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Mathematical Models And Methods For Living Systems
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Book Synopsis Mathematical Modeling in Systems Biology by : Brian P. Ingalls
Download or read book Mathematical Modeling in Systems Biology written by Brian P. Ingalls and published by MIT Press. This book was released on 2022-06-07 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.
Book Synopsis Mathematical Models and Methods for Living Systems by : Luigi Preziosi
Download or read book Mathematical Models and Methods for Living Systems written by Luigi Preziosi and published by Springer. This book was released on 2016-11-09 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of these lecture notes is to give an introduction to several mathematical models and methods that can be used to describe the behaviour of living systems. This emerging field of application intrinsically requires the handling of phenomena occurring at different spatial scales and hence the use of multiscale methods.Modelling and simulating the mechanisms that cells use to move, self-organise and develop in tissues is not only fundamental to an understanding of embryonic development, but is also relevant in tissue engineering and in other environmental and industrial processes involving the growth and homeostasis of biological systems. Growth and organization processes are also important in many tissue degeneration and regeneration processes, such as tumour growth, tissue vascularization, heart and muscle functionality, and cardio-vascular diseases.
Book Synopsis A Biologist's Guide to Mathematical Modeling in Ecology and Evolution by : Sarah P. Otto
Download or read book A Biologist's Guide to Mathematical Modeling in Ecology and Evolution written by Sarah P. Otto and published by Princeton University Press. This book was released on 2011-09-19 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirty years ago, biologists could get by with a rudimentary grasp of mathematics and modeling. Not so today. In seeking to answer fundamental questions about how biological systems function and change over time, the modern biologist is as likely to rely on sophisticated mathematical and computer-based models as traditional fieldwork. In this book, Sarah Otto and Troy Day provide biology students with the tools necessary to both interpret models and to build their own. The book starts at an elementary level of mathematical modeling, assuming that the reader has had high school mathematics and first-year calculus. Otto and Day then gradually build in depth and complexity, from classic models in ecology and evolution to more intricate class-structured and probabilistic models. The authors provide primers with instructive exercises to introduce readers to the more advanced subjects of linear algebra and probability theory. Through examples, they describe how models have been used to understand such topics as the spread of HIV, chaos, the age structure of a country, speciation, and extinction. Ecologists and evolutionary biologists today need enough mathematical training to be able to assess the power and limits of biological models and to develop theories and models themselves. This innovative book will be an indispensable guide to the world of mathematical models for the next generation of biologists. A how-to guide for developing new mathematical models in biology Provides step-by-step recipes for constructing and analyzing models Interesting biological applications Explores classical models in ecology and evolution Questions at the end of every chapter Primers cover important mathematical topics Exercises with answers Appendixes summarize useful rules Labs and advanced material available
Book Synopsis Mathematical Modeling for the Life Sciences by : Jacques Istas
Download or read book Mathematical Modeling for the Life Sciences written by Jacques Istas and published by Springer Science & Business Media. This book was released on 2005-10-04 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a wide range of mathematical models currently used in the life sciences Each model is thoroughly explained and illustrated by example Includes three appendices to allow for independent reading
Book Synopsis Systems Biology by : Andreas Kremling
Download or read book Systems Biology written by Andreas Kremling and published by CRC Press. This book was released on 2013-11-12 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on the latest research in the field, Systems Biology: Mathematical Modeling and Model Analysis presents many methods for modeling and analyzing biological systems, in particular cellular systems. It shows how to use predictive mathematical models to acquire and analyze knowledge about cellular systems. It also explores how the models are systematically applied in biotechnology. The first part of the book introduces biological basics, such as metabolism, signaling, gene expression, and control as well as mathematical modeling fundamentals, including deterministic models and thermodynamics. The text also discusses linear regression methods, explains the differences between linear and nonlinear regression, and illustrates how to determine input variables to improve estimation accuracy during experimental design. The second part covers intracellular processes, including enzymatic reactions, polymerization processes, and signal transduction. The author highlights the process–function–behavior sequence in cells and shows how modeling and analysis of signal transduction units play a mediating role between process and function. The third part presents theoretical methods that address the dynamics of subsystems and the behavior near a steady state. It covers techniques for determining different time scales, sensitivity analysis, structural kinetic modeling, and theoretical control engineering aspects, including a method for robust control. It also explores frequent patterns (motifs) in biochemical networks, such as the feed-forward loop in the transcriptional network of E. coli. Moving on to models that describe a large number of individual reactions, the last part looks at how these cellular models are used in biotechnology. The book also explains how graphs can illustrate the link between two components in large networks with several interactions.
Book Synopsis Mathematical Modeling of Biological Systems, Volume II by : Andreas Deutsch
Download or read book Mathematical Modeling of Biological Systems, Volume II written by Andreas Deutsch and published by Springer Science & Business Media. This book was released on 2007-10-12 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume II of this two-volume, interdisciplinary work is a unified presentation of a broad range of state-of-the-art topics in the rapidly growing field of mathematical modeling in the biological sciences. Highlighted throughout are mathematical and computational apporaches to examine central problems in the life sciences, ranging from the organization principles of individual cells to the dynamics of large populations. The chapters are thematically organized into the following main areas: epidemiology, evolution and ecology, immunology, neural systems and the brain, and innovative mathematical methods and education. The work will be an excellent reference text for a broad audience of researchers, practitioners, and advanced students in this rapidly growing field at the intersection of applied mathematics, experimental biology and medicine, computational biology, biochemistry, computer science, and physics.
Download or read book Modeling Life written by Alan Garfinkel and published by Springer. This book was released on 2017-09-06 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?
Book Synopsis Mathematical Modelling in Health, Social and Applied Sciences by : Hemen Dutta
Download or read book Mathematical Modelling in Health, Social and Applied Sciences written by Hemen Dutta and published by Springer Nature. This book was released on 2020-02-29 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses significant research findings in the field of mathematical modelling, with particular emphasis on important applied-sciences, health, and social issues. It includes topics such as model on viral immunology, stochastic models for the dynamics of influenza, model describing the transmission of dengue, model for human papillomavirus (HPV) infection, prostate cancer model, realization of economic growth by goal programming, modelling of grazing periodic solutions in discontinuous systems, modelling of predation system, fractional epidemiological model for computer viruses, and nonlinear ecological models. A unique addition in the proposed areas of research and education, this book is a valuable resource for graduate students, researchers and educators associated with the study of mathematical modelling of health, social and applied-sciences issues. Readers interested in applied mathematics should also find this book valuable.
Book Synopsis Systems Biology by : Andreas Kremling
Download or read book Systems Biology written by Andreas Kremling and published by CRC Press. This book was released on 2013-11-12 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on the latest research in the field, Systems Biology: Mathematical Modeling and Model Analysis presents many methods for modeling and analyzing biological systems, in particular cellular systems. It shows how to use predictive mathematical models to acquire and analyze knowledge about cellular systems. It also explores how the models are sy
Book Synopsis Mathematical Models in Biology by : Valeria Zazzu
Download or read book Mathematical Models in Biology written by Valeria Zazzu and published by Springer. This book was released on 2015-11-26 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an exciting collection of contributions based on the workshop “Bringing Maths to Life” held October 27-29, 2014 in Naples, Italy. The state-of-the art research in biology and the statistical and analytical challenges facing huge masses of data collection are treated in this Work. Specific topics explored in depth surround the sessions and special invited sessions of the workshop and include genetic variability via differential expression, molecular dynamics and modeling, complex biological systems viewed from quantitative models, and microscopy images processing, to name several. In depth discussions of the mathematical analysis required to extract insights from complex bodies of biological datasets, to aid development in the field novel algorithms, methods and software tools for genetic variability, molecular dynamics, and complex biological systems are presented in this book. Researchers and graduate students in biology, life science, and mathematics/statistics will find the content useful as it addresses existing challenges in identifying the gaps between mathematical modeling and biological research. The shared solutions will aid and promote further collaboration between life sciences and mathematics.
Book Synopsis Mathematical Models in Biology by : Leah Edelstein-Keshet
Download or read book Mathematical Models in Biology written by Leah Edelstein-Keshet and published by SIAM. This book was released on 1988-01-01 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Models in Biology is an introductory book for readers interested in biological applications of mathematics and modeling in biology. A favorite in the mathematical biology community, it shows how relatively simple mathematics can be applied to a variety of models to draw interesting conclusions. Connections are made between diverse biological examples linked by common mathematical themes. A variety of discrete and continuous ordinary and partial differential equation models are explored. Although great advances have taken place in many of the topics covered, the simple lessons contained in this book are still important and informative. Audience: the book does not assume too much background knowledge--essentially some calculus and high-school algebra. It was originally written with third- and fourth-year undergraduate mathematical-biology majors in mind; however, it was picked up by beginning graduate students as well as researchers in math (and some in biology) who wanted to learn about this field.
Book Synopsis Modeling Complex Living Systems by : N. Bellomo
Download or read book Modeling Complex Living Systems written by N. Bellomo and published by Springer Science & Business Media. This book was released on 2008 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Develops different mathematical methods and tools to model living systems. This book presents material that can be used in such real-world applications as immunology, transportation engineering, and economics. It is of interest to those involved in modeling complex social systems and living matter in general.
Book Synopsis Mathematical Modeling of Biological Processes by : Avner Friedman
Download or read book Mathematical Modeling of Biological Processes written by Avner Friedman and published by Springer. This book was released on 2014-09-19 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on mathematical modeling of biological processes includes a wide selection of biological topics that demonstrate the power of mathematics and computational codes in setting up biological processes with a rigorous and predictive framework. Topics include: enzyme dynamics, spread of disease, harvesting bacteria, competition among live species, neuronal oscillations, transport of neurofilaments in axon, cancer and cancer therapy, and granulomas. Complete with a description of the biological background and biological question that requires the use of mathematics, this book is developed for graduate students and advanced undergraduate students with only basic knowledge of ordinary differential equations and partial differential equations; background in biology is not required. Students will gain knowledge on how to program with MATLAB without previous programming experience and how to use codes in order to test biological hypothesis.
Book Synopsis Mathematical Modelling Techniques by : Rutherford Aris
Download or read book Mathematical Modelling Techniques written by Rutherford Aris and published by Courier Corporation. This book was released on 1994-01-01 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Engaging, elegantly written." — Applied Mathematical Modelling. A distinguished theoretical chemist and engineer discusses the types of models — finite, statistical, stochastic, and more — as well as how to formulate and manipulate them for best results. Filled with numerous examples, the book includes three appendices offering further examples treated in more detail.
Book Synopsis Methods and Models in Mathematical Biology by : Johannes Müller
Download or read book Methods and Models in Mathematical Biology written by Johannes Müller and published by Springer. This book was released on 2015-08-13 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book developed from classes in mathematical biology taught by the authors over several years at the Technische Universität München. The main themes are modeling principles, mathematical principles for the analysis of these models and model-based analysis of data. The key topics of modern biomathematics are covered: ecology, epidemiology, biochemistry, regulatory networks, neuronal networks and population genetics. A variety of mathematical methods are introduced, ranging from ordinary and partial differential equations to stochastic graph theory and branching processes. A special emphasis is placed on the interplay between stochastic and deterministic models.
Book Synopsis Mathematical Methods and Models in Biomedicine by : Urszula Ledzewicz
Download or read book Mathematical Methods and Models in Biomedicine written by Urszula Ledzewicz and published by Springer Science & Business Media. This book was released on 2012-10-20 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical biomedicine is a rapidly developing interdisciplinary field of research that connects the natural and exact sciences in an attempt to respond to the modeling and simulation challenges raised by biology and medicine. There exist a large number of mathematical methods and procedures that can be brought in to meet these challenges and this book presents a palette of such tools ranging from discrete cellular automata to cell population based models described by ordinary differential equations to nonlinear partial differential equations representing complex time- and space-dependent continuous processes. Both stochastic and deterministic methods are employed to analyze biological phenomena in various temporal and spatial settings. This book illustrates the breadth and depth of research opportunities that exist in the general field of mathematical biomedicine by highlighting some of the fascinating interactions that continue to develop between the mathematical and biomedical sciences. It consists of five parts that can be read independently, but are arranged to give the reader a broader picture of specific research topics and the mathematical tools that are being applied in its modeling and analysis. The main areas covered include immune system modeling, blood vessel dynamics, cancer modeling and treatment, and epidemiology. The chapters address topics that are at the forefront of current biomedical research such as cancer stem cells, immunodominance and viral epitopes, aggressive forms of brain cancer, or gene therapy. The presentations highlight how mathematical modeling can enhance biomedical understanding and will be of interest to both the mathematical and the biomedical communities including researchers already working in the field as well as those who might consider entering it. Much of the material is presented in a way that gives graduate students and young researchers a starting point for their own work.
Author :Vadrevu Sree Hari Rao Publisher :Springer Science & Business Media ISBN 13 :1441903593 Total Pages :279 pages Book Rating :4.4/5 (419 download)
Book Synopsis Dynamic Models and Control of Biological Systems by : Vadrevu Sree Hari Rao
Download or read book Dynamic Models and Control of Biological Systems written by Vadrevu Sree Hari Rao and published by Springer Science & Business Media. This book was released on 2009-07-30 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Biology has grown at an astonishing rate and has established itself as a distinct discipline. Mathematical modeling is now being applied in every major discipline in the biological sciences. Though the field has become increasingly large and specialized, this book remains important as a text that introduces some of the exciting problems which arise in the biological sciences and gives some indication of the wide spectrum of questions that modeling can address.
