Les Troubles Du Spectre Autistique Au Liban

Download Les Troubles Du Spectre Autistique Au Liban full books in PDF, epub, and Kindle. Read online Les Troubles Du Spectre Autistique Au Liban ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Les troubles du spectre autistique au Liban

Author : Perla Gerges
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (141 download)

DOWNLOAD NOW!

Book Synopsis Les troubles du spectre autistique au Liban by : Perla Gerges

Download or read book Les troubles du spectre autistique au Liban written by Perla Gerges and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Les troubles du spectre autistique (TSA) sont des troubles neurodéveloppementaux complexes et multifactoriels impliquant des facteurs génétiques ainsi que des facteurs environnementaux. Il a été montré que des événements prénatals, périnatals et postnatals peuvent soit augmenter soit diminuer le risque des TSA. Les facteurs environnementaux sont susceptibles de moduler le risque des TSA lorsqu'ils sont associés avec des facteurs génétiques. En fait, des anomalies chromosomiques, des variations du nombre de copies (CNV) et des variants mononucléotidiques (SNV) ont été associés aux TSA. A ce jour, les facteurs environnementaux et génétiques ne sont pas encore complètement élucidés et la plupart des études sur les TSA sont menées sur les populations Américaines et Ouest-Européennes. Par conséquent, les objectifs de ma thèse s'articulent autour de l'identification des facteurs de risque et de protection qui peuvent aider à la compréhension de la physiopathologie des TSA et enfin à aboutir à l'atténuation des risques, ainsi que sur l'identification des variations mononucléotidiques (SNV) et des petites insertions/délétions (indels) par le séquençage de l'exome entier (WES) chez cinq sujets qui n'avaient pas révélé de CNV liées aux TSA dans notre étude précédente. Pour le premier objectif, nos résultats ont montré que le stress pendant la grossesse, la présence de patients atteints de TSA et de patients atteints du trouble d'hyperactivité avec déficit de l'attention (TDAH) dans la famille étaient significativement associés aux TSA. D'autre part, un apport en multivitamines en particulier les vitamines B et en oméga 3, un régime riche en céréales et une supplémentation en fer pendant la grossesse ont été identifiés comme des facteurs de protection contre les TSA. Pour le second objectif, notre étude a permis d'identifier un variant de novo dans le gène MIS18BP1 et deux autres variants hérités dans les gènes SLITRK4 et NHSL2. En outre, nos résultats ont confirmé la présence d'autres variations génétiques précédemment décrites et partagées entre les patients Libanais et d'autres populations atteintes de TSA. L'expression du gène MIS18BP1 a été analysée par PCR quantitative en temps réel (RT qPCR) dans le cortex de souris à différents stades de développement et les résultats ont montré qu'il est fortement exprimé au stade embryonnaire Ces études ont permis d'établir de nouvelles hypothèses, de confirmer les données précédentes et de contribuer à la compréhension des TSA. Cependant, des investigations supplémentaires doivent encore être réalisées pour aboutir à une validation des facteurs de risque et des gènes candidats, afin de donner une compréhension cohérente de l'interaction entre les différents facteurs associés aux TSA.

Etude épidémiologique, génétique et métabolomique des Troubles du Spectre Autistique au Liban

Author : Tania Bitar
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (111 download)

DOWNLOAD NOW!

Book Synopsis Etude épidémiologique, génétique et métabolomique des Troubles du Spectre Autistique au Liban by : Tania Bitar

Download or read book Etude épidémiologique, génétique et métabolomique des Troubles du Spectre Autistique au Liban written by Tania Bitar and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: L'étiologie des troubles du spectre autistique (TSA) est multifactorielle mettant en jeu une forte composante génétique ainsi que des facteurs environnementaux. A ce jour, il n'existe aucun biomarqueur facilitant un diagnostic précoce des TSA, ce qui permettrait une meilleure prise en charge des patients. De plus, les mécanismes physiopathologiques sont encore mal connus. La majorité des études sur les TSA ont été réalisées sur des populations occidentales. Ainsi, nous avons voulu étudier un groupe de patients libanais atteints de TSA. Nos objectifs s'articulent autour de trois volets : 1) L'identification de facteurs de risques environnementaux dans le but de mieux comprendre la pathologie. Les résultats de cette étude ont montré que plusieurs facteurs tels que la consanguinité, le stress au cours de la grossesse et la prématurité semblent être des facteurs de risques. 2) L'identification des variations structurales dans le génome des enfants atteints de TSA afin d'évaluer la contribution de CNV par l'approche de CGH array à haute résolution. Cette étude nous a permis d'identifier de nouveaux gènes dans les TSA ainsi de confirmer la présence des régions et des gènes déjà cités dans des études précédentes sur les TSA. 3) L'identification des métabolites urinaires et des voies métaboliques associés afin de proposer des biomarqueurs aidant à un diagnostic précoce et à une meilleure compréhension de la physiopathologie de la maladie. De nouveaux métabolites ont été identifiés, comme nous avons confirmé des variations anomalies déjà citées dans la littérature concernant certains métabolites qui pourraient représenter des marqueurs robustes de la maladie.

Etude épidémiologique de l'autisme et des troubles apparentés au Liban

Author : Mireille Yaghalian
Publisher :
ISBN 13 :
Total Pages : 30 pages
Book Rating : 4.:/5 (113 download)

DOWNLOAD NOW!

Book Synopsis Etude épidémiologique de l'autisme et des troubles apparentés au Liban by : Mireille Yaghalian

Download or read book Etude épidémiologique de l'autisme et des troubles apparentés au Liban written by Mireille Yaghalian and published by . This book was released on 2011 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Assessing Multilingual Children

Author : Sharon Armon-Lotem
Publisher : Multilingual Matters
ISBN 13 : 1783093129
Total Pages : 376 pages
Book Rating : 4.7/5 (83 download)

DOWNLOAD NOW!

Book Synopsis Assessing Multilingual Children by : Sharon Armon-Lotem

Download or read book Assessing Multilingual Children written by Sharon Armon-Lotem and published by Multilingual Matters. This book was released on 2015 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Second language learners often produce language forms resembling those of children with Specific Language Impairment (SLI). At present, professionals working in language assessment and education have only limited diagnostic instruments to distinguish language impaired migrant children from those who will eventually catch up with their monolingual peers. This book presents a comprehensive set of tools for assessing the linguistic abilities of bilingual children. It aims to disentangle effects of bilingualism from those of SLI, making use of both models of bilingualism and models of language impairment. The book's methods-oriented focus will make it an essential handbook for practitioners who look for measures which could be adapted to a variety of languages in diverse communities, as well as academic researchers.

Developing Narrative Comprehension

Author : Ute Bohnacker
Publisher : John Benjamins Publishing Company
ISBN 13 : 9027260346
Total Pages : 351 pages
Book Rating : 4.0/5 (272 download)

DOWNLOAD NOW!

Book Synopsis Developing Narrative Comprehension by : Ute Bohnacker

Download or read book Developing Narrative Comprehension written by Ute Bohnacker and published by John Benjamins Publishing Company. This book was released on 2020-12-15 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehension of texts and understanding of questions is a cornerstone of successful human communication. Whilst reading comprehension has been thoroughly investigated in the last decade, there is surprisingly little research on children’s comprehension of picture stories, particularly for bilinguals. This can be partially explained by the lack of cross-culturally robust, cross-linguistic instruments targeting early narration. This book presents an inference-based model of narrative comprehension and a tool that grew out of a large-scale European project on multilingualism. Covering a range of language settings, the book uses the Multilingual Assessment Instrument for Narratives to answer the question which narrative comprehension skills (bilingual) children can be expected to master at a certain age, and explores how such comprehension is affected (or not affected) by linguistic and extra-linguistic factors. Linking theory to method, the book will appeal to researchers in linguistics and psychology and graduate students interested in narrative, multilingualism, and language acquisition.

Pediatric Bipolar Disorder

Author : Robert L. Findling
Publisher : CRC Press
ISBN 13 : 9781841840543
Total Pages : 180 pages
Book Rating : 4.8/5 (45 download)

DOWNLOAD NOW!

Book Synopsis Pediatric Bipolar Disorder by : Robert L. Findling

Download or read book Pediatric Bipolar Disorder written by Robert L. Findling and published by CRC Press. This book was released on 2002-10-10 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bipolar disorders were once considered rare in children and adolescents. A growing body of scientific evidence now suggests that they may be more prevalent in this group than previously believed. At the same time, the practitioner faces significant clinical challenges in both the assessment processes and also the implementation of a treatment plan. A paucity of treatment manuals and pharmacological algorithms providing practical guidance makes the task of the clinician even more difficult, despite the fact that more is known about the assessment, neurobiology and treatment of children and adolescents with bipolar disorder than ever before. Written by three distinguished experts, this book conveys to clinicians all the information currently available in this area. They review both the neuroscience and also the integration of rational, practical, pharmacological and psychosocial interventions. Based on what is known, a sound approach to the assessment of these youngsters can be developed. Similarly, available evidence allows practitioners to ground their treatment protocols solidly on scientific knowledge. Concise and authoritative, Pediatric Bipolar Disorders will give the reader a practical approach to both the art and science of providing the best possible clinical care to children and adolescents with the disorder. This book is written primarily for clinical psychiatrists, but will also be of interest to non-specialist doctors and other members of the health care team.

Short-term and Working Memory

Author : Susan E. Gathercole
Publisher : Psychology Press
ISBN 13 : 9781841699189
Total Pages : 268 pages
Book Rating : 4.6/5 (991 download)

DOWNLOAD NOW!

Book Synopsis Short-term and Working Memory by : Susan E. Gathercole

Download or read book Short-term and Working Memory written by Susan E. Gathercole and published by Psychology Press. This book was released on 2001 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special issue ponders a detailed and contemporary analysis of the theoretical underpinnings of short-term and working memory. Articles focus on short-term memory for phonological, semantic, and spatial material, on executive function and on short-term forgetting. The empirical perspectives include the neuroimaging of short-term memory, short-term memory development and the neuropsychology and neurobiology of memory, in addition to laboratory-based experimental studies. Together, these articles identify significant current models and approaches to short-term and working memory, providing a broad set of perspectives which illustrate the wide impact of working memory on the understanding of human cognition.

Spílexm

Author : Nicola I. Campbell
Publisher : Portage & Main Press
ISBN 13 : 1553799704
Total Pages : 236 pages
Book Rating : 4.5/5 (537 download)

DOWNLOAD NOW!

Book Synopsis Spílexm by : Nicola I. Campbell

Download or read book Spílexm written by Nicola I. Campbell and published by Portage & Main Press. This book was released on 2021-12-23 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: If the hurt and grief we carry is a woven blanket, it is time to weave ourselves anew. In the Nłeʔkepmxcín language, spíləx̣m are remembered stories, often shared over tea in the quiet hours between Elders. Rooted within the British Columbia landscape, and with an almost tactile representation of being on the land and water, Spíləx̣m explores resilience, reconnection, and narrative memory through stories. Captivating and deeply moving, this story basket of memories tells one Indigenous woman’s journey of overcoming adversity and colonial trauma to find strength through creative works and traditional perspectives of healing, transformation, and resurgence.

Bilingualism Across the Lifespan

Author : Elena Nicoladis
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110341247
Total Pages : 361 pages
Book Rating : 4.1/5 (13 download)

DOWNLOAD NOW!

Book Synopsis Bilingualism Across the Lifespan by : Elena Nicoladis

Download or read book Bilingualism Across the Lifespan written by Elena Nicoladis and published by Walter de Gruyter GmbH & Co KG. This book was released on 2016-06-20 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book pioneers the study of bilingualism across the lifespan and in all its diverse forms. In framing the newest research within a lifespan perspective, the editors highlight the importance of considering an individual's age in researching how bilingualism affects language acquisition and cognitive development. A key theme is the variability among bilinguals, which may be due to a host of individual and sociocultural factors, including the degree to which bilingualism is valued within a particular context.Thus, this book is a call for language researchers, psychologists, and educators to pursue a better understanding of bilingualism in our increasingly global society.

First Language Attrition

Author : Monika S. Schmid
Publisher : John Benjamins Publishing
ISBN 13 : 902727195X
Total Pages : 167 pages
Book Rating : 4.0/5 (272 download)

DOWNLOAD NOW!

Book Synopsis First Language Attrition by : Monika S. Schmid

Download or read book First Language Attrition written by Monika S. Schmid and published by John Benjamins Publishing. This book was released on 2013-05-22 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume consists of a collection of papers that focus on structural/grammatical aspects of the process of first language attrition. It presents an overview of current research, methodological issues and important questions regarding first language attrition. In particular, it addresses the two most prominent issues in current L1 attrition research: Can attrition effects impact on features of core syntax, or are they limited to interface phenomena?, and; What is the role of age at onset (pre-/post-puberty) in this regard? By investigating attrition in a variety of settings, from a case study of a Spanish-speaking adoptee in the US to an empirical investigation of more than 50 long-term attriters of Turkish in the Netherlands, the investigations presented take a new perspective on these issues. Originally published in Language, Interaction and Acquisition - Langage, Interaction et Acquisition 2:2 (2011).

BUCLD 44: Proceedings of the 44th Annual Boston University Conference on Language Development

Author : Megan M. Brown
Publisher :
ISBN 13 : 9781574730579
Total Pages : 758 pages
Book Rating : 4.7/5 (35 download)

DOWNLOAD NOW!

Book Synopsis BUCLD 44: Proceedings of the 44th Annual Boston University Conference on Language Development by : Megan M. Brown

Download or read book BUCLD 44: Proceedings of the 44th Annual Boston University Conference on Language Development written by Megan M. Brown and published by . This book was released on 2020 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume set contains 60 talks and posters from the 44th annual Boston University Conference on Language Development, held November 7-10, 2019.

Freud Along the Ganges

Author : Salman Akhtar
Publisher : Other Press, LLC
ISBN 13 : 1635421160
Total Pages : 473 pages
Book Rating : 4.6/5 (354 download)

DOWNLOAD NOW!

Book Synopsis Freud Along the Ganges by : Salman Akhtar

Download or read book Freud Along the Ganges written by Salman Akhtar and published by Other Press, LLC. This book was released on 2020-09-15 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the 2006 Gradiva Award A collection of new and previously-published essays that sheds light on the intersections between psychoanalysis and Indic Studies. While Indian academics and clinicians have been familiar with psychoanalysis for many decades, they have kept this Western model of the mind separate from the spiritual and philosophical traditions of their own country. Freud Along the Ganges bridges this important lacuna in psychoanalytic and Indic studies by creating a new theoretical field where human motives are approached not only psychoanalytically but also from the perspective of the teachings of Buddha, Tagore, Ghandi, and Salman Rushdie. The authors of this collection show how the insights of these Indian masters give a new force to the Freudian discovery by providing a basis to better understand the social and psychological Indian makeup. The book begins by questioning the applicability of the psychoanalytic method to non-Western cultures. It then traces the history of the psychoanalytic movement in India from its onset while it emphasizes the intricate overlap between Indian existential and mystical traditions and psychoanalysis. Freud Along the Ganges offers a unique study of the ways that Indian thought and psychoanalysis illuminate and enrich each other.

Michel Houellebecq and the Literature of Despair

Author : Carole Sweeney
Publisher : A&C Black
ISBN 13 : 1623569184
Total Pages : 289 pages
Book Rating : 4.6/5 (235 download)

DOWNLOAD NOW!

Book Synopsis Michel Houellebecq and the Literature of Despair by : Carole Sweeney

Download or read book Michel Houellebecq and the Literature of Despair written by Carole Sweeney and published by A&C Black. This book was released on 2013-11-21 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Widely acknowledged as an important, if highly controversial, figure in contemporary literature, French novelist and poet Michel Houellebecq has elicited diverse critical responses. In this book Carole Sweeney examines his novels as a response to the advance of neoliberalism into all areas of affective human life. This historicizing study argues that le monde houellebecquien is an 'atomised society' of banal quotidian alienation populated by quietly resentful men who are the botched subjects of late-capitalism. Addressing Houellebecq's handling of the 'failure' of the radical thought of '68, Sweeney looks at the ways in which his fiction treats feminism, the decline of religion and the family, as well as the obsolescence of French 'theory' and the Sartrean notion of 'engaged' literature. Reading the world with the disappointed idealism of a contemporary moralist, Houellebecq's novels, Sweeney argues, fluctuate between despair for the world as it is and a limp utopian hope for a post-humanity.

An Englishman in Paris; Notes and Recollections

Author : Albert Dresden VanDam
Publisher : Nabu Press
ISBN 13 : 9781177437219
Total Pages : 354 pages
Book Rating : 4.4/5 (372 download)

DOWNLOAD NOW!

Book Synopsis An Englishman in Paris; Notes and Recollections by : Albert Dresden VanDam

Download or read book An Englishman in Paris; Notes and Recollections written by Albert Dresden VanDam and published by Nabu Press. This book was released on 2010-08 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a reproduction of a book published before 1923. This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book.

The Frontal Lobes

Author :
Publisher : Academic Press
ISBN 13 : 0128043261
Total Pages : 510 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis The Frontal Lobes by :

Download or read book The Frontal Lobes written by and published by Academic Press. This book was released on 2019-10-05 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Frontal Lobes, Volume 163, updates readers on the latest thinking on the structure and function of the human frontal lobe. Sections address methodology, anatomy, physiology and pharmacology, function, development, aging and disorders, and rehabilitation. Patients with focal lesions in the frontal lobes have long been studied to reveal the organization and function of the frontal lobes. Over the last two decades, studies of patients with neurodegenerative diseases and developmental disorders have increased, with new findings discussed in this volume. In addition, the book includes discussions on genetics and molecular biology, optogenetics, high-resolution structural and functional neuroimaging and electrophysiology, and more. Lastly, new knowledge on the biology, structure and function of the frontal lobes, new treatment targets for pharmacology, non-invasive brain stimulation, and cognitive/social remediation are presented. The last section covers new efforts that will hopefully lead to better outcomes in patients with frontal lobe disorders. Provides an overview of the structure, function, disorder and rehabilitation of the frontal lobes Addresses a wide variety of methodologies – from genetics and molecular biology, to optogenetics and hi-res fMRI, and more Contains content of interest to advanced students, junior researchers and clinicians getting involved in research Features the input of leaders in neuroanatomical research from around the globe – the broadest, most expert coverage available

Toward the United Front

Author : Communistische Internationale
Publisher : BRILL
ISBN 13 : 9004207783
Total Pages : 1323 pages
Book Rating : 4.0/5 (42 download)

DOWNLOAD NOW!

Book Synopsis Toward the United Front by : Communistische Internationale

Download or read book Toward the United Front written by Communistische Internationale and published by BRILL. This book was released on 2011-10-14 with total page 1323 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers, for the first time in English, the proceedings and decisions of the last congress of the Communist International held in Lenin’s lifetime. With an analytic introduction, detailed footnotes, 500 biographic notes, glossary, chronology, and index.

Language Acquisition and Development

Author : Cornelia Hamann
Publisher : Cambridge Scholars Publishing
ISBN 13 : 1443884138
Total Pages : 615 pages
Book Rating : 4.4/5 (438 download)

DOWNLOAD NOW!

Book Synopsis Language Acquisition and Development by : Cornelia Hamann

Download or read book Language Acquisition and Development written by Cornelia Hamann and published by Cambridge Scholars Publishing. This book was released on 2015-10-05 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited collection contains 34 papers originally presented at the Generative Approaches to Language Acquisition (GALA) conference in 2013, held in Oldenburg, Germany. It represents theoretically guided, high quality work, and provides impressive insights into state-of-the-art research in the fields of first and second language acquisition and developmental impairments. The studies brought together here cover a wide variety of different (mainly European) languages, focusing on the areas of phonology, morpho-syntax, semantics, pragmatics, and their interfaces. Since their first publication, the proceedings of GALA have become an invaluable reference for cutting-edge research in First and Second Language Acquisition and its impairments – and this volume continues that tradition.