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Lipid Polymorphism And Membrane Properties
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Book Synopsis Lipid Polymorphism and Membrane Properties by :
Download or read book Lipid Polymorphism and Membrane Properties written by and published by Academic Press. This book was released on 1997-10-02 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major lipid components of biological membranes can undergo many diverse and fascinating morphological rearrangements. Studies of these diverse phases and the manner in which they are formed tends to alter the properties of ordinary bilayer membranes. This book examines the structural and biological roles of lipids forming non-lamellar structures. Key Features* Characterization of non-lamellar structures * Protein activity and membrane properties* Analysis of membrane fusion* Affect of non-lamellar forming lipids on biological systems
Book Synopsis Methods in Membrane Lipids by : Alex M. Dopico
Download or read book Methods in Membrane Lipids written by Alex M. Dopico and published by Springer Science & Business Media. This book was released on 2007-08-30 with total page 1265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a compendium of methodologies for the study of membrane lipids, varying from traditional lab bench experimentation to computer simulation and theoretical models. The volume provides a comprehensive set of techniques for studying membrane lipids with a strong biophysical emphasis. It compares the various available techniques including the pros and cons as seen by the experts.
Book Synopsis Structural and Dynamic Properties of Lipids and Membranes by : Peter J. Quinn
Download or read book Structural and Dynamic Properties of Lipids and Membranes written by Peter J. Quinn and published by Portland Press, London. This book was released on 1992 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work contains an in-depth account of the application of a range of biophysical methods to characterize the structure of lipids and membranes. Topics covered include non bilayer lipid phases, infrared studies of membrane proteins, and biomembrane technologies.
Book Synopsis Structure and Dynamics of Membranes by : R. Lipowsky
Download or read book Structure and Dynamics of Membranes written by R. Lipowsky and published by Elsevier. This book was released on 1995-06-15 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateralphase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes withpolymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process ofcontact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned aboutthe interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.
Book Synopsis Biochemistry of Lipids, Lipoproteins and Membranes by : Dennis E. Vance
Download or read book Biochemistry of Lipids, Lipoproteins and Membranes written by Dennis E. Vance and published by Elsevier. This book was released on 1996-08-06 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the third edition of this advanced textbook, written with two major objectives in mind. One is to provide an advanced textbook covering the major areas in the fields of lipid, lipoprotein, and membrane biochemistry, and molecular biology. The second objective is to provide a clear summary of these research areas for scientists presently working in these fields. The volume provides the basis for an advanced course for students in the biochemistry of lipids, lipoproteins and membranes. The book will satisfy the need for a general reference and review book for scientists studying lipids, proteins and membranes. Excellent up-to-date reviews are available on the various topics covered. A current, readable, and critical summary of these areas of research, it will allow scientists to become familiar with recent developments related to their own research interests, and will help clinical researchers and medical students keep abreast of developments in basic science that are important for subsequent clinical advances.
Book Synopsis Modulation of Membrane Lipid Polymorphism by : Cees Van Echteld
Download or read book Modulation of Membrane Lipid Polymorphism written by Cees Van Echteld and published by . This book was released on 1982 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Drug–biomembrane interaction studies by : A. Wiśniewska-Becker
Download or read book Drug–biomembrane interaction studies written by A. Wiśniewska-Becker and published by Elsevier Inc. Chapters. This book was released on 2013-10-31 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological membranes consisting of two main components, lipids and proteins, have many important functions in cells. Membrane structure, physical and chemical properties of lipids and proteins, and interactions between them determine membrane functions such as the barrier separating a cell from its environment, selective transport, cell recognition, signalling and compartmentalization of cellular processes. To investigate membrane structure and dynamics, and the interactions between membrane components on a molecular level, simplified artificial models of biological membranes have been developed. Various biophysical techniques are used with these models to study membrane properties and their changes under different environmental factors. This chapter describes common membrane models and some of their applications. There are two groups of models: vesicular models (micelles, bicelles and liposomes) and planar ones (lipid monolayers, supported lipid bilayers, black lipid membranes). The advantages and disadvantages of both types are discussed as well as their usefulness for particular biophysical techniques.
Book Synopsis Biological Soft Matter by : Corinne Nardin
Download or read book Biological Soft Matter written by Corinne Nardin and published by John Wiley & Sons. This book was released on 2021-04-06 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Soft Matter Explore a comprehensive, one-stop reference on biological soft matter written and edited by leading voices in the field Biological Soft Matter: Fundamentals, Properties and Applications delivers a unique and indispensable compilation of up-to-date knowledge and material on biological soft matter. The book presents a thorough overview about biological soft matter, beginning with different substance classes, including proteins, nucleic acids, lipids, and polysaccharides. It goes on to describe a variety of superstructures and aggregated and how they are formed by self-assembly processes like protein folding or crystallization. The distinguished editors have included materials with a special emphasis on macromolecular assembly, including how it applies to lipid membranes, and proteins fibrillization. Biological Soft Matter is a crucial resource for anyone working in the field, compiling information about all important substance classes and their respective roles in forming superstructures. The book is ideal for beginners and experts alike and makes the perfect guide for chemists, physicists, and life scientists with an interest in the area. Readers will also benefit from the inclusion of: An introduction to DNA nano-engineering and DNA-driven nanoparticle assembly Explorations of polysaccharides and glycoproteins, engineered biopolymers, and engineered hydrogels Discussions of macromolecular assemblies, including liquid membranes and small molecule inhibitors for amyloid aggregation A treatment of inorganic nanomaterials as promoters and inhibitors of amyloid fibril formation An examination of a wide variety of natural and artificial polymers Perfect for materials scientists, biochemists, polymer chemists, and protein chemists, Biological Soft Matter: Fundamentals, Properties and Applications will also earn a place in the libraries of biophysicists and physical chemists seeking a one-stop reference summarizing the rapidly evolving topic of biological soft matter.
Book Synopsis Life - As a Matter of Fat by : Ole G. Mouritsen
Download or read book Life - As a Matter of Fat written by Ole G. Mouritsen and published by Springer Science & Business Media. This book was released on 2005-10-24 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a multi-disciplinary perspective on the physics of life and the particular role played by lipids and the lipid-bilayer component of cell membranes. Emphasizes the physical properties of lipid membranes seen as soft and molecularly structured interfaces. By combining and synthesizing insights obtained from a variety of recent studies, an attempt is made to clarify what membrane structure is and how it can be quantitatively described. Shows how biological function mediated by membranes is controlled by lipid membrane structure and organization on length scales ranging from the size of the individual molecule, across molecular assemblies of proteins and lipid domains in the range of nanometers, to the size of whole cells. Applications of lipids in nano-technology and biomedicine are also described.
Book Synopsis Crystallization of Lipids by : Kiyotaka Sato
Download or read book Crystallization of Lipids written by Kiyotaka Sato and published by John Wiley & Sons. This book was released on 2018-04-23 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative reference that contains the most up-to-date information knowledge, approaches, and applications of lipid crystals Crystallization of Lipids is a comprehensive resource that offers the most current and emerging knowledge, techniques and applications of lipid crystals. With contributions from noted experts in the field, the text covers the basic research of polymorphic structures, molecular interactions, nucleation and crystal growth and crystal network formation of lipid crystals which comprise main functional materials employed in food, cosmetic and pharmaceutical industry. The authors highlight trans-fat alternative and saturated-fat reduction technology to lipid crystallization. These two issues are the most significant challenges in the edible-application technology of lipids, and a key solution is lipid crystallization. The text focuses on the crystallization processes of lipids under various external influences of thermal fluctuation, ultrasound irradiation, shear, emulsification and additives. Designed to be practical, the book’s information can be applied to realistic applications of lipids to foods, cosmetic and pharmaceuticals. This authoritative and up-to-date guide: Highlights cutting-edge research tools designed to help analyse lipid crystallization with the most current and the conventional techniques Offers a thorough review of the information, techniques and applications of lipid crystals Includes contributions from noted experts in the field of lipid crystals Presents cutting-edge information on the topics of trans-fat alterative and saturated-fat reduction technology Written for research and development technologists as well as academics, this important resource contains research on lipid crystals which comprise the main functional materials employed in food, cosmetic and pharmaceutical industry.
Book Synopsis Bilayer Lipid Membranes. Structure and Mechanical Properties by : Tibor Hianik
Download or read book Bilayer Lipid Membranes. Structure and Mechanical Properties written by Tibor Hianik and published by Springer Science & Business Media. This book was released on 1995-08-31 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Bilayer Lipid Membranes. Structure and Mechanical Properties the authors use new methods of measurement, which they have themselves developed, to present an analysis of the relation between membrane structure and viscoelastic properties, in particular in the transversal direction. Hianik and Passechnik's approach is fundamentally different from the usual one, in that they analyze lipid bilayer dynamics during various modes of deformation, arriving at a new, `three-layer' model that accounts for the great heterogeneity of biomembranes. The macroscopic parameters of membranes have been measured using a wide variety of methods, leading to a discussion of the correlations between the parameters. There is also an extensive discussion of the dynamic changes in mechanical properties of lipid bilayers in the course of conformational transition of integral proteins. During the conformational changes of proteins, the structure of a bilayer undergoes a transition, reaching a new, stable membrane state. The book is the first to present a comprehensive analysis of long-distance interaction in lipid bilayers and of molecular mechanisms of mechanoreception. Audience: Scientists and graduate students working in biophysics, membranology, physiology, medicine, pharmacology, bioelectronics, electrochemistry, and colloid chemistry.
Book Synopsis Lipid-Protein Interactions by : Jörg H. Kleinschmidt
Download or read book Lipid-Protein Interactions written by Jörg H. Kleinschmidt and published by Humana Press. This book was released on 2013-02-14 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological membranes are the essential structuring elements of all living cells. Many enzymatic reactions take place at the membrane-water interface. To gain detailed insight into membrane properties, it is therefore of great importance to understand the complex nature of the interactions of membrane proteins with lipids. Lipid-Protein Interactions: Methods and Protocols provides a selection of protocols to examine protein-lipid interactions, membrane and membrane protein structure, how membrane proteins affect lipids and how they are in turn affected by the lipid bilayer and lipid properties. The methods described here are all actively used, complementary, and necessary to obtain comprehensive information about membrane structure and function. They include label-free approaches, imaging techniques and spectroscopic methodologies. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Lipid-Protein Interactions: Methods and Protocols seeks to serve both professional and novices with its wide range of the methods frequently used in this area of research.
Book Synopsis The Enzymes of Biological Membranes by : A.N. Martonosi
Download or read book The Enzymes of Biological Membranes written by A.N. Martonosi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the first edition of The Enzymes of Biological Membranes, published in four volumes in 1976, we collected the mass of widely scattered information on membrane-linked enzymes and metabolic processes up to about 1975. This was a period of transition from the romantic phase of membrane biochemistry, preoccupied with conceptual developments and the general properties of membranes, to an era of mounting interest in the specific properties of membrane-linked enzymes analyzed from the viewpoints of modem enzymology. The level of sophistication in various areas of membrane research varied widely; the structures of cytochrome c and cytochrome b5 were known to atomic detail, while the majority of membrane-linked enzymes had not even been isolated. In the intervening eight years our knowledge of membrane-linked enzymes ex panded beyond the wildest expectations. The purpose of the second edition of The Enzymes of Biological Membranes is to record these developments. The first volume describes the physical and chemical techniques used in the analysis of the structure and dynamics of biological membranes. In the second volume the enzymes and met abolic systems that participate in the biosynthesis of cell and membrane components are discussed. The third and fourth volumes review recent developments in active transport, oxidative phosphorylation and photosynthesis.
Book Synopsis Manual on Membrane Lipids by : Rajendra Prasad
Download or read book Manual on Membrane Lipids written by Rajendra Prasad and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although previously thought to be merely passive structural components, membrane lipids have recently been found to be actively involved in cellular transport and signal transduction processes. Clear protocols for the study of membrane lipid properties, cellular transport or signal transduction are presented in this manual. Following a short introduction to membrane lipids, techniques for the isolation and extraction of membrane fractions, the analysis of the lipid composition, lipid turnover, and the involvement in signal transduction as well as the preparation of liposomes are described.
Book Synopsis Membrane Lipid Properties and Membrane Function by : John Robert Silvius
Download or read book Membrane Lipid Properties and Membrane Function written by John Robert Silvius and published by . This book was released on 1979 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aims of this work were twofold: first, to generate a biologi cal membrane system in which the lipid fatty acyl composition can be var ied essentially at will, and to study the relationship of lipid proper ties to membrane function in such a system, and secondly, to synthesize and characterize some novel phospholipids which provide valuable model systems whose behavior is relevant to that of the lipids in the biologi cal membrane studied. Toward the former objective, I have developed a simple method for converting the simple cell wall-less prokaryote Acholeplasma laidlawii B into a total fatty acid auxotroph, using avidin to completely inhibit de novo fatty acid synthesis and chain elongation kn vivo . Cells thus treated can grow well when any of a wide variety of fatty acids are add ed to the culture medium, and if a single fatty acid is added, the cells incorporate it into their membrane lipids to the extent of 95+% of the total lipid acyl chains if the fatty acid can support cell growth. The cellular growth-supporting ability of a fatty acid appears to rest on its physical and not its metabolic properties. 'Fatty acid-homogeneous' membranes or membrane lipids, obtained from cells grown with avidin plus any of a number of single fatty acids which are good growth substrates, exhibit a markedly sharper lipid phase transition by differential ther mal analysis than do normal membranes or membrane lipids, which have a heterogeneous fatty acyl composition. The protein and lipid head-group composition of fatty acid-homogeneous membranes varies somewhat depend ing on the nature of the lipid acyl chains, but a variety of experiments indicate that such variations are unlikely to produce changes of a qualitative nature in the physical behavior of the membrane lipids. The potential for manipulation of lipid fatty acyl chains and physical pro perties in the A. laidlawii B membrane has been used to study the physi cal basis of the membrane lipid effects on the temperature dependence of a membrane enzyme activity, the (Na + ,Mg 2 +)-ATPase, which appears to func tion as an osmoregulatory cation pump jui vivo . My results, analyzed in the light of an extensive theoretical analysis of Arrhenius plot behavi or, suggest that the ATPase's catalytic activity is not altered by changes in the lipids around it so long as they are in the liquid-crys talline state, but that a membrane lipid phase transition occurring on cooling the membrane can cause the boundary lipids of the ATPase to en ter a 'gel-like' state and thereby to inactivate the enzyme. Working toward the second objective noted above, that of develop ing and characterizing good pure-lipid model systems for the fatty acid- homogeneous A. laidlawii B membrane, I synthesized a number of branched- chain, odd-chain saturated, monounsaturated and cyclopropane fatty acids and their phosphatidylcholine (PC) derivatives. I then characterized the thermotropic behavior of the fully hydrated PC's by differential thermal analysis. By studying the effect of acyl chain length and struc ture on the thermotropic behavior of hydrated diacyl PC's, I have been able to draw various conclusions regarding the nature of the acyl chain packing in the gel state and regarding the function of various types of methyl-branched and alicyclic lipid acyl chains in membranes. Finally, I have shown that the gel-to-liquid-crystalline phase transition tem peratures of pure PC's and of A. laidlawii B membrane lipids of like fat ty acyl composition correlate very well, indicating that the lipid acyl chain interactions in the two systems are fundamentally similar and that the former lipid system is in fact a good model for the biological membrane.
Book Synopsis Lipid Bilayers by : M. Ashrafuzzaman
Download or read book Lipid Bilayers written by M. Ashrafuzzaman and published by . This book was released on 2019-11-05 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book âLipid Bilayers: Properties, Behavior and Interactions' provides a broad overview of an important biological system âcell membrane'. The cell is the powerhouse where processes of life are controlled. Cell membranes consist of lipid bilayers that make biological boundaries. The bilayer participates in determining most of the cell-based uptakes of materials, exchanging of information between both sides and ensuring helping vital biological processes to continue. We have focused specifically on an understanding of various aspects of lipid membrane bilayers. The book is focused on a detailed description of the diverse mechanisms and phenomena associated with membranes. Lipid bilayers exist in various parts of the cell, namely, across the plasma membrane, mitochondrial membrane, and nuclear membrane. While exploring lipid bilayers we shall, therefore, need to consider structures and functions of various sections of biological cells. Besides spectroscopic observations and electrical measurements of membrane bilayers, we address here the phenomena of coexistence and independent existence of different membrane components using various theoretical and experimental methodologies popularly used in biology, physics, mathematics, chemistry, biomedical engineering, and general medical sciences. The focus has been made on explaining diverse mechanisms that play crucial roles in molecular level in the construction of lipid bilayers and maintaining the relevant biological functions. This book will be helpful for readers who want to understand biological processes by applying both simple observations and fundamental scientific analysis. It provides a deep understanding of the causes and effects of molecular processes inside lipid bilayer membranes. A group of eminent scientists from around the globe contributed chapters focusing on different aspects. Each chapter may be found to present an individual topic and elaborate on a specific problem. But the chapters altogether have covered most of the basic aspects relevant to the title of the book. The book will be a vital reference for scientific understanding of lipid bilayers.
Book Synopsis Handbook of Lipid Membranes by : Cyrus R. Safinya
Download or read book Handbook of Lipid Membranes written by Cyrus R. Safinya and published by CRC Press. This book was released on 2021-09-15 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook provides a comprehensive overview of lipid membrane fundamentals and applications. It gives the fundamental physical and biochemical aspects of membrane-related processes in living cells, and then relates them to how scientists are building bioinspired, artifical membrane-based systems such as gene delivery vehicles and synthetic membrane interfaces. It highlights the driving mechanism behind lipid self-assembly, membrane shape evolution, and vesicle trafficing, as well as the role of lipid membrane composition in signalling and the structural aspects of membranes in cellular integrity. Key Features: Includes a broad overview on the role of lipids as structural components of membranes, energy storage molecules, and signaling molecules. Covers lipids in signaling and the role of lipids in everyday life, from diet and health to cosmetics and pharmaceuticals. Discusses applications in nanotechnology and biomedicine, including liposomes in drug discovery, lipids for in vivo therapeutics, lipid-based sensors, artificial biointerfaces, and synthetic polymers. Includes an exciting section that explores the practical use of Archae lipids, lipids and the origins of life, and future outlook for the field. This book is a great companion for professionals in physics, biochemistry, physical chemistry and material sciences.
