Lymphoproliferative Diseases: Pathogenesis, Diagnosis, Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 9400950160
Total Pages : 226 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Lymphoproliferative Diseases: Pathogenesis, Diagnosis, Therapy by : P.K. Pattengale

Download or read book Lymphoproliferative Diseases: Pathogenesis, Diagnosis, Therapy written by P.K. Pattengale and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a symposium presented at the University of Southern California, Department of Pathology and the Kenneth J. Norris Cancer Hospital and Research Institute, Los Angeles, U.S.A., November 16-17, 1984

Lymphoproliferative Diseases Pathogenesis, Diagnosis, Therapy Proceedings of a Symposium Presented at the University of Southe No

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (96 download)

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Book Synopsis Lymphoproliferative Diseases Pathogenesis, Diagnosis, Therapy Proceedings of a Symposium Presented at the University of Southe No by : University of Southern California

Download or read book Lymphoproliferative Diseases Pathogenesis, Diagnosis, Therapy Proceedings of a Symposium Presented at the University of Southe No written by University of Southern California and published by . This book was released on 1985 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Lymphoproliferative Diseases

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Publisher :
ISBN 13 :
Total Pages : 207 pages
Book Rating : 4.:/5 (658 download)

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Book Synopsis Lymphoproliferative Diseases by : University of Southern California (Los Angeles, CA). Department of Pathology

Download or read book Lymphoproliferative Diseases written by University of Southern California (Los Angeles, CA). Department of Pathology and published by . This book was released on 1985 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Cutaneous Lymphoid Proliferations

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Publisher : John Wiley & Sons
ISBN 13 : 0470053453
Total Pages : 513 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis The Cutaneous Lymphoid Proliferations by : Cynthia M. Magro

Download or read book The Cutaneous Lymphoid Proliferations written by Cynthia M. Magro and published by John Wiley & Sons. This book was released on 2007-03-31 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete reference to the latest understanding of lymphocytic infiltrates The Cutaneous Lymphoid Proliferations provides a complete, authoritative treatment of the clinical features, phenotypes, pathogenesis, histopathology, diagnosis, and treatment of lymphocytic infiltrates of the skin. Incorporating the latest findings from the fields of light microscopy, immunohistochemistry, and flow cytometry, the book brings readers up to date on the most current thinking in the field. Those readers familiar with the authors' critically acclaimed The Melanocytic Proliferations will find a similar structure and the same attention to detail and quality in this latest reference. The book starts off with a clinical atlas and introduction to the ontogeny and biology of the lymphoid system. Next, the authors explore novel molecular approaches to the diagnosis of cutaneous lymphoid proliferations and benign lymphocytic infiltrates. The remaining chapters concentrate on major inflammatory skin diseases and lymphoproliferative disorders, including chronic lymphocytic leukemia, lupus, adult T cell leukemia, and primary cutaneous Hodgkin's disease. As a reference to lymphocytic infiltrates, this book is unsurpassed. Novice and experienced practitioners alike will gain important insights into the field, including: The role of the immune system in the pathogenesis of cutaneous disease Relationships between therapeutic drugs and cutaneous eruptions Important drug reactions Hundreds of full-color, high-quality clinical and histologic photographs help readers visualize the various infiltrates and their treatments. Having this reference on hand is essential for all dermatologists, dermatopathologists, oncologists, and general pathologists who need a synthesis of the current thinking in the field.

Diagnostic and Therapeutic Advances in Hematologic Malignancies

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Publisher : Springer
ISBN 13 : 9781475782677
Total Pages : 377 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Diagnostic and Therapeutic Advances in Hematologic Malignancies by : Martin S. Tallman

Download or read book Diagnostic and Therapeutic Advances in Hematologic Malignancies written by Martin S. Tallman and published by Springer. This book was released on 2013-05-29 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is no field of medicine in which advances in therapy have been so closely linked to a better understanding of molecular medicine than in the area of hematologic malignancies. For example, recent insights into the understanding of Epstein-Barr virus have led to new treatment options for patients with posttransplant lymphoproliferative disorders, as discussed in the chapter by Dr. Richard Ambinder et al. Similarly, Drs. Slack and Gallagher discuss the explosion of recent information regarding the molecular pathogenesis of acute promyelocytic leukemia. This particular morphologic subtype of acute my­ eloid leukemia warrants separate discussion because of our increased under­ standing of the pathogenesis of leukemia, as well as the dramatic advances in outcome that have occurred with differentiation therapy provided by the vitamin A derivative aW-trans retinoic acid, as discussed in the chapter by Drs. Frankel and Powell. New approaches in the therapy of diffuse aggressive lymphomas in relationship to prognostic factors are discussed by Drs. Koc and Schenkein. Novel approaches to cutaneous T-cell lymphomas are discussed by Drs. Foss and Kuzel. Drs. Fonseca and Greipp discuss prognostic factors in myeloma, which are potentially important since they may serve to identify patients who may benefit from aggressive therapy such as bone marrow trans­ plantation, which is discussed in the chapter by Dr. David Vesole. State-of-the-art reviews are provided in the chapters on AIDS-related non- Hodgkin's lymphoma by Drs. Volm and Von Roenn, adult acute lympho­ blastic leukemia by Drs.

The Lymphoproliferative Disorders

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Publisher : CRC Press
ISBN 13 : 9780412580307
Total Pages : 416 pages
Book Rating : 4.5/5 (83 download)

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Book Synopsis The Lymphoproliferative Disorders by : J. Child

Download or read book The Lymphoproliferative Disorders written by J. Child and published by CRC Press. This book was released on 1998-09-04 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive but accessible guide to current practice and new developments in the study of lymphoproliferative disorders. The growing understanding of the cellular mechanisms and molecular pathology underlying these conditions is causing a re-evaluation of many of the basic concepts of diagnosis and treatment, leading to a vast proliferation of the primary literature - this book will help the reader to put all these changes into their proper context. The first part begins with a short overview of the normal lymphoid system, and is followed by chapters on the principles and basic techniques of laboratory diagnosis, imaging and therapy. Part Two is a systematic account of the different lymphoproliferative disorders. Each chapter concludes with a section of key reading, which includes a range of review articles and papers discussing areas of current interest. The Lymphoproliferative Disorders will be of interest to those undertaking specialist training in haematology, pathology and oncology, and will also be an invaluable reference for practising clinicians and researchers requiring a concise review of the subject.

Cutaneous T-Cell Lymphoma

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Publisher : CRC Press
ISBN 13 : 9780849321016
Total Pages : 152 pages
Book Rating : 4.3/5 (21 download)

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Book Synopsis Cutaneous T-Cell Lymphoma by : Herschel S. Zackheim

Download or read book Cutaneous T-Cell Lymphoma written by Herschel S. Zackheim and published by CRC Press. This book was released on 2004-10-28 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cutaneous T-cell lymphoma (CTCL) is a general term for many lymphomas of the skin including mycosis Fungoides and Sezary syndrome. This book presents the state of the art in CTCL epidemiology, clinical features, pathology, immunochemistry, diagnostic molecular techniques, staging and prognosis, and treatment. Edited by one of the leading experts in the disease, Cutaneous T-Cell Lymphoma: Mycosis Fungoides and Sezary Syndrome provides comprehensive coverage of the disease and presents techniques for diagnosis and state-of-the-art treatment modalities, such as ultraviolet light, steroids, and topical chemotherapeutics.

Sjogren's Syndrome

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Publisher : Academic Press
ISBN 13 : 012803632X
Total Pages : 346 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Sjogren's Syndrome by : Alessia Alunno

Download or read book Sjogren's Syndrome written by Alessia Alunno and published by Academic Press. This book was released on 2016-06-07 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sjogren's Syndrome: Novel Insights in Pathogenic, Clinical and Therapeutic Aspects provides the reader with an overview of current knowledge about Sjogren's Syndrome. The book summarizes the huge amount of literature concerning related advances in genetic background, pathogenesis, clinical picture, and therapeutic approaches. It integrates basic immunology concepts, clinical aspects, and pharmacological issues. Scientific progress has allowed us to unmask novel pathogenic mechanisms, to perform genome wide studies, and to identify clinical and serological features associated with different disease subsets and, eventually, different disease prognoses. In addition, the increasing knowledge about SS pathogenesis provides the rationale to employ targeted therapies in SS as has already occurred in rheumatoid arthritis and systemic lupus erythematosus. Discusses heterogeneity of topics and audience, from basic immunology to clinical aspects and therapeutics Provides novel lines of investigation and supports the management of patients requiring novel therapeutic approaches Presents a deeper knowledge on SS clinical management as well as on immunological aspects possibly leading to new lines of investigation Offers a bridge between the clinician and the scientist, and vice versa Provides the reader with most recent and relevant updates due to the novelty of topics

The Peripheral T-Cell Lymphomas

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Publisher : John Wiley & Sons
ISBN 13 : 1119671310
Total Pages : 434 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis The Peripheral T-Cell Lymphomas by : Owen A. O'Connor

Download or read book The Peripheral T-Cell Lymphomas written by Owen A. O'Connor and published by John Wiley & Sons. This book was released on 2021-06-01 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE PERIPHERAL T-CELL LYMPHOMAS Provides a comprehensive look at Peripheral T-Cell lymphomas, including the group’s unique geographic distribution, underlying genetics, and novel treatments Peripheral T-Cell lymphomas (PTCL) are a diverse group of lymphoid malignancies that develop from mature T cells and natural killer (NK) cells. PTCL represent 10-15% of all cases of non-Hodgkin lymphoma in the US, and up to 20-25% of cases in South America, Asia, and other regions around the world. The role of different etiologic factors and the variation of geographic distribution makes PTCL one of the most difficult types of cancer to understand and treat. For the first time in a single volume, The Peripheral T-Cell Lymphomas presents a comprehensive survey of this complex and rare group of blood cancers. Featuring contributions from an international team of leading authorities in the various aspects of PTCL, this authoritative text covers biology, epidemiology, classification, approved and emerging drugs, molecular genetics, and more. Detailed clinical chapters address diagnosis, prognosis, and treatment of each of the major PTCL subtypes identified in the 2018 WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. This much-needed resource: Covers the biological basis, epidemiology, classification, and treatment of PTCL Discusses the future of the field, including global collaboration efforts and novel approaches to PCTL Explores the role of biologics in PTCL and autologous and allogeneic stem-cell transplantation Offers new insights on molecular pathogenesis, innovative therapeutics, and novel drug combinations Features contributions from the Chairs The T-Cell Lymphoma Forum: the world’s largest meeting focused on PTCL Reflecting the unique epidemiology and genetic diversity of the PTCL, The Peripheral T-Cell Lymphomas is an indispensable source of data, insight, and references for the medical community, particularly oncologists and hematologists in both training and practice.

Aplastic Anemia

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Publisher : Cambridge University Press
ISBN 13 : 9780521641012
Total Pages : 410 pages
Book Rating : 4.6/5 (41 download)

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Book Synopsis Aplastic Anemia by : Hubert Schrezenmeier

Download or read book Aplastic Anemia written by Hubert Schrezenmeier and published by Cambridge University Press. This book was released on 2000 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive and up-to-date clinical reference, with an emphasis on treatment.

Lymphoproliferative Diseases

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Publisher : Springer
ISBN 13 : 9789401068178
Total Pages : 232 pages
Book Rating : 4.0/5 (681 download)

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Book Synopsis Lymphoproliferative Diseases by : D.B. Jones

Download or read book Lymphoproliferative Diseases written by D.B. Jones and published by Springer. This book was released on 2011-10-06 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments in the field of cellular pathology and molecular biology have had a major impact on our ability to diagnose lymphoreticular disease and on our understanding of many of the disease processes which contribute to lymphoreticular pathology. Twenty years ago, the immunological analysis of lymphoid proliferations was in its infancy. The techniques available, such as sheep red blood cell rosetting and immune adherence to frozen sections, now appear unbelievably crude when compared with our ability to accurately phenotype lymphocytes in suspension, in frozen section and, more recently, in formalin-fixed, paraffin-embedded tissue biopsies. Four international work shops have also standardized the nomenclature for the wide range of lineage restricted and lineage-related monoclonal antibodies available, and have provided a basis for the sophisticated phenotypic analysis of lymphoid neoplasms in even the smallest routine laboratories. Our concepts relating to the pathogenesis of a number of human lymphomas have also changed substantially, and this has been aided by the development of systems for the classification of human lymphoma which are firmly based in our knowledge of the differentiation and biological behaviour of normal lymphoreticular cells. In this monograph, we present contributions from many authors examining both leukaemia and lymphoma from an immunological perspec tive. It is our hope that some of these contributions will be of practical value in the laboratory investigation and diagnosis of lymphoreticular disease. Other contributions record our conceptual understanding of the histogenesis and pathogenesis of human lymphoma.

Pediatric Lymphomas

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Publisher : Springer Science & Business Media
ISBN 13 : 354068753X
Total Pages : 296 pages
Book Rating : 4.5/5 (46 download)

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Book Synopsis Pediatric Lymphomas by : Howard J. Weinstein

Download or read book Pediatric Lymphomas written by Howard J. Weinstein and published by Springer Science & Business Media. This book was released on 2007-01-20 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive textbook of Hodgkin's and non-Hodgkin's lymphomas written by leaders in the field of childhood lymphomas. It includes clinical, pathologic and molecular biology of each subtype of lymphoma. The pathology chapters are comprehensive and include excellent photographs. The book is at the level of subspecialists in pediatric hematology and oncology, radiation oncology, pediatric surgery and hematopathology.

Essentials of Surgical Pediatric Pathology

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Publisher : Cambridge University Press
ISBN 13 : 1316124150
Total Pages : 1225 pages
Book Rating : 4.3/5 (161 download)

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Book Synopsis Essentials of Surgical Pediatric Pathology by : Marta C. Cohen

Download or read book Essentials of Surgical Pediatric Pathology written by Marta C. Cohen and published by Cambridge University Press. This book was released on 2015-02-05 with total page 1225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Surgical Pediatric Pathology is a clear and practical yet comprehensive guide for trainee pediatric pathologists and non-pediatric pathologists. Each chapter corresponds to one of the main subspecialties, such as dermatopathology, head and neck pathology, and system pathology. Practical guidance is given on handling pediatric specimens and the authors highlight the ways in which common conditions present differently in adults and children. Other chapters cover conditions typical of childhood, including soft tissue tumors and blue round cell tumors. The chapters begin with a brief clinical presentation, followed by a clear macroscopical and histological description of the principal pathologies seen in children. Up-to-date genetic and immunohistochemical information is provided, and the book includes hundreds of high-quality color images. Written and edited by leading international experts in the field, this is an essential resource for trainee pediatric pathologists, as well as general pathologists who may encounter pediatric cases.

Diffuse Cystic Lung Diseases

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Publisher : Springer Nature
ISBN 13 : 3030633659
Total Pages : 384 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Diffuse Cystic Lung Diseases by : Nishant Gupta

Download or read book Diffuse Cystic Lung Diseases written by Nishant Gupta and published by Springer Nature. This book was released on 2021-01-28 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive reference on diffuse cystic lung diseases (DCLDs). DCLDs are a group of pathophysiologically heterogenous processes that are characterized by the presence of multiple spherical or irregularly shaped, thin-walled, air-filled spaces within the pulmonary parenchyma. In recent years, tremendous advancements have been made in these diseases leading to improved understanding of the underlying pathophysiology, and improved outcomes with targeted therapies. The authors, who are leading experts in the field, delineate DCLDs as a separate category distinct from other interstitial lung diseases, and have created this textbook specifically dedicated to this disease group. This book begins with a chapter introducing the definition and classification of DCLDs. Subsequent chapters address the pathogenic mechanisms underlying pulmonary cyst formation and provide a detailed overview of the radiological and pathological features of DCLDs. The common as well as uncommon causes of DCLDs are comprehensively reviewed in individual chapters, as are the varied clinical presentations and extrapulmonary manifestations, and approaches to management and treatment. The book culminates in a final chapter that presents a practical algorithmic approach to diagnosis that progresses from least invasive to most invasive approaches. This textbook provides a one-stop, comprehensive and integrated, clinical, radiologic, and pathologic overview of DCLDs that will be as useful to the practicing clinician as it is to the clinical investigator.

Brain Oncology Biology, diagnosis and therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 9400933479
Total Pages : 428 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Brain Oncology Biology, diagnosis and therapy by : M. Chatel

Download or read book Brain Oncology Biology, diagnosis and therapy written by M. Chatel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Meeting on Brain Oncology in Rennes was organised in honor of Jean Pecker, to pay tribute to his contribution to the development of neurological sciences and to take stock of the current state of knowledge on brain tumors, a domain in which the role of neurosurgery has been and will continue to be primordial. During the two-day conference, the major themes of brain oncology studies, both fundamental and clinical, were examined: oncogenesis, tumoral markers and immunology, metabolic and diagnosis imaging, prognostic factors and therapeutic strategies. The large number and high quality of participations resulted in a genuinely synthetic view of current advances in research, of which this book presents the essentials. We have attempted both to preserve the richness of scientific exchanges which occurred and to publish a great many oral and poster communications. The book respects the organization of conference sessions, and thus reflects the importance accorded to glial tumor studies. This may seem disproportionate given their frequency of occurrence in proportion to total numbers of intracranial tumor processes, but their gravity and quasi-total resistance to current therapeutic methods are ample justification. Moreover, this is the domain in which hopes of progress are beginning to appear, and it is becoming possible to envisage treatment based on recently established fundamental knowledge.

A Historical Perspective on Evidence-Based Immunology

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Publisher : Newnes
ISBN 13 : 0123983754
Total Pages : 396 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis A Historical Perspective on Evidence-Based Immunology by : Edward J. Moticka

Download or read book A Historical Perspective on Evidence-Based Immunology written by Edward J. Moticka and published by Newnes. This book was released on 2015-11-25 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology Presents concepts such as the division of lymphocytes into functionally different populations in their historical context Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells

Leukemias

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Publisher : John Wiley & Sons
ISBN 13 : 1444347810
Total Pages : 460 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Leukemias by : Stefan Faderl

Download or read book Leukemias written by Stefan Faderl and published by John Wiley & Sons. This book was released on 2011-09-14 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by experts from one of the world’s largest leukemia centers, this book provides information on the biology of the variety of leukemic disorders, up-to-date diagnostic testing and many new developments in therapy. Chapters covering new treatments present an outlook for the future and explain the rationale for ongoing clinical trials. Topics include: Targeted therapy, e.g. tyrosine kinase inhibitors (Flt3, Aurora kinase inhibitors, kit inhibitors, BCR-ABL inhibitors) Ras inhibitors Epigenetic therapy (hypomethylaters and histone deacetylase inhibitors) Lenalidomide analogs New chemotherapy drugs, e.g. clofarabine, cloretazine, sapacitabine, forodesine Combinations of chemotherapy with kinase inhibitors (e.g. ALL induction protocols in combination with dasatinib or imatinib) New monoclonal antibodies (lumiliximab, humaxCD20, anti-CD40) Thrombopoietic agents Leukemias: Principles and Practice of Therapy Includes practical information to guide you in challenging situations, such as treatment of elderly patients, pregnancy, relapsed and refractory disease Incorporates chapters on supportive care and pharmacologic information about the most frequently used drugs in this area