Leptin and Glucocorticoids Exert Opposing Actions on Neuropeptide Y and Corticotropin-releasing Hormone Secretion Within the Hypothalamus

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ISBN 13 :
Total Pages : 332 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis Leptin and Glucocorticoids Exert Opposing Actions on Neuropeptide Y and Corticotropin-releasing Hormone Secretion Within the Hypothalamus by : Miyoung Jang

Download or read book Leptin and Glucocorticoids Exert Opposing Actions on Neuropeptide Y and Corticotropin-releasing Hormone Secretion Within the Hypothalamus written by Miyoung Jang and published by . This book was released on 1999 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Leptin and Reproduction

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Publisher : Springer Science & Business Media
ISBN 13 : 1461501571
Total Pages : 352 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Leptin and Reproduction by : Michael C. Henson

Download or read book Leptin and Reproduction written by Michael C. Henson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The isolation of leptin in 1994 and its characterization as a factor influencing appetite, energy balance, and adiposity, immediately thrust the polypeptide into the rapidly growing body of literature centered on the physiology of obesity. The growing clinical awareness of obesity as a major health risk in developed societies dovetailed perfectly with any of a number of roles that leptin might play in this abenant physiological condition. Almost unnoticed amidst the excitement generated by early leptin publications was the suggestion that the "fat hormone" might also regulate a wide range of systems and events important to reproduction, including pubertal development, gonadal endocrinology, fettility, and pregnancy. Recognizing this potential, a relatively small cadre of researchers began to examine leptin specifically as a reproductive hormone, thus creating a new and fertile field of investigation. Interest in this area has since gained momentum and an increased number of participants have now made significant contributions to our understanding of many leptin-related mechanisms that are relevant to reproductive biology. Leptin and Reproduction is the first major volume to specifically address leptin as a reproductive hormone and closely examines the advances made in the short time since this field of interest developed. Preeminent researchers ti'om many of the subdisciplines working within this area present a welcomed compendium of the wealth of related literature and voice novel interpretations of cun'ent advances.

ACTH Action in the Adrenal Cortex: From Molecular Biology to Pathophysiology

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Publisher : Frontiers Media SA
ISBN 13 : 2889452328
Total Pages : 421 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis ACTH Action in the Adrenal Cortex: From Molecular Biology to Pathophysiology by : Nicole Gallo-Payet

Download or read book ACTH Action in the Adrenal Cortex: From Molecular Biology to Pathophysiology written by Nicole Gallo-Payet and published by Frontiers Media SA. This book was released on 2017-07-27 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: By stimulating adrenal gland and corticosteroid synthesis, the adrenocorticotropic hormone (ACTH) plays a central role in response to stress. In this Research Topic, a particular attention has been given to the recent developments on adrenocortical zonation; the growth-promoting activities of ACTH; the various steps involved in acute and chronic regulation of steroid secretion by ACTH, including the effect of ACTH on circadian rhythms of glucocorticoid secretion. The Research Topic also reviews progress and challenges surrounding the properties of ACTH binding to the MC2 receptor (MC2R), including the importance of melanocortin-2 receptor accessory protein (MRAP) in MC2R expression and function, the various intracellular signaling cascades, which involve not only protein kinase A, the key mediator of ACTH action, but also phosphatases, phosphodiesterases, ion channels and the cytoskeleton. The importance of the proteins involved in the cell detoxification is also considered, in particular the effect that ACTH has on protection against reactive oxygen species generated during steroidogenesis. The impact of the cellular microenvironment, including local production of ACTH is discussed, both as an important factor in the maintenance of homeostasis, but also in pathological situations, such as severe inflammation. Finally, the Research Topic reviews the role that the pituitary-adrenal axis may have in the development of metabolic disorders. In addition to mutations or alterations of expression of genes encoding components of the steroidogenesis and signaling pathways, chronic stress and sleep disturbance are both associated with hyperactivity of the adrenal gland. A resulting effect is increased glucocorticoid secretion inducing food intake and weight gain, which, in turn, leads to insulin and leptin resistance. These aspects are described in detail in this Research Topic by key investigators in the field. Many of the aspects addressed in this Research Topic still represent a stimulus for future studies, their outcome aimed at providing evidence of the central position occupied by the adrenal cortex in many metabolic functions when its homeostasis is disrupted. An in-depth investigation of the mechanisms underlying these pathways will be invaluable in developing new therapeutic tools and strategies.

Sleep and Mental Illness

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Publisher : Cambridge University Press
ISBN 13 : 1139483706
Total Pages : 451 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Sleep and Mental Illness by : S. R. Pandi-Perumal

Download or read book Sleep and Mental Illness written by S. R. Pandi-Perumal and published by Cambridge University Press. This book was released on 2010-04-01 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The diagnosis of mental illness is frequently accompanied by sleep problems; conversely, people experiencing sleep problems may subsequently develop mental illness. Sleep and Mental Illness looks at this close correlation and considers the implications of research findings that have emerged in the last few years. Additionally, it surveys the essential concepts and practical tools required to deal with sleep and co-morbid psychiatric problems. The volume is divided into three main sections: basic science, neuroendocrinology, and clinical science. Included are over 30 chapters on topics such as neuropharmacology, insomnia, depression, dementia, autism, and schizophrenia. Relevant questionnaires for the assessment of sleep disorders, including quality-of-life measurement tools, are provided. There is also a summary table of drugs for treating sleep disorders. This interdisciplinary text will be of interest to clinicians working in psychiatry, behavioral sleep medicine, neurology, pulmonary and critical care medicine.

Glucocorticoid Signaling

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Publisher : Springer
ISBN 13 : 1493928953
Total Pages : 387 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Glucocorticoid Signaling by : Jen-Chywan Wang

Download or read book Glucocorticoid Signaling written by Jen-Chywan Wang and published by Springer. This book was released on 2015-07-27 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely volume provides a comprehensive overview of glucocorticoids and their role in regulating many aspects of physiology and their use in the treatment of disease. The book is broken into four sections that begin by giving a general introduction to glucocorticoids and a brief history of the field. The second section will discuss the effects of glucocorticoids on metabolism, while the third section will cover the effects of glucocorticoids on key tissues. The final section will discuss general topics, such as animal models in glucocorticoid research and clinical implications of glucocorticoid research. Featuring chapters from leaders in the field, this volume will be of interest to both researchers and clinicians.

The Psychobiology of Anorexia Nervosa

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Publisher : Springer Science & Business Media
ISBN 13 : 3642695949
Total Pages : 190 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis The Psychobiology of Anorexia Nervosa by : K.M. Pirke

Download or read book The Psychobiology of Anorexia Nervosa written by K.M. Pirke and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Endocrine Hypertension

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Publisher : Elsevier
ISBN 13 : 0323957323
Total Pages : 412 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Endocrine Hypertension by : Joseph M. Pappachan

Download or read book Endocrine Hypertension written by Joseph M. Pappachan and published by Elsevier. This book was released on 2022-10-27 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine Hypertension: From Basic Science to Clinical Practice bridges the gap between scientists and practicing clinicians by providing a comprehensive overview on all forms of endocrine hypertension, covering epidemiological aspects, pathophysiology, clinical presentation, laboratory evaluation and practical management aspects of endocrine hypertension. This book is a great resource for endocrinologists, physicians, general practitioners and researchers who are eager to understand the complex facets of endocrine hypertension. Endocrine hypertension is a term used to describe a group of endocrine pathologies that cause an elevation of blood pressure, estimated to account for up to 10% of all hypertension cases. Although common, this clinical condition is often overlooked. Patients with this condition are at risk of late diagnosis, delayed treatment and detrimental health consequences. Provides a comprehensive overview on all forms of endocrine hypertension Discusses molecular physiology and pathophysiology of various endocrine hypertension related conditions and offers guidance to diagnosis and management of endocrine hypertension Includes instructional overview figures, diagrams, flowcharts, scan images and tables to enhance understanding

Handbook of Neurochemistry and Molecular Neurobiology

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Publisher : Springer Science & Business Media
ISBN 13 : 0387303480
Total Pages : 691 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Handbook of Neurochemistry and Molecular Neurobiology by : Ramon Lim

Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Ramon Lim and published by Springer Science & Business Media. This book was released on 2006-09-18 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Handbook is intended to be a service to the neuroscience community, to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors and most important, it represents support for research in this discipline. Based on the rapid advances in the years since the second edition."--Publisher's website.

Principles of Endocrinology and Hormone Action

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Publisher : Springer
ISBN 13 : 9783319446745
Total Pages : 0 pages
Book Rating : 4.4/5 (467 download)

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Book Synopsis Principles of Endocrinology and Hormone Action by : Antonino Belfiore

Download or read book Principles of Endocrinology and Hormone Action written by Antonino Belfiore and published by Springer. This book was released on 2018-02-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.

Dissertation Abstracts International

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ISBN 13 :
Total Pages : 782 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Dissertation Abstracts International by :

Download or read book Dissertation Abstracts International written by and published by . This book was released on 2000 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Neuroendocrinology

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Publisher : Cambridge University Press
ISBN 13 : 1316645193
Total Pages : 207 pages
Book Rating : 4.3/5 (166 download)

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Book Synopsis Clinical Neuroendocrinology by : Michael Wilkinson

Download or read book Clinical Neuroendocrinology written by Michael Wilkinson and published by Cambridge University Press. This book was released on 2019-01-03 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise and innovative account of clinical neuroendocrine disorders and the key principles underlying their diagnosis and management.

Neuroendocrinology in Physiology and Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 1592597076
Total Pages : 560 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Neuroendocrinology in Physiology and Medicine by : P. Michael Conn

Download or read book Neuroendocrinology in Physiology and Medicine written by P. Michael Conn and published by Springer Science & Business Media. This book was released on 1999-10-06 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: A panel of leading experts integrate the latest findings from basic and clinical science to create a comprehensive treatment of the processes by which the brain acts as an endocrine organ, not only to control hormonal functions, but also to maintain homeostasis and regulate behavior. The authors-recognized both as leaders in their fields and as skilled teachers-provide systematic coverage of the analytical, anatomical, functional, clinical, and pathological aspects of neuroendocrinology. Topics range from the interactions between the nervous and endocrine systems to the regulation of reproduction, development, metabolism, fluid balance, and biological rhythms. Neuroendocrinology in Physiology and Medicine offers an unprecedented marriage of clinical and basic knowledge that has been missing from classical neuroscience, endocrinology, and physiology texts. It will teach today's medical students and serve researchers as a valuable reference to this rapidly growing field.

The Hypothalamus

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Publisher :
ISBN 13 :
Total Pages : 514 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Hypothalamus by : Seymour Reichlin

Download or read book The Hypothalamus written by Seymour Reichlin and published by . This book was released on 1978 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Polycystic Ovary Syndrome

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Publisher : Springer Science & Business Media
ISBN 13 : 1597451088
Total Pages : 361 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Polycystic Ovary Syndrome by : Andrea Dunaif

Download or read book Polycystic Ovary Syndrome written by Andrea Dunaif and published by Springer Science & Business Media. This book was released on 2008-01-12 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1796 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1796 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Textbook Of Medical Physiology

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Publisher : Elsevier India
ISBN 13 : 9788181478504
Total Pages : 1332 pages
Book Rating : 4.4/5 (785 download)

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Book Synopsis Textbook Of Medical Physiology by : Khurana

Download or read book Textbook Of Medical Physiology written by Khurana and published by Elsevier India. This book was released on 2005 with total page 1332 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents an exhaustive and thorough exposition of the fundamentals of medical physiology. The exposition is divided systematically into three sections covering General Physiology, Systemic Physiology and Specialized Integrative Physiology. Each section begins with a brief Introduction highlighting the topics covered. The subject is then explained in a graded manner with a large number of tables, flowcharts and diagrams to aid understanding. The level of exposition in the book is sufficiently detailed for it to serve as a useful text for undergraduate courses as well as for PG entrance examinations About the Author : - Indu Khurana, Associate Professor, Department of Physiology, Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India.

The Hypothalamus-Pituitary-Adrenal Axis

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Publisher : Elsevier
ISBN 13 : 0080559360
Total Pages : 413 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Hypothalamus-Pituitary-Adrenal Axis by :

Download or read book The Hypothalamus-Pituitary-Adrenal Axis written by and published by Elsevier. This book was released on 2008-09-12 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later