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Author : David R. Triger
Publisher : Butterworth-Heinemann
ISBN 13 :
Total Pages : 260 pages
Book Rating : 4.3/5 (91 download)
Download or read book Clinical Immunology of the Liver and Gastrointestinal Tract written by David R. Triger and published by Butterworth-Heinemann. This book was released on 1986 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Stephan R. Targan
Publisher : Igaku-Shoin Medical Publishers
ISBN 13 :
Total Pages : 680 pages
Book Rating : 4.3/5 (91 download)
Download or read book Immunology and Immunopathology of the Liver and Gastrointestinal Tract written by Stephan R. Targan and published by Igaku-Shoin Medical Publishers. This book was released on 1990 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Richard Heatley
Publisher : Cambridge University Press
ISBN 13 : 0521445094
Total Pages : 412 pages
Book Rating : 4.5/5 (214 download)
Download or read book Gastrointestinal and Hepatic Immunology written by Richard Heatley and published by Cambridge University Press. This book was released on 1994-10-27 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 1994 volume summarizes basic scientific advances in the area of the gut immune system and the immune abnormalities relevant to gastrointestinal and liver disease.
Author : A. Ferguson
Publisher : Springer Science & Business Media
ISBN 13 : 940116150X
Total Pages : 413 pages
Book Rating : 4.4/5 (11 download)
Download or read book Immunological Aspects of the Liver and Gastrointestinal Tract written by A. Ferguson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: We have been privileged to start our academic careers at the begin ning of the decade in which the immunological roles and hypersensitivity diseases of the gastrointestinal tract and liver have been defined. In the early 1960s IgA was reported to be the main secretory immunoglobulin, immunoblasts were shown to home to the intestinal mucosa and certain serum autoantibodies were described in patients with chronic liver disease. Shortly thereafter IgE and Australia antigen were discovered. Parallel advances in clinical investigation, in particular closed biopsy techniques, facilitated correlation of morphological changes with im munological mechanisms in disease of the gastrointestinal tract and liver. Only 10 years later, the concepts of immunity and hypersensitivity are regularly applied to the pathogenesis, diagnosis, treatment and prog nosis of many chronic diseases in these organs. In designing this book we have attempted to integrate theorectical and clinical immunology as they pertain in 1975; our ultimate aim is aptly described by Brachet as quoted by Professor Paronetto (page 319). We would like to think that this review provides a basis for the next major advances in the fields of gastrointestinal and hepatic immunology. As we see it, the outstanding problem in both sites is how to produce protective immunity without hypersensitivity.
Author : Martin F. Heyworth
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 250 pages
Book Rating : 4.3/5 (91 download)
Download or read book Immunology of the Gastrointestinal Tract and Liver written by Martin F. Heyworth and published by Lippincott Williams & Wilkins. This book was released on 1988 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ralph Wright (M.D.)
Publisher : Hodder Education
ISBN 13 :
Total Pages : 148 pages
Book Rating : 4.3/5 (91 download)
Download or read book Immunology of Gastrointestinal and Liver Disease written by Ralph Wright (M.D.) and published by Hodder Education. This book was released on 1977 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michael P. Manns
Publisher :
ISBN 13 : 9780702021879
Total Pages : 162 pages
Book Rating : 4.0/5 (218 download)
Download or read book Liver and Gastrointestinal Immunology written by Michael P. Manns and published by . This book was released on 1996 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work on liver and gastroenterology covers such topics as the regulation of the mucosal epithelial cell barrier; antigen preservation in the intestinal tract; special features of the intestinal lymphatic system; and the immunopathology of primary biliary cirrhosis.
Author : M. Eric Gershwin
Publisher : Springer Science & Business Media
ISBN 13 : 331902096X
Total Pages : 480 pages
Book Rating : 4.3/5 (19 download)
Download or read book Liver Immunology written by M. Eric Gershwin and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver Immunology: Principles and Practice, Second Edition begins with important information about the epidemiology and mortality of liver disease worldwide. This information is followed by chapters related to basic immunology, application of liver immunology for diagnosis, and several excellent chapters that provide a solid foundation for understanding immune-mediated liver disease, including those associated with the biliary tree. A chapter on non-hepatic manifestations of immune mediated liver disease helps provide context for how these diseases affect the patient overall. In addition, chapters discuss various discrete immunologically-mediated infectious liver disorders including those related to bacteria, parasites, and all of the classic viruses. Chapters on the traditional autoimmune liver diseases -- primary biliary cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis as well as overlap syndrome – are also included. The breadth of this comprehensive second edition is highlighted by chapters on alcoholic liver disease, non-alcoholic fatty liver disease, and drug-induced liver disease, among others. This invaluable new edition ends with a forward-looking view of future directions and how the field might meet the challenge of refractory patients. Developed by a renowned group of authors, Liver Immunology: Principles and Practice, Second Edition will again serve as a comprehensive textbook by providing an excellent overview for this rapidly evolving field. It greatly adds to the understanding of the pathogenesis of these diseases, while also providing novel insights that can be harnessed into helping improve the care of patients afflicted with various immune-mediated diseases. This volume will again be a must-read for clinicians at all levels, investigators and students.
Author :
Publisher :
ISBN 13 :
Total Pages : 7 pages
Book Rating : 4.:/5 (752 download)
Download or read book Immunology of GI and Liver Disease written by and published by . This book was released on 1976 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ralph Wright
Publisher :
ISBN 13 : 9780702012112
Total Pages : 254 pages
Book Rating : 4.0/5 (121 download)
Download or read book Gastrointestinal and Liver Immunology written by Ralph Wright and published by . This book was released on 1987 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : M. Lukás
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387923
Total Pages : 338 pages
Book Rating : 4.3/5 (879 download)
Download or read book Immunological Diseases of Liver and Gut written by M. Lukás and published by Springer Science & Business Media. This book was released on 2004-06-30 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the proceedings of the Falk Symposium No. 135 held in Prague, Czech Republic, on September 12-13, 2003, and is dedicated to the important issue of immunological aspects of diseases of the liver and gut. Without any doubt, immunological pathways are among the most important and universal factors in the pathogenesis of all diseases. Their importance is also constantly increasing, because these principles have been adopted in clinical practice for both diagnostic and therapeutic procedures. Chapters by prominent experts will stimulate new ideas and set the scene for productive discussion on this topic.
Author : H.C. Thomas
Publisher : Springer Science & Business Media
ISBN 13 : 9401114285
Total Pages : 212 pages
Book Rating : 4.4/5 (11 download)
Download or read book Immunology of Liver Disease written by H.C. Thomas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of the immune response in both the pathology of liver disease and in the modulation ofliver injury has been the subject of intense research. This book aims to present the current understanding of the involvement of the immune response in liver disease. The first chapters examine the role of the immune response in viral infections of the liver. These viruses cause hepatitis of varying severity and it is thought that many of the mechanisms responsible for liver cell injury are immunologically mediated. In addition three of these viruses, hepatitic B, C, and D, are associated with persistent infection and chronic liver disease. The role of the immune response in viral persistence is discussed. Further chapters are devoted to the three major autoimmune liver diseases which are thought to be the result of loss of tolerance to autologous liver tissue. There has been much recent research on cellular immune responses in these diseases but knowledge of the immunological processes which lead to the breakdown of tolerance and the mechanisms of tissue damage are limited. Other research has concentrated on the identification of the antigens which are the targets of this immune response. Linkage disequilibrium between MHC alleles and autoimmune diseases has suggested a role for immunogenetic factors.
Author : M. Eric Gershwin
Publisher : S Karger Ag
ISBN 13 : 9783805594462
Total Pages : 303 pages
Book Rating : 4.5/5 (944 download)
Download or read book Falk Liver Conference written by M. Eric Gershwin and published by S Karger Ag. This book was released on 2010 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reprint of 'Digestive Diseases' contains contributions discussing the subject in-depth. 'Digestive Diseases' is a well-respected, international peer-reviewed journal in Gastroenterology. Special topic issues are included in the subscription.
Author : M.P. Manns
Publisher : Springer Science & Business Media
ISBN 13 : 9401140006
Total Pages : 426 pages
Book Rating : 4.4/5 (11 download)
Download or read book Immunology and Liver written by M.P. Manns and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1992, the Falk Symposium No. 70 dealt with the topic `Immunology and Liver'. At that time basic mechanisms of immunology as well as immunopathogenetic mechanisms in viral and autoimmune liver diseases were discussed. Now, 7 years later, the Falk Symposium No. 114, held in Basel, Switzerland, October 20-21 1999 (Part I of the Basel Liver Week 1999), focused on immunology in autoimmune liver diseases. In the first section basic mechanisms of autoimmunity are presented, including the relevance of superantigens and the role of apoptosis. A further topic is the latest developments concerning animal models for autoimmune diseases. Recently the International Autoimmune Hepatitis Group newly defined and reclassified the syndrome of autoimmune hepatitis. Autoimmune hepatitis is now identified and studied in all parts of the world, including Asia and South America. A special variant of autoimmune hepatitis was identified as one organ manifestation of the autoimmune polyendocrine syndrome type 1, a genetic disease caused by mutations in a single transcription factor. Drug- and hepatitis-virus induced immune mediated liver diseases may serve as models for nonhepatic immune mediated disorders. DNA technology has increased our knowledge of the immunogenetic background of autoimmune liver diseases. Among the cholestatic immune mediated liver diseases, significant progress has been made concerning primary biliary cirrhosis, in particular regarding the identification of mitochondrial antigens and the characterisation of the immune reactions directed at them. The involvement of infectious agents in PBC as well as the definition of overlap syndromes is a particular focus for basic and clinical research in this area. Concerning the therapy of autoimmune liver diseases, corticosteroids and azathioprin remain the state of the art for autoimmune hepatitis, while bile acids have become well established in treatment of primary biliary cirrhosis as well as primary sclerosing cholangitis. New drugs in the future will include topical steroids such as budesonide and new immunosuppressive agents like mofetil/mycophenolate. Liver transplantation is the treatment of choice for end stage liver diseases; all autoimmune liver diseases are among the best candidates for liver transplantation. Hopefully, new therapeutic strategies based on the results obtained from experimental models will become everyday clinical practice in the next decade. Therefore this symposium concludes with a discussion.
Author : Ralph Wright
Publisher :
ISBN 13 : 9780608179780
Total Pages : 254 pages
Book Rating : 4.1/5 (797 download)
Download or read book Immunology of GI and Liver Disease written by Ralph Wright and published by . This book was released on 1976 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ralph Wright
Publisher :
ISBN 13 : 9780815193678
Total Pages : pages
Book Rating : 4.1/5 (936 download)
Download or read book Immunology of Gastrointestinal and Liver Disease written by Ralph Wright and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : H.C. Thomas
Publisher : Springer Science & Business Media
ISBN 13 : 3642684467
Total Pages : 338 pages
Book Rating : 4.6/5 (426 download)
Download or read book Immunological Aspects of Liver Disease written by H.C. Thomas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Howard C. Thomas In normal subjects the regulatory apparatus of the immune system permits responses to foreign antigens but suppresses those directed to "self' components. Autoimmune disease occurs as a failure ofthis system either as a result of a primary defect in the regulatory apparatus (primary autoimmunization) or because of a change in the antigenicity of the tissues (secondary autoimmunization). Autoaggressive reactions are characterised by the presence of autoantibodies. When these are directed to membrane displayed antigens (Fig. 1) they are probably of importance in the lysis of hepatocytes. Those directed to cytoplasmic antigens may be useful diagnostically but are of unknown pathogenic significance. When no extrinsic aetiological factor can be identified, the process is assumed to be the result of a failure ofthe regulatory system, allowing the spontaneous expansion of a clone of autoreactive lymphocytes. The defect may be generalised or specific to certain groups of self-antigens and thus the autoimmune disease may be either multi- or unisystemic. The recent development of techniques to enumerate and measure the functional activity of the suppressor lymphocytes which control the effector limbs of the immune system has enabled investigators to test whether the various purported autoimmune diseases do have as their basis a generalised defect in immunoregu lation. Assessment of antigen-specific immunoregulatory function is, however, not yet readily available. liver Membrane I Antigen (LIM) I Liver I HLA, A, B, C, Sensitisation to Specific -;::!IIIL. .
