Laughing Gas Viagra And Lipitor

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Laughing Gas, Viagra, and Lipitor

Author : Jie Jack Li
Publisher : Oxford University Press
ISBN 13 : 0199885281
Total Pages : 336 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis Laughing Gas, Viagra, and Lipitor by : Jie Jack Li

Download or read book Laughing Gas, Viagra, and Lipitor written by Jie Jack Li and published by Oxford University Press. This book was released on 2006-09-07 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The stories behind drug discovery are fascinating, full of human and scientific interest. This is a book on the history of drug discovery that highlights the intellectual splendor of discoverers as well as the human frailty associated them. History is replete with examples of breakthrough medicines that have saved millions of lives. Ether as an anesthetic by Morton; penicillin as an antibiotic by Fleming; and insulin as an anti-diabetic by Banting are just a few examples. The discoverers of these medicines are doubtlessly benefactors to mankind--for instance, without penicillin, 75% of us probably would not be alive because some of our parents or grandparents would have succumbed to infections. Dr. Jack Li, a medicinal chemist who is intimately involved with drug discovery, has assembled an astounding amount of facts and information behind important drugs through extensive literature research and interviews with many inventors of the drugs including Viagra and Lipitor. There have been many myths and inaccuracies associated with those legendary drugs. The inventors perspectives afforded this book an invaluable accuracy and insight because history is not history unless it is true. The text is supplemented by many anecdotes, pictures and postage stamps. Both specialist and layman will find Laughing Gas, Viagra, and Lipitor informative and entertaining. Students in chemistry, pharmacy, and medicine, workers in healthcare and high school science teachers will find this book most useful.

Laughing Gas, Viagra, and Lipitor

Author : Jie Jack Li
Publisher : Oxford University Press
ISBN 13 : 9780195345766
Total Pages : 336 pages
Book Rating : 4.3/5 (457 download)

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Book Synopsis Laughing Gas, Viagra, and Lipitor by : Jie Jack Li

Top Drugs

Author : Jie Jack Li
Publisher : Oxford University Press
ISBN 13 : 0199362599
Total Pages : 240 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Top Drugs by : Jie Jack Li

Download or read book Top Drugs written by Jie Jack Li and published by Oxford University Press. This book was released on 2015-07-31 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drugs like Lipitor, Plavix, Taxol, and Zoloft are integral in today's medicinal world. These widely used products save lives and improve the quality of lives, playing a crucial role in everything from cholesterol management to cancer treatment. These advances in medicine were brought into existence after nuanced process of creation, featuring a wide range of chemical and pharmacological experimentation and discovery. Top Drugs: Their History, Pharmacology, and Synthesis provides an in-depth study on ten prominent drugs, outlining the chemistry behind each one's creation. Jie Jack Li, a medicinal chemist and an expert on drug discovery, offers a thorough analysis of the landscape of current drug development. The comprehensive text is divided by health issues, including cardiovascular, cancer, metabolic diseases, and infectious diseases. Each section features individual chapters on significant drugs, outlining the chemistry and history of the drug's discovery. Li begins each chapter with the product's history, providing necessary context. Li then proceeds to describe the mechanism of action, structure-activity relationship (SAR), bioavailability, metabolism, toxicology, the discovery route, and the process route. Top Drugs: Their History, Pharmacology, and Synthesis will acclimate students, scientists, and interested laypersons to the world of chemistry and drug discovery.

Blockbuster Drugs

Author : Jie Jack Li
Publisher : Oxford University Press
ISBN 13 : 0199737681
Total Pages : 238 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Blockbuster Drugs by : Jie Jack Li

Download or read book Blockbuster Drugs written by Jie Jack Li and published by Oxford University Press. This book was released on 2014 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book uses the cases of several landmark drugs to discuss the history of the pharmaceutical industry, and discusses what could be next"--Provided by publisher.

Triumph of the Heart

Author : Jie Jack Li
Publisher : OUP USA
ISBN 13 : 0195323572
Total Pages : 220 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Triumph of the Heart by : Jie Jack Li

Download or read book Triumph of the Heart written by Jie Jack Li and published by OUP USA. This book was released on 2009-04-03 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prologue. 1. Cholesterol. 2. Genesis of Statins. 3. Merck's Triumph. 4. Discovery of Lipitor. 5. Development of Lipitor. 6. To Market, To Market. 7. Baycol, Crestor, and Drugs beyond Statins. 8. Reflections. Appendix. Trademarks of the Drugs. Bibliography and Notes. Index.

The SAGE Encyclopedia of Economics and Society

Author : Frederick F. Wherry
Publisher : SAGE Publications
ISBN 13 : 150630088X
Total Pages : 1984 pages
Book Rating : 4.5/5 (63 download)

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Book Synopsis The SAGE Encyclopedia of Economics and Society by : Frederick F. Wherry

Download or read book The SAGE Encyclopedia of Economics and Society written by Frederick F. Wherry and published by SAGE Publications. This book was released on 2015-09-01 with total page 1984 pages. Available in PDF, EPUB and Kindle. Book excerpt: Economics is the nexus and engine that runs society, affecting societal well-being, raising standards of living when economies prosper or lowering citizens through class structures when economies perform poorly. Our society only has to witness the booms and busts of the past decade to see how economics profoundly affects the cores of societies around the world. From a household budget to international trade, economics ranges from the micro- to the macro-level. It relates to a breadth of social science disciplines that help describe the content of the proposed encyclopedia, which will explicitly approach economics through varied disciplinary lenses. Although there are encyclopedias of covering economics (especially classic economic theory and history), the SAGE Encyclopedia of Economics and Society emphasizes the contemporary world, contemporary issues, and society. Features: 4 volumes with approximately 800 signed articles ranging from 1,000 to 5,000 words each are presented in a choice of print or electronic editions Organized A-to-Z with a thematic Reader's Guide in the front matter groups related entries Articles conclude with References & Future Readings to guide students to the next step on their research journeys Cross-references between and among articles combine with a thorough Index and the Reader's Guide to enhance search-and-browse in the electronic version Pedagogical elements include a Chronology of Economics and Society, Resource Guide, and Glossary This academic, multi-author reference work will serve as a general, non-technical resource for students and researchers within social science programs who seek to better understand economics through a contemporary lens.

From Bench to Market

Author : Walter Cabri
Publisher : Oxford University Press, USA
ISBN 13 : 9780198503835
Total Pages : 292 pages
Book Rating : 4.5/5 (38 download)

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Book Synopsis From Bench to Market by : Walter Cabri

Download or read book From Bench to Market written by Walter Cabri and published by Oxford University Press, USA. This book was released on 2000 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: '... a unique book... I highly recommendthis book to process chemists not only in the pharmaceutical industry but in the fine chemical, agrochemical, and colour chemical industries, too ... It is refreshing to see the book in paperback at a low cost. Highly recommended- I will certainly use it as a teaching aid' Chemistry in BritainWho wins the race to turn molecules into medicines? How much does it cost? What factors influence the choice of synthetic routes and reaction mechanisms? How can pharmaceutical companies protect their discoveries? In From Bench to Market, Walter Cabri and Romano Di Fabio chart the process of industrial chemical synthesis, from the first discovery of a molecule to its entry in the marketplace as a drug. Using real case histories of drug development from several therapeutic areas, they discuss all aspects related to the process research for bulk production, including comparison between different synthetic routes, key methodologies and reaction mechanisms, costs, patent competition, and crystalline forms.

Nature's Chemicals

Author : Richard Firn
Publisher : Oxford University Press on Demand
ISBN 13 : 0199566836
Total Pages : 261 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis Nature's Chemicals by : Richard Firn

Download or read book Nature's Chemicals written by Richard Firn and published by Oxford University Press on Demand. This book was released on 2010 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first monograph to describe Natural Products (NPs) as a group in an evolutionary context. It synthesizes a widely dispersed literature and provides a general picture of natural products encompassing evolution, history, ecology, and environmental issues, along with some deeper theory relevant to biochemistry.

Good Chemistry

Author : Alex Baenninger
Publisher : McGraw Hill Professional
ISBN 13 : 9780071426176
Total Pages : 200 pages
Book Rating : 4.4/5 (261 download)

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Book Synopsis Good Chemistry by : Alex Baenninger

Download or read book Good Chemistry written by Alex Baenninger and published by McGraw Hill Professional. This book was released on 2004 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of Valium by Roche Pharmaceutical and the entire benzodiazepine group of active substances was among the greatest accomplishments in 20th-century pharmacology. Good Chemistry combines a detailed account of this momentous development with an engaging biography of Leo Sternbach, the brilliant chemist who invented Valium and whose achievements heralded the beginning of a new era in research and therapeutics. This thought-provoking biographical history: Tells the fascinating life story of one of the 20th century's premier chemists Traces the developments that led to the invention of Valium Provides a cultural history of Valium and its impact on society

Drug Discovery and Development

Author : Ramarao Poduri
Publisher : Springer Nature
ISBN 13 : 9811555346
Total Pages : 522 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Drug Discovery and Development by : Ramarao Poduri

Download or read book Drug Discovery and Development written by Ramarao Poduri and published by Springer Nature. This book was released on 2021-02-15 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing. Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.

The Australian Drug Guide

Author : Jonathan Upfal
Publisher : Black Inc.
ISBN 13 : 9781863951746
Total Pages : 836 pages
Book Rating : 4.9/5 (517 download)

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Book Synopsis The Australian Drug Guide by : Jonathan Upfal

Download or read book The Australian Drug Guide written by Jonathan Upfal and published by Black Inc.. This book was released on 2006 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every year up to 140,000 Australians are rushed to hospital due to medication errors and misunderstandings. The new 2006 edition of The Australian Drug Guidecontains over 800 pages of up-to-the-minute information that could mean the difference between life and death for you or someone you know. You'll find the answers to all your questions about the medicines prescribed for you and your family in The Australian Drug Guide. It's you and your family's 'health insurance' in one easy-to-use reference.

Physicochemical Basis of Pharmaceuticals

Author : Humphrey Moynihan
Publisher : Oxford University Press, USA
ISBN 13 : 0199232849
Total Pages : 316 pages
Book Rating : 4.1/5 (992 download)

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Book Synopsis Physicochemical Basis of Pharmaceuticals by : Humphrey Moynihan

Download or read book Physicochemical Basis of Pharmaceuticals written by Humphrey Moynihan and published by Oxford University Press, USA. This book was released on 2009-07-23 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: What are the physical and chemical properties that determine how a drug interacts with the body? What determines which dosage form is best, if it will reach its intended target, and how it will be metabolised once it has entered the body? The Physicochemical Basis of Pharmaceuticals explores the phenomena which affect the formulation and bio-availability of drug substances to give a straightforward, accessible treatment of the essential concepts affecting the absorption and distribution of drugs. It provides the reader with the conceptual 'tool-kit' necessary to understand the physicochemical aspects of drug design and action, and shows how these concepts apply in practice. The book introduces key underlying physical chemistry principles before exploring pharmaceutical solutions, the pharmaceutical solid phase, solid - liquid dispersal systems, biological interfaces, absorption, distribution, metabolism and excretion, to give a complete view of the field. Focusing at all times on the essential principles and concepts, The Physicochemical Basis of Pharmaceuticals avoids excessive detail, presenting the key facts, backed up with pertinent examples and easy-to-digest illustrations, making it the ideal primer for those who need to understand physicochemical issues in the context of their broader field of study. Online Resource Centre For registered adopters of the text: · Figures from the book in electronic format, ready to download For students: · A hyperlinked bibliography of references given in the text.

Breakthrough

Author : Francine Jacobs
Publisher : Dissertation.com
ISBN 13 : 9780595328499
Total Pages : 0 pages
Book Rating : 4.3/5 (284 download)

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Book Synopsis Breakthrough by : Francine Jacobs

Download or read book Breakthrough written by Francine Jacobs and published by Dissertation.com. This book was released on 2004-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first complete account for young readers of the development of the first wonder drug, penicillin, and of the men and women who took part in this extraordinary project. It provides a background for understanding the significance of this breakthrough and the new direction it gave to medical science. Breakthrough: The True Story of Penicillin won the New York Academy of Sciences fifteenth Annual Children's Science Book Award.

Antifragile

Author : Nassim Nicholas Taleb
Publisher : Random House
ISBN 13 : 0679645276
Total Pages : 545 pages
Book Rating : 4.6/5 (796 download)

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Book Synopsis Antifragile by : Nassim Nicholas Taleb

Download or read book Antifragile written by Nassim Nicholas Taleb and published by Random House. This book was released on 2012-11-27 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antifragile is a standalone book in Nassim Nicholas Taleb’s landmark Incerto series, an investigation of opacity, luck, uncertainty, probability, human error, risk, and decision-making in a world we don’t understand. The other books in the series are Fooled by Randomness, The Black Swan, Skin in the Game, and The Bed of Procrustes. Nassim Nicholas Taleb, the bestselling author of The Black Swan and one of the foremost thinkers of our time, reveals how to thrive in an uncertain world. Just as human bones get stronger when subjected to stress and tension, and rumors or riots intensify when someone tries to repress them, many things in life benefit from stress, disorder, volatility, and turmoil. What Taleb has identified and calls “antifragile” is that category of things that not only gain from chaos but need it in order to survive and flourish. In The Black Swan, Taleb showed us that highly improbable and unpredictable events underlie almost everything about our world. In Antifragile, Taleb stands uncertainty on its head, making it desirable, even necessary, and proposes that things be built in an antifragile manner. The antifragile is beyond the resilient or robust. The resilient resists shocks and stays the same; the antifragile gets better and better. Furthermore, the antifragile is immune to prediction errors and protected from adverse events. Why is the city-state better than the nation-state, why is debt bad for you, and why is what we call “efficient” not efficient at all? Why do government responses and social policies protect the strong and hurt the weak? Why should you write your resignation letter before even starting on the job? How did the sinking of the Titanic save lives? The book spans innovation by trial and error, life decisions, politics, urban planning, war, personal finance, economic systems, and medicine. And throughout, in addition to the street wisdom of Fat Tony of Brooklyn, the voices and recipes of ancient wisdom, from Roman, Greek, Semitic, and medieval sources, are loud and clear. Antifragile is a blueprint for living in a Black Swan world. Erudite, witty, and iconoclastic, Taleb’s message is revolutionary: The antifragile, and only the antifragile, will make it. Praise for Antifragile “Ambitious and thought-provoking . . . highly entertaining.”—The Economist “A bold book explaining how and why we should embrace uncertainty, randomness, and error . . . It may just change our lives.”—Newsweek

The Amazing Language of Medicine

Author : Robert B. Taylor
Publisher : Springer
ISBN 13 : 3319503286
Total Pages : 238 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis The Amazing Language of Medicine by : Robert B. Taylor

Download or read book The Amazing Language of Medicine written by Robert B. Taylor and published by Springer. This book was released on 2017-01-23 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book tells the intriguing and often colorful stories of the medical words we use. The origins of clinical and scientific terms can be found in Greek and Latin myths, in places such as jungles of Uganda and the islands of the Aegean Sea, in the names of medicine’s giants such as Hippocrates and Osler, and in some truly unlikely sources. In this book you will learn the answers to questions such as: • What disease was named for an American space flight? • Do you know the echoic word for elephantine rumbling of the bowels? • What drug name was determined by drawing chemists’ notes out of a hat? • What are surfer’s eye, clam digger’s itch, and hide porter’s disease? This book can give you new insights into the terms we use every day in the clinic, hospital, and laboratory. Knowing a word’s history assists in understanding not only what it means, but also some of the connotative subtleties of terms used in diagnosis and treatment. The Amazing Language of Medicine is intended for the enrichment of physicians, other health professionals, students, and anyone involved in clinical care and medical science.

Irreversible Electroporation in Clinical Practice

Author : Martijn R. Meijerink
Publisher : Springer
ISBN 13 : 3319551132
Total Pages : 285 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Irreversible Electroporation in Clinical Practice by : Martijn R. Meijerink

Download or read book Irreversible Electroporation in Clinical Practice written by Martijn R. Meijerink and published by Springer. This book was released on 2017-12-27 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the clinical use of irreversible electroporation (IRE) – better known by its commercial name, NanoKnife – which is one of the most exciting new needle-guided cancer treatments. The coverage includes the history of IRE, general technique, preclinical research, applications in clinical practice and early clinical results, and future perspectives. Contraindications, treatment planning, potential complications, follow-up imaging, and other practical aspects are fully discussed, with highlighting of useful tips and tricks. Through the delivery of short but highly intense electrical pulses, IRE results in tumor cell membrane permeabilization, causing cells to go into apoptosis. The minimally invasive nature of IRE, combined with the prospect of completely eradicating tumors while preserving delicate structures in the ablation zone, makes IRE the object of worldwide clinical research. This book will be of value for practitioners and trainees in interventional and diagnostic radiology, surgery, medical oncology, HPB and gastroenterology, urology, and radiation oncology.

Modern Organic Synthesis in the Laboratory

Author : Jie Jack Li
Publisher : Oxford University Press
ISBN 13 : 9780198040637
Total Pages : 224 pages
Book Rating : 4.0/5 (46 download)

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Book Synopsis Modern Organic Synthesis in the Laboratory by : Jie Jack Li

Download or read book Modern Organic Synthesis in the Laboratory written by Jie Jack Li and published by Oxford University Press. This book was released on 2007-09-10 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Searching for reaction in organic synthesis has been made much easier in the current age of computer databases. However, the dilemma now is which procedure one selects among the ocean of choices. Especially for novices in the laboratory, it becomes a daunting task to decide what reaction conditions to experiment with first in order to have the best chance of success. This collection intends to serve as an "older and wiser lab-mate" one could have by compiling many of the most commonly used experimental procedures in organic synthesis. With chapters that cover such topics as functional group manipulations, oxidation, reduction, and carbon-carbon bond formation, Modern Organic Synthesis in the Laboratory will be useful for both graduate students and professors in organic chemistry and medicinal chemists in the pharmaceutical and agrochemical industries.