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Author :
Publisher :
ISBN 13 :
Total Pages : 154 pages
Book Rating : 4.:/5 (45 download)
Download or read book Mechanisms of Environmental Carcinogenesis: Multistep models of carcinogenesis written by and published by . This book was released on 1987 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J. Carl Barrett
Publisher : CRC-Press
ISBN 13 : 9780849346729
Total Pages : 144 pages
Book Rating : 4.3/5 (467 download)
Download or read book MECHANISM OF ENVIRONMENTAL CARCINOGENESIS written by J. Carl Barrett and published by CRC-Press. This book was released on 1987-07-31 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Elizabeth K. Weisburger
Publisher : Springer Science & Business Media
ISBN 13 : 9400925263
Total Pages : 210 pages
Book Rating : 4.4/5 (9 download)
Download or read book Mechanisms of Carcinogenesis written by Elizabeth K. Weisburger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.
Author : J. Carl Barrett
Publisher : CRC-Press
ISBN 13 : 9780849346712
Total Pages : 0 pages
Book Rating : 4.3/5 (467 download)
Download or read book MECHANISM OF ENVIRONMENTAL CARCINOGENIS written by J. Carl Barrett and published by CRC-Press. This book was released on 1987-07-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author : A. Kappas
Publisher : Springer Science & Business Media
ISBN 13 : 1461538084
Total Pages : 276 pages
Book Rating : 4.4/5 (615 download)
Download or read book Mechanisms of Environmental Mutagenesis-Carcinogenesis written by A. Kappas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 19th annual meeting of the European Environmental Mutagen Society was held in Rhodes, Greece, from October 21st to 26th, 1989. The programme was chosen to explore what is currently known about the mechanisms of mutagenesis and carcinogenesis, induced by environmental agents, and the questions regarding the relationship of these two processes. Recent findings, techniques and methodologies in the area of biomonitoring of humans exposed to environmental mutagens-carcinogens were presented and considerable attention was also paid to the aspects and issues of collaborative environmental policy. Researchers from allover the world contributed to the programme of the meeting with posters and oral presentations, providing a variety of new data and interesting scientific approaches. A number of outstanding scientists were invited to present the results of their work. It is only their presenta tions which are included in this book, covering the following topics: Mutations and carcinogenesis; mechanisms of chemical ly-induced genetic effects on molecular, chromosomal and cell division level; adaptability and repair mechanisms; chemical carcinogenesis and oncogenes; structure and metabolism of mutagens-carcinogens; biomonitoring and epidemiology of humans exposed to environmental mutagens-carcinogens. For the sake of evaluating and controlling the mutagenic and carcinogenic potential of our environment it is indispens able to understand the mechanisms and processes by which chemicals act on the genetic material, causing either heredi tary disease or cancer. The pUblication of these proceedings will hopefully contribute to this task.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309053919
Total Pages : 434 pages
Book Rating : 4.3/5 (9 download)
Download or read book Carcinogens and Anticarcinogens in the Human Diet written by National Research Council and published by National Academies Press. This book was released on 1996-03-12 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.
Author : Trevor M. Penning
Publisher : Springer Science & Business Media
ISBN 13 : 1617379956
Total Pages : 447 pages
Book Rating : 4.6/5 (173 download)
Download or read book Chemical Carcinogenesis written by Trevor M. Penning and published by Springer Science & Business Media. This book was released on 2011-03-03 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many cancers. The multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action will be a focal point. The balance between metabolic activation to form biological reactive intermediates and their detoxification, ensuing DNA-lesions and their repair will be profiled. It will describe the chemical changes that occur in DNA that result from endogenous insults including epigenetic changes that lead to gene silencing. It will describe major mechanisms of mutagenesis, affects on tumor suppressor genes and proto-oncogenes, and how cell-cycle check points can be by-passed by the "stealth-like" properties of chemical carcinogens. Environmental agents that can promote tumor formation will be discussed. The monograph will have wide appeal as a knowledge base for graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research.
Author : Alecsandru Ioan Baba
Publisher :
ISBN 13 : 9789732714577
Total Pages : 787 pages
Book Rating : 4.7/5 (145 download)
Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Elsevier
ISBN 13 : 0323997767
Total Pages : 382 pages
Book Rating : 4.3/5 (239 download)
Download or read book Environmental Carcinogenesis written by and published by Elsevier. This book was released on 2023-02-28 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Carcinogenesis, Volume 96 in the Advances in Pharmacology series, reports on work done with carcinogenic metals and the mechanisms of their carcinogenicity, including Arsenic and Chromate. Chapters in this release include Breast cancer carcinogenesis by organophosphate pesticides, Polyadenylation of Canonical histone H3.1 in Carcinogenesis, Epigenomic reprogramming in iAs-mediated carcinogenesis, MicroRNAs and epigenetic regulation in metal-induced angiogenesis and carcinogenesis, Environmental epigenetics and new mechanistic markers of chemical exposure, Arsenic carcinogenesis by inhibition of DNA repair, Genetic and environmental reprogramming of the sarcoma epigenome, Mechanism of chromate carcinogenesis by chromatin alterations, and more. Other chapters cover Arsenic carcinogenesis and microRNAs, Epigenetic mechanism of Cr(VI)-induced cell malignant transformation and tumorigenesis, The dark side of NRF2 in arsenic carcinogenesis, and Chemical mechanisms of DNA damage by carcinogenic chromium(VI). Covers metal carcinogens Includes discussions on the mechanisms of cancer formation Provides updates on the diverse mechanisms that drive cancer formation by metals
Author : Piet Emmelot
Publisher : North Holland
ISBN 13 :
Total Pages : 424 pages
Book Rating : 4.:/5 (42 download)
Download or read book Environmental Carcinogenesis written by Piet Emmelot and published by North Holland. This book was released on 1979 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J. Carl Barrett
Publisher :
ISBN 13 :
Total Pages : 27 pages
Book Rating : 4.:/5 (834 download)
Download or read book Mechanisms of environmental carcinogenesis written by J. Carl Barrett and published by . This book was released on 1987 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309211964
Total Pages : 204 pages
Book Rating : 4.3/5 (92 download)
Download or read book Review of the Environmental Protection Agency's Draft IRIS Assessment of Formaldehyde written by National Research Council and published by National Academies Press. This book was released on 2011-05-31 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Formaldehyde is ubiquitous in indoor and outdoor air, and everyone is exposed to formaldehyde at some concentration daily. Formaldehyde is used to produce a wide array of products, particularly building materials; it is emitted from many sources, including power plants, cars, gas and wood stoves, and cigarettes; it is a natural product in come foods; and it is naturally present in the human body as a metabolic intermediate. Much research has been conducted on the health effects of exposure to formaldehyde, including effects on the upper airway, where formaldehyde is deposited when inhaled, and effects on tissues distant from the site of initial contact. The U.S. Environmental Protection Agency (EPA) released noncancer and cancer assessments of formaldehyde for its Intergated Risk Information System (IRIS) in 1990 and 1991, respectively. The agency began reassessing formaldehyde in 1998 and released a draft IRIS assessment in June 2010. Given the complexity of the issues and the knowledge that the assessment will be used as the basis of regulatory decisions, EPA asked the National Research Council (NRC) to conduct an independent scientific review of the draft IRIS assessment. In this report, the Committee to Review EPA's Draft IRIS Assessment of Formaldehyde first addresses some general issues associated with the draft IRIS assessment. The committee next focuses on questions concerning specific aspects of the draft assessment, including derivation of the reference concentrations and the cancer unit risk estimates for formaldehyde. The committee closes with recommendations for improving the IRIS assessment of formaldehyde and provides some general comments on the IRIS development process.
Author : A Pullman
Publisher :
ISBN 13 : 9789400991057
Total Pages : 608 pages
Book Rating : 4.9/5 (91 download)
Download or read book Carcinogenesis written by A Pullman and published by . This book was released on 1980-10-31 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Solomon Habtemariam
Publisher : Elsevier
ISBN 13 : 0081022948
Total Pages : 232 pages
Book Rating : 4.0/5 (81 download)
Download or read book The African and Arabian Moringa Species written by Solomon Habtemariam and published by Elsevier. This book was released on 2017-06-09 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The African and Arabian Moringa Species: Chemistry, Bioactivity and Therapeutic Applications reviews the botany, socioeconomic significance and underlying chemistry of these interesting plants. The book begins by addressing the botanical and socioeconomic aspect of M. stenopetala, one of the most widely cultivated species within the genus. Next, it reviews the chemistry of the plant, with a systematic presentation covering the seed oil, various secondary metabolites, and issues relating to quality control. Final sections address the chemistry behind the reported use of the plant for the management of various diseases, highlighting potential antioxidant, antimicrobial, antidiabetic, anticancer properties and more. Other African and Arabian Moringa species, from their botany, to their chemical and pharmacological profiles are also included. Drawing on the author’s latest research and the most current literature in the field, this book is an invaluable guide for researchers in medicinal chemistry, herbal medicine, drug discovery/development, and plant derived natural products within both industry and academic environments. Outlines the botanical description, traditional uses and socioeconomic significance of the African and Arabian Moringa plants Exhaustively discusses the chemistry of these plants to highlight secondary metabolites and methodologies for their isolation, identification and quality control Discusses the future potential of the plants and their chemical components for various disease conditions
Author : E. Kriek
Publisher :
ISBN 13 :
Total Pages : 401 pages
Book Rating : 4.:/5 (641 download)
Download or read book Environmental Carcinogenesis written by E. Kriek and published by . This book was released on 1979 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : JC BARRETT (Ed)
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (985 download)
Download or read book MECHANISMS OF ENVIRONMENTAL CARCINOGENESIS; VOL 1; ROLE OF GENETIC AND EPIGENETIC CHANGE. written by JC BARRETT (Ed) and published by . This book was released on 1987 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
