Mammaglobin And Lipophilin Related Molecules In Normal And Tumor Human Breast Tissue Expression Hormone Regulation And Functional Analysis

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Early Detection of Breast Cancer

Author : S. Brünner
Publisher : Springer Science & Business Media
ISBN 13 : 364282031X
Total Pages : 253 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Early Detection of Breast Cancer by : S. Brünner

Download or read book Early Detection of Breast Cancer written by S. Brünner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enormous expansion seen over the last decade in the mammo graphic detection of breast cancer lesions, especially the use of screen ing procedures for the early detection of clinically unsuspected tumors, has made it necessary to summarize the experience made by various centers in the world. The 2nd International Copenhagen Symposium on Detection of Breast Cancer afforded an opportunity of gathering scientists from all over the world to discuss the various problems of early breast cancer detection with special reference to screening procedures. This book forms a synthesis of the information presented by leading scientists from many of the world's mammo graphic centers, particularly those in Sweden and the USA. Hence, the reader will have the opportunity to study the outstanding work carried out by various institutes and centers of breast cancer screening. It is our sincere hope that a study of this volume will encourage other scientists to join in the work on screening procedures. S. Brunner B. Langfeldt P. E. Andersen Contents S. A. Feig: 1 Hypothetical Breast Cancer Risk from Mammography S. A. Feig: Benefits and Risks of Mammography 11 R. L. Egan and M. B. McSweeney: Multicentric Breast Carcinoma . . . . . . . . . . . . . . . . . . . . . . . . 28 M. B. McSweeney and R. L. Egan: Breast Cancer in the Younger Patient: A Preliminary Report 36 M. B. McSweeney and R. L. Egan: Bilateral Breast Carcinoma . . . . . . . . . . . . . . . . . . . . . . . . . . . ' 41 N. Bjurstam: The Radiographic Appearance of Normal and Metastatic Axillary Lymph Nodes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 M. Moskowitz, S. A. Feig, C. Cole-Beuglet, S. H.

Clinical Gynecology

Author : Eric J. Bieber
Publisher : Cambridge University Press
ISBN 13 : 1107040396
Total Pages : 1127 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Clinical Gynecology by : Eric J. Bieber

Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.

New Trends in Cancer for the 21st Century

Author : Antonio Llombart Bosch
Publisher : Springer Science & Business Media
ISBN 13 : 9780306477621
Total Pages : 312 pages
Book Rating : 4.4/5 (776 download)

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Book Synopsis New Trends in Cancer for the 21st Century by : Antonio Llombart Bosch

Download or read book New Trends in Cancer for the 21st Century written by Antonio Llombart Bosch and published by Springer Science & Business Media. This book was released on 2003 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest advances in cancer research include basic research and its derived diagnostic, clinical and therapeutic applications. The book New Trends in Cancer for the 21st Century is written by individuals such as: molecular biologists whose tasks are, after sequencing the human genome, to decipher those new genes and pathways involved in the carcinogenesis process; clinical and molecular pathologists, who apply these discoveries for the molecular diagnosis and characterization of the tumour; and clinical oncologists, who treat patients. Pharmacogenetics introduces new perspectives in the translational fields with the design of drugs against specific targets, which are in clinical trials phases in 2003. Several organizations such as the EORTC (European Organization for Research and Treatment of Cancer) and the OECI (Organization of European Cancer Institutes) and comprehensive cancer centres play a crucial role in focusing cancer research on all these areas.

Shed Tears for Diagnostics

Author : Anjali Prashar
Publisher : Springer
ISBN 13 : 9811371695
Total Pages : 177 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Shed Tears for Diagnostics by : Anjali Prashar

Download or read book Shed Tears for Diagnostics written by Anjali Prashar and published by Springer. This book was released on 2019-06-17 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers a wide range of topics concerning human tear based science, starting from basics such as the normal composition of tears and moving up to novel disease detection platforms. The entire approach is pioneering, as tears are beginning to be recognized as the most invaluable non-invasive tool in diagnostics. Interestingly, the concept is not restricted to ocular diseases: In recent years, tear diagnostics is increasingly being tapped even for cancer detection. Hopefully, non-invasive tear diagnostics will eventually replace today’s invasive disease detection and monitoring techniques. Previous literature on tear diagnostics has been restricted to scientific journal articles, most of which dealt with a single tear constituent, such as a protein. This book offers a far more comprehensive and handy ‘reference guide,’ presenting both basic and advanced information and data. Accordingly, it will be useful for researchers in academia and the pharmaceutical industry, as well as healthcare professionals and diagnostic kit developers.

The Uteroglobin/Clara Cell Protein Family

Author : Anil B. Mukherjee
Publisher :
ISBN 13 :
Total Pages : 378 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis The Uteroglobin/Clara Cell Protein Family by : Anil B. Mukherjee

Download or read book The Uteroglobin/Clara Cell Protein Family written by Anil B. Mukherjee and published by . This book was released on 2000 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of this family of proteins three decades ago launched a broad range of research effort that now reaches across many potential applications in human reproductive biology, inflammatory diseases, endocrinology, and in oncology. These proceedings papers extend the new function research possibilities inherent in the structure of this steroid-inducible, multifunctional secreted protein, and in the UG-bioactive-derived peptides. An opening overview of the UG family focuses on mammaglobin and its implications with human breast cancer; the sequence/structure sections review applications of antiflammin responses from its peptide. Other sections present new research on regulation of uteroglobin genes by cytokines and hormones; and clinical applications for renal diseases, in targeting gene therapy in pulmonary disease. Together, these developments raise the possibility of cytokine/chemokine-like functions that play important roles in major public health problems. A consensus of nomenclature for Uteroglobin/Clara Cell 10kDa family of proteins is also advanced as a step to coordinating new areas of research for these promising proteins and receptors.

Immunotherapy – A Novel Facet of Modern Therapeutics

Author : Sujata P. Sawarkar
Publisher : Springer Nature
ISBN 13 : 9811590389
Total Pages : 267 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Immunotherapy – A Novel Facet of Modern Therapeutics by : Sujata P. Sawarkar

Download or read book Immunotherapy – A Novel Facet of Modern Therapeutics written by Sujata P. Sawarkar and published by Springer Nature. This book was released on 2020-12-16 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates the significance and relevance of immunotherapy in modern-day therapeutics. Focusing on the application of immunotherapy in oncology, neurodegenerative and autoimmune diseases, it discusses the drug delivery systems, and pre-clinical and clinical methodologies for immunotherapy-based drugs. It also comprehensively reviews various aspects of immunotherapy, such as regulatory affairs, quality control, safety, and pharmacovigilance. Further, the book discusses the in vitro validation of therapeutic strategies prior to patient application and management of immunotherapy-related side effects and presents case studies demonstrating the design and development (pre-clinical to clinical) of immunotherapy for various diseases. It also describes various design considerations and the scale-up synthesis of immunotherapeutics and screening methods. Lastly, it explores the important aspect of cost-effectiveness and rational immunotherapy strategies.

Developments in Tryptophan and Serotonin Metabolism

Author : Graziella Allegri
Publisher : Springer Science & Business Media
ISBN 13 : 9780306477553
Total Pages : 810 pages
Book Rating : 4.4/5 (775 download)

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Book Synopsis Developments in Tryptophan and Serotonin Metabolism by : Graziella Allegri

Download or read book Developments in Tryptophan and Serotonin Metabolism written by Graziella Allegri and published by Springer Science & Business Media. This book was released on 2004-01-15 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the proceedings of the Tenth International Meeting of the International Study Group for Tryptophan Research (ISTR V), held at the University of Padova, Padova, Italy, from 25-29 June, 2002 under the auspices of the Ministry of Education, University and Research (MIUR) in Roma, the University of Padova, the Italian Chemical Society - Division of Pharmaceutical Chemistry, the Veneto Region and the City of Padova. The meeting was organized to cover the recent developments in the field of tryptophan research. Weare very honoured that so many speakers accepted our invitation to give plenary lectures which, with the other communications, demonstrated the high scientific value of the Meeting. The publications in this volume are subdivided into nine main chapters, and cover all the major aspects in immunology, neurobiology, psychiatry, pathology, clinics, metabolism, enzymology, pharmacology, toxicology, melatonin, exercise and analytical chemistry. The volume includes the contributions of 325 scientists from 24 countries, and the Musajo Memorial Lecture delivered by Prof. Osamu Hayaishi during the Opening Ceremony.

Contact Lens Complications

Author : Nathan Efron
Publisher :
ISBN 13 :
Total Pages : 292 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Contact Lens Complications by : Nathan Efron

Download or read book Contact Lens Complications written by Nathan Efron and published by . This book was released on 2004 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new 2nd edition of this practical manual has been completely updated and revised to reflect the most current knowledge, research findings, technological developments, and updates in contact lens materials. With its broad coverage and systematic approach, it provides an intuitive approach to understanding, diagnosing, and treating contact lens complications. This lavishly illustrated text is recognized as a definitive resource on contact lens for practitioners and students.

Introduction to Genetics: A Molecular Approach

Author : T A Brown
Publisher : Garland Science
ISBN 13 : 1136665358
Total Pages : 554 pages
Book Rating : 4.1/5 (366 download)

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Book Synopsis Introduction to Genetics: A Molecular Approach by : T A Brown

Download or read book Introduction to Genetics: A Molecular Approach written by T A Brown and published by Garland Science. This book was released on 2012-03-22 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Genetics: A Molecular Approach is a new textbook for first and second year undergraduates. It first presents molecular structures and mechanisms before introducing the more challenging concepts and terminology associated with transmission genetics.

Who Classification of Tumours of the Lung, Pleura, Thymus and Heart

Author : International Agency for Research on Cancer
Publisher : World Health Organization
ISBN 13 : 9789283224365
Total Pages : 410 pages
Book Rating : 4.2/5 (243 download)

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Book Synopsis Who Classification of Tumours of the Lung, Pleura, Thymus and Heart by : International Agency for Research on Cancer

Download or read book Who Classification of Tumours of the Lung, Pleura, Thymus and Heart written by International Agency for Research on Cancer and published by World Health Organization. This book was released on 2015-03-16 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart is the seventh volume in the Fourth Edition of the WHO series on histological and genetic typing of human tumors. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome.

Metabolism in Cancer

Author : Thorsten Cramer
Publisher : Springer
ISBN 13 : 3319421182
Total Pages : 272 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Metabolism in Cancer by : Thorsten Cramer

Download or read book Metabolism in Cancer written by Thorsten Cramer and published by Springer. This book was released on 2016-08-24 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.

Genes and Cancer

Author : Karol Sikora
Publisher : Wiley
ISBN 13 : 9780471925835
Total Pages : 364 pages
Book Rating : 4.9/5 (258 download)

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Book Synopsis Genes and Cancer by : Karol Sikora

Download or read book Genes and Cancer written by Karol Sikora and published by Wiley. This book was released on 1990-10-26 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work serves as an introduction to the applications of molecular biology in the field of oncology. It provides a basic understanding of the genetic events involved in fully developed human cancer, including research into inherited and acquired gene defects initiating new neoplasms and the subsequent genetic alterations involved in tumor progression. Some of the specific topics explored include gene control, molecular therapy and antibodies, drug resistance, growth factors and receptors, and tumor biology. While intended primarily as an advanced text for oncologists, postgraduate molecular geneticists and molecular biologists, the book will certainly be of interest to other researchers who frequently encounter cancer in their practice.

The Innate Immune Response to Noninfectious Stressors

Author : Massimo Amadori
Publisher : Academic Press
ISBN 13 : 0128019743
Total Pages : 278 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Innate Immune Response to Noninfectious Stressors by : Massimo Amadori

Download or read book The Innate Immune Response to Noninfectious Stressors written by Massimo Amadori and published by Academic Press. This book was released on 2016-02-23 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Innate Immune Response to Non-infectious Stressors: Human and Animal Models highlights fundamental mechanisms of stress response and important findings on how the immune system is affected, and in turn affects such a response. In addition, this book covers the crucial link between stress response and energy metabolism, prompts a re-appraisal of some crucial issues, and helps to define research priorities in this fascinating, somehow elusive field of investigation. - Provides insights into the fundamental homeostatic processes vis-à-vis stressors to help in investigation - Illustrates the depicted tenets and how to offset them against established models of response to physical and psychotic stressors in both animals and humans - Covers the crucial issue of the immune response to endocrine disruptors - Includes immunological parameters as reporter system of environmental adaptation - Provides many illustrative examples to foster reader understanding

Methods in Cellular Imaging

Author : Ammasi Periasamy
Publisher : Springer
ISBN 13 : 1461475139
Total Pages : 473 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Methods in Cellular Imaging by : Ammasi Periasamy

Download or read book Methods in Cellular Imaging written by Ammasi Periasamy and published by Springer. This book was released on 2013-05-27 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in technology have revolutionized the development of light microscopy techniques in biomedical research, thus improving visualization of the microstructure of cells and tissues under physiological conditions. Fluorescence microscopy methods are non-contact and non-invasive and provide high spatial and temporal resolution that other laboratory techniques cannot. This well-illustrated book targets graduate students and scientists who are new to the state-of-the-art fluorescence microscopy techniques used in biological and clinical imaging. It explains basic concepts and imaging procedures for wide-field, confocal, multiphoton excitation, fluorescence resonance energy transfer (FRET), lifetime imaging (FLIM), spectral imaging, fluorescence recovery after photobleaching (FRAP), optical tweezers, total internal reflection, high spatial resolution atomic force microscopy (AFM), and bioluminescence imaging for gene expression. The usage of these techniques in various biological applications, including calcium, pH, membrane potential, mitochondrial signaling, protein-protein interactions under various physiological conditions, and deep tissue imaging, is clearly presented. The authors describe the approaches to selecting epifluorescence microscopy, the detectors, and the image acquisition and processing software for different biological applications. Step-by-step directions on preparing different digital formats for light microscopy images on websites are also provided.

Chemistry and Biology of Hyaluronan

Author : Hari G. Garg
Publisher : Elsevier
ISBN 13 : 0080472222
Total Pages : 625 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Chemistry and Biology of Hyaluronan by : Hari G. Garg

Download or read book Chemistry and Biology of Hyaluronan written by Hari G. Garg and published by Elsevier. This book was released on 2004-07-14 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: It was probably the French chemist Portes, who first reported in 1880 that the mucin in the vitreous body, which he named hyalomucine, behaved differently from other mucoids in cornea and cartilage. Fifty four years later Karl Meyer isolated a new polysaccharide from the vitreous, which he named hyaluronic acid. Today its official name is hyaluronan, and modern-day research on this polysaccharide continues to grow. Expertly written by leading scientists in the field, this book provides readers with a broad, yet detailed review of the chemistry of hyaluronan, and the role it plays in human biology and pathology. Twenty-seven chapters present a sequence leading from the chemistry and biochemistry of hyaluronan, followed by its role in various pathological conditions, to modified hylauronans as potential therapeutic agents and finally to the functional, structural and biological properties of hyaluronidases. Chemistry and Biology of Hyaluronan covers the many interesting facets of this fascinating molecule, and all chapters are intended to reach the wider research community. - Comprehensive look at the chemistry and biology of hyaluronans - Essential to Chemists, Biochemists and Medical researchers - Broad yet detailed review of this rapidly growing research area

Pediatric Gender Assignment

Author : Stephen A. Zderic
Publisher : Springer Science & Business Media
ISBN 13 : 9780306467592
Total Pages : 334 pages
Book Rating : 4.4/5 (675 download)

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Book Synopsis Pediatric Gender Assignment by : Stephen A. Zderic

Download or read book Pediatric Gender Assignment written by Stephen A. Zderic and published by Springer Science & Business Media. This book was released on 2003-01-31 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the proceedings from a conference that took place in Dallas in the spring of 1999 which was entitled "Pediatric Gender Assignment - A Critical Reappraisal". Some participants rightfully argued that the conference really focused on the issue of pediatric gender assignment, and that reassignment was not applied in most cases. Their comments were reflected in the title of this monograph. This multidisciplinary meeting was sponsored by a conference grant from the National Institutes of Health, and a broad inquiry into this complex topic took place from many points of view. Basic scientists offered insight into mechanisms of sexual differentiation of the gonads, physical phenotype and imprinting of the central nervous system. Endocrinologists reviewed their experience in diagnosis and management, surgeons described traditional as well as innovative approaches, and there was strong representation from the ethical and behavioral sciences. In putting together such a panel, it was essential that we identify a cast of speakers who could address their viewpoints with strong convictions, and yet not let their passions render the meeting counter productive. We were not disappointed. While many differing points of view were firmly expressed by the panelists and audience, all viewpoints were accorded the respect they deserved. The concept behind the meeting and this book really originated in 1997 shortly after Diamond and Sigmundson published their long term follow up study of the John/Joan case.

Fullerens, Graphenes and Nanotubes

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
ISBN 13 : 0128136928
Total Pages : 726 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Fullerens, Graphenes and Nanotubes by : Alexandru Mihai Grumezescu

Download or read book Fullerens, Graphenes and Nanotubes written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2018-05-28 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fullerens, Graphenes and Nanotubes: A Pharmaceutical Approach shows how carbon nanomaterials are used in the pharmaceutical industry. While there are various books on the carbonaceous nanomaterials available on the market, none approach the subject from a pharmaceutical point-of-view. In this context, the book covers different applications of carbonaceous nanomaterials. Chapters examine different types of carbon nanomaterials and explore how they are used in such areas as cancer treatments, pulse sensing and prosthetics. Readers will find this book to be a valuable reference resource for those working in the areas of carbon materials, nanomaterials and pharmaceutical science. - Explains how the unique properties of carbon-based nanomaterials allow them to be used to create effective drug delivery systems - Covers how carbon-based nanomaterials should be prepared for use in pharmaceutical applications - Discusses the relative toxicity of a range of carbon-based nanomaterials - Considers the safety of their use in different types of drugs