Matrix Assisted Laser Desorption Ionization Mass Spectrometry

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Photoionization and Photo-Induced Processes in Mass Spectrometry

Author : Ralf Zimmermann
Publisher : John Wiley & Sons
ISBN 13 : 3527335102
Total Pages : 448 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Photoionization and Photo-Induced Processes in Mass Spectrometry by : Ralf Zimmermann

Download or read book Photoionization and Photo-Induced Processes in Mass Spectrometry written by Ralf Zimmermann and published by John Wiley & Sons. This book was released on 2021-07-06 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of laser-induced ionization processes for mass spectrometry analysis Drawing on the expertise of the leading academic and industrial research groups involved in the development of photoionization methods for mass spectrometry, this reference for analytical scientists covers both the theory and current applications of photo-induced ionization processes. It places widely used techniques such as MALDI side by side with more specialist approaches such as REMPI and RIMS, and discusses leading edge developments in ultrashort laser pulse desorption, to give readers a complete picture of the state of the technology. Photoionization and Photo-Induced Processes in Mass Spectrometry: Fundamentals and Applications starts with a complete overview of the fundamentals of the technique, covering the basics of the gas phase ionization as well as those of laser desorption and ablation, pulse photoionization, and single particle ionization. Numerous application examples from different analytical fields are described that showcase the power and the wide scope of photo ionization in mass spectrometry. -The first general reference book on photoionization techniques for mass spectrometry -Examines technologies and applications of gas phase resonance-enhanced multiphoton ionization mass spectrometry (REMPI-MS) and gas phase resonance ionization mass spectrometry (RIMS) -Provides complete coverage of popular techniques like MALDI -Discusses the current and potential applications of each technology, focusing on process and environmental analysis Photoionization and Photo-Induced Processes in Mass Spectrometry: Fundamentals and Applications is an excellent book for spectroscopists, analytical chemists, photochemists, physical chemists, and laser specialists.

Mass Spectrometry

Author : Jürgen H Gross
Publisher : Springer Science & Business Media
ISBN 13 : 3540407391
Total Pages : 534 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Mass Spectrometry by : Jürgen H Gross

Download or read book Mass Spectrometry written by Jürgen H Gross and published by Springer Science & Business Media. This book was released on 2006-04-05 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.

MALDI MS

Author : Franz Hillenkamp
Publisher : John Wiley & Sons
ISBN 13 : 3527333312
Total Pages : 0 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis MALDI MS by : Franz Hillenkamp

Download or read book MALDI MS written by Franz Hillenkamp and published by John Wiley & Sons. This book was released on 2013-12-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative book on MALDI MS, now finally available in its second edition and edited by one of its inventors, gives an in-depth description of the many different applications, along with a detailed discussion of the technology itself. Thoroughly updated and expanded, with contributions from key players in the field, this unique book provides a comprehensive overview of MALDI MS along with its possibilities and limitations. The initial chapters deal with the technology and the instrumental setup, followed by chapters on the use of MALDI MS in protein research (including proteomics), genomics, glycomics and lipidomics. The option of MALDI-MS for the analysis of polymers and small molecules are also covered in separate chapters, while new to this edition is a section devoted to the interplay of MALDI MS and bioinformatics. A much-needed practical and educational asset for individuals, academic institutions and companies in the field of bioanalytics.

Handbook of Smart Materials in Analytical Chemistry

Author : Miguel de la Guardia
Publisher : John Wiley & Sons
ISBN 13 : 1119422612
Total Pages : 1108 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Handbook of Smart Materials in Analytical Chemistry by : Miguel de la Guardia

Download or read book Handbook of Smart Materials in Analytical Chemistry written by Miguel de la Guardia and published by John Wiley & Sons. This book was released on 2019-01-22 with total page 1108 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to smart materials and how they are used in sample preparation, analytical processes, and applications This comprehensive, two-volume handbook provides detailed information on the present state of new materials tailored for selective sample preparation and the legal frame and environmental side effects of the use of smart materials for sample preparation in analytical chemistry, as well as their use in the analytical processes and applications. It covers both methodological and applied analytical aspects, relating to the development and application of new materials for solid-phase extraction (SPE) and solid-phase microextraction (SPME), their use in the different steps and techniques of the analytical process, and their application in specific fields such as water, food, air, pharmaceuticals, clinical sciences and forensics. Every chapter in Handbook of Smart Materials in Analytical Chemistry is written by experts in the field to provide a comprehensive picture of the present state of this key area of analytical sciences and to summarize current applications and research literature in a critical way. Volume 1 covers New Materials for Sample Preparation and Analysis. Volume 2 handles Analytical Processes and Applications. Focuses on the development and applications of smart materials in analytical chemistry Covers both, methodological and applied analytical aspects, for the development of new materials and their use in the different steps and techniques of the analytical process and their application in specific fields Features applications in key areas including water, air, environment, pharma, food, forensic, and clinical Presents the available tools for the use of new materials suitable to aid recognition process to the sample preparation and analysis A key resource for analytical chemists, applied laboratories, and instrument companies Handbook of Smart Materials in Analytical Chemistry, 2V Set is an excellent reference book for specialists and advanced students in the areas of analytical chemistry, including both research and application environments.

MALDI-TOF and Tandem MS for Clinical Microbiology

Author : Haroun N. Shah
Publisher : John Wiley & Sons
ISBN 13 : 1118960238
Total Pages : 850 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis MALDI-TOF and Tandem MS for Clinical Microbiology by : Haroun N. Shah

Download or read book MALDI-TOF and Tandem MS for Clinical Microbiology written by Haroun N. Shah and published by John Wiley & Sons. This book was released on 2017-03-31 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the triumph of MALDI-TOF mass spectrometry over the past decade and provides insight into new and expanding technologies through a comprehensive range of short chapters that enable the reader to gauge their current status and how they may progress over the next decade. This book serves as a platform to consolidate current strengths of the technology and highlight new frontiers in tandem MS/MS that are likely to eventually supersede MALDI-TOF MS. Chapters discuss: Challenges of Identifying Mycobacterium to the Species level Identification of Bacteroides and Other Clinically Relevant Anaerobes Identification of Species in Mixed Microbial Populations Detection of Resistance Mechanisms Proteomics as a biomarker discovery and validation platform Determination of Antimicrobial Resistance using Tandem Mass Spectrometry

MALDI Mass Spectrometry Imaging

Author : Tiffany Siegel Porta
Publisher : Royal Society of Chemistry
ISBN 13 : 1839162414
Total Pages : 541 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis MALDI Mass Spectrometry Imaging by : Tiffany Siegel Porta

Download or read book MALDI Mass Spectrometry Imaging written by Tiffany Siegel Porta and published by Royal Society of Chemistry. This book was released on 2021-12-03 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers knowledge about matrix-assisted laser desorption ionisation (MALDI) mass spectrometry imaging for postgraduate and professional researchers in academia and in industry where it has direct application to clinical research.

Lipid Analysis

Author : W. W. Christie
Publisher : Elsevier
ISBN 13 : 0857097865
Total Pages : 447 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Lipid Analysis by : W. W. Christie

Download or read book Lipid Analysis written by W. W. Christie and published by Elsevier. This book was released on 2010-01-10 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This well-known and highly successful book was first published in 1973 and has been completely re-written in subsequent editions (published in 1982 and 2003). This new Fourth Edition has become necessary because of the pace of developments in mass spectrometry of intact lipids, which has given recognition of lipid analysis and ‘lipidomics’ as a distinct science. To bring the book up to date with these developments, author William W. Christie is joined by co-author Xianlin Han. Although devoting considerable space to mass spectrometry and lipidomics, Lipid analysis remains a practical guide, in one volume, to the complexities of the analysis of lipids. As in past editions, it is designed to act as a primary source, of value at the laboratory bench rather than residing on a library shelf. Lipid analysis deals with the isolation, separation, identification and structural analysis of glycerolipids, including triacylglycerols, phospholipids, sphingolipids, and the various hydrolysis products of these. The chapters follow a logical sequence from the extraction of lipids to the isolation and characterization of particular lipid classes and of molecular species of each, and to the mass spectrometric analysis of lipids and lipidomics. The new influence of mass spectrometry is due mainly to the development of electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI). Most emphasis in this book is placed on ESI, which is enabling structural characterization of different lipid classes and the identification of novel lipids and their molecular species.

Advancements of Mass Spectrometry in Biomedical Research

Author : Alisa G. Woods
Publisher : Springer
ISBN 13 : 3319060686
Total Pages : 601 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Advancements of Mass Spectrometry in Biomedical Research by : Alisa G. Woods

Download or read book Advancements of Mass Spectrometry in Biomedical Research written by Alisa G. Woods and published by Springer. This book was released on 2014-06-20 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine.

100 Years of Human Chorionic Gonadotropin

Author : Laurence A. Cole
Publisher : Elsevier
ISBN 13 : 0128216093
Total Pages : 360 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis 100 Years of Human Chorionic Gonadotropin by : Laurence A. Cole

Download or read book 100 Years of Human Chorionic Gonadotropin written by Laurence A. Cole and published by Elsevier. This book was released on 2020-02-07 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: 100 years of Human Chorionic Gonadotropin: Reviews and New Perspectives is a collection of articles written by some of the world's leading experts on the pregnancy hormone and cancer marker hCG. In 2019 it is difficult to ignore the effect that our understanding of hCG has had on the lives of millions of people worldwide. The hCG immunoassay, in one form or another, is now one of the most common medical tests conducted and is often the first indication that a mother-to-be is pregnant. Not only a marker of pregnancy, hCG is utilized in the diagnosis and monitoring in oncology and presents a potential target for novel cancer therapeutics. 100 years ago, in 1919, Hirose was demonstrating gonadotropic functions which resulted from a chorionic factor. Over the last century this factor has become defined as hCG and more recently explored as not one molecule but a group of molecules with variable structure and variable functions in both pregnancy and cancer. hCG is a multi-faceted molecule that has clinical and therapeutic implications but can be a challenging topic for researchers and physicians alike. This text covers the different structures and functions of hCG exploring the genes and evolution of the molecule, the different protein and glycosylation structures which can exist and their effect on structure, detection and quantification. 100 Years of hCG is not an attempt to recount the history of every publication on hCG, but rather a collection of reviews and new perspectives by "hCG-ologists", the term used by Hussa to describe biochemists working on HCG in the first book written on the topic over 30 years ago. Some of the authors have been around a while, some not so long, but others are just beginning their journey with a most beguiling molecule. - Provides updated information on a complex and changing subject in five sections - Reviews historical perspectives and developments over the last 100 years - Includes novel insights into the structure, function and detection of hCG in pregnancy and cancer - Includes chapters on the use of mass spectrometry to detect and quantify hCG as well as traditional immunoassays and over the counter pregnancy tests - Describes the role of hCG in pregnancy, endometrial receptivity and embryo implantation and the use in fertility treatment - Addresses the specific hyperglycosylated hCG test that can distinguish a normal term from a failing pregnancy and also screen for preeclampsia and gestational hypertension in pregnancy as well as its use as a marker and treatment target in cancer. - Includes chapters on the development and use of hCG vaccines - Includes a section on hCG and in subunits in cancer

Analyzing Biomolecular Interactions by Mass Spectrometry

Author : Jeroen Kool
Publisher : John Wiley & Sons
ISBN 13 : 3527334645
Total Pages : 402 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Analyzing Biomolecular Interactions by Mass Spectrometry by : Jeroen Kool

Download or read book Analyzing Biomolecular Interactions by Mass Spectrometry written by Jeroen Kool and published by John Wiley & Sons. This book was released on 2015-05-04 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomics and interactomics. The third and final part discusses other important technologies frequently employed in interaction studies, such as biosensors and microarrays. For pharmaceutical, analytical, protein, environmental and biochemists, as well as those working in pharmaceutical and analytical laboratories.

Ionization Methods in Organic Mass Spectrometry

Author : Alison E Ashcroft
Publisher : Royal Society of Chemistry
ISBN 13 : 184755119X
Total Pages : 188 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Ionization Methods in Organic Mass Spectrometry by : Alison E Ashcroft

Download or read book Ionization Methods in Organic Mass Spectrometry written by Alison E Ashcroft and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ionization Methods in Organic Mass Spectrometry is a basic practical guide for scientists of all disciplines who wish to analyse samples by organic mass spectrometry. Concentrating on instrumental operation, this book gives step-by-step instructions on how to set up, and how to achieve the best results, using a range of ionization methods, including atmospheric pressure chemical ionization, electrospray ionization and matrix assisted laser desorption ionization. Ionization Methods in Organic Mass Spectrometry will enable a beginner, or practitioner with limited experience, to choose the most appropriate ionization technique in application areas such as biomolecules, drugs and metabolites, pesticides, polymers and many other organic compounds. It will be a valuable practical guide for technicians, graduates, students or researchers - or indeed anyone new to practical organic mass spectrometry.

Molecular Tools and Infectious Disease Epidemiology

Author : Betsy Foxman
Publisher : Academic Press
ISBN 13 : 0080920845
Total Pages : 228 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Molecular Tools and Infectious Disease Epidemiology by : Betsy Foxman

Download or read book Molecular Tools and Infectious Disease Epidemiology written by Betsy Foxman and published by Academic Press. This book was released on 2010-12-28 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Tools and Infectious Disease Epidemiology examines the opportunities and methodologic challenges in the application of modern molecular genetic and biologic techniques to infectious disease epidemiology. The application of these techniques dramatically improves the measurement of disease and putative risk factors, increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. This book presents the key points of consideration when integrating molecular biology and epidemiology; discusses how using molecular tools in epidemiologic research affects program design and conduct; considers the ethical concerns that arise in molecular epidemiologic studies; and provides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field. The book is recommended for graduate and advanced undergraduate students studying infectious disease epidemiology and molecular epidemiology; and for the epidemiologist wishing to integrate molecular techniques into his or her studies. - Presents the key points of consideration when integrating molecular biology and epidemiology - Discusses how using molecular tools in epidemiologic research affects program design and conduct - Considers the ethical concerns that arise in molecular epidemiologic studies - Provides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field

Ion Mobility Spectrometry - Mass Spectrometry

Author : Charles L. Wilkins
Publisher : CRC Press
ISBN 13 : 1439813256
Total Pages : 374 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Ion Mobility Spectrometry - Mass Spectrometry by : Charles L. Wilkins

Download or read book Ion Mobility Spectrometry - Mass Spectrometry written by Charles L. Wilkins and published by CRC Press. This book was released on 2010-12-14 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: The analytical power of ion mobility spectrometry-mass spectrometry (IMS-MS) instruments is poised to advance this technology from research to analytical laboratories. Exploring these developments at this critical juncture, Ion Mobility Spectrometry-Mass Spectrometry: Theory and Applications covers the tools, techniques, and applications involved w

The Use of Mass Spectrometry Technology (MALDI-TOF) in Clinical Microbiology

Author : Fernando Cobo
Publisher : Academic Press
ISBN 13 : 0128144521
Total Pages : 299 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Use of Mass Spectrometry Technology (MALDI-TOF) in Clinical Microbiology by : Fernando Cobo

Download or read book The Use of Mass Spectrometry Technology (MALDI-TOF) in Clinical Microbiology written by Fernando Cobo and published by Academic Press. This book was released on 2018-08-03 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Use of Mass Spectrometry Technology (MALDI-TOF) in Clinical Microbiology presents the state-of the-art for MALDI-TOF mass spectrometry. It is a key reference defining how MALDI-TOF mass spectrometry is used in clinical settings as a diagnostic tool of microbial identification and characterization that is based on the detection of a mass of molecules. The book provides updated applications of MALDI-TOF techniques in clinical microbiology, presenting the latest information available on a technology that is now used for rapid microbial identification at relatively low cost, thus offering an alternative to conventional laboratory diagnosis and proteomic identification systems. Although the main use of the technology has, until now, been identification or typing of bacteria from a positive culture, applications in the field of virology, mycology, microbacteriology and resistances are opening up new opportunities. - Presents updated applications of MALDI-TOF techniques in clinical microbiology - Describes the use of mass spectrometry in the lab, the principles of the technology, preparation of samples, device calibration and maintenance, treatment of microorganisms, and quality control - Presents key information for researchers, including possible uses of the technology, differences between devices, how to interpret results, and future applications - Covers the topic in a systematic and comprehensive manner that is useful to both clinicians and researchers

Encyclopedia of Mass Spectrometry

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (2 download)

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Book Synopsis Encyclopedia of Mass Spectrometry by :

Download or read book Encyclopedia of Mass Spectrometry written by and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Integration of Omics Approaches and Systems Biology for Clinical Applications

Author : Antonia Vlahou
Publisher : John Wiley & Sons
ISBN 13 : 1119181143
Total Pages : 386 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Integration of Omics Approaches and Systems Biology for Clinical Applications by : Antonia Vlahou

Download or read book Integration of Omics Approaches and Systems Biology for Clinical Applications written by Antonia Vlahou and published by John Wiley & Sons. This book was released on 2018-02-21 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis is put on integration of data generated from these different platforms in order to uncover the molecular landscape of diseases. The relevance of each approach to the clinical setting is explained and future applications for patient monitoring or treatment are discussed. Integration of omics Approaches and Systems Biology for Clinical Applications presents an overview of state of the art omics techniques. These methods are employed in order to obtain the comprehensive molecular profile of biological specimens. In addition, computational tools are used for organizing and integrating these multi-source data towards developing molecular models that reflect the pathophysiology of diseases. Investigation of chronic kidney disease (CKD) and bladder cancer are used as test cases. These represent multi-factorial, highly heterogeneous diseases, and are among the most significant health issues in developed countries with a rapidly aging population. The book presents novel insights on CKD and bladder cancer obtained by omics data integration as an example of the application of systems biology in the clinical setting. Describes a range of state of the art omics analytical platforms Covers all aspects of the systems biology approach—from sample preparation to data integration and bioinformatics analysis Contains specific examples of omics methods applied in the investigation of human diseases (Chronic Kidney Disease, Bladder Cancer) Integration of omics Approaches and Systems Biology for Clinical Applications will appeal to a wide spectrum of scientists including biologists, biotechnologists, biochemists, biophysicists, and bioinformaticians working on the different molecular platforms. It is also an excellent text for students interested in these fields.

Ion Mobility-Mass Spectrometry

Author : Giuseppe Paglia
Publisher : Humana
ISBN 13 : 9781071600290
Total Pages : 0 pages
Book Rating : 4.6/5 (2 download)

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Book Synopsis Ion Mobility-Mass Spectrometry by : Giuseppe Paglia

Download or read book Ion Mobility-Mass Spectrometry written by Giuseppe Paglia and published by Humana. This book was released on 2019-11-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on ion mobility-mass spectrometry (IM-MS) and informatics approaches to improve traditional analysis of molecules by providing fundamentals and protocols for exploiting the potential of state-of-the-art IM-MS technology for the most common analytical applications. The chapters have been organized into four parts, each dealing with a particular set of IM-MS applications: 1) metabolomics and lipidomics; 2) proteomics and glycomics; 3) imaging and ambient ionization IM-MS; and 4) bioinformatic solutions for analyzing IM-MS data and deriving CCS values. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Ion Mobility-Mass Spectrometry: Methods and Protocols serves as an ideal resource for scientists delving into the technique's unprecedented analytical advantages, enabling novel qualitative and quantitative applications for the analysis of complex biological samples.