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Lectin Microorganism Interactions
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Book Synopsis Lectin-Microorganism Interactions by : R. Doyle
Download or read book Lectin-Microorganism Interactions written by R. Doyle and published by CRC Press. This book was released on 1994-02-08 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides in-depth coverage of lectins and their interactions with micro-organisms and demonstrates how lectins function as probes for viral, bacterial, fungal and protozoal surfaces, as well as for blood group antigens.
Book Synopsis Lectin in Host Defense Against Microbial Infections by : Shie-Liang Hsieh
Download or read book Lectin in Host Defense Against Microbial Infections written by Shie-Liang Hsieh and published by Springer Nature. This book was released on 2020-03-09 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systemically presents the latest research on lectins, covering all the major topics in the field, including the heterocomplex of lectins and Toll-like receptors, protective versus pathogenic functions in connection with microbial infections, and novel strategies for enhancing host immunity against infectious diseases caused by viruses, bacteria, and fungi. Lectins are a large group of glycan-binding proteins that recognize diverse glycan and non-glycan structures expressed on prokaryotic and eukaryotic cells, and are vital to cell-cell interactions, the attachment of microbes to host cells, and the recognition and activation of immune responses to exogenous and endogenous danger signals. The composition and structure of microbes are complex and include numerous ‘pathogen-associated molecular patterns’ or ‘damage-associated molecular patterns’. As such, microbes’ interactions with immune cells activate multiple innate immunity receptors and produce distinct inflammatory reactions, which can be protective to contain microbial invasion, or pathogenic to cause tissue damage and shock syndrome in the host. The book shares lessons learned from state-of-the art research in this field, highlights the latest discoveries, and provides insightful discussions on lectin-mediated inflammatory reactions, while also outlining future research directions.
Book Synopsis Essentials of Glycobiology by : Ajit Varki
Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Book Synopsis Microbial Lectins and Agglutinins by : David Mirelman
Download or read book Microbial Lectins and Agglutinins written by David Mirelman and published by Wiley-Interscience. This book was released on 1986 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial lectins, proteins that make it possible for microbes to adhere to surfaces, have been identified as the major determinant of virulence in the infection of plants, animals, and humans, and are involved in a wide variety of cell-cell interactions. This contributed volume brings together for the first time information, much of it heretofore unpublished, which represents the most current knowledge of the subject. The book contains many illustrations and an extended table of microbial species with their associated lectins and agglutinins.
Download or read book Lectins written by Arpad Pusztai and published by CRC Press. This book was released on 1995-04-27 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lectins form a ubiquitous and important class of natural carbohydrate- binding information proteins. Although the main scientific interest was originally focussed on toxic lectins such as ricin, recent emphasis has shifted to exploring their involvement in cell-to-cell communication and recognition in microorganisms, plants and animals.; As knowled
Download or read book Plant Lectins written by A. Pusztai and published by Cambridge University Press. This book was released on 1991 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume surveys the chemistry, biochemistry, biosynthesis, metabolism and pharmacological properties of lectins. Lectins, which are most commonly found in plants, are widespread natural products with striking biological activities. Their specific ability to recognise and bind to simple or complex saccharides facilitates their role as effective information protein molecules. As agents of cell-to-cell recognition, lectins promote symbiosis between plants and specific nitrogen-fixing soil bacteria. As natural defensive molecules, they can protect plants against predators such as bacteria, fungi and insects. As part of our diet, lectins are powerful exogenous growth factors in the small intestine and influence our health, the digestive function and the bacterial ecology of the alimentary tract. Lectins are also important research tools in preparative biochemistry and cell science.
Book Synopsis Elucidation of the Host Cell Membrane Associated Interaction Partners of Pseudomonas Aeruginosa and Its Lectins (in Space and Time) by : Sahaja Aigal
Download or read book Elucidation of the Host Cell Membrane Associated Interaction Partners of Pseudomonas Aeruginosa and Its Lectins (in Space and Time) written by Sahaja Aigal and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Pseudomonas aeruginosa produces an abundance of virulence factors that aid in the establishment of bacterial invasion and infection in mammalian host cells. In this work, we investigated the host cell membrane-associated proteins that interact with Pseudomonas aeruginosa (PAO1) and its lectins, LecA and LecB. We used human lung epithelial cell line, H1299 as the cellular model for all the experiments as this bacterium is one of the major causes of severe lung infection. We found a novel cytoskeletal interaction partner of PAO1, namely the septin GTPases. When H1299 cells were infected with the pathogen, we observed cage-like as well as an amorphous ensemble of septins around it. We also found that knockdown (KD) or perturbation of septin function led to an increase in intracellular bacterial load. Additionally, we observed that septin function perturbation resulted in a significant reduction (≥70%) of viable bacterial count in the cell culture supernatant after 4 h of bacterial stimulation. While the wild-type cells could restrict the infection by expelling the septin-caged bacterium out, the septin function perturbed cells were less efficient in doing so. Septins, therefore, have a protective role against PAO1 infection. We found another interaction partner of PAO1 via its galactose-binding lectin LecA in H1299 cells. We observed that LecA associated with flotillin-1, a lipid raft marker which performs the role of an endocytic molecule and an intracellular cargo trafficker. In addition, LecA and flotillin-1 co-immunoprecipitated- this prompted us to investigate lectin trafficking in the absence of flotillin-1. Knockout of flotillin-1 did not impair LecA binding or internalization, but induced marginal changes in trafficking and kinetics. However, the invasion of whole bacteria was reduced by 50% in the absence of flotillin-1. We also found two other interaction partners of the bacterium via its fucose-binding lectin, LecB. We performed preliminary investigations on LecB internalization and found the glycoprotein receptor-CD44, a marker for CLIC/GEEC endocytic pathway to be associated with it. Since most pathogen interactions with the host cells require host cell binding and receptor clustering, we studied briefly the possibility of LecB mediated CD44 clustering at different time points using dSTORM microscopy. Preliminary investigation revealed that CD44 receptor clustering increased by ~2-fold and at the same time, the mean cluster size d ...
Book Synopsis The Rhizobiaceae by : Herman P. Spaink
Download or read book The Rhizobiaceae written by Herman P. Spaink and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Rhizobiaceae, Molecular Biology of Model Plant-Associated Bacteria. This book gives a comprehensive overview on our present molecular biological knowledge about the Rhizobiaceae, which currently can be called the best-studied family of soil bacteria. For many centuries they have attracted the attention of scientists because of their capacity to associate with plants and as a consequence also to specifically modify plant development. Some of these associations are beneficial for the plant, as is the case for the Rhizobiaceae subgroups collectively called rhizobia, which are able to fix nitrogen in a symbiosis with the plant hosts. This symbiosis results in the fonnation of root or stem nodules, as illustrated on the front cover. In contrast, several Rhizobiaceae subgroups can negatively affect plant development and evoke plant diseases. Examples are Agrobacterium tumefaciens andA. rhizogenes which induce the formation of crown galls or hairy roots on the stems of their host plants, respectively (bottom panels on front cover). In addition to the obvious importance of studies on the Rhizobiaceae for agronomy, this research field has resulted in the discovery of many fundamental scientific principles of general interest, which are highlighted in this book. To mention three examples: (i) the discovery of DNA transfer of A.
Book Synopsis The Evolution of the Immune System by : Davide Malagoli
Download or read book The Evolution of the Immune System written by Davide Malagoli and published by Academic Press. This book was released on 2016-05-24 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors. Helps the reader gain a modern idea of the evolution of the immune systems in pluricellular organisms Provides a complete overview of the most studied and hot topics in comparative and evolutionary immunology Reflects the organisation of the immune system (cell-based, humoral [innate], humoral [adaptive]) without introducing further and misleading levels of organization Brings concepts and ideas on the evolution of the immune system to a wide readership
Book Synopsis Signal Molecules in Plants and Plant-Microbe Interactions by : Ben J.J. Lugtenberg
Download or read book Signal Molecules in Plants and Plant-Microbe Interactions written by Ben J.J. Lugtenberg and published by Springer. This book was released on 1989-12-22 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the NATO Advanced Research Workshop on Molecular Signals in Microbe-Plant Symbiotic and Pathogenic Systems, held at Biddinghuizen, The Netherlands, May 21-26, 1989
Book Synopsis Advances in Biological Science Research by : Surya Nandan Meena
Download or read book Advances in Biological Science Research written by Surya Nandan Meena and published by Academic Press. This book was released on 2019-05-17 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Biological Science Research: A Practical Approach provides discussions on diverse research topics and methods in the biological sciences in a single platform. This book provides the latest technologies, advanced methods, and untapped research areas involved in diverse fields of biological science research such as bioinformatics, proteomics, microbiology, medicinal chemistry, and marine science. Each chapter is written by renowned researchers in their respective fields of biosciences and includes future advancements in life science research. Discusses various research topics and methods in the biological sciences in a single platform Comprises the latest updates in advanced research techniques, protocols, and methods in biological sciences Incorporates the fundamentals, advanced instruments, and applications of life science experiments Offers troubleshooting for many common problems faced while performing research experiments
Book Synopsis Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds by : Evandro Fei Fang
Download or read book Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds written by Evandro Fei Fang and published by Springer. This book was released on 2015-04-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The modern unhealthy diet and lifestyle in conjunction with pathogens, environmental carcinogens and multiple other risk factors increase humans’ susceptibility to different diseases exemplified by elevated levels of cancers, cardiovascular and communicable diseases. Screening of potential drugs from medicinal plants and animals provides a promising strategy for the alleviation of the impact of these diseases. Components with potential medicinal applications include RIPs, RNases, lectins, protease inhibitors and numerous small compounds. These compounds have shown both preventive and therapeutic effects for humans. This book is a compilation of articles written by internationally renowned experts exploring the different uses of medicinal compounds in human therapeutics. Here we provide a comprehensive outlook on both qualitative and quantitative studies focusing on medicinal plants and animals, and establishing a link between laboratory research discovery and clinical applications.
Book Synopsis The Specificity of Serological Reactions by : Karl Landsteiner
Download or read book The Specificity of Serological Reactions written by Karl Landsteiner and published by Courier Corporation. This book was released on 2013-09-25 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nobel prizewinner's account of experiments he and colleagues carried out on antigens and serological reactions with simple compounds. Exceptionally broad coverage of basic immunology. Extensive bibliography.
Book Synopsis Freshwater Microbiology by : David C. Sigee
Download or read book Freshwater Microbiology written by David C. Sigee and published by John Wiley & Sons. This book was released on 2005-09-27 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique textbook takes a broad look at the rapidly expanding field of freshwater microbiology. Concentrating on the interactions between viruses, bacteria, algae, fungi and micro-invertebrates, the book gives a wide biological appeal. Alongside conventional aspects such as phytoplankton characterisation, seasonal changes and nutrient cycles, the title focuses on the dynamic and applied aspects that are not covered within the current textbooks in the field. Complete coverage of all fresh water biota from viruses to invertebrates Unique focus on microbial interactions including coverage of biofilms, important communities on all exposed rivers and lakes. New information on molecular and microscopical techniques including a study of gene exchange between bacteria in the freshwater environment. Unique emphasis on the applied aspects of freshwater microbiology with particular emphasis on biodegradation and the causes and remediation of eutrophication and algal blooms.
Book Synopsis Bacterial Pathogenesis: Interaction of pathogenic bacteria with host cells by : Virginia L. Clark
Download or read book Bacterial Pathogenesis: Interaction of pathogenic bacteria with host cells written by Virginia L. Clark and published by Gulf Professional Publishing. This book was released on 1994 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Molecular Genetics of Plant-Microbe Interactions, Vol.1 by : H. Hennecke
Download or read book Advances in Molecular Genetics of Plant-Microbe Interactions, Vol.1 written by H. Hennecke and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on the interaction between plants and microbes has attracted considerable attention in recent years. The use of modem genetic techniques has now made possible a detailed analysis both of plant and of microbial genes involved in phytopathogenic and beneficial interactions. At the biochemical level, signal molecules and their receptors, either of plant or of microbial origins, have been detected which act in signal transduction pathways or as co-regulators of gene expression. We begin to understand the molecular basis of classical concepts such as gene-for-gene relationships, hypersensitive response, induced resistance, to name just a few. We realize, and will soon exploit, the tremendous potential of the results of this research for practical application, in particular to protect crop plants against diseases and to increase crop yield and quality. This exclung field of research, which is also of truly interdisciplinary nature, is expanding rapidly. A Symposium series has been devoted to it which began in 1982. Recently, the 5th International Symposium on the Molecular Genetics of Plant-Microbe Interactions was held in Interlaken, Switzerland. It brought together 640 scientists from almost 30 different countries who reported their latest research progress in 47 lectures, 10 short oral presentations, and on over 400 high-quality posters. This book presents a collection of papers that comprehensively reflect the major areas under study, explain novel experimental approaches currently in use, highlight significant advances made over the last one or two years but also emphasize the obstacles still ahead of us.
