Mechanized Mesoporous Inorganic Nanoparticles for Drug Delivery Applications

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Publisher :
ISBN 13 :
Total Pages : 138 pages
Book Rating : 4.:/5 (86 download)

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Book Synopsis Mechanized Mesoporous Inorganic Nanoparticles for Drug Delivery Applications by : Min Xue

Download or read book Mechanized Mesoporous Inorganic Nanoparticles for Drug Delivery Applications written by Min Xue and published by . This book was released on 2013 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: The research covered in this dissertation is described in six chapters. The first two chapters focus on the design of supramolecular nanovalves on mesoporous silica and silicon materials to form drug delivery systems. These systems are capable of autonomously releasing drug molecules in vitro. The third chapter describes size-selective nanovalves that are able to control the release of both large and small molecules. These nanovalves are constructed on mesoporous silica materials with 6.5 nm pores. The fourth chapter demonstrates two experimental methods, dynamic fluorescence anisotropy and rigidochromism spectroscopy, for probing the properties of the microenvironment inside the mesopores of mesoporous silica nanoparticles. In the fifth chapter of this dissertation, the design and operation of a chemical amplifier based on enzyme-encapsulated mesoporous silica are shown. This system employs a pH-responsive nanogate assembly to control the access to the encapsulated enzyme. It is the first example of a chemical amplifier that is activated by and also amplifies the same type of reaction. The last chapter describes the spectroscopic consequences of the excited state mixed valence in a binuclear copper complex using a neighboring orbital model. The copper complex represents a new class of excited state mixed valence compounds, where the coupling of two equivalent charge-baring units is mediated through a copper-iodine cluster. The result from the simple neighboring orbital approach is supported by resonance Raman spectroscopy and Gaussian calculations.

Design, Synthesis, Multifunctionalization and Biomedical Applications of Multifunctional Mesoporous Silica-Based Drug Delivery Nanosystems

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Publisher : Springer
ISBN 13 : 3662486229
Total Pages : 100 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Design, Synthesis, Multifunctionalization and Biomedical Applications of Multifunctional Mesoporous Silica-Based Drug Delivery Nanosystems by : Yu Chen

Download or read book Design, Synthesis, Multifunctionalization and Biomedical Applications of Multifunctional Mesoporous Silica-Based Drug Delivery Nanosystems written by Yu Chen and published by Springer. This book was released on 2015-10-14 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis reports on essential advances in the design, synthesis and biomedical applications of multifunctional Mesoporous Silica Nanoparticles (MSNs). It provides several examples of multifunctional MSN-based drug delivery nanosystems and demonstrates successful synergistic cancer therapies combining MSNs and high-intensity focused ultrasound. The book will especially be of interest to researchers and graduate students in the fields of biomaterials, biology, chemistry, medicine and the life sciences who are working to develop new methods and technologies to combat cancer.

Mesoporous Materials for Drug Delivery and Theranostics

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Publisher : MDPI
ISBN 13 : 3039439391
Total Pages : 204 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis Mesoporous Materials for Drug Delivery and Theranostics by : Valentina Cauda

Download or read book Mesoporous Materials for Drug Delivery and Theranostics written by Valentina Cauda and published by MDPI. This book was released on 2020-12-17 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesoporous materials are capturing great interest thanks to their exceptional surface area, uniform and tunable pore size, ease surface functionalization, thus enabling broad series of intervention in the field of nanomedicine. Since many years, these aspects foster a deep investigation on mesoporous nanoparticles, to design and fabricate biocompatible, smart and stimuli-responsive nanotools for controlled drug- or gene-delivery, theranostics applications, in particular for cancer therapy, and tissue engineering. This Book is thus dedicated to the most recent advances in the field, collecting research papers and reviews. It spans from the synthesis and characterization of the mesoporous material, especially those made of silica, silicon and bioactive glasses, to their functionalization with smart gate-keepers, reporter molecules or targeting ligands, up to their in-vitro applications in the nanomedicine field.

Biomedical Applications of Inorganic Materials

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Publisher : Royal Society of Chemistry
ISBN 13 : 1788016068
Total Pages : 392 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Biomedical Applications of Inorganic Materials by : Dr Gareth R Williams

Download or read book Biomedical Applications of Inorganic Materials written by Dr Gareth R Williams and published by Royal Society of Chemistry. This book was released on 2021-12-20 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a contemporary research-led overview of the applications of inorganic materials in biomedicine. It begins with a short introduction summarising key concepts in inorganic materials (layered materials, framework materials etc.), and explaining the need for new materials in medicine. It then discusses the key areas in which inorganic materials have been applied, considering: drug delivery; imaging; diagnostics and theranostics; hard matter restoration; and vaccines. Each chapter gives an overview of the major extant challenges in the research area, before presenting a systematic review of how inorganic materials have been applied to gain traction in the field. A clear focus is maintained on the fate of the applied materials in vivo, clinical considerations, and the path to translation from lab to clinic. With contributions from leading researchers, Biomedical Applications of Inorganic Materials will provide a comprehensive introduction for advanced undergraduates, postgraduates and researchers wishing to learn about the topic.

Nanocarriers for Drug Delivery

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Publisher : Springer Nature
ISBN 13 : 3030633896
Total Pages : 347 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Nanocarriers for Drug Delivery by : Josimar O. Eloy

Download or read book Nanocarriers for Drug Delivery written by Josimar O. Eloy and published by Springer Nature. This book was released on 2021 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers basic aspects of different nanoparticles, including type of materials, lipid, polymeric and inorganic structures, synthesis strategies, as well as the main physicochemical characterization techniques. Moreover, this book addresses applications for both treatment and diagnosis of diseases, highlighting in vitro and in vivo findings and clinical evaluation. The chapters highlight the main barriers for drug delivery which can benefit from nanoencapsulation: the topical and oral routes. The main innovations in the field, such as gene therapy and functionalization of nanoparticles with a variety of moieties, including monoclonal antibodies for selective delivery, are discussed and illustrated with examples. Finally, the application of nanoparticles for drug delivery to cancer is reviewed considering toxicology and regulatory aspects.

Inorganic Frameworks as Smart Nanomedicines

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Publisher : William Andrew
ISBN 13 : 0128136626
Total Pages : 727 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Inorganic Frameworks as Smart Nanomedicines by : Alexandru Mihai Grumezescu

Download or read book Inorganic Frameworks as Smart Nanomedicines written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2018-04-09 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inorganic Frameworks as Smart Nanocarriers for Drug Delivery brings together recent research in the area of inorganic frameworks for drug delivery. Different types of nanocarriers are presented and discussed in detail, providing an up-to-date overview on inorganic nanoparticles with pharmaceutical applications. Written by a diverse range of international academics, this book is a valuable reference resource for researchers in biomaterials, the pharmaceutical industry, and those who want to learn more about the current applications of inorganic smart nanocarriers. Includes assembly methods for a variety of smart nanocarrier systems, also showing how they are applied Highlights how metal-oxide nanoparticles are effectively used in drug delivery Assesses the pros and cons of different metallic nanomaterials as drug carriers

Nanoparticles for Drug Delivery

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Publisher : Springer Nature
ISBN 13 : 9811621195
Total Pages : 214 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Nanoparticles for Drug Delivery by : K. S. Joshy

Download or read book Nanoparticles for Drug Delivery written by K. S. Joshy and published by Springer Nature. This book was released on 2021-06-21 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the reader to drug delivery with specific emphasis on the use of nanoparticles. It covers properties, characterization, and preparation of different types of nanoparticles and discusses recent advances in their structural design and biomedical application, as well as the issues and challenges associated with their design and use. Some of the topics covered include the potential application of nanoparticles in biomedical fields, hazards associated with use of nanoparticles for drug delivery, size-dependent factors in drug delivery applications, different organic, inorganic and their hybrid systems used in drug delivery, etc. It also highlights use of nanoparticles in controlled and targeted drug delivery, and their application in stimuli-responsive, especially pH-responsive, drug release. Additionally, it also focuses on biomimetic nanoparticles, challenges faced in the designing of nanoparticles for drug delivery in cancer, viral and bacterial diseases. The contents of this volume will be useful to researchers and professionals working on advances in targeted drug delivery systems.

Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering

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Publisher : John Wiley & Sons
ISBN 13 : 1118644743
Total Pages : 633 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering by : Ashutosh Tiwari

Download or read book Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering written by Ashutosh Tiwari and published by John Wiley & Sons. This book was released on 2013-02-19 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume provides the reader valuable insight into the major areas of biomedical nanomaterials, advanced nanomedicine, nanotheragnostics, and cutting-edge nanoscaffolds. The ability to control the structure of materials allows scientists to accomplish what once appeared impossible before the advent of nanotechnology. It is now possible to generate nanoscopic self-assembled and self-destructive robots for effective utilization in therapeutics, diagnostics, and biomedical implants. Nanoscopic therapeutic systems incorporate therapeutic agents, molecular targeting, and diagnostic imaging capabilities and they have emerged as the next generation of multifarious nanomedicine to improve the therapeutic outcome including chemo and translational therapy. Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering comprises fifteen chapters authored by senior scientists, and is one of the first books to cover nanotheragnostics, which is the new developmental edge of nanomedicine combining both diagnostic and therapeutic elements at the nano level. This large multidisciplinary reference work has four main parts: biomedical nanomaterials; advanced nanomedicine; nanotheragnostics; and nanoscaffolds technology. This groundbreaking volume also covers: Multifunctional polymeric nanostructures for therapy and diagnosis Metalla-assemblies acting as drug carriers Nanomaterials for management of lung disorders and drug delivery Responsive polymer-inorganic hybrid nanogels for optical sensing, imaging, and drug delivery Core/shell nanoparticles for drug delivery and diagnosis Theranostic nanoparticles for cancer imaging and therapy Magnetic nanoparticles in tissue regeneration Core-sheath fibers for regenerative medicine

Inorganic Nanosystems

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Publisher : Academic Press
ISBN 13 : 0323885780
Total Pages : 661 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Inorganic Nanosystems by : Md Saquib Hasnain

Download or read book Inorganic Nanosystems written by Md Saquib Hasnain and published by Academic Press. This book was released on 2023-03-23 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inorganic Nanosystems: Theranostic Nanosystems, Volume Two examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials. It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications. Contains in-depth discussions of the inorganic nanosystems including high-quality graphics, flowcharts, and graphs for enhanced understanding Reviews the literature on inorganic nanosystems while also suggesting new avenues Includes contributions in all areas of inorganic nanosystems, providing a thorough and interdisciplinary work

Molecular Machines Supported on Mesoporous Silica Nanoparticles for Drug Delivery Applications

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Publisher :
ISBN 13 :
Total Pages : 236 pages
Book Rating : 4.:/5 (427 download)

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Book Synopsis Molecular Machines Supported on Mesoporous Silica Nanoparticles for Drug Delivery Applications by : Sarah Ann Angelos

Download or read book Molecular Machines Supported on Mesoporous Silica Nanoparticles for Drug Delivery Applications written by Sarah Ann Angelos and published by . This book was released on 2009 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multifunctional Nanoparticles for Drug Delivery Applications

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Publisher : Springer Science & Business Media
ISBN 13 : 146142304X
Total Pages : 371 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Multifunctional Nanoparticles for Drug Delivery Applications by : Sonke Svenson

Download or read book Multifunctional Nanoparticles for Drug Delivery Applications written by Sonke Svenson and published by Springer Science & Business Media. This book was released on 2012-02-22 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles.

Nanomaterials: Evolution and Advancement towards Therapeutic Drug Delivery (Part II)

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Publisher : Bentham Science Publishers
ISBN 13 : 168108824X
Total Pages : 321 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Nanomaterials: Evolution and Advancement towards Therapeutic Drug Delivery (Part II) by : Surendra Nimesh

Download or read book Nanomaterials: Evolution and Advancement towards Therapeutic Drug Delivery (Part II) written by Surendra Nimesh and published by Bentham Science Publishers. This book was released on 2021-06-02 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of a vector for the delivery of therapeutic drugs in a controlled and targeted fashion is still a major challenge in the treatment of many diseases. The conventional application of drugs may lead to many limitations including poor distribution, limited effectiveness, lack of selectivity and dose dependent toxicity. An efficient drug delivery system can address these problems. Recent nanotechnology advancements in the biomedical field have the potential to meet these challenges in developing drug delivery systems. Nanomaterials are changing the biomedical platform in terms of disease diagnosis, treatment and prevention. Nanomaterials aided drug delivery provides an advantage by enhancing aqueous solubility that leads to improved bioavailability, increased resistance time in the body, decreased side effects by targeting drugs to the specific location, reduced dose dependent toxicity and protection of drugs from early release. In this two-part book, the contributors have compiled reports of recent studies illustrating the promising nanomaterials that can work as drug carriers which can navigate conventional physiological barriers. A detailed account of several types of nanomaterials including polymeric nanoparticles, liposomes, dendrimers, micelles, carbon nanomaterials, magnetic nanoparticles, solid lipid-based nanoparticles, silica nanomaterials and hydrogels for drug delivery is provided in separate chapters. The contributors also present a discussion on clinical aspects of ongoing research with insights towards future prospects of specific nanotechnologies. Part II covers the following topics: · Solid lipid nanoparticles and nanostructured lipid carriers · Silica based nanomaterials · Hydrogels · Metallic nanoparticles · Computational and experimental binding interactions of drug and β-cyclodextrin · Clinical milestones in nanotherapeutics · Drug delivery systems based on poly(lactide-co-glycolide) and its copolymers The book set is an informative resource for scholars who seek updates in nanomedicine with reference to nanomaterials used in drug delivery systems.

Nanoparticulate Drug Delivery Systems

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Publisher : CRC Press
ISBN 13 : 1351137247
Total Pages : 423 pages
Book Rating : 4.3/5 (511 download)

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Book Synopsis Nanoparticulate Drug Delivery Systems by : Raj K. Keservani

Download or read book Nanoparticulate Drug Delivery Systems written by Raj K. Keservani and published by CRC Press. This book was released on 2019-01-23 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on nanoparticulate nanocarriers and recent advances in the field of drug delivery, the volume begins with chapters that provide an informative introduction to polymeric nanoparticles—their general physicochemical features and characteristics, their applications in drug delivery systems, and the challenges involved. Specific applications are discussed, with attention paid to treatment of particular diseases and disorders and the targeting of specific organs. Part 2 looks at more specific applications and techniques of nanoparticulate nanocarriers for drug delivery, such as the use of magnetic nanoparticles, gold nanoparticles in therapeutics, and superparamagnetic iron oxide nanoparticles (SPIONs) for the treatment of cancer. Part 3 discusses lipid-based nanoparticulates for various applications, including skin care. The last section of the book explores some of the newer nanoarchitectures, including dendrimers in gene delivery and carbon nanotubes for drug delivery. Together, the insightful research presented here provides valuable information for those involved in this area, including scientists and researchers and faculty and upper-level students, as well as for industry professionals.

Nanomedicine for Drug Delivery and Therapeutics

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Publisher : John Wiley & Sons
ISBN 13 : 1118635841
Total Pages : 372 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Nanomedicine for Drug Delivery and Therapeutics by : Ajay Kumar Mishra

Download or read book Nanomedicine for Drug Delivery and Therapeutics written by Ajay Kumar Mishra and published by John Wiley & Sons. This book was released on 2013-02-01 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes a broad area of nanomedicine which involves mainly applications, diseases, and diagnostics. The comprehensive coverage provides researchers, academics, and health specialists with a great tool, that includes techniques applicable to various uses.

Biomedical Applications of Mesoporous Ceramics

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Publisher : CRC Press
ISBN 13 : 1439883084
Total Pages : 233 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Biomedical Applications of Mesoporous Ceramics by : María Vallet-Regí

Download or read book Biomedical Applications of Mesoporous Ceramics written by María Vallet-Regí and published by CRC Press. This book was released on 2012-11-28 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developments in mesoporous ceramics in drug delivery, nanomedicine, and bone tissue regeneration have opened promising developments in biomedical research, many applicable in the clinic in the near future. Due to the ability to fine-tune the physicochemical properties of these materials, the field has experienced an impressive burst in the number o

Drug Delivery Using Nanomaterials

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Publisher : CRC Press
ISBN 13 : 1000529495
Total Pages : 360 pages
Book Rating : 4.0/5 (5 download)

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Book Synopsis Drug Delivery Using Nanomaterials by : Yasser Shahzad

Download or read book Drug Delivery Using Nanomaterials written by Yasser Shahzad and published by CRC Press. This book was released on 2022-01-18 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: After the drug discovery and development process, designing suitable formulations to safely deliver the optimum dose, while avoiding side effects, has been a constant challenge, especially when drugs are very toxic and have poor solubility and undesirable clearance profiles. With recent advances in synthetic technologies, nanoparticles can be custom-made from a variety of advanced materials to mimic the bioenvironment and can be equipped with various targeting and imaging moieties for site-specific delivery and real-time imaging. Drug Delivery Using Nanomaterials covers advancements in the field of nanoparticle-based drug-delivery systems, along with all the aspects needed for a successful and marketable nanoformulation. FEATURES Offers a general overview of the entire process involved in the synthesis and characterization of pharmaceutical nanoparticles Covers a broad range of synthetic materials for developing nanoformulations customized for specific disease states, target organs, and drugs Every chapter sequentially builds, providing a progressive pathway from classical nanoparticles to the more advanced to be used as a full drug product by consumers Provides information in a bottom-up manner in that definitions and explanations of relevant background information serve as a framework for understanding advanced concepts This user-friendly reference is aimed at materials engineers, chemical engineers, biomedical engineers, pharmaceutical scientists, chemists, and others working on advanced drug delivery, from academia as well as industry.

Nanoscience in Dermatology

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Publisher : Academic Press
ISBN 13 : 0128029455
Total Pages : 404 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Nanoscience in Dermatology by : Michael R. Hamblin

Download or read book Nanoscience in Dermatology written by Michael R. Hamblin and published by Academic Press. This book was released on 2016-08-13 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoscience in Dermatology covers one of the two fastest growing areas within dermatological science, nanoscience and nanotechnology in dermatology. Recently, great progress has been made in the research and development of nanotechnologies and nanomaterials related to various applications in medicine and, in general, the life sciences. There is increasing enthusiasm for nanotechnology applications in dermatology (drug delivery, diagnostics, therapeutics, imaging, sensors, etc.) for understanding skin biology, improving early detection and treatment of skin diseases, and in the design and optimization of cosmetics. Light sensitive nanoparticles have recently been explored, opening a new era for the combined applications of light with nanotechnology, also called photonanodermatology. However, concerns have been raised regarding the adverse effects of intentional and unintentional nanoparticle exposure and their toxicity. Written by experts working in these exciting fields, this book extensively covers nanotechnology applications, together with the fundamentals and toxicity aspects. It not only addresses current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing scientists and dermatologists with a clear understanding of the advantages and challenges of nanotechnology in skin medicine. Provides knowledge of current and future applications of nanoscience and nanotechnology in dermatology Outlines the fundamentals, methods, toxicity aspects, and other relevant aspects for nanotechnology based applications in dermatology Coherently structured book written by experts working in the fields covered