Lens Epithelium and Posterior Capsular Opacification

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Author :
Publisher : Springer
ISBN 13 : 4431543007
Total Pages : 428 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Lens Epithelium and Posterior Capsular Opacification by : Shizuya Saika

Download or read book Lens Epithelium and Posterior Capsular Opacification written by Shizuya Saika and published by Springer. This book was released on 2014-08-12 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first to summarize the current knowledge of the cell biology of lens epithelial cells in relation to and in the development of posterior capsular opacification (PCO). PCO remains the most common long-term complication of modern cataract surgery, occurring months or years after cataract surgery, unlike most other complications that tend to arise during or soon after the procedure. Opacification of the posterior capsule appears to be linked to lens epithelial cells that are left behind in the eye during cataract removal. These cells proliferate, migrate across the posterior lens capsule, and undergo changes that result in fibrous or pearl-type opacities in the capsule. The first section of the text explains the molecular mechanism and biology of lens epithelial cells that lead to the incidence of PCO. In the second part, in addition to a description of the mechanism and pathological condition of PCO, surgical methods and devices for preventing PCO are discussed in detail. Lens Epithelium and Capsular Opacification will benefit not only young clinical residents and junior researchers, but also established faculty in the clinical or basic academic field.

Webvision

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (53 download)

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Book Synopsis Webvision by : Helga Kolb

Download or read book Webvision written by Helga Kolb and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Scrub's Bible

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Publisher : Springer Nature
ISBN 13 : 3030443450
Total Pages : 215 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis The Scrub's Bible by : Richard S. Koplin

Download or read book The Scrub's Bible written by Richard S. Koplin and published by Springer Nature. This book was released on 2020-06-27 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​The second edition of The Scrub's Bible is a timely, comprehensive resource, which will include extensive chapter and content updates, along with 50 new images and drawings. Updated sections will delve into subjects of endothelial transplantation, as well as cataract surgery and new medical and technological developments: femtosecond lasers, innovations in premium lens implant technologies, optiwave refractive analysis, and combined glaucoma and cataract surgery. Additional extensive chapter updates in the surgical tray, self-assessment, and corneal transplantation will be described in great detail as well. ​Directed at the growing number of untutored personnel aspiring to enter the disciplines of ophthalmic technicianry and surgical assisting, ​The Scrub's Bible, 2nd edition remains a key entry level guide to understanding the human eye, its basic anatomy, and physiology. Absorbing this information serves as the foundation for the authors, who are all skilled and respected eye surgeons, educators, and surgery center owners, to draw the reader through the fundamentals of the two most common areas of ophthalmic surgery: cataract and corneal/refractive surgery. The Scrub's Bible​ 2nd edition will build upon the first edition--remaining an easy-to-read tool that is broken down into discreet and understandable elements, meant to avoid the intimidating rhetoric of a standard reference.

Small Incision Cataract Surgery (Manual Phaco)

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Author :
Publisher : JP Medical Ltd
ISBN 13 : 8184489803
Total Pages : 290 pages
Book Rating : 4.1/5 (844 download)

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Book Synopsis Small Incision Cataract Surgery (Manual Phaco) by : Kamaljeet Singh

Download or read book Small Incision Cataract Surgery (Manual Phaco) written by Kamaljeet Singh and published by JP Medical Ltd. This book was released on 2010-03 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phacoemulsification with a small incision is the most common method of removing cataracts used today. Despite its popularity it is a technique that requires great skill and much practice. This book presents a broad overview of the technique, its complications and pitfalls and pays particular attention to management of patient pain and other clinical complications that may affect the operation's success.

Lens and Cataract

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Author :
Publisher : Amer Academy of Ophthalmology
ISBN 13 : 9781615253005
Total Pages : 273 pages
Book Rating : 4.2/5 (53 download)

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Book Synopsis Lens and Cataract by : James C. Bobrow, M.d.

Download or read book Lens and Cataract written by James C. Bobrow, M.d. and published by Amer Academy of Ophthalmology. This book was released on 2012-06 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews the anatomy, physiology, embryology and pathology of the lens. Covers the epidemiology, evaluation and management of cataracts; gives an overview of lens and cataract surgery; and explores the complications and special situations of cataract surgery. CME Information The American Academy of Ophthalmology is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The American Academy of Ophthalmology designates this enduring material for a maximum of 10 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. The American Medical Association requires that all learners participating in activities involving enduring materials complete a formal assessment before claiming CME credit. To assess your achievement in this activity and ensure that a specified level of knowledge has been reached, a posttest for this Section of the Basic and Clinical Science Course is provided. A minimum score of 80% must be obtained to pass the test and claim CME credit. Visit CME Central for more information. Major revision 2012-2013; 258 pages Section chair: James C. Bobrow, MD

Clinical Procedures in Primary Eye Care

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Publisher : Butterworth-Heinemann
ISBN 13 : 9780750688963
Total Pages : 0 pages
Book Rating : 4.6/5 (889 download)

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Book Synopsis Clinical Procedures in Primary Eye Care by : David B. Elliott

Download or read book Clinical Procedures in Primary Eye Care written by David B. Elliott and published by Butterworth-Heinemann. This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work describes, in a step-by-step way, how to perform the most commonly-used procedures in the primary eye care setting. With its practical approach, it demystifies the subject and is a useful manual for all students and practitioners requiring an introduction to diagnostic and treatment procedures.

Role of Cholesterol 25 Hydroxylase in Fibrotic Posterior Capsular Opacification

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Publisher :
ISBN 13 :
Total Pages : 98 pages
Book Rating : 4.6/5 (846 download)

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Book Synopsis Role of Cholesterol 25 Hydroxylase in Fibrotic Posterior Capsular Opacification by : Joseph M. Stevenson

Download or read book Role of Cholesterol 25 Hydroxylase in Fibrotic Posterior Capsular Opacification written by Joseph M. Stevenson and published by . This book was released on 2020 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Posterior capsular opacification (PCO), a common fibrotic complication of cataract surgery, is a disease which arises from epithelial to mesenchymal transition (EMT) of residual lens epithelial cells (LECs) within the lens capsule. The cells migrate toward the posterior capsule and form scar tissue, obstructing the visual axis and forming a secondary cataract. Ocular inflammatory signaling post cataract surgery (PCS) precedes EMT and predisposes remaining LECs to fibrotic differentiation, but specific interactions within the eye are largely unknown. CH25H (cholesterol-25 hydroxylase) is robustly upregulated in LECs as early as 3 hours PCS but its function in ocular inflammation and fibrosis is unknown. To study the function of CH25H within the lens, CH25H knockout mice were bred and lens fiber cells removed to simulate cataract surgery and assess post-surgical responses. Lenses lacking CH25H develop normally, but both the inflammatory and fibrotic responses to simulated cataract surgery are attenuated compared to wildtype (WT) lenses as they exhibit decreased levels of cytokines, fibrotic markers, and proliferation in response to surgery. This provides evidence to support a proposed reduction in NFÎðB signaling and AP-1 signaling in absence of CH25H - a relationship that has not yet been confirmed and will require further study. Fibrotic markers ÎłSMA and fibronectin upregulate sharply in WT LECs PCS, while CH25H null mice exhibit greatly attenuated fibrotic expression as well as significantly reduced LEC proliferation. Interestingly, mice lacking CH25H show unaltered infiltration of neutrophils at 24 hours PCS and macrophages at 3 days PCS, while circulating leukocytes are similar to WT mice, suggesting that CH25H is not necessary for innate leukocyte regulation or trafficking to the lens PCS. Taken together, its impact on inflammatory and fibrotic pathway induction suggests a role for CH25H as a mediator of the early wound-healing response, EMT, and subsequent fibrotic PCO.

Ocular Pathology

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Publisher :
ISBN 13 :
Total Pages : 792 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Ocular Pathology by : Myron Yanoff

Download or read book Ocular Pathology written by Myron Yanoff and published by . This book was released on 2002 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new, 5th Edition of the premier ocular pathology resource offers the latest information in the field. Over 2095 illustrations *1800 in full color* from the authors' collections represent one of the finest compilations of rare and unusual ocular conditions available. Comprehensive, yet concise, it explores new topics such as complications of corneal surgery, vascular disorders, secondary cataracts, bone-marrow transplant retinopathy, neural retinal detachment, ocular melanotic tumors, and more. Plus, a companion CD-ROM and text/CD-ROM package are available! Explores new topics such as complications of corneal surgery, vascular disorders, secondary cataracts, bone-marrow transplant retinopathy, neural retinal detachment, and ocular melanotic tumors (including diabetes). Offers expanded coverage of entities such as chromosome 17 deletion syndrome, necrobiotic xanthogranuloma, climatic protoglycan stromal keratopathy, unilateral acute idiopathic maculopathy, acute mutifocal retinitis, idiopathic polypoidal choroidal vasculopathy, North Carolina macular dystrophy, familial internal limiting membrane dystrophy, clumped pigmentary retinal dystrophy (clumped pigmentary retinal degeneration), vasoproliferative retinal tumors, Schwartz's syndrome, familial amyloidotic polyneuropathy, familial atypical mole and melanoma (FAM-M) syndrome, and more! Features specific genetic profiles for many existing entities.

Biomaterials and Regenerative Medicine in Ophthalmology

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Publisher : Elsevier
ISBN 13 : 184569743X
Total Pages : 565 pages
Book Rating : 4.8/5 (456 download)

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Book Synopsis Biomaterials and Regenerative Medicine in Ophthalmology by : Traian Chirila

Download or read book Biomaterials and Regenerative Medicine in Ophthalmology written by Traian Chirila and published by Elsevier. This book was released on 2009-12-18 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: With an increasingly aged population, eye diseases are becoming more widespread. Biomaterials have contributed in recent years to numerous medical devices for the restoration of eyesight, improving many patients’ quality of life. Consequently, biomaterials and regenerative medicine are becoming increasingly important to the advances of ophthalmology and optometry. Biomaterials and regenerative medicine in ophthalmology reviews the present status and future direction of biomaterials and regenerative medicine in this important field.Part one discusses applications in the anterior segment of the eye with chapters on such topics as advances in intraocular lenses (IOLs), synthetic corneal implants, contact lenses, and tissue engineering of the lens. Part two then reviews applications in the posterior segment of the eye with such chapters on designing hydrogels as vitreous substitutes, retinal repair and regeneration and the development of tissue engineered membranes. Chapters in Part three discuss other pertinent topics such as hydrogel sealants for wound repair in ophthalmic surgery, orbital enucleation implants and polymeric materials for orbital reconstruction.With its distinguished editor and international team of contributors, Biomaterials and regenerative medicine in ophthalmology is a standard reference for scientists and clinicians, as well as all those concerned with this ophthalmology. Reviews the increasingly important role of biomaterials and regenerative medicine in the advancement of ophthalmology and optometry Provides an overview of the present status and future direction of biomaterials and regenerative medicine in this important field Discusses applications in both the anterior and prosterior segments of the eye with chapters on such topics as synthetic corneal implants and retinal repair and regeneration

The Massachusetts Eye and Ear Infirmary Illustrated Manual of Ophthalmology

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1416061754
Total Pages : 661 pages
Book Rating : 4.4/5 (16 download)

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Book Synopsis The Massachusetts Eye and Ear Infirmary Illustrated Manual of Ophthalmology by : Neil J. Friedman

Download or read book The Massachusetts Eye and Ear Infirmary Illustrated Manual of Ophthalmology written by Neil J. Friedman and published by Elsevier Health Sciences. This book was released on 2009-01-01 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: With high quality color images combined with up-to-date treatment guidelines and a proven template, the third edition of The Massachusetts Eye and Ear Infirmary Illustrated Manual of Ophthalmology is a vital companion for every ophthalmic trainee, primary care practitioner and emergency trauma unit. The bonus PDA software allows you to access the entire contents of the manual on the go. Provides thorough, easily accessible and up-to-date information for all common eye disorders, creating an all-in-one resource for quick diagnosis and treatment. Uses highlighted emergency management boxes for a clear presentation of the crucial treatment of critical situations. Follows a templated format with key boxes highlighting important information. Presents full-color photographs throughout so you can compare real case presentations for more accurate diagnosis. Orders chapters anatomically (not by ophthalmic subspecialty) making it easier to locate the desired information by looking at the effected area. Provides a complete and thorough update with expanded sections, including age related macular degeneration, diabetic retinopathy, uveitis, glaucoma, dry eye, and refractive surgeries. Incorporates over 100 new high quality clinical color photos plus spectral domain OCT, CT scan, fluorescein angiogram, visual field, and corneal topography images. Adds brand new appendices outlining basic eye care and differential diagnosis information to help minimize wasted time in the clinic. Offers immediate and convenient access to the whole manual when on the go with bonus PDA software.

Anatomy ;Ocular physiology ;Biochemistry and genetics ;Pathology ;Microbiology ;Immunology ;Growth and senescence ;Optics ;Therapeutics ;Lasers and instrument technology ;Basic biostatistical and epidemiological terms

Download Anatomy ;Ocular physiology ;Biochemistry and genetics ;Pathology ;Microbiology ;Immunology ;Growth and senescence ;Optics ;Therapeutics ;Lasers and instrument technology ;Basic biostatistical and epidemiological terms PDF Online Free

Author :
Publisher : OUP Oxford
ISBN 13 : 0199584990
Total Pages : 285 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis Anatomy ;Ocular physiology ;Biochemistry and genetics ;Pathology ;Microbiology ;Immunology ;Growth and senescence ;Optics ;Therapeutics ;Lasers and instrument technology ;Basic biostatistical and epidemiological terms by : Louise Bye

Download or read book Anatomy ;Ocular physiology ;Biochemistry and genetics ;Pathology ;Microbiology ;Immunology ;Growth and senescence ;Optics ;Therapeutics ;Lasers and instrument technology ;Basic biostatistical and epidemiological terms written by Louise Bye and published by OUP Oxford. This book was released on 2013-05-23 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: An indispensable and fully comprehensive textbook, this covers the basic sciences in ophthalmology and is the only book you need to pass the FRCOphth Part 1 exam.

High Resolution Imaging in Microscopy and Ophthalmology

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Publisher : Springer
ISBN 13 : 3030166384
Total Pages : 407 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis High Resolution Imaging in Microscopy and Ophthalmology by : Josef F. Bille

Download or read book High Resolution Imaging in Microscopy and Ophthalmology written by Josef F. Bille and published by Springer. This book was released on 2019-08-13 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.

Pediatric Cataract Surgery

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 146983135X
Total Pages : 969 pages
Book Rating : 4.4/5 (698 download)

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Book Synopsis Pediatric Cataract Surgery by : M. Edward Wilson

Download or read book Pediatric Cataract Surgery written by M. Edward Wilson and published by Lippincott Williams & Wilkins. This book was released on 2014-01-06 with total page 969 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although uncommon, the occurrence of cataracts in very young patients can result in significant impairment—and can lead to blindness. This practical guide delivers need-to-know information to help clinicians treat pediatric patients with cataracts with a range of therapies and essential guidance on the management of complications. Explore the only reference devoted exclusively to pediatric cataract management! • 13 new chapters highlight the latest advances in bilateral cataract surgery, intraocular heparin treatment, treatment of traumatic cataracts, pre- and postoperative management, and techniques appropriate for patients in developing nations. • 4 hours of online procedural video accompany the text—giving readers a clinician’s view of essential procedures. A great way to refine technique, improve outcomes, avoid pitfalls, and manage potential complications. • Quick-reference format helps readers locate vital information at a glance.

Lee's Ophthalmic Histopathology

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Publisher : Springer Science & Business Media
ISBN 13 : 1447124766
Total Pages : 486 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Lee's Ophthalmic Histopathology by : Fiona Roberts

Download or read book Lee's Ophthalmic Histopathology written by Fiona Roberts and published by Springer Science & Business Media. This book was released on 2013-11-12 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated third edition of Lee’s Ophthalmic Histopathology, this well-illustrated and practically-oriented text has retained its general layout and style and division into specimen-based chapters. The visual image remains key to explaining the pathological processes - facilitated by full colour photography throughout the text. The text and illustrations are also provided as a searchable CD-ROM. The book emphasizes pertinent recent advances, particularly in the molecular basis of disease and in the diagnosis and classification of tumours. including improvements in immunohistochemistry and cytogenetic and molecular biological studies. This book is an invaluable source of reference for ophthalmic pathologists, general pathologists and ophthalmologists.

Intraocular Lenses with Surfaces Functionalized by Biomolecules in Relation with Lens Epithelial Cell Adhesion

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (92 download)

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Book Synopsis Intraocular Lenses with Surfaces Functionalized by Biomolecules in Relation with Lens Epithelial Cell Adhesion by : Yi-Shiang Huang

Download or read book Intraocular Lenses with Surfaces Functionalized by Biomolecules in Relation with Lens Epithelial Cell Adhesion written by Yi-Shiang Huang and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Posterior Capsular Opacification (PCO) is the capsule fibrosis developed onto the implanted IntraOcular Lens (IOL) by the de-differentiation of Lens Epithelial Cells (LEC) undergoing Epithelial-Mesenchymal Transition (EMT). Literature has shown that the incidence of PCO is multifactorial including patient's age or disease, surgical technique, and IOL design and material. Reports comparing hydrophilic and hydrophobic acrylic IOLs show the former has more severe PCO after EMT transition. Additionally, the LEC adhesion is favored onto the hydrophobic materials compared to the hydrophilic ones. A biomimetic strategy to promote LEC adhesion without de-differentiation to reduce PCO development risk is proposed. RGD peptides, as well as their grafting and quantification methods on a hydrophilic acrylic polymer were investigated. The surface functionalized IOL promoting LEC adhesion via integrin receptors can be used to reconstitute the capsule-LEC-IOL sandwich structure, which is considered to prevent PCO formation in literature. The results show the innovative biomaterial improves LEC adhesion, and also exhibits similar optical (light transmittance, optical bench) and mechanical (haptic compression force, IOL injection force) properties comparing to the starting material. In addition, comparing to the hydrophobic IOL material, this bioactive biomaterial exhibits similar abilities in LEC adhesion, morphology maintenance, and EMT biomarker expression. The in vitro assays suggest this biomaterial has the potential to reduce some risk factors of PCO development.

The Optimal Intraocular Lens for Patients

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (125 download)

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Book Synopsis The Optimal Intraocular Lens for Patients by : Christina Mastromonaco

Download or read book The Optimal Intraocular Lens for Patients written by Christina Mastromonaco and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Posterior capsular opacification (PCO) is the leading long-term complication of cataract surgery caused by the remnant lens epithelial cells (LECs) within the capsular bag. LECs undergo epithelial-to-mesenchymal transition (EMT) and acquire a myofibroblast phenotype, further depositing extracellular matrix, leading to opacities. Duration of intraocular lens (IOL) implant, patient comorbidities, and IOL type may be contributing factors to PCO. The aim of this study is to better understand the biocompatibility of the IOL within the eye, and determine the characteristics that led to PCO development. To do this, three main objectives will be pursued: 1) to compare different histopathological changes in the anterior segment between Anterior Chamber IOLs (ACIOLs) and Posterior Chamber IOLs (PCIOLs), 2) to assess the biological composition of PCO through objective immunohistochemical techniques in different PCIOL types, 3) to perform a retrospective analysis on a large cohort of specimens to analyse the IOL (optic edge design, material, haptics and filter) and patient factors (diabetic, hypertension, glaucoma and cancer) that are associated with lens decentration, ciliary ring distortion and PCO.In total, four hundred and forty donor eyes were obtained from the Minnesota Lions Eye Bank. All eyes came with clinical history of each patient including, age, sex, comorbidities, date of cataract surgery, and specific IOL model. Capsular bags with implanted IOLs were removed from the eye and digital images with the Olympus DSX 110 microscope were obtained. PCO was graded using previously published automated software (ADOS, Medical Parachute). After specimens were paraffin-embedded, 40 samples (ACIOL, PCIOL and phakic eyes) were stained with Masson’s trichrome, and further digitalized. Customized Medical Parachute TMAN software quantified the cellular components and the trabecular extracellular matrix (ECM) of the trabecular meshwork (TM). On another 190 PCIOL samples, automated immunohistochemistry with the Ventana Benchmark platform was performed using anti- Smooth Muscle Actin (SMA) to detect EMT, and anti-FN to detect fibronectin. Slides were digitalized and analysed using the Positive Pixel Count v9 algorithm. Extensive data were collected and a series of multivariate analysis were performed on the entire 440 samples. Statistical analyses were performed using STATA13, P value

The Wills Eye Hospital Atlas of Clinical Ophthalmology

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 078172774X
Total Pages : 512 pages
Book Rating : 4.7/5 (817 download)

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Book Synopsis The Wills Eye Hospital Atlas of Clinical Ophthalmology by : William Tasman

Download or read book The Wills Eye Hospital Atlas of Clinical Ophthalmology written by William Tasman and published by Lippincott Williams & Wilkins. This book was released on 2001 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The updated Second Edition of this atlas is the definitive pictorial guide to differential diagnosis and treatment of virtually every presenting condition seen in ophthalmologic practice. Specialists from the prestigious Wills Eye Hospital share their expertise in diagnosing and treating congenital and acquired disorders affecting the internal and external structures of the eye. The superb collection of 1,422 illustrations--1,217 in full color--includes sonograms, radiographs, clinical photographs, photomicrographs, and anatomic drawings. This edition features more information on stem cell and genetic research, more radiographic images and explanations of those findings, and descriptions of current methods of laser surgery. A CD-ROM based on this atlas is also available. See Media listing (Montzka) for details. The atlas and CD-ROM can be purchased together as a money-saving package. A Brandon-Hill recommended title.