L'implication du marketing stratégique dans les stades précoces du développement en oncologie

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Publisher :
ISBN 13 :
Total Pages : 414 pages
Book Rating : 4.:/5 (492 download)

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Book Synopsis L'implication du marketing stratégique dans les stades précoces du développement en oncologie by : Mélice N'Damba

Download or read book L'implication du marketing stratégique dans les stades précoces du développement en oncologie written by Mélice N'Damba and published by . This book was released on 2004 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malgré les progrès accomplis dans la prise en charge du cancer du côlon, le pronostic de la maladie reste globalement mauvais. Cette pathologie représente donc encore un défi de taille pour l'industrire pharmaceutique car des besoins médicaux persistent et le marché, dont la taille pour l'industrie pharmaceutique car des besoins médicaux persistent et la marché dont la taille et la valeur ne cessent de croître, est en attente de thérapeutiques plus efficaces. Pour limiter les risques financiers liés à l'arrêt tardif du développement d'un nouveau traitement anticancéreux, les industriels vont devoir évaluer et analyser les probabilités de succès commercial du produit dès les prémices du développement en mettant en oeuvre un plan marketing stratégique. Typiquement, ces initiatives se traduisent par des études de marché et leur analyse pour cibler le marché, l'optimisations du profil produit cible, l'identification des leaders d'opinion, la segmentation des acteurs influents du marché et les programmes des leaders d'opinion clé"s, le développement du positionnement du produit, le planning d'une stratégie de communication et divers programmes de développement du marché avant lancement ciblés sur des audiences internes et externes. Le but de ces activités étant de savoir interrompre à temps un développement voué à l'échec et de donner aux nouveaux médicaments ayant un fort potentiel le meilleurdépart possible dès la communication.

Innovate Bristol

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Publisher :
ISBN 13 : 9781949677072
Total Pages : pages
Book Rating : 4.6/5 (77 download)

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Book Synopsis Innovate Bristol by : Sven Boermeester

Download or read book Innovate Bristol written by Sven Boermeester and published by . This book was released on 2019-12 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Innovate Bristol highlights and celebrates those companies and individuals that are actively working at building a better tomorrow for all. Innovation Ecosystems thrive through the involvement and support of companies and individuals from all industries, which is why the Innovate series not only focuses on the innovators but also those people whom the Innovation Ecosystem, would not be able to thrive without.

ENT Emergencies

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Publisher :
ISBN 13 : 9781416058298
Total Pages : 0 pages
Book Rating : 4.0/5 (582 download)

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Book Synopsis ENT Emergencies by : John L. Dornhoffer

Download or read book ENT Emergencies written by John L. Dornhoffer and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The head and neck, as an anatomical cross roads of multiple functions critical to human well being, including respiration, digestion, sensation, communication, and aesthetics, presents disorders that acutely threaten these vital systems. As with any emergency situation, information devoted to the priorities of management: airway, breathing, circulation, and disability are presented for otolaryngic emergencies that may manifest at each of these levels in the form of acute airway obstruction, epistaxis, and the gamut of traumatic, infectious, and inflammatory disorders that affect special sensation, neurologic function, and cosmesis. Discussed in this issue is the use of modalities such as endoscopy, optics, and radiologic imaging as a means to earlier diagnosis, detailed anatomic assessment, and minimally invasive surgery used in the emergency setting. This text strives to keep practitioners at the forefront in the management of ENT emergencies. Experts in otolaryngology describe those conditions that require urgent evaluation and treatment but are also relatively common. Where evidence-based medicine is lacking, comprehensive reviews of the controversies are presented along with logical treatment algorithms based on clinical expertise. This issue of Otolaryngologic Clinics should be highly relevant to the otolaryngologist as well as the general practitioner and emergency physician.

On-line Estimation and Adaptive Control of Bioreactors

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Publisher : Elsevier
ISBN 13 : 1483290980
Total Pages : 394 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis On-line Estimation and Adaptive Control of Bioreactors by : G. Bastin

Download or read book On-line Estimation and Adaptive Control of Bioreactors written by G. Bastin and published by Elsevier. This book was released on 2013-10-22 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with monitoring and control of biotechnological processes. Different methods are proposed which are based on the nonlinear structure of the process and do not require any a priori knowledge of the fermentation parameters. The theoretical stability and convergence properties of the proposed algorithms are analysed and their performances are illustrated by simulation results and, in many instances, by real life experiments. The concept of software sensors is introduced; these are algorithms based on the nonlinear model of the process and designed for on-line estimation of the biological variables and/or the fermentation parameters. In order to deal with process nonstationarities and parameter uncertainties, reference is made to adaptive estimation and control techniques.The book is the result of an intensive joint research effort by the authors during the last decade. It is intended as a graduate level text for students of bioengineering as well as a reference text for scientists and engineers involved in the design and optimization of bioprocesses.

Acupuncture in Practice

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Publisher :
ISBN 13 : 9780443050497
Total Pages : 482 pages
Book Rating : 4.0/5 (54 download)

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Book Synopsis Acupuncture in Practice by : Hugh MacPherson (Ph. D.)

Download or read book Acupuncture in Practice written by Hugh MacPherson (Ph. D.) and published by . This book was released on 1997 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by THE leading lights in the field of integrating acupuncture into a Western medical system, this book bridges the gap between the theoretical foundations of acupuncture and its application in a modern Western clinical context. Each case history focuses on the complexities and dilemmas of treatment that are tackled, providing valuable insights by experienced practitioners into the management of a course of acupuncture treatment.

Semigroups for Delay Equations

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Publisher : A K Peters, Ltd.
ISBN 13 : 9781568812434
Total Pages : 259 pages
Book Rating : 4.8/5 (124 download)

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Book Synopsis Semigroups for Delay Equations by : András Bátkai

Download or read book Semigroups for Delay Equations written by András Bátkai and published by A K Peters, Ltd.. This book was released on 2005 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: In most physical, chemical, biological and economic phenomena it is quite natural to assume that the system not only depends on the present state but also on past occurrences. These circumstances are mathematically described by partial differential equations with delay. This book presents, in a systematic fashion, how delay equations can be studied in Lp-history spaces.Appendices offering supplementary information and a comprehensive index make this book an ideal introduction and research tool for mathematicians, chemists, biologists and economists.

One-Parameter Semigroups for Linear Evolution Equations

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Publisher : Springer Science & Business Media
ISBN 13 : 0387226427
Total Pages : 609 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis One-Parameter Semigroups for Linear Evolution Equations by : Klaus-Jochen Engel

Download or read book One-Parameter Semigroups for Linear Evolution Equations written by Klaus-Jochen Engel and published by Springer Science & Business Media. This book was released on 2006-04-06 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the theory of strongly continuous one-parameter semigroups of linear operators. A special feature of the text is an unusually wide range of applications such as to ordinary and partial differential operators, to delay and Volterra equations, and to control theory. Also, the book places an emphasis on philosophical motivation and the historical background.

Geometric Control Theory

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Publisher : Cambridge University Press
ISBN 13 : 0521495024
Total Pages : 516 pages
Book Rating : 4.5/5 (214 download)

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Book Synopsis Geometric Control Theory by : Velimir Jurdjevic

Download or read book Geometric Control Theory written by Velimir Jurdjevic and published by Cambridge University Press. This book was released on 1997 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Geometric control theory is concerned with the evolution of systems subject to physical laws but having some degree of freedom through which motion is to be controlled. This book describes the mathematical theory inspired by the irreversible nature of time evolving events. The first part of the book deals with the issue of being able to steer the system from any point of departure to any desired destination. The second part deals with optimal control, the question of finding the best possible course. An overlap with mathematical physics is demonstrated by the Maximum principle, a fundamental principle of optimality arising from geometric control, which is applied to time-evolving systems governed by physics as well as to man-made systems governed by controls. Applications are drawn from geometry, mechanics, and control of dynamical systems. The geometric language in which the results are expressed allows clear visual interpretations and makes the book accessible to physicists and engineers as well as to mathematicians.

Positive 1D and 2D Systems

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Publisher : Springer Science & Business Media
ISBN 13 : 9781852335083
Total Pages : 450 pages
Book Rating : 4.3/5 (35 download)

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Book Synopsis Positive 1D and 2D Systems by : Tadeusz Kaczorek

Download or read book Positive 1D and 2D Systems written by Tadeusz Kaczorek and published by Springer Science & Business Media. This book was released on 2002 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is devoted to the positive multivariable 1D and 2D linear, time-invariant, finite-dimensional system. The book is based on the author's lectures for Ph.D. students, delivered at Warsaw University of Technology in the academic year 1999/2000. The book consists of two parts; the first part is devoted to the 1D positive linear systems and the second to the 2D positive linear systems described by the Rosser model and the Fornasini-Marchesini models. Definitions, basic properties and theorems concerning positive matrices and graphs are presented; the externally and internally positive linear continuous-time and discrete-time linear systems are considered; and the reachability, controlability and observability of positive linear systems are discussed. The realisation problem for positive 1D and 2D systems is also considered, and the 2D models of externally and internally positive and their properties and controllability and minimum energy control of positive 2D systems are investigated.

Fractional Linear Systems and Electrical Circuits

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Publisher : Springer
ISBN 13 : 3319113615
Total Pages : 260 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Fractional Linear Systems and Electrical Circuits by : Tadeusz Kaczorek

Download or read book Fractional Linear Systems and Electrical Circuits written by Tadeusz Kaczorek and published by Springer. This book was released on 2014-10-13 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph covers some selected problems of positive and fractional electrical circuits composed of resistors, coils, capacitors and voltage (current) sources. The book consists of 8 chapters, 4 appendices and a list of references. Chapter 1 is devoted to fractional standard and positive continuous-time and discrete-time linear systems without and with delays. In chapter 2 the standard and positive fractional electrical circuits are considered and the fractional electrical circuits in transient states are analyzed. Descriptor linear electrical circuits and their properties are investigated in chapter 3, while chapter 4 is devoted to the stability of fractional standard and positive linear electrical circuits. The reachability, observability and reconstructability of fractional positive electrical circuits and their decoupling zeros are analyzed in chapter 5. The fractional linear electrical circuits with feedbacks are considered in chapter 6. In chapter 7 solutions of minimum energy control for standard and fractional systems with and without bounded inputs is presented. In chapter 8 the fractional continuous-time 2D linear systems described by the Roesser type models are investigated.

Delay Equations

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Publisher : Springer Science & Business Media
ISBN 13 : 1461242061
Total Pages : 547 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Delay Equations by : Odo Diekmann

Download or read book Delay Equations written by Odo Diekmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim here is to provide an introduction to the mathematical theory of infinite dimensional dynamical systems by focusing on a relatively simple - yet rich - class of examples, delay differential equations. This textbook contains detailed proofs and many exercises, intended both for self-study and for courses at graduate level, as well as a reference for basic results. As the subtitle indicates, this book is about concepts, ideas, results and methods from linear functional analysis, complex function theory, the qualitative theory of dynamical systems and nonlinear analysis. The book provides the reader with a working knowledge of applied functional analysis and dynamical systems.

Infinite Dimensional Linear Systems Theory

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Publisher : Springer
ISBN 13 :
Total Pages : 320 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Infinite Dimensional Linear Systems Theory by : Ruth F. Curtain

Download or read book Infinite Dimensional Linear Systems Theory written by Ruth F. Curtain and published by Springer. This book was released on 1978 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Selected Problems of Fractional Systems Theory

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Publisher : Springer Science & Business Media
ISBN 13 : 3642205011
Total Pages : 353 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Selected Problems of Fractional Systems Theory by : Tadeusz Kaczorek

Download or read book Selected Problems of Fractional Systems Theory written by Tadeusz Kaczorek and published by Springer Science & Business Media. This book was released on 2011-05-10 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph covers some selected problems of positive fractional 1D and 2D linear systems. It is an extended and modified English version of its preceding Polish edition published by Technical University of Bialystok in 2009. This book is based on the lectures delivered by the author to the Ph.D. students of the Faculty of Electrical Engineering of Bialystok University of Technology and of Warsaw University of Technology and on invited lectures in several foreign universities in the last three years.