Lost In Translation: Barriers To Incentives For Translational Research In Medical Sciences

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Author :
Publisher : World Scientific
ISBN 13 : 9814489085
Total Pages : 766 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Lost In Translation: Barriers To Incentives For Translational Research In Medical Sciences by : Rakesh Srivastava

Download or read book Lost In Translation: Barriers To Incentives For Translational Research In Medical Sciences written by Rakesh Srivastava and published by World Scientific. This book was released on 2014-03-14 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is all about the definition and finding ways to prioritize and accelerate translation research in biomedical sciences and rapidly turning new knowledge into first-in-human studies. It represents an effort to bring together scientists active in various areas of translational research to share science and, hopefully, generate new ideas and potential collaborations. The book provides a comprehensive overview of translational work that includes significant discoveries and pioneering contributions, e.g., in immunology, gene therapy, stem cells and population sciences. It may be used as an advanced textbook by graduate students and even ambitious undergraduates in biomedical sciences. It is also suitable for non-experts, i.e. medical doctors, who wish to have an overview of some of the fundamental models in translational research.Managing the translational enterprise remains a work in progress. The world is changing rapidly, and the scientific world needs to seek new ways to ensure that discoveries get translated for patients efficiently and as quickly as possible. In addition, everyone expects the investment in biomedical research should pay dividends through effective therapeutic solutions. This unique project provides a broad collaborative approach of the international scientific team to present its view and opinion how to cross barriers to incentives for translational research in medical sciences.Contributing to the book is an international team of prominent co-authors. The book consists of unique and widely treated topics, and includes new hypotheses, data and analyses.

Lost in Translation

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Author :
Publisher : World Scientific
ISBN 13 : 9814489077
Total Pages : 766 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Lost in Translation by : Rakesh K. Srivastava

Download or read book Lost in Translation written by Rakesh K. Srivastava and published by World Scientific. This book was released on 2014 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is all about the definition and finding ways to prioritize and accelerate translation research in biomedical sciences and rapidly turning new knowledge into first-in-human studies. It represents an effort to bring together scientists active in various areas of translational research to share science and, hopefully, generate new ideas and potential collaborations. The book provides a comprehensive overview of translational work that includes significant discoveries and pioneering contributions, e.g., in immunology, gene therapy, stem cells and population sciences. It may be used as an advanced textbook by graduate students and even ambitious undergraduates in biomedical sciences. It is also suitable for non-experts, i.e. medical doctors, who wish to have an overview of some of the fundamental models in translational research. Managing the translational enterprise remains a work in progress. The world is changing rapidly, and the scientific world needs to seek new ways to ensure that discoveries get translated for patients efficiently and as quickly as possible. In addition, everyone expects the investment in biomedical research should pay dividends through effective therapeutic solutions. This unique project provides a broad collaborative approach of the international scientific team to present its view and opinion how to cross barriers to incentives for translational research in medical sciences. Contributing to the book is an international team of prominent co-authors. The book consists of unique and widely treated topics, and includes new hypotheses, data and analyses. Sample Chapter(s). Foreword (41 KB). Chapter 1: Translational Research: Lost in Complexity (305 KB). Contents: Barriers to Incentives for Translational Research; Integrating Emerging Science into Clinical Practice; Organization, Prioritization, Review and Funding for the Translational Research; Translational Sciences in Cancer Research; Translational Science in Infectious Diseases; Translation Research in Endocrinology and Nutrition; Translation Research and Neuroscience; Stem Cells and Translation Research; The Role of Translational Research in Public Health and Behavioral Sciences; Translational Epidemiology, Biostatistics and Informatics; Translational Research Outcomes and Resources. Readership: Graduate students and researchers in cancer research, pharmacology/drug discovery/pharmaceuticals, immunology, infectious diseases and public health.

The Biology Book

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Publisher : Union Square + ORM
ISBN 13 : 1454915331
Total Pages : 1050 pages
Book Rating : 4.4/5 (549 download)

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Book Synopsis The Biology Book by : Michael C. Gerald

Download or read book The Biology Book written by Michael C. Gerald and published by Union Square + ORM. This book was released on 2015-01-06 with total page 1050 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This beautifully illustrated book covers four billion years of biology history . . . appealing for readers with little to no background in science.” —Library Journal From the emergence of life, to Leewenhoeks microscopic world, to GMO crops, The Biology Book presents 250 landmarks in the most widely studied scientific field. Brief, engaging, and colorfully illustrated synopses introduce readers to every major subdiscipline, including cell theory, genetics, evolution, physiology, thermodynamics, molecular biology, and ecology. With information on such varied topics as paleontology, pheromones, nature vs. nurture, DNA fingerprinting, bioenergetics, and so much more, this lively collection will engage everyone who studies and appreciates the life sciences.

Enabling America

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Publisher : National Academies Press
ISBN 13 : 0309174619
Total Pages : 422 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Enabling America by : Institute of Medicine

Download or read book Enabling America written by Institute of Medicine and published by National Academies Press. This book was released on 1997-11-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most recent high-profile advocate for Americans with disabilities, actor Christopher Reeve, has highlighted for the public the economic and social costs of disability and the importance of rehabilitation. Enabling America is a major analysis of the field of rehabilitation science and engineering. The book explains how to achieve recognition for this evolving field of study, how to set priorities, and how to improve the organization and administration of the numerous federal research programs in this area. The committee introduces the "enabling-disability process" model, which enhances the concepts of disability and rehabilitation, and reviews what is known and what research priorities are emerging in the areas of: Pathology and impairment, including differences between children and adults. Functional limitationsâ€"in a person's ability to eat or walk, for example. Disability as the interaction between a person's pathologies, impairments, and functional limitations and the surrounding physical and social environments. This landmark volume will be of special interest to anyone involved in rehabilitation science and engineering: federal policymakers, rehabilitation practitioners and administrators, researchers, and advocates for persons with disabilities.

An Introduction to Using Theory in Social Work Practice

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Author :
Publisher : Routledge
ISBN 13 : 1317929543
Total Pages : 264 pages
Book Rating : 4.3/5 (179 download)

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Book Synopsis An Introduction to Using Theory in Social Work Practice by : James A. Forte

Download or read book An Introduction to Using Theory in Social Work Practice written by James A. Forte and published by Routledge. This book was released on 2014-01-21 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Using Theory in Social Work Practice equips the reader to use fourteen key social work theories to guide each phase of the planned change process, from engagement through to evaluation. Suitable for a generalist approach, this book illustrates the value of applying theory to practice in a variety of social work roles, across diverse fields and facing assorted challenges. The first section provides a practical foundation for beginning to use theory in your social work practice. Section two looks at how you can translate and integrate fourteen theories commonly found in social work across each phase of the planned change process. The theories discussed are: behavioural, interpretive anthropology, psychodynamic, evolutionary biology, cognitive, symbolic interactionism, strengths, social constructionism exchange economics, role, ecological, critical, feminist, and systems theory. The final section addresses some key issues for real life social work practice, including common barriers to using theory in practice, the potential for multi-professional communication and theory-sharing, and developing an integrative theoretical model for your own personal practice. Linking to core competencies identified by the Council of Social Work Education, this text supports social work students and practitioners in developing vital skills, including critical thinking, applying theory and the effective use of the planned change process.

Oxford Textbook of Global Public Health

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Publisher : Oxford University Press
ISBN 13 : 019881013X
Total Pages : 1717 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis Oxford Textbook of Global Public Health by : Roger Detels

Download or read book Oxford Textbook of Global Public Health written by Roger Detels and published by Oxford University Press. This book was released on 2017 with total page 1717 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sixth edition of the hugely successful, internationally recognised textbook on global public health and epidemiology, with 3 volumes comprehensively covering the scope, methods, and practice of the discipline

Management and Leadership for Nurse Administrators

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Publisher : Jones & Bartlett Learning
ISBN 13 : 1284282562
Total Pages : 426 pages
Book Rating : 4.2/5 (842 download)

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Book Synopsis Management and Leadership for Nurse Administrators by : Linda A. Roussel

Download or read book Management and Leadership for Nurse Administrators written by Linda A. Roussel and published by Jones & Bartlett Learning. This book was released on 2022-08-05 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: To succeed as leaders of a diverse, multigenerational workforce, nurse managers and executives need to have both traditional management skills and a contemporary, creative mindset. Management and Leadership for Nurse Administrators, Ninth Edition provides a comprehensive overview of key management and administrative concepts critical to leading modern healthcare organizations and ensuring patient safety and quality care. With this text, students will be prepared to lead a workplace that is rapidly evolving due to technology, culture, and changes in the U.S. healthcare system. The Ninth Edition features a new Introduction with a review of the current trends and patterns in nursing leadership, along with expanded discussions of translational science focused on implementation and dissemination, workforce well-being, resiliency, work-life balance, healthy work environments, and more timely topics.

Transforming Clinical Research in the United States

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Publisher : National Academies Press
ISBN 13 : 0309163358
Total Pages : 151 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Transforming Clinical Research in the United States by : Institute of Medicine

Download or read book Transforming Clinical Research in the United States written by Institute of Medicine and published by National Academies Press. This book was released on 2010-10-22 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.

The Role of NIH in Drug Development Innovation and Its Impact on Patient Access

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Author :
Publisher : National Academies Press
ISBN 13 : 0309498511
Total Pages : 103 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis The Role of NIH in Drug Development Innovation and Its Impact on Patient Access by : National Academies of Sciences, Engineering, and Medicine

Download or read book The Role of NIH in Drug Development Innovation and Its Impact on Patient Access written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-01-27 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: To explore the role of the National Institutes of Health (NIH) in innovative drug development and its impact on patient access, the Board on Health Care Services and the Board on Health Sciences Policy of the National Academies jointly hosted a public workshop on July 24â€"25, 2019, in Washington, DC. Workshop speakers and participants discussed the ways in which federal investments in biomedical research are translated into innovative therapies and considered approaches to ensure that the public has affordable access to the resulting new drugs. This publication summarizes the presentations and discussions from the workshop.

The Learning Healthcare System

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Publisher : National Academies Press
ISBN 13 : 0309133939
Total Pages : 374 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Learning Healthcare System by : Institute of Medicine

Download or read book The Learning Healthcare System written by Institute of Medicine and published by National Academies Press. This book was released on 2007-06-01 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: As our nation enters a new era of medical science that offers the real prospect of personalized health care, we will be confronted by an increasingly complex array of health care options and decisions. The Learning Healthcare System considers how health care is structured to develop and to apply evidence-from health profession training and infrastructure development to advances in research methodology, patient engagement, payment schemes, and measurement-and highlights opportunities for the creation of a sustainable learning health care system that gets the right care to people when they need it and then captures the results for improvement. This book will be of primary interest to hospital and insurance industry administrators, health care providers, those who train and educate health workers, researchers, and policymakers. The Learning Healthcare System is the first in a series that will focus on issues important to improving the development and application of evidence in health care decision making. The Roundtable on Evidence-Based Medicine serves as a neutral venue for cooperative work among key stakeholders on several dimensions: to help transform the availability and use of the best evidence for the collaborative health care choices of each patient and provider; to drive the process of discovery as a natural outgrowth of patient care; and, ultimately, to ensure innovation, quality, safety, and value in health care.

Strengthening Forensic Science in the United States

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Publisher : National Academies Press
ISBN 13 : 0309142393
Total Pages : 348 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Strengthening Forensic Science in the United States by : National Research Council

Download or read book Strengthening Forensic Science in the United States written by National Research Council and published by National Academies Press. This book was released on 2009-07-29 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scores of talented and dedicated people serve the forensic science community, performing vitally important work. However, they are often constrained by lack of adequate resources, sound policies, and national support. It is clear that change and advancements, both systematic and scientific, are needed in a number of forensic science disciplines to ensure the reliability of work, establish enforceable standards, and promote best practices with consistent application. Strengthening Forensic Science in the United States: A Path Forward provides a detailed plan for addressing these needs and suggests the creation of a new government entity, the National Institute of Forensic Science, to establish and enforce standards within the forensic science community. The benefits of improving and regulating the forensic science disciplines are clear: assisting law enforcement officials, enhancing homeland security, and reducing the risk of wrongful conviction and exoneration. Strengthening Forensic Science in the United States gives a full account of what is needed to advance the forensic science disciplines, including upgrading of systems and organizational structures, better training, widespread adoption of uniform and enforceable best practices, and mandatory certification and accreditation programs. While this book provides an essential call-to-action for congress and policy makers, it also serves as a vital tool for law enforcement agencies, criminal prosecutors and attorneys, and forensic science educators.

Returning Individual Research Results to Participants

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Publisher : National Academies Press
ISBN 13 : 0309475201
Total Pages : 399 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Returning Individual Research Results to Participants by : National Academies of Sciences, Engineering, and Medicine

Download or read book Returning Individual Research Results to Participants written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-08-23 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: When is it appropriate to return individual research results to participants? The immense interest in this question has been fostered by the growing movement toward greater transparency and participant engagement in the research enterprise. Yet, the risks of returning individual research resultsâ€"such as results with unknown validityâ€"and the associated burdens on the research enterprise are competing considerations. Returning Individual Research Results to Participants reviews the current evidence on the benefits, harms, and costs of returning individual research results, while also considering the ethical, social, operational, and regulatory aspects of the practice. This report includes 12 recommendations directed to various stakeholdersâ€"investigators, sponsors, research institutions, institutional review boards (IRBs), regulators, and participantsâ€"and are designed to help (1) support decision making regarding the return of results on a study-by-study basis, (2) promote high-quality individual research results, (3) foster participant understanding of individual research results, and (4) revise and harmonize current regulations.

Conflict of Interest in Medical Research, Education, and Practice

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Author :
Publisher : National Academies Press
ISBN 13 : 0309145449
Total Pages : 436 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Conflict of Interest in Medical Research, Education, and Practice by : Institute of Medicine

Download or read book Conflict of Interest in Medical Research, Education, and Practice written by Institute of Medicine and published by National Academies Press. This book was released on 2009-09-16 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collaborations of physicians and researchers with industry can provide valuable benefits to society, particularly in the translation of basic scientific discoveries to new therapies and products. Recent reports and news stories have, however, documented disturbing examples of relationships and practices that put at risk the integrity of medical research, the objectivity of professional education, the quality of patient care, the soundness of clinical practice guidelines, and the public's trust in medicine. Conflict of Interest in Medical Research, Education, and Practice provides a comprehensive look at conflict of interest in medicine. It offers principles to inform the design of policies to identify, limit, and manage conflicts of interest without damaging constructive collaboration with industry. It calls for both short-term actions and long-term commitments by institutions and individuals, including leaders of academic medical centers, professional societies, patient advocacy groups, government agencies, and drug, device, and pharmaceutical companies. Failure of the medical community to take convincing action on conflicts of interest invites additional legislative or regulatory measures that may be overly broad or unduly burdensome. Conflict of Interest in Medical Research, Education, and Practice makes several recommendations for strengthening conflict of interest policies and curbing relationships that create risks with little benefit. The book will serve as an invaluable resource for individuals and organizations committed to high ethical standards in all realms of medicine.

The CTSA Program at NIH

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Publisher : National Academies Press
ISBN 13 : 0309284740
Total Pages : 179 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The CTSA Program at NIH by : Institute of Medicine

Download or read book The CTSA Program at NIH written by Institute of Medicine and published by National Academies Press. This book was released on 2013-10-09 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2006 the National Institutes of Health (NIH) established the Clinical and Translational Science Awards (CTSA) Program, recognizing the need for a new impetus to encourage clinical and translational research. At the time it was very difficult to translate basic and clinical research into clinical and community practice; making it difficult for individual patients and communities to receive its benefits. Since its creation the CTSA Program has expanded, with 61 sites spread across the nation's academic health centers and other institutions, hoping to provide catalysts and test beds for policies and practices that can benefit clinical and translation research organizations throughout the country. The NIH contracted with the Institute of Medicine (IOM) in 2012 to conduct a study to assess and provide recommendations on appropriateness of the CTSA Program's mission and strategic goals and whether changes were needed. The study was also address the implementation of the program by the National Center for Advancing Translational Sciences (NCATS) while exploring the CTSA's contributions in the acceleration of the development of new therapeutics. A 13-member committee was established to head this task; the committee had collective expertise in community outreach and engagement, public health and health policy, bioethics, education and training, pharmaceutical research and development, program evaluation, clinical and biomedical research, and child health research. The CTSA Program at NIH: Opportunities for Advancing Clinical and Translational Research is the result of investigations into previous program evaluations and assessments, open-session meetings and conference class, and the review of scientific literature. Overall, the committee believes that the CTSA Program is significant to the advancement of clinical and translational research through its contributions. The Program would benefit from a variety of revisions, however, to make it more efficient and effective.

Fostering Integrity in Research

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Publisher : National Academies Press
ISBN 13 : 0309391253
Total Pages : 327 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Fostering Integrity in Research by : National Academies of Sciences, Engineering, and Medicine

Download or read book Fostering Integrity in Research written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-01-13 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: The integrity of knowledge that emerges from research is based on individual and collective adherence to core values of objectivity, honesty, openness, fairness, accountability, and stewardship. Integrity in science means that the organizations in which research is conducted encourage those involved to exemplify these values in every step of the research process. Understanding the dynamics that support â€" or distort â€" practices that uphold the integrity of research by all participants ensures that the research enterprise advances knowledge. The 1992 report Responsible Science: Ensuring the Integrity of the Research Process evaluated issues related to scientific responsibility and the conduct of research. It provided a valuable service in describing and analyzing a very complicated set of issues, and has served as a crucial basis for thinking about research integrity for more than two decades. However, as experience has accumulated with various forms of research misconduct, detrimental research practices, and other forms of misconduct, as subsequent empirical research has revealed more about the nature of scientific misconduct, and because technological and social changes have altered the environment in which science is conducted, it is clear that the framework established more than two decades ago needs to be updated. Responsible Science served as a valuable benchmark to set the context for this most recent analysis and to help guide the committee's thought process. Fostering Integrity in Research identifies best practices in research and recommends practical options for discouraging and addressing research misconduct and detrimental research practices.

Social Science Research

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Author :
Publisher : CreateSpace
ISBN 13 : 9781475146127
Total Pages : 156 pages
Book Rating : 4.1/5 (461 download)

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Book Synopsis Social Science Research by : Anol Bhattacherjee

Download or read book Social Science Research written by Anol Bhattacherjee and published by CreateSpace. This book was released on 2012-04-01 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to introduce doctoral and graduate students to the process of conducting scientific research in the social sciences, business, education, public health, and related disciplines. It is a one-stop, comprehensive, and compact source for foundational concepts in behavioral research, and can serve as a stand-alone text or as a supplement to research readings in any doctoral seminar or research methods class. This book is currently used as a research text at universities on six continents and will shortly be available in nine different languages.

Population Health Monitoring

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Author :
Publisher : Springer
ISBN 13 : 3319765620
Total Pages : 227 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Population Health Monitoring by : Marieke Verschuuren

Download or read book Population Health Monitoring written by Marieke Verschuuren and published by Springer. This book was released on 2018-12-17 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely volume presents an in-depth tour of population health monitoring—what it is, what it does, and why it has become increasingly important to health information systems across Europe. Introductory chapters ground readers in the structures of health information systems, and the main theoretical and conceptual models of population health monitoring. From there, contributors offer tools and guidelines for optimum monitoring, including best practices for gathering and contextualizing data and for disseminating findings, to benefit the people most affected by the information. And an extended example follows the step-by-step processes of population health monitoring through a study of health inequalities, from data collection to policy recommendations. Included in the coverage: · Structuring health information: frameworks, models, and indicators · Analysis: contextualization of process and content · Knowledge translation: key concepts, terms, and activities · Health inequality monitoring: a practical application of population health monitoring · Relating population health monitoring to other types of health assessments · Population health monitoring: strengths, weaknesses, opportunities, and threats A robust guide with international implications for an emerging field, Population Health Monitoring is a salient reference for public health experts working in the field of health information as well as post-graduate public health students and public health policymakers. "In this comprehensive and easy to read volume, Verschuuren and van Oers, accompanied by other specialists in the field, present a fresh and thoroughly researched contribution on the discipline of population health monitoring. They critically analyse and describe the phases, functions and approaches to population health monitoring but far more importantly, the discipline is positioned within the wider domains of public health, health policy and health systems. The book is definitely highly recommended reading for students of public health and health services management but is also a useful refresher course for public health practitioners." Natasha Azzopardi Muscat, President, European Public Health Association Chapter 7 of this book is available open access under a CC BY 3.0 IGO license at link.springer.com Chapter 8 of this book is available open access under a CC BY 3.0 IGO license at link.springer.com