Mechanisms Of Longevity Extension By Caloric Restriction And Lithocholic Acid In The Yeast Saccharomyces Cerevisiae

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Aging and Age-Related Disorders From Molecular Mechanisms to Therapies

Author : Vladimir Titorenko
Publisher : MDPI
ISBN 13 : 3039213555
Total Pages : 322 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Aging and Age-Related Disorders From Molecular Mechanisms to Therapies by : Vladimir Titorenko

Download or read book Aging and Age-Related Disorders From Molecular Mechanisms to Therapies written by Vladimir Titorenko and published by MDPI. This book was released on 2019-08-19 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging of unicellular and multicellular eukaryotic organisms is a convoluted biological phenomenon, which is manifested as an age-related functional decline caused by progressive dysregulation of certain cellular and organismal processes. Many chronic diseases are associated with human aging. These aging-associated diseases include cardiovascular diseases, chronic obstructive pulmonary disease, chronic kidney disease, diabetes, osteoarthritis, osteoporosis, sarcopenia, stroke, neurodegenerative diseases (including Parkinson’s, Alzheimer’s, and Huntington’s diseases), and many forms of cancer. Studies in yeast, roundworms, fruit flies, fishes, mice, primates, and humans have provided evidence that the major aspects and basic mechanisms of aging and aging-associated pathology are conserved across phyla. The focus of this International Journal of Molecular Sciences Special Issue is on molecular and cellular mechanisms, diagnostics, and therapies and diseases of aging. Fifteen original research and review articles in this Special Issue provide important insights into how various genetic, dietary, and pharmacological interventions can affect certain longevity-defining cellular and organismal processes to delay aging and postpone the onset of age-related pathologies in evolutionarily diverse organisms. These articles outline the most important unanswered questions and directions for future research in the vibrant and rapidly evolving fields of mechanisms of biological aging, aging-associated diseases, and aging-delaying therapies.

Stem Cell Aging: Mechanisms, Consequences, Rejuvenation

Author : Hartmut Geiger
Publisher : Springer
ISBN 13 : 370911232X
Total Pages : 357 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Stem Cell Aging: Mechanisms, Consequences, Rejuvenation by : Hartmut Geiger

Download or read book Stem Cell Aging: Mechanisms, Consequences, Rejuvenation written by Hartmut Geiger and published by Springer. This book was released on 2015-07-06 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging of somatic stem cells reduces cell function and results in dysfunctional organs and tissues, making it an underlying cause of diseases associated with aging. It might even be the primary cause for age-associated attrition of tissue function in organs that heavily rely on stem cells for maintaining homeostasis, like the skin, blood and intestines. Understanding the molecular and cellular mechanisms involved is critical for developing approaches to attenuate stem cell aging and could pave the way for improved quality of life among the elderly. Written by highly prominent experts in the field, this book presents the current state of knowledge on these mechanisms. It offers insights into stem cell function, explains in detail the mechanisms of stem cell aging in model organisms as well as mammalian systems and describes related diseases and approaches to attenuating stem cell aging or achieving rejuvenation. The book is intended for all scientists and clinicians working with stem cells, aging mechanisms or age-related diseases.

The Retardation of Aging and Disease by Dietary Restriction

Author : Richard Weindruch
Publisher : Charles C Thomas Pub Limited
ISBN 13 : 9780398054960
Total Pages : 436 pages
Book Rating : 4.0/5 (549 download)

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Book Synopsis The Retardation of Aging and Disease by Dietary Restriction by : Richard Weindruch

Download or read book The Retardation of Aging and Disease by Dietary Restriction written by Richard Weindruch and published by Charles C Thomas Pub Limited. This book was released on 1988-01-01 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Food Bioactives

Author : Munish Puri
Publisher : Springer
ISBN 13 : 3319516396
Total Pages : 329 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Food Bioactives by : Munish Puri

Download or read book Food Bioactives written by Munish Puri and published by Springer. This book was released on 2017-04-07 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on various types of bioactive compounds, including secondary metabolites, oligosaccharides, polysaccharides, flavonoids, peptides/proteins, carotenoid pigments, quinones, terpenes, and polyunsaturated fatty acids, and presents an overview of their nutraceutical activities. It covers the current status and future potential of food compounds, as well as extraction technologies for bioactives derived from plant, fungi and marine-derived bioactive agents. Finally, health-promoting effects of plant, fungi and marine-derived bioactive agents are discussed. Chapters come from top researchers in this area from around the globe. The volume caters to the needs of undergraduate and post-graduate students in the area of food biotechnology, food bioprocessing, biotechnology, food engineering, etc., and also contains information pertinent to researchers.

Methods in Yeast Genetics

Author : David C. Amberg
Publisher : CSHL Press
ISBN 13 : 0879697288
Total Pages : 250 pages
Book Rating : 4.8/5 (796 download)

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Book Synopsis Methods in Yeast Genetics by : David C. Amberg

Download or read book Methods in Yeast Genetics written by David C. Amberg and published by CSHL Press. This book was released on 2005 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Methods in Yeast Genetics" is a course that has been offered annually at Cold Spring Harbor for the last 30 years. This provides a set of teaching experiments along with the protocols and recipes for the standard techniques and reagents used in the study of yeast biology.

Molecular Wine Microbiology

Author : Alfonso V. Carrascosa Santiago
Publisher : Academic Press
ISBN 13 : 0080962580
Total Pages : 373 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Molecular Wine Microbiology by : Alfonso V. Carrascosa Santiago

Download or read book Molecular Wine Microbiology written by Alfonso V. Carrascosa Santiago and published by Academic Press. This book was released on 2011-05-23 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Wine Microbiology features rigorous scientific content written at a level comprehensible for wine professionals as well as advanced students. It includes information on production and spoilage issues, the microbial groups relevant for wine production and microbial wine safety. Microbiology has long been recognized as a key tool in studying wine production, however only recently have wine microbiology studies been addressed at a molecular level, increasing the understanding of how microbiology impacts not only the flavor quality of the wine, but also its safety. Understanding, at a molecular level, how a starter culture can impact ethanol, glycerol, volatile phenols, mannoproteins, biogenic amines or ochratoxin A of a wine are just some of the core points that must be considered in order to achieve maximium consumer acceptability while addressing safety concerns during processing and storage. While other books offer insights into the technological aspects of enology, this book is written by expert microbiologists, who explore the positive and negative impacts of gene function in the production of wine, from a microbiological point of view. - Winner of the 2012 Jury Award in Enology from the International Organisation of Vine and Wine - Presents the most current methods of studying the microbiology of wine - Includes latest identification and typing methods, reducing identification time from days and weeks to minutes and hours - Provides important knowledge about the impact of microbiological factors at the molecular level for reduction of wine spoilage and increased wine quality and safety

Dorland's Dictionary of Medical Acronyms and Abbreviations

Author : Dorland
Publisher : Elsevier Health Sciences
ISBN 13 : 0323442544
Total Pages : 481 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Dorland's Dictionary of Medical Acronyms and Abbreviations by : Dorland

Download or read book Dorland's Dictionary of Medical Acronyms and Abbreviations written by Dorland and published by Elsevier Health Sciences. This book was released on 2015-07-24 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical acronyms and abbreviations offer convenience, but those countless shortcuts can often be confusing. Now a part of the popular Dorland's suite of products, this reference features thousands of terms from across various medical specialties. Its alphabetical arrangement makes for quick reference, and expanded coverage of symbols ensures they are easier to find. Effective communication plays an important role in all medical settings, so turn to this trusted volume for nearly any medical abbreviation you might encounter. - Symbols section makes it easier to locate unusual or seldom-used symbols. - Convenient alphabetical format allows you to find the entry you need more intuitively. - More than 90,000 entries and definitions. - Many new and updated entries including terminology in expanding specialties, such as Nursing; Physical, Occupational, and Speech Therapies; Transcription and Coding; Computer and Technical Fields. - New section on abbreviations to avoid, including Joint Commission abbreviations that are not to be used. - Incorporates updates suggested by the Institute for Safe Medication Practices (ISMP).

Science and Technology of Fibers in Food Systems

Author : Jorge Welti-Chanes
Publisher : Springer Nature
ISBN 13 : 3030386546
Total Pages : 464 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Science and Technology of Fibers in Food Systems by : Jorge Welti-Chanes

Download or read book Science and Technology of Fibers in Food Systems written by Jorge Welti-Chanes and published by Springer Nature. This book was released on 2020-04-15 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides comprehensive coverage of fibers used in food formulations, starting with the understanding of their basic chemical structure and how they are present and organized in the cell wall structure, their physicochemical and functional properties, their impact on the digestive process and their role and preventive action against various chronic diseases including colon cancer. The book focuses on traditional and new fiber rich sources, incorporating an integrated approach in terms of the technological and engineering processes used to obtain and incorporate them in traditional foods, plus their characterization, extraction and modification. The study of processing conditions including the chemical, physical and enzymatic processes of fiber extraction and modification are also covered, including traditional and emerging processing technologies, plus the application of fibers in the development of new products and processes. Science and Technology of Fibers in Food Systems integrates knowledge of fibers from their basic structural and property aspects and the applications of these ingredients to extraction process analysis, modification and feasibility for use at the industry level. The chapters incorporate the physiological aspects related to the consumption of fiber for prevention of serious diseases.

Principles of Animal Nutrition

Author : Guoyao Wu
Publisher : CRC Press
ISBN 13 : 1351646370
Total Pages : 1092 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Principles of Animal Nutrition by : Guoyao Wu

Download or read book Principles of Animal Nutrition written by Guoyao Wu and published by CRC Press. This book was released on 2017-11-22 with total page 1092 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animals are biological transformers of dietary matter and energy to produce high-quality foods and wools for human consumption and use. Mammals, birds, fish, and shrimp require nutrients to survive, grow, develop, and reproduce. As an interesting, dynamic, and challenging discipline in biological sciences, animal nutrition spans an immense range from chemistry, biochemistry, anatomy and physiology to reproduction, immunology, pathology, and cell biology. Thus, nutrition is a foundational subject in livestock, poultry and fish production, as well as the rearing and health of companion animals. This book entitled Principles of Animal Nutrition consists of 13 chapters. Recent advances in biochemistry, physiology and anatomy provide the foundation to understand how nutrients are utilized by ruminants and non-ruminants. The text begins with an overview of the physiological and biochemical bases of animal nutrition, followed by a detailed description of chemical properties of carbohydrates, lipids, protein, and amino acids. It advances to the coverage of the digestion, absorption, transport, and metabolism of macronutrients, energy, vitamins, and minerals in animals. To integrate the basic knowledge of nutrition with practical animal feeding, the book continues with discussion on nutritional requirements of animals for maintenance and production, as well as the regulation of food intake by animals. Finally, the book closes with feed additives, including those used to enhance animal growth and survival, improve feed efficiency for protein production, and replace feed antibiotics. While the classical and modern concepts of animal nutrition are emphasized throughout the book, every effort has been made to include the most recent progress in this ever-expanding field, so that readers in various biological disciplines can integrate biochemistry and physiology with nutrition, health, and disease in mammals, birds, and other animal species (e.g., fish and shrimp). All chapters clearly provide the essential literature related to the principles of animal nutrition, which should be useful for academic researchers, practitioners, beginners, and government policy makers. This book is an excellent reference for professionals and a comprehensive textbook for senior undergraduate and graduate students in animal science, biochemistry, biomedicine, biology, food science, nutrition, veterinary medicine, and related fields.

Oxidative Stress and Age-Related Neurodegeneration

Author : Yuan Luo
Publisher : CRC Press
ISBN 13 : 1420026550
Total Pages : 524 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Oxidative Stress and Age-Related Neurodegeneration by : Yuan Luo

Download or read book Oxidative Stress and Age-Related Neurodegeneration written by Yuan Luo and published by CRC Press. This book was released on 2005-11-21 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative Stress and Age-Related Neurodegeneration brings together researchers from a variety of fields to compare normal aging and disease-related neurodegeneration in terms of susceptibility to and effects of oxidative stress. They address how these effects can be attenuated, and examine whether antioxidants and natural micronutrients, such as those found in Gingko biloba, green tea, blueberries, and grape seed extract, can play a role. The book includes various ways research is getting to the core of neurodegenerative disease, including the use of proteomics, comparisons to related diseases, and examinations at the cellular and molecular levels.

Origin and spatiotemporal dynamics of the peroxisomal endomembrane system

Author : Vladimir I Titorenko
Publisher : Frontiers Media SA
ISBN 13 : 2889194647
Total Pages : 149 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Origin and spatiotemporal dynamics of the peroxisomal endomembrane system by : Vladimir I Titorenko

Download or read book Origin and spatiotemporal dynamics of the peroxisomal endomembrane system written by Vladimir I Titorenko and published by Frontiers Media SA. This book was released on 2015-03-05 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: The peroxisome is an organelle with essential roles in lipid metabolism, maintenance of reactive oxygen species homeostasis, and anaplerotic replenishment of tricarboxylic acid cycle intermediates destined for mitochondria. Peroxisomes constitute a dynamic endomembrane system. The homeostatic state of this system is upheld via two pathways for assembling and maintaining the diverse peroxisomal compartments constituting it; the relative contribution of each pathway to preserving such system may vary in different organisms and under various physiological conditions. One pathway begins with the targeting of certain peroxisomal membrane proteins to an endoplasmic reticulum template and their exit from the template via pre-peroxisomal carriers; these carriers mature into metabolically active peroxisomes containing the entire complement of membrane and matrix proteins. Another pathway operates via growth and maturation of pre-existing peroxisomal precursors that do not originate from the endoplasmic reticulum; mature peroxisomes proliferate by undergoing fission. Recent studies have uncovered new roles for the peroxisomal endomembrane system in orchestrating important developmental decisions and defining organismal longevity. This Frontiers Special Topic Issue is focused on the advances in our understanding of how evolutionarily distant organisms coordinate the formation, maturation, proliferation, maintenance, inheritance and quality control of the peroxisomal endomembrane system and how peroxisomal endomembranes communicate with other cellular compartments to orchestrate complex biological processes and various developmental programs from inside the cell.

Encyclopedia of Molecular Pharmacology

Author : Stefan Offermanns
Publisher : Springer Science & Business Media
ISBN 13 : 3540389164
Total Pages : 1515 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Encyclopedia of Molecular Pharmacology by : Stefan Offermanns

Download or read book Encyclopedia of Molecular Pharmacology written by Stefan Offermanns and published by Springer Science & Business Media. This book was released on 2008-08-14 with total page 1515 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.

Conn's Handbook of Models for Human Aging

Author : Jeffrey L. Ram
Publisher : Academic Press
ISBN 13 : 0128113545
Total Pages : 1220 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Conn's Handbook of Models for Human Aging by : Jeffrey L. Ram

Download or read book Conn's Handbook of Models for Human Aging written by Jeffrey L. Ram and published by Academic Press. This book was released on 2018-04-05 with total page 1220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approach, this updated edition is designed as the only comprehensive, current work that covers the diversity in aging models. Chapters on comparative models explore age-related diseases, including Alzheimer's, joint disease, cataracts, cancer and obesity. Also included are new tricks and approaches not available in primary publications. This must-have handbook is an indispensable resource for researchers interested in the mechanisms of aging, gerontologists, health professionals, allied health practitioners and students. - Combines both the methods of study for human aging and animal models - Provides a historical overview and discussion of model availability, key methods and ethical issues - Contains over 200 full color illustrations

Theranostics Approaches to Gastric and Colon Cancer

Author :
Publisher :
ISBN 13 : 9789811520181
Total Pages : 261 pages
Book Rating : 4.5/5 (21 download)

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Book Synopsis Theranostics Approaches to Gastric and Colon Cancer by :

Download or read book Theranostics Approaches to Gastric and Colon Cancer written by and published by . This book was released on 2020 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the importance of understanding gastric and colon cancer metabolism in guiding diagnosis and drug discovery. It summarizes the correlation between adiponectin and matrix metalloproteinase with colorectal cancer. The book also evaluates the divergent role of hypoxia-inducible factor 1 in colorectal cancer growth and metastasis. After discussing the role of genetic polymorphisms in alcohol metabolizing enzymes and EPHX1 with the onset of colorectal cancer, it reviews the molecular mechanisms of chemoresistance in gastric cancer and novel therapeutic strategies to reverse the chemoresistance of tumors. In addition, the book explores the theranostic role of nanoparticles and therapeutic potential of phytochemicals with regard to colorectal cancer. Given its scope, the book offers a valuable guide for oncologists, academic researchers, pharmaceuticals practitioners, and students who are involved in research and treatment of cancer. --

Atlas of Drosophila Morphology

Author : Sylwester Chyb
Publisher : Academic Press
ISBN 13 : 0123846897
Total Pages : 243 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Atlas of Drosophila Morphology by : Sylwester Chyb

Download or read book Atlas of Drosophila Morphology written by Sylwester Chyb and published by Academic Press. This book was released on 2013-03-23 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Atlas of Drosophila Morphology: Wild-type and Classical Mutants is the guide every Drosophila researcher wished they had when first learning genetic markers, and the tool they wish they had now as a handy reference in their lab research. Previously, scientists had only poor-quality images or sketches to work with, and then scattered resources online - but no single visual resource quickly at their fingertips when explaining markers to new members of the lab, or selecting flies to do their genetic crosses, or hybrids. This alphabetized guide to Drosophila genetic markers lays flat in the lab for easy referencing. It contains high-resolution images of flies and the appropriate marker on the left side of each page and helpful information for the marker on the facing page, such as symbol, gene name, synonyms, chromosome location, brief informative description of the morphology, and comments on marker reliability. A companion website with updated information, useful links, and additional data provided by the authors complements this extremely valuable resource. - Provides an opening chapter with a well-illustrated introduction to Drosophila morphology - Features high-resolution illustrations, including those of the most common markers used by Drosophila researchers - Contains brief, practical descriptions and tips for deciphering the phenotype - Includes material relevant for beginners and the most experienced fly pushers

Handbook of Prebiotics

Author : Glenn R. Gibson
Publisher : CRC Press
ISBN 13 : 0849381827
Total Pages : 506 pages
Book Rating : 4.8/5 (493 download)

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Book Synopsis Handbook of Prebiotics by : Glenn R. Gibson

Download or read book Handbook of Prebiotics written by Glenn R. Gibson and published by CRC Press. This book was released on 2008-01-29 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to achieve optimal digestion, absorption, and nutritional health, we must have appropriate populations of positive microflora. Prebiotics are functional foods that improve health by fortifying indigenous probiotics within the gut. This fast-growing area of nutrition and microbiology is rapidly amassing data and answering many questions abo

Clinical Metabolomics

Author : Martin Giera
Publisher :
ISBN 13 : 9781493975921
Total Pages : 389 pages
Book Rating : 4.9/5 (759 download)

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Book Synopsis Clinical Metabolomics by : Martin Giera

Download or read book Clinical Metabolomics written by Martin Giera and published by . This book was released on 2018 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume presents a comprehensive compendium of clinical metabolomics protocols covering LC-MS, GC-MS, CE-MS, and NMR-based clinical metabolomics as well as bioinformatics and study design considerations. The methodologies explored here form the core of several very promising initiatives evolving around personalized health care and precision medicine, which can be seen as complimentary to the field of clinical chemistry and aid the aforementioned field with novel disease markers and diagnostic patterns. Written for the highly successful Methods in Molecular Biology series, chapters include brief introductions to their topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.uthoritative and practical, Clinical Metabolomics: Methods and Protocols aims to serve as the basis for successful communication between scientists from several fields, including chemists, biologist, bioinformaticians, and clinicians, ultimately leading to effective study design and completion.