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Lymphatic Metastasis And Sentinel Lymphonodectomy
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Book Synopsis Lymphatic Metastasis and Sentinel Lymphonodectomy by : P.M. Schlag
Download or read book Lymphatic Metastasis and Sentinel Lymphonodectomy written by P.M. Schlag and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metastases determine malignancy. The main attention so far has been focused upon organ metastases. The molecular mechanisms thereof, while far from being totally elucidated, are increasingly well understood. Modern diagnostic tools now enable detection and precise localization of small lesions. In contrast, our knowl edge and diagnostic capabilities regarding metastatic spread to the'lymphatic system are rather limited. However, there have re cently been a number of interesting advances. It is the aim of this volume to submit these developments to detailed analysis. The therapeutic relevance of enhanced sensitivity in detection of lymph node metastases has to be considered in the light of in creased morbidity versus eventual prognostic improvements by modification of therapy. An interesting concept which might im prove diagnostic accuracy while reducing operative morbidity is the "sentinel node" technique. Surgical standards are lacking, however, and many fundamental questions pertaining to precise lymphatic mapping remain unanswered. Whether the sentinel node concept is of general relevance or whether it is applicable in only a few organs remains to be determined. This book offers intensive discussion of the concept from methodological and tu mor biological viewpoints. World-renowned experts with long term involvement in related basic and clinical research provide the reader with a broad survey of actual knowledge together with a critical appraisal of recent and future developments. We sincerely hope this book succeeds in providing an outlook as a reference for all clinicians on future prospects and serving and researchers in this extremely important field.
Book Synopsis Lymphatic metastasis and sentinel lymphonodectomy by : Peter M. Schlag
Download or read book Lymphatic metastasis and sentinel lymphonodectomy written by Peter M. Schlag and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Sentinel Lymph Node Concept by : Alfred Schauer
Download or read book The Sentinel Lymph Node Concept written by Alfred Schauer and published by Springer Science & Business Media. This book was released on 2005-10-28 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: The practical application of the sentinel node concept is evaluated in this book. The concept is analyzed for breast cancer, malignant melanoma, tumors of the face, oropharynx, lung, gastrointestinal and urogenital tract. The first part of the book describes the function and use of the nuclear medicine equipment, the tracers used, colloid solutions and modern developments in histological and immunohistochemical lymph node investigations, as well as possible pitfalls. In the second part, specific tumor-related problems are described.
Book Synopsis Atlas of Lymphatic System in Cancer by : Shamil Gantsev
Download or read book Atlas of Lymphatic System in Cancer written by Shamil Gantsev and published by Springer Nature. This book was released on 2020-04-01 with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas contains a large number of original photographs illustrating the anatomy, research methods, and structural features of the structure of the lymphatic apparatus in oncological diseases. The tissue complexes of the axillary region have been studied in detail. The lymphatic maps of the axillary region in cancer are presented, including those with manifestations of lymphangiogenesis; newly formed lymph nodes formed as a result of neolymphogenesis are also considered. Atlas of Lymphatic System in Cancer: Sentinel Lymph Node, Lymphangiogenesis and Neolymphogenesis is intended for oncologists, anatomists, morphologists and doctors of other specialties. The book is the result of ten years of research. The applied technology of ultrasonic isolation of anatomical structures made it possible to take a fresh look at the lymphatic apparatus in cancer and describe the phenomenon of neolymphogenesis.
Book Synopsis Cancer Metastasis and the Lymphovascular System: by : Stanley P. L. Leong
Download or read book Cancer Metastasis and the Lymphovascular System: written by Stanley P. L. Leong and published by Springer Science & Business Media. This book was released on 2007-09-05 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book details the anatomy and physiology of the lymphovascular system as well as describes the mechanisms of metastasis. It provides readers with an understanding of immune responses of draining lymph nodes against cancer. Coverage also explains the rationale of adopting molecular therapeutics against growth factor receptors, apoptotic factors, signaling pathways and angiogenesis.
Book Synopsis Sentinel Lymph Node Biopsy by : Hiram S. Cody
Download or read book Sentinel Lymph Node Biopsy written by Hiram S. Cody and published by CRC Press. This book was released on 2001-11-08 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: An intuitive, ingenious and powerful technique, sentinel lymph node biopsy has entered clinical practice with astonishing rapidity and now represents a new standard of care for melanoma and breast cancer patients, while showing great promise for the treatment of urologic, colorectal, gynecologic, and head and neck cancers. This text, written by international experts in the technique, provides a clear and comprehensive guide, presenting a detailed overview and discussing the various mapping techniques available and how these are applied in a number of leading institutions. This essential resource for surgical onocologists, pathologists, and specialists in nuclear medicine will also provide key information for those planning to start a sentinel lymph node program.
Book Synopsis Atlas of Selective Sentinel Lymphadenectomy for Melanoma, Breast Cancer and Colon Cancer by : Stanley P. L. Leong
Download or read book Atlas of Selective Sentinel Lymphadenectomy for Melanoma, Breast Cancer and Colon Cancer written by Stanley P. L. Leong and published by Springer Science & Business Media. This book was released on 2006-04-18 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atlas of Selective Lymphadenectomy for Melanoma, Breast Cancer and Colon Cancer emphasizes a multidisciplinary approach combining the experiences of a nuclear medicine physician, surgeon, and pathologist. This is an important reference also for researchers and clinicians who want to become familiar with sentinel lymph node mapping. The underlying thesis in solid tumor biology is that metastasis in general starts in an orderly progression with lymphatic spread first to the sentinel lymph node (SLN) in the nearest lymph node basin. Therefore, the logical approach is to harvest that specific SLN for thorough analysis.
Book Synopsis Atlas of Lymphoscintigraphy and Sentinel Node Mapping by : Giuliano Mariani
Download or read book Atlas of Lymphoscintigraphy and Sentinel Node Mapping written by Giuliano Mariani and published by Springer Nature. This book was released on 2020-07-29 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main goal of the second edition of this book is to update the content on the rapidly growing field of lymphoscintigraphy, a radionuclide-based imaging procedure that provides information on the functional status of the lymphatic system. Although the technique was originally introduced to identify the cause of peripheral edema (i.e., blockage of the venous or lymphatic circulation), more recent and widespread applications include radioguided biopsy of the sentinel lymph node in patients with solid cancers. This procedure is crucial for the adequate planning of oncologic surgery in a growing number of cancers, most notably breast cancer, cutaneous melanoma, head and neck cancers, penile cancer, and cervical cancer. The book focuses on the latest advances in lymphoscintigraphy techniques, including both novel tracers recently approved for clinical use (especially in the field of sentinel lymph node mapping) and the expanding role of hybrid imaging with SPECT/CT – and in sentinel node detection using hybrid tracers (radiolabeled and fluorescent) for dual-signature guidance. Each chapter addresses the clinical application of lymphoscintigraphy in different anatomic areas or disease conditions. After an introductory section concerning the pathophysiology of the specific site/disease, the clinical relevance and impact of lymphoscintigraphy is demonstrated by a collection of richly illustrated teaching cases describing the lymphoscintigraphic patterns most commonly observed, as well as anatomic variants and technical pitfalls. Emphasis is placed on tomographic multimodality imaging. The book gathers contributions by experts in nuclear oncology, who have revised their chapters by updating the didactic material and adding clinical cases. Regarding sentinel lymph node biopsy in particular, a major distinction of this text is the incorporation of the staging guidelines of the American Joint Committee on Cancer (8th edition) into the didactic material.
Book Synopsis The Sentinel Node in Surgical Oncology by : Mohammad R.S. Keshtgar
Download or read book The Sentinel Node in Surgical Oncology written by Mohammad R.S. Keshtgar and published by Springer. This book was released on 2014-10-03 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume an account is given of the technologies relevant to the detection of sentinel lymph nodes in the context of surgical oncology. This is a rapidly and evolving field, and the clinical applications discussed in this volume are exciting and important. A multidisciplinary team was assembled to discuss this subject in the light of direct experience gained by each of the groups in the previous 12 months. Clinical case material is presented and the methodology of sentinel lymph node imaging and detection is discussed in detail. The authors have assembled in a single volume a significant amount of personal data and a comprehensive literature review which will serve as a single reference and teaching source for all those interested in this critical technique relevant to the management of large numbers of patients in surgical oncology.
Book Synopsis Selective Sentinel Lymphadenectomy for Human Solid Cancer by : Stanley P. L. Leong
Download or read book Selective Sentinel Lymphadenectomy for Human Solid Cancer written by Stanley P. L. Leong and published by Springer Science & Business Media. This book was released on 2006-06-20 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: First book to apply the concept of SSL to the majority of human cancers Revolutionary new concept that might significantly transform surgical cancer treatment Focuses on cancer metastasis and explores the biological frontier of micro metastasis Includes illustrations by experts in the field on how to successfully perform SSL
Book Synopsis Lymph Node Metastasis in Gastrointestinal Cancer by : Shoji Natsugoe
Download or read book Lymph Node Metastasis in Gastrointestinal Cancer written by Shoji Natsugoe and published by Springer. This book was released on 2019-01-23 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the most comprehensive and up-to-date knowledge of lymph node micrometastasis (LMM) and sentinel node navigation surgery (SNNS) in gastrointestinal cancers. Lymph node metastasis is a critically important prognostic factor in gastrointestinal tract cancers such as tumors of the esophagus, stomach, and colorectum. An understanding of the basic aspects of lymphatics and lymph nodes, including anatomy, histology, physiology, immunology, and molecular biology, is fundamental for physicians who are involved in cancer treatment. Furthermore, owing to the development of molecular and biological methodology, the precise recognition of LMM and its clinical significance have been clarified recently. At the same time, SNNS has actually been anticipated in treatment of breast tumors, and it is now being introduced in gastrointestinal tract cancer. For the application of SNNS, the detection of lymph node metastasis including LMM is extremely significant, because the presence of LMM determines the direction for surgery and chemo and/or radiation therapy. With these considerations in mind, the expert contributors to this book review basic and clinical approaches for LMM and SNNS including methodology for gastrointestinal cancers. Thus this volume benefits not only surgeons who treat gastrointestinal cancers but also clinical oncologists and medical scientists such as physiologists and pathologists.
Book Synopsis Sentinel Lymph Node Biopsy Has No Benefit for Patients with Primary Cutaneous Melanoma by : Neil Medalie
Download or read book Sentinel Lymph Node Biopsy Has No Benefit for Patients with Primary Cutaneous Melanoma written by Neil Medalie and published by . This book was released on 2004 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Lymph Node Metastasis in Gastrointestinal Cancer by : Shoji Natsugoe
Download or read book Lymph Node Metastasis in Gastrointestinal Cancer written by Shoji Natsugoe and published by . This book was released on 2019 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the most comprehensive and up-to-date knowledge of lymph node micrometastasis (LMM) and sentinel node navigation surgery (SNNS) in gastrointestinal cancers. Lymph node metastasis is a critically important prognostic factor in gastrointestinal tract cancers such as tumors of the esophagus, stomach, and colorectum. An understanding of the basic aspects of lymphatics and lymph nodes, including anatomy, histology, physiology, immunology, and molecular biology, is fundamental for physicians who are involved in cancer treatment. Furthermore, owing to the development of molecular and biological methodology, the precise recognition of LMM and its clinical significance have been clarified recently. At the same time, SNNS has actually been anticipated in treatment of breast tumors, and it is now being introduced in gastrointestinal tract cancer. For the application of SNNS, the detection of lymph node metastasis including LMM is extremely significant, because the presence of LMM determines the direction for surgery and chemo and/or radiation therapy. With these considerations in mind, the expert contributors to this book review basic and clinical approaches for LMM and SNNS including methodology for gastrointestinal cancers. Thus this volume benefits not only surgeons who treat gastrointestinal cancers but also clinical oncologists and medical scientists such as physiologists and pathologists.
Book Synopsis Lymphatic Drainage of the Skin and Breast: Locating the Sentinel Nodes by : Robert Howman-Giles
Download or read book Lymphatic Drainage of the Skin and Breast: Locating the Sentinel Nodes written by Robert Howman-Giles and published by CRC Press. This book was released on 1999-06-11 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting many previously unknown patterns of lymph drainage and based on more than 2000 studies of melanoma patients, this book is a valuable addition to the topic of lymphatic mapping and sentinel node biopsy which is of such considerable interest in surgical oncology. The authors' vast experience and their insights in applying this technique to patients with melanoma will be invaluable to any surgical oncology team contemplating introducing this approach to management of their patients. A section on lymphatic drainage patterns of the breast is also included, based on 90 studies of breast cancer patients. The new lymphatic drainage pathways described will also be of interest to other surgeons and anatomists.
Book Synopsis Sentinel Lymph Node Biopsy Using Indigocyanine Green Fluorescence in Uterine Cancer by : Wieland Sell
Download or read book Sentinel Lymph Node Biopsy Using Indigocyanine Green Fluorescence in Uterine Cancer written by Wieland Sell and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: IntroductionIn endometrial cancer, societies such as the Society of Gynecological Oncology and National Comprehensive Cancer Network recommend sentinel lymph node biopsy using indigocyanine green (ICG-SLNB) as a reasonable staging strategy. According to a meta-analysis, ICG as a tracer injected into the cervix yields higher detection rates than other tracers or other injection sites. Compared to standard systematic lymphonodectomy (LND), ICG-SLNB has lower morbidity, allows detection of lymph nodes in atypical locations, such as the presacral and parametrial areas, and allows for microstaging of lymph nodes assessed by systemic lymphadenectomy.Material and MethodsWe did a retrospective analysis of 45 patients who had ICG-SLNB for uterine cancer using conventional laparoscopy or robotic surgery from 2012 to 2019. ICG was injected into the cervix, 1ml subepithelial and 1ml into the stroma at both 3 and 9 ou2019clock. Two different optical systems were used: Karl Storz Opal-1 NIR/ICG (n=10) and Novadaq Pinpoint (n=35). Pathological ultrastaging was done by sampling the SLN at 2mm intervals with additional cytokeratin staining. Number of technical failures, detected sentinel nodes and their location was assessed. Technical failures were defined as no lymph node staining or only unilateral pelvic staining. We also compared sites of lymph node metastasis using ICG-SLNB to 10 endometrial cancer patients having metastatic lymph nodes assessed by systematic lymphadenectomy.ResultsA total of 353 lymph nodes were detected, of which 22 (6%) were metastatic. Six percent of SLN were found in atypical locations. Seven women (16%) had SLN in atypical locations (3 in parametrium only and 4 in the presacral only).DiscussionThe imaging device has an impact on the number of sentinel nodes detected and the technical failure rate. Sixteen percent of patients had SLN in atypical locations, however none had metastatic disease. The pattern of nodal spread was similar in both ICG-SLN and systematic LND, which is reassuring.
Book Synopsis Radioguided Surgery by : Giuliano Mariani
Download or read book Radioguided Surgery written by Giuliano Mariani and published by Springer Science & Business Media. This book was released on 2010-05-10 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multidisciplinary textbook is designed to be the standard on the subject and is geared for use by physicians who are involved in the care and/or diagnosis of cancer patients. Comprehensive coverage is provided on all aspects of radioguided surgery. Practical information is readily accessible and throughout there is an emphasis on improved decision making. Tables present the indications, performance, and interpretation of procedures at a glance. A wealth of illustrations, including a full-color insert, enhances the application of new concepts.
Book Synopsis Nuclear Oncology by : Cumali Aktolun
Download or read book Nuclear Oncology written by Cumali Aktolun and published by Lippincott Williams & Wilkins. This book was released on 2014-09-04 with total page 1964 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear Oncology a contemporary narrative of the role of nuclear medicine in oncology with an emphasis on SPECT/CT and PET/CT with additional comments when appropriate on the potential application of PET/MR and to a lesser degree, targeted radionuclide therapy. This book focuses on the use of radionuclides in the diagnosis and treatment of malignant diseases. It describes relevant approved and investigational clinical applications, instrumentation & technology, chemistry and practical clinical issues in nuclear oncology. The basic science and current research topics of nuclear oncology are addressed in separate chapters. Nuclear medicine has become an essential component to all phases of the management of the patient with a malignant tumor and in some cases, even benign neoplasms. The standard of practice for many tumors requires PET/CT imaging at various stages of diagnosis and management. In addition to clinical applications, ongoing investigational efforts, which more and more involve multi-institutional protocols, are also presented. Features: • Focuses on the use of radionuclides in the diagnosis and treatment of malignant diseases • Emphasizes SPECT/CT and PET/CT with additional emphasis on the potential application of PET/MR • Describes relevant approved and investigational clinical applications, instrumentation & technology, chemistry and practical clinical issues in nuclear oncology
