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Lithium And Manic Depression
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Book Synopsis Pharmacological Treatment of Mental Disorders in Primary Health Care by : World Health Organization
Download or read book Pharmacological Treatment of Mental Disorders in Primary Health Care written by World Health Organization and published by World Health Organization. This book was released on 2009 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual attempts to provide simple, adequate and evidence-based information to health care professionals in primary health care especially in low- and middle-income countries to be able to provide pharmacological treatment to persons with mental disorders. The manual contains basic principles of prescribing followed by chapters on medicines used in psychotic disorders; depressive disorders; bipolar disorders; generalized anxiety and sleep disorders; obsessive compulsive disorders and panic attacks; and alcohol and opioid dependence. The annexes provide information on evidence retrieval, assessment and synthesis and the peer view process.
Book Synopsis The History of Lithium Therapy by : Frederick Neil Johnson
Download or read book The History of Lithium Therapy written by Frederick Neil Johnson and published by Springer. This book was released on 1984-06-18 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mental written by Jaime Lowe and published by Penguin. This book was released on 2017-10-03 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: A riveting memoir and a fascinating investigation of the history, uses, and controversies behind lithium, an essential medication for millions of people struggling with bipolar disorder. It began in Los Angeles in 1993, when Jaime Lowe was just sixteen. She stopped sleeping and eating, and began to hallucinate—demonically cackling Muppets, faces lurking in windows, Michael Jackson delivering messages from the Neverland Underground. Lowe wrote manifestos and math equations in her diary, and drew infographics on her bedroom wall. Eventually, hospitalized and diagnosed as bipolar, she was prescribed a medication that came in the form of three pink pills—lithium. In Mental, Lowe shares and investigates her story of episodic madness, as well as the stability she found while on lithium. She interviews scientists, psychiatrists, and patients to examine how effective lithium really is and how its side effects can be dangerous for long-term users—including Lowe, who after twenty years on the medication suffers from severe kidney damage. Mental is eye-opening and powerful, tackling an illness and drug that has touched millions of lives and yet remains shrouded in social stigma. Now, while she adjusts to a new drug, her pursuit of a stable life continues as does her curiosity about the history and science of the mysterious element that shaped the way she sees the world and allowed her decades of sanity. Lowe travels to the Bolivian salt flats that hold more than half of the world’s lithium reserves, rural America where lithium is mined for batteries, and tolithium spas that are still touted as a tonic to cure all ills. With unflinching honesty and humor, Lowe allows a clear-eyed view into her life, and an arresting inquiry into one of mankind’s oldest medical mysteries.
Book Synopsis Lithium: A Doctor, a Drug, and a Breakthrough by : Walter A. Brown
Download or read book Lithium: A Doctor, a Drug, and a Breakthrough written by Walter A. Brown and published by Liveright Publishing. This book was released on 2019-08-13 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The remarkable untold story of a miracle drug, the forgotten pioneer who discovered it, and the fight to bring lithium to the masses. The DNA double helix, penicillin, the X-ray, insulin—these are routinely cited as some of the most important medical discoveries of the twentieth century. And yet, the 1949 discovery of lithium as a cure for bipolar disorder is perhaps one of the most important—yet largely unsung—breakthroughs of the modern era. In Lithium, Walter Brown, a practicing psychiatrist and professor at Brown, reveals two unlikely success stories: that of John Cade, the physician whose discovery would come to save an untold number of lives and launch a pharmacological revolution, and that of a miraculous metal rescued from decades of stigmatization. From insulin comas and lobotomy to incarceration to exile, Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade’s “Lithium Salts in the Treatment of Psychotic Excitement” described, for the first time, lithium’s astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide. And yet, as Brown shows, it would be decades before lithium would overcome widespread stigmatization as a dangerous substance, and the resistance from the pharmaceutical industry, which had little incentive to promote a naturally occurring drug that could not be patented. With a vivid portrait of the story’s unlikely hero, John Cade, Brown also describes a devoted naturalist who, unlike many modern medical researchers, did not benefit from prestigious research training or big funding sources (Cade’s “laboratory” was the unused pantry of an isolated mental hospital). As Brown shows, however, these humble conditions were the secret to his historic success: Cade was free to follow his own restless curiosity, rather than answer to an external funding source. As Lithium makes tragically clear, medical research—at least in America—has transformed in such a way that serendipitous discoveries like Cade’s are unlikely to occur ever again. Recently described by the New York Times as the “Cinderella” of psychiatric drugs, lithium has saved countless of lives and billions of dollars in healthcare costs. In this revelatory biography of a drug and the man who fought for its discovery, Brown crafts a captivating picture of modern medical history—revealing just how close we came to passing over this extraordinary cure.
Book Synopsis The Science and Practice of Lithium Therapy by : Gin S. Malhi
Download or read book The Science and Practice of Lithium Therapy written by Gin S. Malhi and published by Springer. This book was released on 2016-11-24 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a clear and comprehensive guide to the clinical prescription of lithium that draws upon evidence-based knowledge of its mechanisms of action. The book is divided into two parts, on the science of lithium and the practice of lithium therapy. The former covers aspects such as the properties of the lithium ion, pharmacokinetics and pharmacodynamics, impact on neurotransmission, and gene expression modulation. The section on practice includes discussion of variability in response to lithium, use of lithium in the treatment of bipolar disorders, its value in suicide prevention, administration during pregnancy and in the pediatric age group, and side effects. Lithium is arguably the only true mood stabilizer, and its multifaceted effects across many clinical domains have given rise to a resurgence of interest in recent years, fuelled by both researchers and clinicians. Nevertheless, its use remains constrained by exaggerated concerns about potential side-effects. In reality, lithium is a simple molecule that is relatively straightforward to administer and monitor and has potentially profound benefits at a fraction of the cost of contemporary agents. This book dispels the many myths and concerns that surround its use and will be of interest for clinicians and researchers worldwide, and those that are recipients of lithium therapy.
Book Synopsis Pediatric Bipolar Disorder by : Robert L. Findling
Download or read book Pediatric Bipolar Disorder written by Robert L. Findling and published by CRC Press. This book was released on 2002-10-10 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bipolar disorders were once considered rare in children and adolescents. A growing body of scientific evidence now suggests that they may be more prevalent in this group than previously believed. At the same time, the practitioner faces significant clinical challenges in both the assessment processes and also the implementation of a treatment plan. A paucity of treatment manuals and pharmacological algorithms providing practical guidance makes the task of the clinician even more difficult, despite the fact that more is known about the assessment, neurobiology and treatment of children and adolescents with bipolar disorder than ever before. Written by three distinguished experts, this book conveys to clinicians all the information currently available in this area. They review both the neuroscience and also the integration of rational, practical, pharmacological and psychosocial interventions. Based on what is known, a sound approach to the assessment of these youngsters can be developed. Similarly, available evidence allows practitioners to ground their treatment protocols solidly on scientific knowledge. Concise and authoritative, Pediatric Bipolar Disorders will give the reader a practical approach to both the art and science of providing the best possible clinical care to children and adolescents with the disorder. This book is written primarily for clinical psychiatrists, but will also be of interest to non-specialist doctors and other members of the health care team.
Book Synopsis The Treatment of Bipolar Disorder by : André F. Carvalho
Download or read book The Treatment of Bipolar Disorder written by André F. Carvalho and published by Oxford University Press. This book was released on 2017-03-01 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bipolar disorder is a chronic and debilitating mental illness affecting a significant proportion of the world's population. It is associated with significant impairments in health-related quality of life and psychosocial functioning, and has significant illness-related morbidity and heightened mortality rates due to medical comorbidities and suicide. The management of this disorder requires a complex combination of pharmacological and psychosocial interventions which can be challenging for clinicians. Written by world experts in the field of bipolar disorder, The Treatment of Bipolar Disorder: Integrative Clinical Strategies and Future Directions provides readers with a concise and comprehensive guide to the integrative management of bipolar disorder. This resource contains 31 chapters on the various management choices available, from both established and novel treatment areas, such as psychoeducation, psychotherapeutic interventions, neuromodulatory approaches and novel therapeutic targets. The complexity and diversity of the management choices available makes this a continually evolving field and necessitates forward thinking. By both discussing the current management of bipolar disorder, and the future developments available, this resource provides all clinicians working with patients with bipolar disorder an up-to-date and reflective guide to its management and what the future holds.
Author :American Psychiatric Association Publisher :American Psychiatric Pub ISBN 13 :9780890423226 Total Pages :60 pages Book Rating :4.4/5 (232 download)
Book Synopsis Practice Guideline for the Treatment of Patients with Bipolar Disorder (revision) by : American Psychiatric Association
Download or read book Practice Guideline for the Treatment of Patients with Bipolar Disorder (revision) written by American Psychiatric Association and published by American Psychiatric Pub. This book was released on 2002 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides treatment recommendations for bipolar patients, a review of evidence about bipolar disorder, and states research needs
Download or read book Finding Sanity written by Greg de Moore and published by Allen & Unwin. This book was released on 2016-08-24 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first biography of the ground breaking Australian doctor who discovered the first pharmacological treatment for mental illness. For most of human history, mental illness has been largely untreatable. Sufferers lived their lives - if they survived - in and out of asylums, accumulating life's wreckage around them. In 1948, all that changed when an Australian doctor and recently returned prisoner of war, working alone in a disused kitchen, set about an experimental treatment for one of the scourges of mankind - manic depression, or bipolar disorder. That doctor was John Cade and in that small kitchen he stirred up a miracle. John Cade discovered a treatment that has become the gold standard for bipolar disorder - lithium. It has stopped more people from committing suicide than a thousand help lines. Lithium is the penicillin story of mental health - the first effective medication discovered for the treatment of a mental illness - and it is, without doubt, Australia's greatest mental health story.
Book Synopsis Bipolar, Not So Much: Understanding Your Mood Swings and Depression by : Chris Aiken
Download or read book Bipolar, Not So Much: Understanding Your Mood Swings and Depression written by Chris Aiken and published by W. W. Norton & Company. This book was released on 2017-01-17 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approaching depression as a complex disorder with many different facets rather than all-or-nothing. Now available in paperback with an updated preface. Depression confuses the mind, strips away hope, and causes people to blame themselves for an illness they never asked for. This book presents a revolutionary new understanding of the concept of depression and offers readers skills and strategies to manage it. No longer is this a one-size-fits-all diagnosis, and antidepressants are no longer the one-size-fits-all treatment. Mood disorders are now seen to form a spectrum of problems, from common depression on one end to full bipolar disorder on the other. In between these extremes are multitudes of people who are on the middle of the mood spectrum, and this book is for them. The first part of the book helps readers answer the question, “Where am I on the mood spectrum?” By laying the foundation for understanding this spectrum, Aiken and Phelps highlight the key distinctions that define unipolarity, bipolarity, hypomania, mania, and depression. Readers will be able to discern which definition best fits their experience, and use this understanding to learn which treatment methods will work best. The authors also empower readers to look beyond antidepressants. They walk readers through new medications for the mood spectrum, and offer a guide to non-medication treatments that anyone can use on their own, from diet and lifestyle changes to natural supplements. The book also discusses other innovative technologies that can aid in recovery, including dawn simulators, mood apps, and blue-light filters. This thoughtful and beneficial book will offer readers skills and strategies, as well as hope, in the face of debilitating mental challenges.
Book Synopsis Lithium in Neuropsychiatry by : Michael Bauer
Download or read book Lithium in Neuropsychiatry written by Michael Bauer and published by CRC Press. This book was released on 2006-05-23 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive textbook on the use of lithium in the treatment of mental disorders, this comprehensive work provides an up-to-date analysis of lithium, including: History Clinical applications, including its use for mania, bipolar and schizophrenic disorders Use in special populations, for example in children, the elderly and people with medical conditions The effect on the body and behavior, including neurological, gastrointestinal, cardiovascular and dermatological effects, as well as those relating to the kidneys and thyroid Basic findings in pharmacology, chemistry, transport in the body, pharmacokinetics, signal transduction pathways, immune function, gene regulation. Practical issues, such as guidelines for safe use, discontinuation issues, compliance, intoxication, and economics. Edited by top experts from the International Group for the Study of Lithium Treated Patients (IGSLi), Lithium in Neuropsychiatry: A Comprehensive Guide is a unique and vital resource for psychiatrists, psychopharmacologists, psychotherapists and neuroscientists.
Book Synopsis Biomarkers in Bipolar Disorders by : Rodrigo Machado-Vieira
Download or read book Biomarkers in Bipolar Disorders written by Rodrigo Machado-Vieira and published by Academic Press. This book was released on 2022-01-16 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers in Bipolar Disorders summarizes cutting-edge findings in biomarkers' research, emphasizing the most promising findings, tools and technologies relevant to drug development and personalized medicine. Key findings cover different levels of evidence such as genes, molecules, cells, systems, brain and behavior related to diagnosis (state and trait/endophenotypes), prediction of treatment response and follow-up outcomes, along with the most promising perspectives in each area. Each section includes a comprehensive and focused overview on the state-of-the-art and perspectives. The book concludes with a section on practical applications, encompassing diagnostics development (genetic testing, biomarkers), and new drug development. Edited by Dr. Rodrigo Machado-Vieira and Dr. Jair C. Soares, and contributed by leading experts in the field of biomarker research, this book will be become the leading tool for all researchers and clinicians in Bipolar Disorder. - Describes strategies for the biomarker discovery of relevant proteins differentially expressed in Bipolar Disorder - Presents techniques and main findings in transcriptome research related to CNS synaptic function - Provides an overview on current behavioral strategies and their validity in drug development in Bipolar Disorder - Discusses current genetic findings, integrating tests for treatments leading to personalized treatments
Book Synopsis Gorilla and the Bird by : Zack McDermott
Download or read book Gorilla and the Bird written by Zack McDermott and published by Little, Brown. This book was released on 2017-09-26 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Glorious...one of the best memoirs I've read in years...a tragicomic gem about family, class, race, justice, and the spectacular weirdness of Wichita. [McDermott] can move from barely controlled hilarity to the brink of rage to aching tenderness in a single breath." -- Marya Hornbacher, New York Times Book Review Zack McDermott, a 26-year-old Brooklyn public defender, woke up one morning convinced he was being filmed, Truman Show-style, as part of an audition for a TV pilot. Every passerby was an actor; every car would magically stop for him; everything he saw was a cue from "The Producer" to help inspire the performance of a lifetime. After a manic spree around Manhattan, Zack, who is bipolar, was arrested on a subway platform and admitted to Bellevue Hospital. So begins the story of Zack's freefall into psychosis and his desperate, poignant, often hilarious struggle to claw his way back to sanity. It's a journey that will take him from New York City back to his Kansas roots and to the one person who might be able to save him, his tough, big-hearted Midwestern mother, nicknamed the Bird, whose fierce and steadfast love is the light in Zack's dark world. Before his odyssey is over, Zack will be tackled by guards in mental wards, run naked through cornfields, receive secret messages from the TV, befriend a former Navy Seal and his talking stuffed monkey, and see the Virgin Mary in the whorls of his own back hair. But with the Bird's help, he just might have a shot at pulling through, starting over, and maybe even meeting a partner who can love him back, bipolar and all. Introducing an electrifying new voice, Gorilla and the Bird is a raw and unforgettable account of a young man's unraveling and the relationship that saves him.
Book Synopsis Magnesium in the Central Nervous System by : Robert Vink
Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Book Synopsis Textbook of Psychiatric Epidemiology by : Ming T. Tsuang
Download or read book Textbook of Psychiatric Epidemiology written by Ming T. Tsuang and published by John Wiley & Sons. This book was released on 2011-03-25 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this critically praised textbook continues to provide the most comprehensive overview of the concepts, methods, and research advances in the field; particularly the application of molecular genomics and of neuroimaging. It has been revised and enhanced to capitalize on the strengths of the first and second editions while keeping it up-to-date with the field of psychiatry and epidemiology. This comprehensive publication now includes chapters on experimental epidemiology, gene-environment interactions, the use of case registries, eating disorders, suicide, childhood disorders and immigrant populations, and the epidemiology of a number of childhood disorders. As in the first and second editions, the objective is to provide a comprehensive, easy to understand overview of research methods for the non-specialist. The book is ideal for students of psychiatric epidemiology, psychiatric residents, general psychiatrists, and other mental health professionals. The book features a new editor, Peter Jones, from the University of Cambridge, who joins the successful US team of Ming Tsuang and Mauricio Tohen.
Book Synopsis Neurobiology of Bipolar Disorder by : Joao L. de Quevedo
Download or read book Neurobiology of Bipolar Disorder written by Joao L. de Quevedo and published by Academic Press. This book was released on 2020-11-25 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. - Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations - Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics - Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder
Book Synopsis Current Trends in Lithium and Rubidium Therapy by : G.U. Corsini
Download or read book Current Trends in Lithium and Rubidium Therapy written by G.U. Corsini and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lithium research and therapy needs to be continually re-evaluated on the basis of modern methodological approaches in order to shed new light on the mechanism of action and to improve therapeutic use. This book. based on the proceedings of the "International Meeting on Lithium and Rubidium Therapy" held in Venice from September 30th to October 2nd 1983. is devoted to current trends in the pharmacology and clinical aspects of lithium and of a newly born therapeutic cation. rubidium. The first part of this volume deals with modern trends in behavioural and biochemical approaches to the mechanism of action of lithium. A larger consideration is reserved for lithium therapy from a clinical point of view and includes re-assessment of long-term treatment with regard to serum levels. biological and psychological predictors. side-effects and new therapeutic uses. A smaller section is concerned with some recent clinical studies on rubidium. This volume should be an invaluable aid to all psychiatrists and those who work in the field of research of these pharmacological active metals. G. U. Corsini List of contributors A. ALCIATI L. BELLODI Institute of Clinical Psychiatry Institute of Clinical Psychiatry University of Milan University of Milan Milan Milan Italy Italy R. H. BELMAKER A. AMDISEN Jerusalem Mental Health Center Psychopharmacology Research Unit Ezrath Nashim Aarhus University, Jerusalem Psychiatric Hospital.
