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Localized Surface Plasmon Resonance Spectroscopy For Fundamental Studies Of Nanoparticle Optics And Applications To Biosensors
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Book Synopsis Localized Surface Plasmon Resonance Spectroscopy for Fundamental Studies of Nanoparticle Optics and Applications to Biosensors by : Amanda Jo Haes
Download or read book Localized Surface Plasmon Resonance Spectroscopy for Fundamental Studies of Nanoparticle Optics and Applications to Biosensors written by Amanda Jo Haes and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This work reveals that triangular silver nanoparticles have remarkable optical properties and that the enhanced sensitivity of their nanoenvironment can be used as a new class of optical sensors using localized surface plasmon resonance (LSPR) spectroscopy. The contents of thesis can be divided into two main subject areas: (1) the characterization and optimization of nanoparticles for the basic understanding of their optical properties and (2) the development, testing, and theoretical understanding of model biological assays and nonmodel assays for disease diagnosis. In the first half of this work, an improved understanding of the physical characteristics of noble metal nanoparticles is explored. Specifically, the realization that the sensitivity of these nanoparticles can be optimized for a given adsorbate is revealed. First, it is demonstrated that the short range (viz., 0--3 nm) distance dependence of the electromagnetic fields that surround these nanoparticles can be systematically tuned by changing their composition, size, and structure. Second, multilayer shells are assembled onto surface-confined noble metal nanoparticles to study the long range distance dependence. It is shown that this dependence (viz., 3--35 nm) is non-linear and has a tunable sensing range. Finally, methods to enhance the nanosensor's response based on interactions between the nanoparticle's plasmon resonance and the adsorbate's molecular resonance is revealed. In the remainder sections, we explore the use of these nanoparticles as biological sensors. First, the model system of biotin/streptavidin is confirmed to be highly specific with low nonspecific influences. Next, the demonstration of an immunoassay (biotin/anti-biotin) is performed. Finally, the LSPR nanosensor is shown to be a promising platform for the possible mechanistic understanding of Alzheimer's disease.
Book Synopsis Localized Surface Plasmon Resonance Based Nanobiosensors by : Yi-Tao Long
Download or read book Localized Surface Plasmon Resonance Based Nanobiosensors written by Yi-Tao Long and published by Springer Science & Business Media. This book was released on 2014-04-10 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the fundamentals and applications of the localized surface plasmon resonance (LSPR) property of noble metallic nanoparticles, with an emphasis on the biosensing applications of plasmonic nanoparticles, especially in living cell imaging and photothermal therapy. It provides an overview of the different operating principles of plasmonic sensors, particularly the single-nanoparticle-based detections, and a series of creative biosensors based on the modulation of different parameters of nanoparticles (particle size, shape, composition and surrounding medium) for label-free detection. The interparticle coupling effect, plasmon resonance energy transfer, electron transfer on plasmonics surface are also covered in this book. This book is intended for graduate students and researchers working in the interdisciplinary field combining chemistry, biology, material science and nanophotonics. Yi-Tao Long is a Professor at the School of Chemistry and Molecular Engineering, East China University of Science and Technology, China.
Book Synopsis Nanoplasmonic Sensors by : Alexandre Dmitriev
Download or read book Nanoplasmonic Sensors written by Alexandre Dmitriev and published by Springer Science & Business Media. This book was released on 2012-07-31 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compendium of the finest research in nanoplasmonic sensing done around the world in the last decade. It describes basic theoretical considerations of nanoplasmons in the dielectric environment, gives examples of the multitude of applications of nanoplasmonics in biomedical and chemical sensing, and provides an overview of future trends in optical and non-optical nanoplasmonic sensing. Specifically, readers are guided through both the fundamentals and the latest research in the two major fields nanoplasmonic sensing is applied to – bio- and chemo-sensing – then given the state-of-the-art recipes used in nanoplasmonic sensing research.
Book Synopsis Nanoplasmonics by : Grégory Barbillon
Download or read book Nanoplasmonics written by Grégory Barbillon and published by BoD – Books on Demand. This book was released on 2017-06-21 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoplasmonics is a young topic of research, which is part of nanophotonics and nano-optics. Nanoplasmonics concerns to the investigation of electron oscillations in metallic nanostructures and nanoparticles. Surface plasmons have optical properties, which are very interesting. For instance, surface plasmons have the unique capacity to confine light at the nanoscale. Moreover, surface plasmons are very sensitive to the surrounding medium and the properties of the materials on which they propagate. In addition to the above, the surface plasmon resonances can be controlled by adjusting the size, shape, periodicity, and materials' nature. All these optical properties can enable a great number of applications, such as biosensors, optical modulators, photodetectors, and photovoltaic devices. This book is intended for a broad audience and provides an overview of some of the fundamental knowledges and applications of nanoplasmonics.
Book Synopsis Nanomaterials for Biosensors by : Bansi D. Malhotra
Download or read book Nanomaterials for Biosensors written by Bansi D. Malhotra and published by William Andrew. This book was released on 2017-10-26 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials for Biosensors: Fundamentals and Applications provides a detailed summary of the main nanomaterials used in biosensing and their application. It covers recent developments in nanomaterials for the fabrication of biosensor devices for healthcare diagnostics, food freshness and bioprocessing. The various processes used for synthesis and characterization of nanostructured materials are examined, along with the design and fabrication of bioelectronic devices using nanostructured materials as building blocks. Users will find the fundamentals of the main nanomaterials used in biosensing, helping them visualize a systematic and coherent picture of how nanomaterials are used in biosensors. The book also addresses the role of bio-conjugation of nanomaterials in the construction of nano-biointerfaces for application in biosensors. Such applications, including metal nanoparticles, metal oxide nanoparticles, nanocomposites, carbon nanotubes, conducting polymers and plasmonic nanostructures in biosensing are discussed relative to each nanomaterial concerned. Finally, recent advancements in protein functionalized nanomaterials for cancer diagnostics and bio-imaging are also included. Provides a detailed study on how nanomaterials are used to enhance sensing capabilities in biosensors Explains the properties, characterization methods and preparation techniques of the nanomaterials used in biosensing Arranged in a material-by-material way, making it clear how each nanomaterial should be used
Book Synopsis Engineering the Surface Chemistries of Plasmonic Nanoparticles for Biosensing Applications by : Matthew Nathaniel Creyer
Download or read book Engineering the Surface Chemistries of Plasmonic Nanoparticles for Biosensing Applications written by Matthew Nathaniel Creyer and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasmonic nanoparticles (PNs) have unique optical properties that make them particularly attractive for biosensing applications. These properties arise due the localized surface plasmon resonance (LSPR) on their surface which occurs upon light excitation that is typically in the visible region of the electromagnetic spectrum. The absorbing and scattering properties of PNs are derived from the LSPR and are tunable based on the nanoparticle shape, size, and local dielectric environment. Furthermore, the LSPR on PNs enables fluorophores in close proximity (
Book Synopsis Nanoantenna by : Marc Lamy de la Chapelle
Download or read book Nanoantenna written by Marc Lamy de la Chapelle and published by CRC Press. This book was released on 2013-01-24 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book concentrates on the various fields related to the development of a nanobiosensor and presents the latest information from renowned experts. It focuses on the enhanced spectroscopy, including SERS, SEIRA/SEIRS, and near-field optics, and the related physical processes (optical properties of metallic nanoparticles, plasmon resonance, field
Book Synopsis Plasmonics-Based Optical Sensors and Detectors by : Banshi D. Gupta
Download or read book Plasmonics-Based Optical Sensors and Detectors written by Banshi D. Gupta and published by CRC Press. This book was released on 2023-08-24 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasmonics stems from the surface charge density oscillations at metal–dielectric interface, leading to extremely strong light–matter interactions. In the past few decades, plasmonics has become one of the most favorite fields/techniques in realizing high-performance photonic devices. For this purpose, different new concepts, such as exploration of different radiation frequency regions, two-dimensional materials/heterostructures, and different types of substrates for the excitation of plasmons have been investigated for plasmonics-based sensors and detectors. This book focuses on the recent and advanced works on optical sensors and detectors utilizing plasmonic techniques for opto-electronic applications. The book is unique as it describes both sensors and detectors based on plasmonics and their practical applications in a single book, a feature not found in any book so far.
Book Synopsis Localized Surface Plasmon Resonance for Optical Fiber-Sensing Applications by : Pedro J. Rivero
Download or read book Localized Surface Plasmon Resonance for Optical Fiber-Sensing Applications written by Pedro J. Rivero and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: It is well known that optical fiber sensors have attracted the attention of scientific community due to its intrinsic advantages, such as lightweight, small size, portability, remote sensing, immunity to electromagnetic interferences and the possibility of multiplexing several signals. This field has shown a dramatic growth thanks to the creation of sensitive thin films onto diverse optical fiber configurations. In this sense, a wide range of optical fiber devices have been successfully fabricated for monitoring biological, chemical, medical or physical parameters. In addition, the use of nanoparticles into the sensitive thin films has resulted in an enhancement in the response time, robustness or sensitivity in the optical devices, which is associated to the inherent properties of nanoparticles (high surface area ratio or porosity). Among all of them, the metallic nanoparticles are of great interest for sensing applications due to the presence of strong absorption bands in the visible and near-infrared regions, due to their localized surface plasmon resonances (LSPR). These optical resonances are due to the coupling of certain modes of the incident light to the collective oscillation of the conduction electrons of the metallic nanoparticles. The LSPR extinction bands are very useful for sensing applications as far as they can be affected by refractive index variations of the surrounding medium of the nanoparticles, and therefore, it is possible to create optical sensors with outstanding properties such as high sensitivity and optical self-reference. In this chapter, the attractive optical properties of metal nanostructures and their implementation into different optical fiber configuration for sensing or biosensing applications will be studied.
Book Synopsis Recent Advances in Plasmonic Probes by : Rajib Biswas
Download or read book Recent Advances in Plasmonic Probes written by Rajib Biswas and published by Springer Nature. This book was released on 2022-06-21 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a comprehensive overview of recent advancements in both theory and practical implementation of plasmonic probes. Encompassing multiple disciplines, the field of plasmonics provides a versatile and flexible platform for nanoscale sensing and imaging. Despite being a relatively young field, plasmonic probes have come a long way, with applications in chemical, biological, civil, and architectural fields as well as enabling many analytical schemes such as immunoassay, biomarkers, environmental indexing, and water quality sensing, to name but a few. The objective of the book is to present in-depth analysis of the theory and applications of novel probes based on plasmonics, with a broad selection of specially-invited chapters on the development, fabrication, functionalization, and implementation of plasmonic probes as well as their integration with current technologies and future outlook. This book is designed to cater to the needs of novice, seasoned researchers and practitioners in academia and industry, as well as medical and environmental fields.
Book Synopsis Optical Guided-wave Chemical and Biosensors I by : Mohammed Zourob
Download or read book Optical Guided-wave Chemical and Biosensors I written by Mohammed Zourob and published by Springer Science & Business Media. This book was released on 2010-03-18 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the first time, distinguished scientists from key institutions worldwide provide a comprehensive approach to optical sensing techniques employing the phenomenon of guided wave propagation for chemical and biosensors. This includes both state-of the-art fundamentals and innovative applications of these techniques. The authors present a deep analysis of their particular subjects in a way to address the needs of novice researchers such as graduate students and post-doctoral scholars as well as of established researchers seeking new avenues. Researchers and practitioners who need a solid foundation or reference will find this work invaluable. This first of two volumes contains eight chapters covering planar waveguides for sensing, as well as sensing techniques based on plasmonic waveguides.
Book Synopsis Localized Surface Plasmon Resonance Spectroscopy of Silver Nanoparticles and Raman Spectroscopy Using Liquid-core Optical Fibers by : Michelle Duval Malinsky
Download or read book Localized Surface Plasmon Resonance Spectroscopy of Silver Nanoparticles and Raman Spectroscopy Using Liquid-core Optical Fibers written by Michelle Duval Malinsky and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Complex Magnetic Nanostructures by : Surender Kumar Sharma
Download or read book Complex Magnetic Nanostructures written by Surender Kumar Sharma and published by Springer. This book was released on 2017-04-04 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a detailed discussion of the complex magnetic behavior of magnetic nanosystems, with its myriad of geometries (e.g. core-shell, heterodimer and dumbbell) and its different applications. It provides a broad overview of the numerous current studies concerned with magnetic nanoparticles, presenting key examples and an in-depth examination of the cutting-edge developments in this field. This contributed volume shares the latest developments in nanomagnetism with a wide audience: from upper undergraduate and graduate students to advanced specialists in both academia and industry. The first three chapters serve as a primer to the more advanced content found later in the book, making it an ideal introductory text for researchers starting in this field. It provides a forum for the critical evaluation of many aspects of complex nanomagnetism that are at the forefront of nanoscience today. It also presents highlights from the extensive literature on the topic, including the latest research in this field.
Book Synopsis Handbook of Surface Plasmon Resonance by : Richard B. M. Schasfoort
Download or read book Handbook of Surface Plasmon Resonance written by Richard B. M. Schasfoort and published by Royal Society of Chemistry. This book was released on 2017-05-30 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events, this book provides a total system description including optics, fluidics and sensor surfaces for a wide researcher audience.
Book Synopsis Nanoscience And Technology: A Collection Of Reviews From Nature Journals by : Peter Rodgers
Download or read book Nanoscience And Technology: A Collection Of Reviews From Nature Journals written by Peter Rodgers and published by World Scientific. This book was released on 2009-08-21 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains 35 review articles on nanoscience and nanotechnology that were first published in Nature Nanotechnology, Nature Materials and a number of other Nature journals. The articles are all written by leading authorities in their field and cover a wide range of areas in nanoscience and technology, from basic research (such as single-molecule devices and new materials) through to applications (in, for example, nanomedicine and data storage).
Book Synopsis Optical Whispering Gallery Modes for Biosensing by : Frank Vollmer
Download or read book Optical Whispering Gallery Modes for Biosensing written by Frank Vollmer and published by Springer Nature. This book was released on 2020-10-16 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This interdisciplinary book covers the fundamentals of optical whispering gallery mode (WGM) microcavities, light–matter interaction, and biomolecular structure with a focus on applications in biosensing. Novel biosensors based on the hybridization of WGM microcavities and localized surface plasmon resonances (LSPRs) in metal nanoparticles have emerged as the most sensitive microsystem biodetection technology that boasts single molecule detection capability without the need for amplification and labeling of the analyte. The book provides an ample survey of the physical mechanisms of WGMs and LSPRs for detecting affinity, concentration, size, shape and orientation of biomarkers, while informing the reader about different classes of biomolecules, their optical properties and their importance in label-free clinical diagnostics. For the more advanced reader, advanced applications of WGMs and LSPRs in exploring the fundamental nature of quantum physics are discussed.
Book Synopsis Localized Surface Plasmon Resonance for Biosensing Lab-on-a-chip Applications by : Srdjan S. Acomovic
Download or read book Localized Surface Plasmon Resonance for Biosensing Lab-on-a-chip Applications written by Srdjan S. Acomovic and published by . This book was released on 2013 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent times, metallic nanoparticle plasmonics coupled with applications towards biosensing has gathered momentum to the point where commercial R&D are investing large resources in developing the so-called localized surface plasmon resonance (LSPR) biosensors. Conceptually, the main motivation for the research presented within this thesis is achievement of fully-operational LSPR biosensor interfaced with the state-of-the-art microfluidics, allowing for very precise control of sample manipulation and stable read-out. LSPR sensors are specifficaly engineered by electron beam lithography nanofabrication technique, where nanoparticle interactions are optimized to exhibit increased sensitivity and higher signal-to-noise ratio. However, the overall performance of LSPR lab-on-a-chip device depends critically on the biorecognition layer preparation in combination with surface passivation. As an introduction, the principles of plasmonic biosensing are identified encompassing both Surface Plasmon Resonance (SPR) and Localized SPR. Being successfully implemented into commercial product, the governing physics of SPR is compared to LSPR in chapter 1, together with advantages and disadvantages of both. Chapter 2 describes methods necessary for LSPR biosensor development, beginning with nano-fabrication methods, the modelling tool (COMSOL Multiphisics), while the basics of micro-fabrication in microfluidics conclude this chapter, where passive and active microfluidics networks are discerned. Particularly attractive optical properties are exhibited by closely-coupled nanoparticles (dimers), with the dielectric gap of below tens of nm, which were theoretically predicted to be very suitable as LSPR biosensing substrates. Chapter 3 is subjected to optical characterization (dependence on the size of the dielectric gap) of nanofabricated dimer arrays. The acquired data demonstrate the advantages of the nanofabrication methods presented in chapter 2 and the technique for fast and reliable determination of nanoparticle characteristic parameters. The initial biosensing-like experiments presented in chapter 4 (no integration with microfluidics) proved for the first time, the theoretical predictions of higher sensitivity, yielding additionally the specific response as function of analyte size and dielectric gap between nanoparticles. The overall response of different dimer arrays (various gaps) provides information about adopted conformation of analyte protein once immobilized. Broad resonances of dimers feature higher noise when employing them for the real-time LSPR biosensing. As a way to circumvent such problem, the feasibility of employing far-field interaction within the nanoparticle array to spectrally narrow resonance is investigated in chapter 5 by optimizing the array periodicity and introducing thin waveguiding layers. Finally, the concluding chapter 6 is dedicated to a full assembly of a Lab-on-a-chip (LOC) LSPR biosensor, starting with interfacing plasmonic substrates with compatible active microfluidic networks, allowing the precise sample delivery and multiplexing. The prototype device consisting of 8 individual sensors is presented with typical modes of operation. The bulk refractive index determination of various samples demonstrates the working principle of such device. Finally, various strategies of biorecognition layer formation are discussed within the on-going research.
