Lipopolysaccharides (LPSs)

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Author :
Publisher : MDPI
ISBN 13 : 3039282565
Total Pages : 390 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Lipopolysaccharides (LPSs) by : Juan M. Tomás

Download or read book Lipopolysaccharides (LPSs) written by Juan M. Tomás and published by MDPI. This book was released on 2020-01-24 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cytoplasm of Gram-negative bacteria is bound by three layers: an inner membrane, a layer of peptidoglycan, and an outer membrane. The outer membrane is an asymmetric lipidic bilayer, with phospholipids on its inner surface and lipopolysaccharides (LPSs) on the outside, with the latter being the major component of the outer leaflet and covering nearly three-quarters of the total outer cell surface. All LPSs possess the same general chemical architecture independently of bacterial activity (pathogenic, symbiotic, commensal), ecological niche (human, animal, soil, plant, water), or growth conditions. Endotoxins are large amphiphilic molecules consisting of a hydrophilic polysaccharide component and a covalently bound hydrophobic and highly conserved lipid component, termed lipid A (the endotoxin subunit). The polysaccharide component can be divided into two subdomains: the internal and conserved core region as well as the more external and highly variable O-specific chain, also referred to as the O-antigen due to its immunogenic properties. LPSs are endotoxins, one of the most potent class of activators of the mammalian immune system; they can be released from cell surfaces of bacteria during multiplication, lysis, and death. LPS can act through its biological center (lipid A component) on various cell types, of which macrophages and monocytes are the most important.

Bacterial Endotoxic Lipopolysaccharides

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Author :
Publisher : CRC Press
ISBN 13 : 9780849367885
Total Pages : 484 pages
Book Rating : 4.3/5 (678 download)

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Book Synopsis Bacterial Endotoxic Lipopolysaccharides by : David C. Morrison

Download or read book Bacterial Endotoxic Lipopolysaccharides written by David C. Morrison and published by CRC Press. This book was released on 1992-09-11 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial Endotoxic Lipopolysaccharides provides an up-to-date, two-volume review of the latest information regarding bacterial lipopolysaccharide structure and activities. These volumes cover the biochemistry, pharmacology, and pathophysiologic properties of endotoxins. The volumes also thoroughly discuss the strengths and weaknesses of new therapies for septic shock that are based on an immunological attack on endotoxins and the cytokines induced by endotoxins. All scientists involved in endotoxin research, clinical infectious disease specialists, and medical students interested in the pathogenesis of septic shock will find Bacterial Endotoxic Lipopolysaccharides invaluable as a reference resource.

Lipopolysaccharide Transport

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Author :
Publisher : Springer Nature
ISBN 13 : 1071625810
Total Pages : 288 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Lipopolysaccharide Transport by : Paola Sperandeo

Download or read book Lipopolysaccharide Transport written by Paola Sperandeo and published by Springer Nature. This book was released on 2022-09-24 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides the most widely used protocols and techniques employed in lipopolysaccharide( LPS) transport studies. Chapters detail identification and analysis of essential genes and crucial mutations in LPS transport-related genes, LPS profile determination, LPS chemical analysis, protein-LPS interaction, and LPS visualization. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Lipopolysaccharide Transport: Methods and Protocols aims to deliver an overview on the multidisciplinary study of LPS transport and to identify new and innovative antibacterial strategies.

Lipopolysaccharides—Advances in Research and Application: 2012 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481610600
Total Pages : 68 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Lipopolysaccharides—Advances in Research and Application: 2012 Edition by :

Download or read book Lipopolysaccharides—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipopolysaccharides—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Lipopolysaccharides in a concise format. The editors have built Lipopolysaccharides—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Lipopolysaccharides in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Lipopolysaccharides—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Endotoxin

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Publisher : Springer Science & Business Media
ISBN 13 : 1475751400
Total Pages : 689 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Endotoxin by : H. Friedman

Download or read book Endotoxin written by H. Friedman and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 689 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is based on the proceedings of the International Symposium on Bacterial Endotoxins held in Japan. May 11-14. 1988 and sponsored by the International Endotoxin Society and the International Society for Immuno pharmacology. Speakers and participants of this symposium provided new information concerning fundamental and clinical aspects of endotoxin research conducted over the last half decade or so. Advances have been made in understanding the structure and nature of endotoxin molecules and their effects on a wide variety of both cellular and subcellular aspects, of immunity. metabolism and physiology. both in vivo and in vitro. Endotoxins are constituents of gram negative bacteria. Since their original discovery in the nineteenth century. many laboratories studied their chemical composition. their physico- and immunochemica1 properties. as well as their pharmacological and physiological effects on the host. Much is now known about the chemical structure of the endotoxins. There is also a grow ing body of information concerning the multiple effects of endotoxins on the host including immune mechanisms. Some effects have been found to be benefi cial to the host and endotoxins are being used more frequently to induce important mediators of immunity as well as increasing resistance against infections by many microorganisms as well as inhibiting growth of tumors in experimental animal models and in man.

Bacterial Pathogenesis

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1588297403
Total Pages : 314 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis Bacterial Pathogenesis by : Frank R. DeLeo

Download or read book Bacterial Pathogenesis written by Frank R. DeLeo and published by Springer Science & Business Media. This book was released on 2008-01-31 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial infections affect world health today as a leading cause of morbidity and mortality. This book presents in-depth methods and state-of-the-art protocols for investigating specific mechanisms of pathogenesis for a wide range of bacteria. Written by experts in the field, this invaluable collection includes protocols to study host-pathogen interactions, animal models of infection, and novel approaches to identifying therapeutic targets designed to control infections.

New edge of antibiotic development: antimicrobial peptides and corresponding resistance

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Author :
Publisher : Frontiers E-books
ISBN 13 : 2889193012
Total Pages : 145 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis New edge of antibiotic development: antimicrobial peptides and corresponding resistance by : Octavio L. Franco

Download or read book New edge of antibiotic development: antimicrobial peptides and corresponding resistance written by Octavio L. Franco and published by Frontiers E-books. This book was released on 2014-09-26 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial peptides, commonly isolated from several organisms, have been considered part of innate immune system and also as potential antimicrobial drugs. Besides its antimicrobial activity, some AMPs also have antifungal activity, inmmunomodulatory and antitumural activities. Lately not only nature has become a source of AMPs. Besides isolation of natural organisms, antimicrobial peptides might be improved or created using computational tools. This opens even more this so amazing field by creating infinite novel and remarkable possibilities. Overall the current issue highlights the relevance of such Research Topic with perspectives to develop entirely new molecules with vast application within health and agricultural field with higher affinity for its target with concomitant reduction of side effects.

Desk Encyclopedia of Microbiology

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Author :
Publisher : Elsevier
ISBN 13 : 008047246X
Total Pages : 1176 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Desk Encyclopedia of Microbiology by : Moselio Schaechter

Download or read book Desk Encyclopedia of Microbiology written by Moselio Schaechter and published by Elsevier. This book was released on 2003-12-11 with total page 1176 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Desk Encyclopedia of Microbiology aims to provide an affordable and ready access to a large variety of microbiological topics within one set of covers. This handy desk-top reference brings together an outstanding collection of work by the top scientists in the field. Covering topics ranging from the basic science of microbiology to the current "hot" topics in the field.* Provides a broad, easily accessible perspective on a wide range of microbiological topics* A synthesis of the broadest topics from the comprehensive and multi-volumed Encyclopedia of Microbiology, Second Edition * Helpful resource in preparing for lectures, writing reports, or drafting grant applications

Endotoxin Detection and Control in Pharma, Limulus, and Mammalian Systems

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Author :
Publisher : Springer
ISBN 13 : 3030171485
Total Pages : 865 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Endotoxin Detection and Control in Pharma, Limulus, and Mammalian Systems by : Kevin L. Williams

Download or read book Endotoxin Detection and Control in Pharma, Limulus, and Mammalian Systems written by Kevin L. Williams and published by Springer. This book was released on 2019-07-24 with total page 865 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endotoxin detection and control is a dynamic area of applied science that touches a vast number of complex subjects. The intersection of test activities includes the use of an ancient blood system from an odd “living fossil” (Limulus). It is used to detect remnants of the most primitive and destructive forms of life (prokaryotes) as contaminants of complex modern systems (mammalian and Pharma). Recent challenges in the field include those associated with the application of traditional methods to new types of molecules and manufacturing processes. The advent of “at will” production of biologics in lieu of harvesting animal proteins has revolutionized the treatment of disease. While the fruits of the biotechnology revolution are widely acknowledged, the realization of the differences in the means of production and changes in the manner of control of potential impurities and contaminants in regard to the new versus the old are less widely appreciated. Endotoxin as an ancient, dynamic interface between lifeforms, provides a singular perspective from which to view the parallel development of ancient and modern organisms as well as the progress of man in deciphering the complexity of their interactions in his efforts to overcome disease.

The Rhizobiaceae

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9401150605
Total Pages : 576 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis The Rhizobiaceae by : Herman P. Spaink

Download or read book The Rhizobiaceae written by Herman P. Spaink and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Rhizobiaceae, Molecular Biology of Model Plant-Associated Bacteria. This book gives a comprehensive overview on our present molecular biological knowledge about the Rhizobiaceae, which currently can be called the best-studied family of soil bacteria. For many centuries they have attracted the attention of scientists because of their capacity to associate with plants and as a consequence also to specifically modify plant development. Some of these associations are beneficial for the plant, as is the case for the Rhizobiaceae subgroups collectively called rhizobia, which are able to fix nitrogen in a symbiosis with the plant hosts. This symbiosis results in the fonnation of root or stem nodules, as illustrated on the front cover. In contrast, several Rhizobiaceae subgroups can negatively affect plant development and evoke plant diseases. Examples are Agrobacterium tumefaciens andA. rhizogenes which induce the formation of crown galls or hairy roots on the stems of their host plants, respectively (bottom panels on front cover). In addition to the obvious importance of studies on the Rhizobiaceae for agronomy, this research field has resulted in the discovery of many fundamental scientific principles of general interest, which are highlighted in this book. To mention three examples: (i) the discovery of DNA transfer of A.

The Role of Complement in Health and Disease

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889631591
Total Pages : 631 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis The Role of Complement in Health and Disease by : Maciej Cedzyński

Download or read book The Role of Complement in Health and Disease written by Maciej Cedzyński and published by Frontiers Media SA. This book was released on 2019-11-18 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microbial Glycobiology

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Author :
Publisher : Elsevier
ISBN 13 : 0080923240
Total Pages : 1037 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Microbial Glycobiology by : Anthony P Moran

Download or read book Microbial Glycobiology written by Anthony P Moran and published by Elsevier. This book was released on 2009-10-01 with total page 1037 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents in an easy-to-read format a summary of the important central aspects of microbial glycobiology, i.e. the study of carbohydrates as related to the biology of microorganisms. Microbial glycobiology represents a multidisciplinary and emerging area with implications for a range of basic and applied research fields, as well as having industrial, medical and biotechnological implications. - Individual chapters provided by leading international scientists in the field yield insightful, concise and stimulating reviews - Provides researchers with an overview and synthesis of the latest research - Each chapter begins with a brief 200 word Summary/Abstract detailing the topic and focus of the chapter, as well as the concepts to be addressed - Allows researchers to see at a glance what each chapter will cover - Each chapter includes a Research Focus Box - Identifies important problems that still need to be solved and areas that require further investigation

Endotoxins—Advances in Research and Application: 2013 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481675346
Total Pages : 170 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Endotoxins—Advances in Research and Application: 2013 Edition by :

Download or read book Endotoxins—Advances in Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endotoxins—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built Endotoxins—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Endotoxins—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Encyclopedia of Chromatography

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Publisher : CRC Press
ISBN 13 : 1439870675
Total Pages : 2968 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Encyclopedia of Chromatography by : Jack Cazes

Download or read book Encyclopedia of Chromatography written by Jack Cazes and published by CRC Press. This book was released on 2009-10-12 with total page 2968 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and expanded, this third edition offers illustrative tables and figures to clarify technical points in the articles and provides a valuable, reader-friendly reference for all those who employ chromatographic methods for analysis of complex mixtures of substances. An authoritative source of information, this introductory guide to specific chromatographic techniques and theory discusses the relevant science and technology, offering key references for analyzing specific chemicals and applications in industry and focusing on emerging technologies and uses.

Biological Nitrogen Fixation: Towards Poverty Alleviation through Sustainable Agriculture

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1402082525
Total Pages : 353 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Biological Nitrogen Fixation: Towards Poverty Alleviation through Sustainable Agriculture by : Felix D. Dakora

Download or read book Biological Nitrogen Fixation: Towards Poverty Alleviation through Sustainable Agriculture written by Felix D. Dakora and published by Springer Science & Business Media. This book was released on 2008-06-26 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poverty is a severe problem in Africa, Asia, South America and even in pockets of the developed world. Addressing poverty alleviation via the expanded use of biological nitrogen fixation in agriculture was the theme of the 15th International Congress on Nitrogen Fixation. Because nitrogen-fixation research is multidisciplinary, exploiting its benefits for agriculture and environmental protection has continued to attract research by diverse groups of scientists, including chemists, biochemists, plant physiologists, evolutionary biologists, ecologists, agricultural scientists, extension agents, and inoculant producers. The 15th International Congress on Nitrogen Fixation was held jointly with the 12th International Conference of the African Association for Biological Nitrogen Fixation. This joint Congress was hosted in South Africa at the Cape Town International Conv- tion Centre, 21–26 January 2007, and was attended by about 200 registered participants from 41 countries world-wide. During the Congress, some 100 oral and approximately 80 poster papers were presented. The wide range of topics covered and the theme of the Congress justifies this book’s title, Nitrogen Fixation: Applications to Poverty Alleviation.

Handbook of Microbiome and Gut-Brain-Axis in Alzheimer’s Disease

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Author :
Publisher : IOS Press
ISBN 13 : 164368289X
Total Pages : 732 pages
Book Rating : 4.6/5 (436 download)

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Book Synopsis Handbook of Microbiome and Gut-Brain-Axis in Alzheimer’s Disease by : G.M. Pasinetti

Download or read book Handbook of Microbiome and Gut-Brain-Axis in Alzheimer’s Disease written by G.M. Pasinetti and published by IOS Press. This book was released on 2022-07-05 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite being confined to the gastrointestinal tract, the gut microbiome has a wide impact on human physiology, supplementing its host’s biochemistry in a complex symbiotic relationship. Research in the field has evolved rapidly in the last decade, and we are now developing a better understanding of how our gut microbiome can influence our immune systems, metabolism, neurological signaling, and perhaps most unexpectedly, our brains; a phenomenon described as the gut-brain-axis. This book, ‘Handbook of Microbiome and Gut-Brain-Axis in Alzheimer’s Disease’, sets out to explore the complex role of the microbiome with regard to Alzheimer’s disease (AD). The microbiome is a critical and often overlooked aspect of immunity, which in turn plays a role in cognition. The book presents current research into the gut microbiota and its far-reaching impacts on cognitive function and neurodegeneration. Interventions, including probiotic supplementation, fecal transfer, and supplementation with microbial metabolites, are discussed, as is the use of certain probiotics to study the effects of the gut microbiota on behavior and cognitive function, and as potential therapeutics for AD. Other topics covered include the influence of the gut and oral microbiota on immune inflammatory signals: cytokines, neuroendocrine hormones, bacterial components, neuroactive molecules, and microbial metabolites. The book is divided into four sections, each covering a research area pertinent to the gut-brain-axis and its relationship with cognitive function and AD. It will be of interest to all those whose work includes the study and understanding of these complex, multi-variable biological mechanisms, particularly in the context of cognitive function and AD. The cover shows a color edited MRI image of a sagittal section of a neurological control brain of Dr. Giulio Maria Pasinetti.

Nitrogen Fixation: From Molecules to Crop Productivity

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0306476150
Total Pages : 661 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Nitrogen Fixation: From Molecules to Crop Productivity by : Fabio O. Pedrosa

Download or read book Nitrogen Fixation: From Molecules to Crop Productivity written by Fabio O. Pedrosa and published by Springer Science & Business Media. This book was released on 2006-04-18 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: These proceedings bring together diverse disciplines that study nitrogen fixation and describe the most recent advances made in various fields: chemists are now studying FeMoco, the active site of nitrogenase in non-protein surroundings, and have refined the crystal structure of the enzyme to 1.6 angstroms.