Liver Diseases And Hepatic Sinusoidal Cells

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Liver Diseases and Hepatic Sinusoidal Cells

Author : Kyuichi Tanikawa
Publisher : Springer Science & Business Media
ISBN 13 : 4431679359
Total Pages : 547 pages
Book Rating : 4.4/5 (316 download)

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Book Synopsis Liver Diseases and Hepatic Sinusoidal Cells by : Kyuichi Tanikawa

Download or read book Liver Diseases and Hepatic Sinusoidal Cells written by Kyuichi Tanikawa and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatic sinusoidal cells such as sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, and pit cells play an important role in hemodynamic and metabolic function and are involved in various liver diseases. The frequent involvement of sinusoidal cells in pathologic conditions is explained by the diverse actions of those cells, an understanding of which is essential to clinicians. Generously illustrated, this volume presents results of recent studies on hepatic sinusoidal cells in liver diseases, with an introduction to the structure and function of the various types of sinusoidal cells. The in-depth focus of the book is on the role of hepatic sinusoidal cells in relation to liver injury and regeneration, hepatic sinusoidal microcirculation, alcoholic liver diseases, hepatic fibrosis, liver tumor, liver transplantation, cholestasis, and congenital lipidosis, thus providing a valuable reference source for practitioners and researchers.

Sinusoidal Cells in Liver Diseases

Author : Jordi Gracia-Sancho
Publisher : Elsevier
ISBN 13 : 0323952631
Total Pages : 564 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Sinusoidal Cells in Liver Diseases by : Jordi Gracia-Sancho

Download or read book Sinusoidal Cells in Liver Diseases written by Jordi Gracia-Sancho and published by Elsevier. This book was released on 2024-04-09 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sinusoidal Cells in Liver Diseases: Role in their Pathophysiology, Diagnosis, and Treatment provides a state-of-the-art review on recent advances surrounding the role of liver sinusoidal cells (LSECs, HSCs, macrophages, and other non-parenchymal cells) in acute and chronic liver diseases. Coverage emphasizes disease pathophysiology, novel mechanisms, unmet clinical questions, development of biomarkers and treatment opportunities. By focusing on the role of sinusoidal cells in human liver diseases, this reference provides a comprehensive overview of the role of sinusoidal cells in acute and chronic liver diseases, in its pathophysiology and mechanisms, and in the development of novel biomarkers and new therapeutics. Cells of the liver vasculature play an essential role in the pathophysiology of acute and chronic liver diseases and are considered key therapeutic targets to treat most of human hepatopathies. Coverage in this reference includes the phenotypic changes occurring in liver vascular cells and how cells contribute to the development of microcirculatory dysfunction, fibrosis, inflammation, and liver failure. - Provides a comprehensive update on the role of sinusoidal cells in acute and chronic liver diseases - Covers our current understanding of the role of sinusoidal cells as therapeutic targets to improve liver diseases - Presents the latest research in the development of novel biomarkers of liver diseases that derive from sinusoidal cells

Roles of Liver Sinusoidal Endothelial Cells in Liver Homeostasis and Disease

Author : Patricia Lalor
Publisher : Frontiers Media SA
ISBN 13 : 2889747948
Total Pages : 174 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Roles of Liver Sinusoidal Endothelial Cells in Liver Homeostasis and Disease by : Patricia Lalor

Download or read book Roles of Liver Sinusoidal Endothelial Cells in Liver Homeostasis and Disease written by Patricia Lalor and published by Frontiers Media SA. This book was released on 2022-03-30 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Signaling Pathways in Liver Diseases

Author : Jean-Francois Dufour
Publisher : John Wiley & Sons
ISBN 13 : 1118663357
Total Pages : 517 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Signaling Pathways in Liver Diseases by : Jean-Francois Dufour

Download or read book Signaling Pathways in Liver Diseases written by Jean-Francois Dufour and published by John Wiley & Sons. This book was released on 2015-08-31 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signaling Pathways in Liver Diseases, Third Edition again provides hepatologists and hepatology researchers with an expert overview of the complex and novel cellular/extracellular signaling pathways in the liver, and their role in liver diseases. The last few years have seen a great number of developments in this field, which in turn have led to new opportunities for innovative treatments; however, the intricacy of these pathways and their interactions continue to provide a real challenge for clinicians. This outstanding book compiles the emerging knowledge into a single expert resource, cataloguing and organizing it into an accessible and understandable format. With increased focus on the comprehension of cellular mechanisms involved in steatohepatitis, cirrhosis, and liver tumors, which has led to changes in the management of these diseases, this new edition also sees the introduction of exciting new chapters on key emerging areas such as: Autophagy Notch Pathway P13K/PTEN Signaling in Liver Diseases Sirtuins Hepcidin and Iron Epigenetic Regulation of Hepatic Stellate Cells and Liver Fibrosis Oxidative Stress and Signaling in the Liver. Professors Dufour and Clavien have assembled an all-star cast of chapter authors, each of whom has provided clear and appropriate illustrations to reinforce the text, with a key points box offering a concise and handy summary. Self-assessment questions and answers allow the reader to test their own knowledge. Signaling Pathways in Liver Disease, Third Edition is the perfect educational and reference tool to bridge the information exchange between the laboratory, the clinical ward, and the operating room, and an essential tool for the modern-day hepatologist.

The Liver

Author : Irwin M. Arias
Publisher : John Wiley & Sons
ISBN 13 : 1119436826
Total Pages : 1156 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis The Liver by : Irwin M. Arias

Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Drug-Induced Liver Injury

Author :
Publisher : Academic Press
ISBN 13 : 0128173173
Total Pages : 290 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Drug-Induced Liver Injury by :

Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series

Cooperation of Liver Cells in Health and Disease

Author : Z. Kmiec
Publisher : Springer Science & Business Media
ISBN 13 : 3642565530
Total Pages : 154 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Cooperation of Liver Cells in Health and Disease by : Z. Kmiec

Download or read book Cooperation of Liver Cells in Health and Disease written by Z. Kmiec and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.

The Role of Hepatic Sinusoidal Cells in Liver Disease

Author : Paulette Bioulac-Sage
Publisher :
ISBN 13 :
Total Pages : 105 pages
Book Rating : 4.:/5 (355 download)

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Book Synopsis The Role of Hepatic Sinusoidal Cells in Liver Disease by : Paulette Bioulac-Sage

Download or read book The Role of Hepatic Sinusoidal Cells in Liver Disease written by Paulette Bioulac-Sage and published by . This book was released on 1993 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Pathology of Liver Diseases

Author : Satdarshan P. S. Monga
Publisher : Springer Science & Business Media
ISBN 13 : 1441971076
Total Pages : 920 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Molecular Pathology of Liver Diseases by : Satdarshan P. S. Monga

Download or read book Molecular Pathology of Liver Diseases written by Satdarshan P. S. Monga and published by Springer Science & Business Media. This book was released on 2010-12-14 with total page 920 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Pathology of the Liver is extensive, complex and ranges from the understanding the basic molecular mechanisms that dictate everything from liver homeostasis to liver disease. Molecular Pathology of the liver is complicated due to some of the important functions inherent and unique to the Liver, including its innate ability to regenerate and the multitude of functions it plays for the wellbeing of an organism. With all this in mind, Molecular Pathology of Liver Diseases is organized in different sections, which will coherently and cohesively present the molecular basis of hepatic physiology and pathology. The first two sections are key to understanding the liver anatomy and physiology at a cellular level and go on to define the molecular mechanics in various liver cell types. These sections also cover the existing paradigms in liver development, regeneration and growth. The next section is key to understanding the Molecular Pathology unique to liver diseases and associated phenotypes. The final sections are geared towards the existing knowledge of the molecular basis of many common and uncommon liver diseases in both neoplastic and non-neoplastic areas including pathologies associated with intra-hepatic and extra-hepatic biliary tree. Thus, this textbook is a one-stop reference for comprehending the molecular mechanisms of hepatic pathobiology. It is clearly unique in its format, readability and information and thus will be an asset to many in the field of Pathology and other disciplines.

Cells of the Hepatic Sinusoid

Author : Kupffer Cell Foundation
Publisher :
ISBN 13 :
Total Pages : 582 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cells of the Hepatic Sinusoid by : Kupffer Cell Foundation

Download or read book Cells of the Hepatic Sinusoid written by Kupffer Cell Foundation and published by . This book was released on 1991 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Liver Diseases

Author : Florentina Radu-Ionita
Publisher : Springer Nature
ISBN 13 : 3030244326
Total Pages : 806 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Liver Diseases by : Florentina Radu-Ionita

Download or read book Liver Diseases written by Florentina Radu-Ionita and published by Springer Nature. This book was released on 2020-01-10 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an in-depth coverage not only of liver pathology but also of diagnosis of the numerous types of liver disease, placing specific emphasis on current treatments of liver pathology including the most up-to-date information on liver transplantation. The first part of provides an in-depth account of the liver pathology in different conditions such as Hepatits, liver ischaemia reperfusion injury, Lyme disease, cirrhotic cardiomyopathy and hepatocellular carcinoma. The second part provides a comprehensive overview of diagnostic methods. Of particular interest are chapters on the latest techniques in Patient-specific 3D printing and transient elastography (FibroScan). The final part focuses on treatment and provides a step-by step guide to the therapeutic management of liver diseases starting with pharmacological treatment and techniques including surgery and liver transplantation. This is an invaluable book for clinicians, practitioners including academics, scientists/researchers and postgraduates to provide the newest knowledge in the field of liver pathogenesis. It is written by a multidisciplinary team of experts in hepathology, gastroenterology, and surgery especially from liver transplantation.

Textbook of Hepatology

Author : Juan Rodés
Publisher : John Wiley & Sons
ISBN 13 : 1405181516
Total Pages : 2360 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Textbook of Hepatology by : Juan Rodés

Download or read book Textbook of Hepatology written by Juan Rodés and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 2360 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE encyclopedic guide to hepatology – for consultation by clinicians and basic scientists Previously the Oxford Textbook of Clinical Hepatology, this two-volume textbook is now with Blackwell Publishing. It covers basic, clinical and translational science (converting basic science discoveries into the practical applications to benefit people). Edited by ten leading experts in the liver and biliary tract and their diseases, along with outstanding contributions from over 200 international clinicians, this text has global references, evidence and extensive subject matter – giving you the best science and clinical practice discussed by the best authors. It includes unique sections on: Symptoms and signs in liver disease Industrial diseases affecting the liver The effects of diseases of other systems on the liver The effects of liver diseases on other systems It's bigger and more extensive than other books and discusses new areas in more depth such as stem cells, genetics, genomics, proteomics, transplantation, mathematics and much more. Plus, it comes with a fully searchable CD ROM of the entire content. Click here to view a sample chapter on the liver and coagulation

Obesity, Fatty Liver and Liver Cancer

Author : Jun Yu
Publisher : Springer
ISBN 13 : 9811086842
Total Pages : 165 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Obesity, Fatty Liver and Liver Cancer by : Jun Yu

Download or read book Obesity, Fatty Liver and Liver Cancer written by Jun Yu and published by Springer. This book was released on 2018-06-28 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers a state-of-the-art illustration of recent discoveries concerning obesity-related fatty liver diseases and liver cancer. The contents are extensive and comprehensive. It brings important topics in the field all together under one umbrella, from epidemiology and etiology, molecular pathogenesis, cellular biology, epigenetics, immunology, microbiology, animal models to therapeutic approaches and treatments. All the book contributors are leading experts in the field. It will appeal to researchers, clinicians and graduate students in obesity, fatty liver diseases, GI/Liver cancer field. It may also yield benefits for pharmaceutical companies with regard to drug discovery.

Hepatic Immune Response underlying Liver Cirrhosis and Portal Hypertension

Author : Jinhang Gao
Publisher : Frontiers Media SA
ISBN 13 : 2832524923
Total Pages : 250 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Hepatic Immune Response underlying Liver Cirrhosis and Portal Hypertension by : Jinhang Gao

Download or read book Hepatic Immune Response underlying Liver Cirrhosis and Portal Hypertension written by Jinhang Gao and published by Frontiers Media SA. This book was released on 2023-06-02 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Liver Disease in Children

Author : Frederick J. Suchy
Publisher : Cambridge University Press
ISBN 13 : 1108911374
Total Pages : 875 pages
Book Rating : 4.1/5 (89 download)

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Book Synopsis Liver Disease in Children by : Frederick J. Suchy

Download or read book Liver Disease in Children written by Frederick J. Suchy and published by Cambridge University Press. This book was released on 2021-03-18 with total page 875 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver disease in children is increasing in prevalence, placing a huge burden on healthcare systems and often requiring long-term management. Offering an integrative approach to the science and clinical practice of pediatric hepatology, this is the definitive reference text for improved diagnosis and treatment strategies. In the new edition of this authoritative text, chapters have been thoroughly revised in line with major advances in the field, such as recognizing the increased frequency of fatty liver disease, and how genetic testing has the potential to establish earlier diagnoses for a variety of diseases. Disorders covered include cholestasis, metabolic disorders and hepatitis, with their presentation across the spectrum of infancy, childhood and adolescence discussed. The indications and surgical aspects of liver transplant are explained and post-transplant care is described in detail. This is a valuable resource for pediatricians, hepatologists, gastroenterologists and all clinicians involved in the care of children with liver diseases.

Basic and Clinical Hepatology

Author : P. Motta
Publisher : Springer Science & Business Media
ISBN 13 : 940098216X
Total Pages : 245 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Basic and Clinical Hepatology by : P. Motta

Download or read book Basic and Clinical Hepatology written by P. Motta and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The liver has been an organ of mystery for centuries. Slowly but surely its secrets have been disclosed by both basic research and clinically oriented investigators whose current concepts have been brought together in this book by authors from five different countries. Three major groups with many subgroups have made inroads into our better understanding of the liver. The first of these comprises the basic scientists whose study of single hepatocytes may provide the key to comprehension of mechanisms that will lead eventually to improvement in the morbidity and mortality associated with a variety of hepatic disorders. The second group has been concerned with studies in depth of the liver's response to a variety of hormones, drugs, viruses, and infections. Both early and late results are their concern in the diagnosis and treatment of the individual patient. A third group comprises the surgeons who have become increasingly aggressive in the removal of one or more segments of the liver. They have increased the scope of hepatic resection as a result of a better understanding gained from studies of various segments of the liver. They have accepted the term, segmentectomy, and have extended feasible procedures to include trisegmentectomy. Indeed, trans plantation of the liver has been successfully accomplished.

Vascular Disorders of the Liver

Author : Dominique Valla
Publisher : Springer Nature
ISBN 13 : 303082988X
Total Pages : 376 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Vascular Disorders of the Liver by : Dominique Valla

Download or read book Vascular Disorders of the Liver written by Dominique Valla and published by Springer Nature. This book was released on 2021-12-03 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive account on individually rare, but collectively frequent diseases of the liver. In the first part, conditions such as hepatic vascular malformations, ischemic cholangiopathy, hepatic artery occlusion, sinusoidal conditions and Budd-Chiari syndrome are discussed among others. The second part examines the causes of vascular liver disease namely, coagulation disorders, neoplasm disorders, non-malignant blood disorders, systemic diseases and toxins, among others. The unique expertise of the authors, who are all members of the Vascular Liver Disease Disorders Group, an independent network of researchers with a common interest in Vascular Liver Diseases, are merged for an optimal pragmatic and individualized approach. This book is of interest to a broad range of experts, such as hepatologists, internists, radiologists and angiologists.