to-the-minute print and electronic resources in the health sciences, helping librarians find the answers that library users seek.
Book Synopsis Systematic Evaluation of the Mouse Eye by : Richard S. Smith
Download or read book Systematic Evaluation of the Mouse Eye written by Richard S. Smith and published by CRC Press. This book was released on 2001-12-20 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completion of the first phase of the Human Genome Project has presented scientists with a mountain of new information. The availability of all human genes and their locations is exciting, but their mechanisms of action and interaction with other genes are often unknown. Certain variations in the environment and characteristics of human genes make i
Book Synopsis Genetically Engineered Mice Handbook by : John P. Sundberg
Download or read book Genetically Engineered Mice Handbook written by John P. Sundberg and published by CRC Press. This book was released on 2016-04-19 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: While mice have always been highly popular laboratory subjects, their suitability for genetic engineering has solidified their position as today's lab animal model of choice. However, their increased use in genetic studies has created a demand for input on phenotyping that is not always easily met. To improve the flow of information on the pathology of mice with spontaneous or genetically engineered mutations, prominent researchers organized a series of meetings. Recognizing other needs, the organizers gradually broadened their focus, until finally they expanded to provide an overview of the entire field of genetically engineered models. The Genetically Engineered Mice Handbook is an extension of those meetings. It offers an introduction for those entering into this area of research, while also serving as a resource for those presently employing mice as laboratory models. Highly comprehensive, this volume covers pertinent aspects of genetically engineered mice, including the use of models for developmental biology and the monitoring of laboratory colonies. With contributions from nearly five-dozen leading researchers, the text presents systematic approaches for analyzing mutant mice for specific medical applications, details a variety of methods for creating mutants and includes information that is particularly hard to access dealing with legal responsibilities. This essential reference examines commonly used traditional, as well as emerging, technologies To address the purpose of the original meeting, the Genetically Engineered Mice Handbook directs researchers to the best public websites, and offers instruction on how to use them. In the past, as their work dictated, researchers would seek out experts on particular organ systems. Now groups of experts work together to generate these websites, providing the latest data as well as discussions over points of debate. These sites do not eliminate the need for a trained pathologist, but they do provide reference materials for those lacking expertise in particular anatomic structures. They also offer much greater numbers of examples than are available in print, from which biomedical researchers can draw.
Book Synopsis Handbook of Biomaterial Properties by : William Murphy
Download or read book Handbook of Biomaterial Properties written by William Murphy and published by Springer. This book was released on 2016-06-11 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides tabular and text data relating to normal and diseased tissue materials and materials used in medical devices. Comprehensive and practical for students, researchers, engineers, and practicing physicians who use implants, this book considers the materials aspects of both implantable materials and natural tissues and fluids. Examples of materials and topics covered include titanium, elastomers, degradable biomaterials, composites, scaffold materials for tissue engineering, dental implants, sterilization effects on material properties, metallic alloys, and much more. Each chapter author considers the intrinsic and interactive properties of biomaterials, as well as their appropriate applications and historical contexts. Now in an updated second edition, this book also contains two new chapters on the cornea and on vocal folds, as well as updated insights, data, and citations for several chapters.
Book Synopsis Translating Healthcare Through Intelligent Computational Methods by : C. Ram Kumar
Download or read book Translating Healthcare Through Intelligent Computational Methods written by C. Ram Kumar and published by Springer Nature. This book was released on 2023-06-07 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides information on interdependencies of medicine and telecommunications engineering and how Covid exemplifies how the two must rely on each other to effectively function in this era. The book discusses new techniques for medical service improvisation such as clear cut views on medical technologies. The authors provide chapters on processing of medical amenities using medical images, the importance of data and information technology in medicine, and machine learning and artificial intelligence in healthcare. Authors include researchers, academics, and professionals in the field of communications engineering with a variety of perspectives.
Book Synopsis Basic Science Methods for Clinical Researchers by : Morteza Jalali
Download or read book Basic Science Methods for Clinical Researchers written by Morteza Jalali and published by Academic Press. This book was released on 2017-03-31 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow’s clinician scientists and future leaders in discovery science. Serves as a helpful guide for clinical researchers who lack a conventional science background Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)
Book Synopsis Sensor Technologies by : Michael J. McGrath
Download or read book Sensor Technologies written by Michael J. McGrath and published by Apress. This book was released on 2014-01-23 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sensor Technologies: Healthcare, Wellness and Environmental Applications explores the key aspects of sensor technologies, covering wired, wireless, and discrete sensors for the specific application domains of healthcare, wellness and environmental sensing. It discusses the social, regulatory, and design considerations specific to these domains. The book provides an application-based approach using real-world examples to illustrate the application of sensor technologies in a practical and experiential manner. The book guides the reader from the formulation of the research question, through the design and validation process, to the deployment and management phase of sensor applications. The processes and examples used in the book are primarily based on research carried out by Intel or joint academic research programs. “Sensor Technologies: Healthcare, Wellness and Environmental Applications provides an extensive overview of sensing technologies and their applications in healthcare, wellness, and environmental monitoring. From sensor hardware to system applications and case studies, this book gives readers an in-depth understanding of the technologies and how they can be applied. I would highly recommend it to students or researchers who are interested in wireless sensing technologies and the associated applications.” Dr. Benny Lo Lecturer, The Hamlyn Centre, Imperial College of London “This timely addition to the literature on sensors covers the broad complexity of sensing, sensor types, and the vast range of existing and emerging applications in a very clearly written and accessible manner. It is particularly good at capturing the exciting possibilities that will occur as sensor networks merge with cloud-based ‘big data’ analytics to provide a host of new applications that will impact directly on the individual in ways we cannot fully predict at present. It really brings this home through the use of carefully chosen case studies that bring the overwhelming concept of 'big data' down to the personal level of individual life and health.” Dermot Diamond Director, National Centre for Sensor Research, Principal Investigator, CLARITY Centre for Sensor Web Technologies, Dublin City University "Sensor Technologies: Healthcare, Wellness and Environmental Applications takes the reader on an end-to-end journey of sensor technologies, covering the fundamentals from an engineering perspective, introducing how the data gleaned can be both processed and visualized, in addition to offering exemplar case studies in a number of application domains. It is a must-read for those studying any undergraduate course that involves sensor technologies. It also provides a thorough foundation for those involved in the research and development of applied sensor systems. I highly recommend it to any engineer who wishes to broaden their knowledge in this area!" Chris Nugent Professor of Biomedical Engineering, University of Ulster
Book Synopsis Molecular Diagnostics in Dermatology and Dermatopathology by : Michael J. Murphy
Download or read book Molecular Diagnostics in Dermatology and Dermatopathology written by Michael J. Murphy and published by Springer Science & Business Media. This book was released on 2011-03-24 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Diagnostics in Dermatology and Dermatopathology presents the basics of molecular biology and molecular diagnostic methods most commonly used in the clinical laboratory, with an emphasis on the concepts and testing most relevant to dermatological diseases. Topics include the integration of newer diagnostic and prognostic techniques with ‘traditional’ histologic approaches, and discussions of regulatory, ethical, legal, economic issues and ‘newer’ technologies. This important diagnostic tool outlines the clinically relevant uses (i.e.; diagnostic, staging and/or prognostic) applications of these techniques in the field of dermatology. Molecular studies that investigate the pathogenesis of skin diseases will be excluded, unless they also have a direct diagnostic utility. The book will be of interest to practicing pathologists, dermatology and pathology residents, dermatologists, and dermatopathologists.
Book Synopsis Introduction to Instrumentation in Life Sciences by : Prakash Singh Bisen
Download or read book Introduction to Instrumentation in Life Sciences written by Prakash Singh Bisen and published by CRC Press. This book was released on 2012-09-26 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Instrumentation is central to the study of physiology and genetics in living organisms, especially at the molecular level. Numerous techniques have been developed to address this in various biological disciplines, creating a need to understand the physical principles involved in the operation of research instruments and the parameters required in using them. Introduction to Instrumentation in Life Sciences fills this need by addressing different aspects of tools that hold the keys to cutting-edge research and innovative applications, from basic techniques to advanced instrumentation. The text describes all topics so even beginners can easily understand the theoretical and practical aspects. Comprehensive chapters encompass well-defined methodology that describes the instruments and their corresponding applications in different scientific fields. The book covers optical and electron microscopy; micrometry, especially in microbial taxonomy; pH meters and oxygen electrodes; chromatography for separation and purification of products from complex mixtures; spectroscopic and spectrophotometric techniques to determine structure and function of biomolecules; preparative and analytical centrifugation; electrophoretic techniques; x-ray microanalysis including crystallography; applications of radioactivity, including autoradiography and radioimmunoassays; and fermentation technology and subsequent separation of products of interest. The book is designed to serve a wide range of students and researchers in diversified fields of life sciences: pharmacy, biotechnology, microbiology, biochemistry, and environmental sciences. It introduces different aspects of basic experimental methods and instrumentation. The book is unique in its broad subject coverage, incorporating fundamental techniques as well as applications of modern molecular and proteomic tools that are the basis for state-of-the-art research. The text emphasizes techniques encountered both in practical classes and in high-throughput environments used in modern industry. As a further aid to students, the authors provide well-illustrated diagrams to explain the principles and theories behind the instruments described.
Book Synopsis Dermatology E-Book by : Jean L. Bolognia
Download or read book Dermatology E-Book written by Jean L. Bolognia and published by Elsevier Health Sciences. This book was released on 2012-06-08 with total page 2808 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dermatology, edited by world authorities Jean L. Bolognia, MD, Joseph L. Jorizzo, MD, and Julie V. Schaffer, MD, is an all-encompassing medical reference book that puts the latest practices in dermatologic diagnosis and treatment at your fingertips. It delivers more comprehensive coverage of basic science, clinical practice, pediatric dermatology, and dermatologic surgery than you’ll find in any other source. Whether you’re a resident or an experienced practitioner, you’ll have the in-depth, expert, up-to-the-minute answers you need to overcome any challenge you face in practice. Find answers fast with a highly user-friendly, "easy-in-easy-out" format and a wealth of tables and algorithms for instant visual comprehension. Get full exposure to core knowledge with coverage of dermatology’s entire spectrum of subspecialties. See just the essential information with "need-to-know" basic science information and key references. Expedite decision making and clarify complex concepts with logical tables, digestible artwork, and easy-to-grasp schematics. Visualize more of the conditions you see in practice with over 3500 illustrations, of which over 1,400 are new: 1,039 clinical images, 398 pathology slides, and 152 schematics. Stay at the forefront of your field with updated treatment methods throughout, as well as an increased focus on patients with skin of color. Get an enhanced understanding of the foundations of dermatology in pathology, the clinical setting, and dermoscopy with a completely rewritten introductory chapter. Better comprehend the clinical-pathological relationship of skin disease with increased histologic coverage. Bolognia’s Dermatology is the ultimate multimedia reference for residents in training AND the experienced practitioner.
Book Synopsis Laboratory Protocols in Applied Life Sciences by : Prakash Singh Bisen
Download or read book Laboratory Protocols in Applied Life Sciences written by Prakash Singh Bisen and published by CRC Press. This book was released on 2014-02-26 with total page 1812 pages. Available in PDF, EPUB and Kindle. Book excerpt: As applied life science progresses, becoming fully integrated into the biological, chemical, and engineering sciences, there is a growing need for expanding life sciences research techniques. Anticipating the demands of various life science disciplines, Laboratory Protocols in Applied Life Sciences explores this development. This book covers a wide spectrum of areas in the interdisciplinary fields of life sciences, pharmacy, medical and paramedical sciences, and biotechnology. It examines the principles, concepts, and every aspect of applicable techniques in these areas. Covering elementary concepts to advanced research techniques, the text analyzes data through experimentation and explains the theory behind each exercise. It presents each experiment with an introduction to the topic, concise objectives, and a list of necessary materials and reagents, and introduces step-by-step, readily feasible laboratory protocols. Focusing on the chemical characteristics of enzymes, metabolic processes, product and raw materials, and on the basic mechanisms and analytical techniques involved in life science technological transformations, this text provides information on the biological characteristics of living cells of different origin and the development of new life forms by genetic engineering techniques. It also examines product development using biological systems, including pharmaceutical, food, and beverage industries. Laboratory Protocols in Applied Life Sciences presents a nonmathematical account of the underlying principles of a variety of experimental techniques in disciplines, including: Biotechnology Analytical biochemistry Clinical biochemistry Biophysics Molecular biology Genetic engineering Bioprocess technology Industrial processes Animal Plant Microbial biology Computational biology Biosensors Each chapter is self-contained and written in a style that helps students progress from basic to advanced techniques, and eventually design and execute their own experiments in a given field of biology.
Download or read book Molecular Biology written by Nancy Craig and published by Oxford University Press. This book was released on 2014-05 with total page 945 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Molecular Biology' offers a fresh, distinctive approach to the study of molecular biology. With its focus on key principles, its emphasis on the commonalities that exist between the three kingdoms of life, and its integrated approach throughout, it is the perfect companion to any molecular biology course.
Book Synopsis Gene Discovery for Disease Models by : Weikuan Gu
Download or read book Gene Discovery for Disease Models written by Weikuan Gu and published by John Wiley & Sons. This book was released on 2011-03-03 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with new paradigms on the mutation discovery in the post-genome era. The completion of human and other genome sequencing, along with other new technologies, such as mutation analysis and microarray, has dramatically accelerated the progress in positional cloning of genes from mutated models. In 2002, the Mouse Genome Sequencing Consortium stated that “The availability of an annotated mouse genome sequence now provides the most efficient tool yet in the gene hunter's toolkit. One can move directly from genetic mapping to identification of candidate genes, and the experimental process is reduced to PCR amplification and sequencing of exons and other conserved elements in the candidate interval. With this streamlined protocol, it is anticipated that many decades-old mouse mutants will be understood precisely at the DNA level in the near future.” The implication of such a statement should be similar to the identification of mutated genes from human diseases and animal models, when genome sequencing is completed for them. More than five years have passed, but genes in many human diseases and animal models have not yet been identified. In some cases, the identification of the mutated genes has been a bottleneck, because the genetic mechanism holds the key to understand the basis of the diseases. However, an integrative strategy, which is a combination of genetic mapping, genome resources, bioinformatics tools, and high throughput technologies, has been developed and tested. The classic paradigm of positional cloning has evolved with completely new concepts of genomic cloning and protocols. This book describes new concepts of gene discovery in the post-genome era and the use of streamlined protocols to identify genes of interest. This book helps identify not only large insertions/deletions but also single nucleotide mutations or polymorphisms that regulate quantitative trait loci (QTL).
Book Synopsis Cell and Tissue Based Molecular Pathology E-Book by : Raymond R. Tubbs
Download or read book Cell and Tissue Based Molecular Pathology E-Book written by Raymond R. Tubbs and published by Elsevier Health Sciences. This book was released on 2008-09-22 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume in the Foundations in Diagnostic Pathology Series packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, clinically valid, and diagnostically important applications today and in the near future, you can be assured you’re getting the most up-to-date, authoritative coverage available. Its pragmatic, well-organized approach, nearly 250 full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice! Offers detailed discussions on today’s technologies to help you select the best test for case evaluation. Presents recognized molecular pathologists who convey the most current information, keeping you on the cusp of your field. Features nearly 250 full-color illustrations that present important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Uses a consistent, user-friendly format, including at-a-glance boxes and tables for easy reference.
