Liver Pathology and Alcohol

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461204216
Total Pages : 622 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Liver Pathology and Alcohol by : Roland R. Watson

Download or read book Liver Pathology and Alcohol written by Roland R. Watson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol and other drugs of abuse are major contributing factors to liver disease and its pathology. Alcoholic cirrhosis causes thousands of deaths each year in the United States, and encourages liver replacement. A better understanding of the mechanisms of liver pathology will significantly aid basic researchers and physicians in treating and preventing liver damage. This book is designed especially for those researchers wishing to understand alcoholic liver disease. Therefore the role of alcohol in changing nutrition and its nutritional effects on liver disease are reviewed. The generation of free radicals during alcohol use has been found to be an important cause of membrane changes, of cancer development, and of lipid alterations-and thus of liver pathology. In addition to alcohol, other drugs of abuse, including morphine, cocaine, marijuana, and caffeine have also been shown to be significant contributors to liver pathology. The prevalence of drug and alcohol use and abuse today means that liver disease will continue as a major social and medical problem. The explanation of its biological origins cannot fail to help us better understand and treat the disease in the years to come.

Alcoholic and Non-Alcoholic Fatty Liver Disease

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Author :
Publisher : Springer
ISBN 13 : 3319205382
Total Pages : 372 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Alcoholic and Non-Alcoholic Fatty Liver Disease by : Naga Chalasani

Download or read book Alcoholic and Non-Alcoholic Fatty Liver Disease written by Naga Chalasani and published by Springer. This book was released on 2015-12-10 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the first text to concisely yet comprehensively cover developments for both alcoholic and nonalcoholic fatty liver disease in an organized fashion. Aspects of these two diseases covered in the book include global epidemiology and risk factors, pathogenesis, animal models, hepatic and extra-hepatic malignancies, treatment models, and current and emerging therapies. Written by experts in the field, Alcoholic and Non-Alcoholic Fatty Liver Disease: Bench to Bedside is a valuable resource for gastroenterologists, pathologists, and hepatologists who treat patients with alcoholic and nonalcoholic fatty liver disease.

Variceal Hemorrhage

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Publisher : Springer Science & Business Media
ISBN 13 : 1493900021
Total Pages : 266 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Variceal Hemorrhage by : Roberto de Franchis

Download or read book Variceal Hemorrhage written by Roberto de Franchis and published by Springer Science & Business Media. This book was released on 2014-01-25 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Variceal Hemorrhage provides an update of the evidence concerning several aspects of variceal hemorrhage. The book features new information on natural history, diagnosis of esophageal varices, assessment of the risk of bleeding and identification of high risk groups and patients who may benefit or be harmed from different treatments. The volume also presents a critical analysis of the different steps in the management of acute variceal bleeding. Authored by the most prominent world experts in their areas of expertise, Variceal Hemorrhage serves as a very useful reference for gastroenterologists, GI surgeons, residents in internal medicine and physicians dealing with and interested in the different aspects of this severe medical emergency.

Alcoholic Liver Disease, An Issue of Clinics in Liver Disease, E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323459749
Total Pages : 209 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Alcoholic Liver Disease, An Issue of Clinics in Liver Disease, E-Book by : Stanley Cohen

Download or read book Alcoholic Liver Disease, An Issue of Clinics in Liver Disease, E-Book written by Stanley Cohen and published by Elsevier Health Sciences. This book was released on 2016-07-15 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol abuse remains a significant problem world-wide. The most commonly affected organ remains the liver with a risk of alcoholic liver disease (ALD) which can range from asymptomatic to alcoholic hepatitis to alcoholic cirrhosis. In 2010, alcohol-attributable cirrhosis was responsible for 0.9% of all global deaths. Given the sheer magnitude of alcohol abuse and alcoholic liver disease, an update on this topic is pertinent and relevant. This issue will focus on a variety of topics including alcoholism, the pathogenesis of ALD, the spectrum of ALD, the pathology of ALD, and the long-term management of patients with ALD. Alcoholic hepatitis is a particular type of ALD with a high mortality. This issue will explore the syndrome of alcoholic hepatitis, its prognostic markers, and the available therapies. Because alcohol intake can influence so many other conditions of the liver (especially hepatitis C), articles in this issue will also explore the impact of alcohol abuse on other liver conditions. In addition, several other topics such as nutritional therapy for ALD, ALD and liver cancer, and ALD and infection risk will be explored. Also, even though it is quite controversial, we will also explore liver transplant as a therapy for alcoholic liver disease including alcoholic hepatitis.

Alcohol and the Liver

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Author :
Publisher : Nova Science Publishers
ISBN 13 : 9781634844000
Total Pages : 0 pages
Book Rating : 4.8/5 (44 download)

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Book Synopsis Alcohol and the Liver by : Gerond V. Lake-Bakaar

Download or read book Alcohol and the Liver written by Gerond V. Lake-Bakaar and published by Nova Science Publishers. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The topic of alcohol and the liver is long overdue for re-evaluation. The authors of this book have clearly taken up this challenge. Human interest in alcohol dates back to the Neolithic period (circa 10,000 BC). Only a small amount of alcohol is found naturally in food. Therefore, humans have yet to adapt to the high quantities of alcohol consumed daily by alcohol abusers. Alcohol is a simple carbohydrate and is metabolised as a fuel. However, unlike more naturally occurring carbohydrates such as glucose, the pathways for its metabolism are not subject to the same checks and balances. Ethanol oxidation reduces NAD+, which starves reactions that depend on this substrate. This accounts for the accumulation of fat in alcoholic steatosis. Alcohol metabolism generates significant amounts of reactive oxygen species (ROS), which damages mtDNA and subsequently mitochondrial integrity. The authors provide several lines of evidence that link the clinical picture of alcoholic liver disease with mitochondrial damage. Other important topics highlighted in this book include histo-pathological aspects of the disease. Clinical assessment of nutrition and vitamin supplementation is addressed as well. The book concludes with the highly topical and controversial aspect of liver transplantation in patients with alcoholic liver disease.

Alcoholic Liver Disease

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Author :
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Alcoholic Liver Disease by : Pauline Hall (MB, BS, FRCPA.)

Download or read book Alcoholic Liver Disease written by Pauline Hall (MB, BS, FRCPA.) and published by John Wiley & Sons. This book was released on 1985 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Alcoholic Liver Disease, An Issue of Clinics in Liver Disease

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323654525
Total Pages : pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Alcoholic Liver Disease, An Issue of Clinics in Liver Disease by : Norman L. Sussman

Download or read book Alcoholic Liver Disease, An Issue of Clinics in Liver Disease written by Norman L. Sussman and published by Elsevier Health Sciences. This book was released on 2018-11-21 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcoholic liver disease has once again entered our collective conscience. A paper in 2012 showed the utility of orthotopic liver transplantation (OLT) in acute alcoholic hepatitis. As expected, this opened the floodgates. Every liver transplant program in the USA is now under pressure to list and transplant patients with alcoholic liver disease (ALD), resulting n a shift in the type of patients to admit and list for OLT. In consultation with Dr. Norman Gitlin, Dr. Norman Sussman and Dr. Michael Lucey have put together a collection of articles on current practices and future trends in the management of alcohol-related diseases. Expert authors from top institutions have contributed articles on the following topcs: Histopathology; Alcohol and the Law; Alcoholic Liver Disease in Children; Alcohol Use Disorder; Pathogenesis of ALD; Acute Alcoholic Hepatitis; Nutrition and Malnutrition in ALD; Alcoholic Cirrhosis; Liver Transplantation for Alcoholic Liver Disease; CNS effects of Alcohol; and Will Studies in NASH Help to Manage AS. Readers will come away with current clinical information to help them to make clinical decisions that will improve patient outcomes.

A Practical Approach to the Spectrum of Alcoholic Liver Disease, An Issue of Clinics in Liver Disease - E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1455747378
Total Pages : 240 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis A Practical Approach to the Spectrum of Alcoholic Liver Disease, An Issue of Clinics in Liver Disease - E-Book by : David Bernstein

Download or read book A Practical Approach to the Spectrum of Alcoholic Liver Disease, An Issue of Clinics in Liver Disease - E-Book written by David Bernstein and published by Elsevier Health Sciences. This book was released on 2012-11-14 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Guest Editor has organized this issue to focus on the clinical management of alcoholic liver disease. Authors have written state-of-the-art reviews on the following topics: Prevalence and Natural History of ALD; Alcohol Metabolism; Immunology in ALD; Histological Findings in ALD; Diagnosis and Management of Alcoholic Hepatitis; Management of Alcohol Abuse; Long Term Management of Alcoholic Liver Disease; Infections in ALD; Nutrition in ALD; Alcohol’s Effect on Other Chronic Liver Diseases; Liver Cancer and Alcohol; Evaluation and Selection of Candidates for Liver Transplantation; and ALD and Specific Transplant-Related Issues.

Alcohol and the Liver

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461341841
Total Pages : 399 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Alcohol and the Liver by : M. Fisher

Download or read book Alcohol and the Liver written by M. Fisher and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol abuse is this culture's most important drug problem. Statistics indicate that it is exacting a great and relentlessly increasing toll of human suffering. It is clear that the problem is not being dealt with in any effective manner. At the invitation of the. Canadian Hepatic Foundation, many of the world's experts gathered in Toronto, May 14-15 1976, to focus attention on one of the most important aspects of the alcohol problem -alcohol induced liver damage. The epidemiology of alcohol induced liver disease was discussed and current views on the pathogenesis of the problem were reviewed. New insight into the pathological alterations of the liver was presented and some of our current therapeutic capabilities were discussed. Dr. Hans Popper summarized the Symposium and presented some of his views on those aspects of the problem which will require early attention by the research community. The Symposium achieved its immediate objective -that of bringing together the committed experts of various disciplines for an updating of our understanding of alcohol and the liver and for a discussion of new approaches to the problem. As a backdrop to the Symposium, however, was large writing on the wall to the effect that we are expending our research talents and efforts on a totally unnecessary problem. Right now we probably know enough and have sufficient resources at our disposal to solve the problem.

Alcoholic Liver Pathology

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Publisher :
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Alcoholic Liver Pathology by : Addiction Research Foundation of Ontario

Download or read book Alcoholic Liver Pathology written by Addiction Research Foundation of Ontario and published by . This book was released on 1975 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Alcohol Abuse and Liver Disease

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118887298
Total Pages : 264 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Alcohol Abuse and Liver Disease by : Andrea DiMartini

Download or read book Alcohol Abuse and Liver Disease written by Andrea DiMartini and published by John Wiley & Sons. This book was released on 2016-03-21 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: For people with alcohol excess and liver disease, successful management must be two-fold with management of both their psychological/physical addiction to alcohol and their liver disease. Alcohol Abuse and liver disease, with its joint focus on hepatology and psychiatry, provides both hepatologists and psychiatrists of all levels with a practical, concise and didactic guide to the investigation and clinical management of those with alcohol-related problems. Edited by a practicing hepatologist in the UK and a practising specialist in psychiatry/substance abuse in the US, it covers areas such as: • Risk factors for alcoholic liver disease • Interaction of alcohol with other co-morbidities • Clinical assessment of alcohol intake • Detoxification and management of withdrawal • Psychotherapeutic and pharmaceutical interventions • Treatment of liver disease Key points, management diagrams and high-quality images are all be supported by the very latest in clinical guidelines from the major hepatology and psychiatry societies such as the APA, EPA, AASLD and EASL. With increasing emphasis on multi-disciplinary speciality care in this area, this is the ideal tool to consult in order to provide the best care possible care for what are very challenging patients to manage.

The Liver

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Publisher : John Wiley & Sons
ISBN 13 : 1119436826
Total Pages : 1156 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis The Liver by : Irwin M. Arias

Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Global Status Report on Alcohol and Health 2018

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Publisher : World Health Organization
ISBN 13 : 9241565632
Total Pages : 472 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Global Status Report on Alcohol and Health 2018 by : World Health Organization

Download or read book Global Status Report on Alcohol and Health 2018 written by World Health Organization and published by World Health Organization. This book was released on 2019-02-14 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The report provides an overview of alcohol consumption and harms in relation to the UN Sustainable Development Goals (Chapter 1) presents global strategies action plans and monitoring frameworks (Chapter 2) gives detailed information on: the consumption of alcohol in populations (Chapter 3); the health consequences of alcohol consumption (Chapter 4); and policy responses at national level (Chapter 5). In its final chapter 6 the imperative for reducing harmful use of alcohol in a public health perspective is presented. In addition the report contains country profiles for WHO Member States and appendices with statistical annexes a description of the data sources and methods used to produce the estimates and references.

Liver Transplantation

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Publisher : John Wiley & Sons
ISBN 13 : 1119633990
Total Pages : 592 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Liver Transplantation by : James Neuberger

Download or read book Liver Transplantation written by James Neuberger and published by John Wiley & Sons. This book was released on 2021-02-25 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore this practical and step-by-step guide to managing liver transplant patients from leading international clinicians in Hepatology The newly revised Second Edition of Liver Transplantation: Clinical Assessment and Management delivers expert clinical guidance on best practices in managing the care of liver transplant patients. Authors are all experts in their field and cover a world-wide perspective. Organized in an accessible, stepwise fashion and packed with text features such as key points, the book covers all critical areas of each stage of the liver transplant journey, from assessment, to management on the list, to long term care. Readers will learn when to refer a patient for liver transplantation, how to assess a potential liver transplant recipient, learn the principles of the procedure and the long term management of the transplant recipient. Liver Transplantation provides the entire hepatology and surgical team the information required for a sound understanding of the entire procedure, from pre- to post-operative care and management. Clinically oriented and management-focused, the book is far more accessible than the liver transplant sections in traditional hepatology textbooks. Readers will also enjoy: A thorough discussion of when to refer a patient for liver transplantation, including general considerations and the use and abuse of prognostic models An exploration of the selection, assessment, and management of patients on the transplant list, including how to manage a patient with chronic liver disease while on the waiting list A treatment of liver transplantation for acute liver failure (ALF), including assessment and management of ALF patients on the transplant waiting list A discussion of care of the liver transplant recipient after the procedure in the short and long term Perfect for gastroenterologists, hepatologists, and surgeons and other health care professionals managing patients with liver disease who are awaiting, undergoing and following liver transplantation, Liver Transplantation: Clinical Assessment and Management will also earn a place in the libraries of medical students, residents, internal medicine physicians, and GI/Hepatology trainees and all health care professionals providing clinical care to people with liver disease, before, during and after transplantation.

Drug-Induced Liver Injury

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Author :
Publisher : Academic Press
ISBN 13 : 0128173173
Total Pages : 288 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Drug-Induced Liver Injury by :

Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Alcohol Related Diseases in Gastroenterology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642700489
Total Pages : 690 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Alcohol Related Diseases in Gastroenterology by : Helmut K. Seitz

Download or read book Alcohol Related Diseases in Gastroenterology written by Helmut K. Seitz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol abuse ranks among the most common and also the most severe environmental hazards to human health. Its significance is heightened by the possibility of prevention by elimination of the habit, however, rarely exerted. The incidence of deleterious effects on human health has relentlessly risen in the past years for a variety of factors. They include migration of populations and, particularly, increased urbanization. Thus, in some parts of the world, population groups previously spared have become involved, which is also re flected in the increasing number of breweries and distilleries in the developing countries. Social, religious, and gender-related barriers to alcohol consumption are loosening, and the financial improvement of some segments of populations now enable them to buy alcoholic beverages. Thus the greatest percentage rise in the United States has recently been in black women. Adolescents and young people drink more alcoholic beverages than ever, and growing alcohol abuse by pregnant women has let to an increase of the incidence of the fetal alcohol syndrome. While the social and behavioral, including psychiatric, consequences of alcoholism are staggering, the gastrointestinal and, particularly, hepatic manifestations are the most widespread somatic effects, and chronic hepatic disease in alcoholics appears to cause the greatest cost to society. Indeed, mortality from liver cirrhosis is considered a reliable index of alcohol consumption in a country.

Trends in Alcoholic Liver Disease Research

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9533079851
Total Pages : 236 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Trends in Alcoholic Liver Disease Research by : Ichiro Shimizu

Download or read book Trends in Alcoholic Liver Disease Research written by Ichiro Shimizu and published by BoD – Books on Demand. This book was released on 2012-01-11 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcoholic liver disease occurs after prolonged heavy drinking. Not everyone who drinks alcohol in excess develops serious forms of alcoholic liver disease. It is likely that genetic factors determine this individual susceptibility, and a family history of chronic liver disease may indicate a higher risk. Other factors include being overweight and iron overload. This book presents state-of-the-art information summarizing the current understanding of a range of alcoholic liver diseases. It is hoped that the target readers - hepatologists, clinicians, researchers and academicians - will be afforded new ideas and exposed to subjects well beyond their own scientific disciplines. Additionally, students and those who wish to increase their knowledge will find this book a valuable source of information.