Laboratory Animals

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Use of Laboratory Animals in Biomedical and Behavioral Research

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309038391
Total Pages : 113 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Use of Laboratory Animals in Biomedical and Behavioral Research by : National Research Council

Download or read book Use of Laboratory Animals in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Guide for the Care and Use of Laboratory Animals

Author : Institute of Laboratory Animal Resources (U.S.). Committee on Care and Use of Laboratory Animals
Publisher :
ISBN 13 :
Total Pages : 84 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by : Institute of Laboratory Animal Resources (U.S.). Committee on Care and Use of Laboratory Animals

Download or read book Guide for the Care and Use of Laboratory Animals written by Institute of Laboratory Animal Resources (U.S.). Committee on Care and Use of Laboratory Animals and published by . This book was released on 1978 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Background Lesions in Laboratory Animals E-Book

Author : Elizabeth Fiona McInnes
Publisher : Elsevier Health Sciences
ISBN 13 : 0702049247
Total Pages : 256 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Background Lesions in Laboratory Animals E-Book by : Elizabeth Fiona McInnes

Download or read book Background Lesions in Laboratory Animals E-Book written by Elizabeth Fiona McInnes and published by Elsevier Health Sciences. This book was released on 2011-10-24 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Background Lesions in Laboratory Animals will be an invaluable aid to pathologists needing to recognize background and incidental lesions while examining slides taken from laboratory animals in acute and chronic toxicity studies, or while examining exotic species in a diagnostic laboratory. It gives clear descriptions and illustrations of the majority of background lesions likely to be encountered. Many of the lesions covered are unusual and can be mistaken for treatment-related findings in preclinical toxicity studies. The Atlas has been prepared with contributions from experienced toxicological pathologists who are specialists in each of the laboratory animal species covered and who have published extensively in these areas. over 600 high-definition, top-quality color photographs of background lesions found in rats, mice, dogs, minipigs, non-human primates, hamsters, guinea pigs and rabbits a separate chapter on lesions in the reproductive systems of all laboratory animals written by Dr Dianne Creasy, a world expert on testicular lesions in laboratory animals a chapter on common artifacts that may be observed in histological glass slides extensive references to each lesion described aging lesions encountered in all laboratory animal species, particularly in rats in mice which are used for carcinogenicity studies

Nutrient Requirements of Laboratory Animals,

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309051266
Total Pages : 188 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Nutrient Requirements of Laboratory Animals, by : National Research Council

Download or read book Nutrient Requirements of Laboratory Animals, written by National Research Council and published by National Academies Press. This book was released on 1995-02-01 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.

Laboratory Animal Anaesthesia

Author : Paul Flecknell
Publisher : Academic Press
ISBN 13 : 9780080918990
Total Pages : 304 pages
Book Rating : 4.9/5 (189 download)

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Book Synopsis Laboratory Animal Anaesthesia by : Paul Flecknell

Download or read book Laboratory Animal Anaesthesia written by Paul Flecknell and published by Academic Press. This book was released on 2009-04-09 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Animal Anesthesia looks at recent significant developments in anesthetic practices in laboratory experiments involving animals. It also provides information about basic standards for proper use of anesthesia. In addition, it examines the equipment and different anesthetic agents that are used in performing an experiment on animals. The book also discusses the profound effects of anesthesia on the physiological aspect of the animals’ body systems, such as hypothermia and respiratory depression. The book addresses the proper management and care that should be provided for the animals that undergo anesthesia. Furthermore, it covers different anesthetic procedures that should be used on various kinds of small animals intended for laboratory experiments. The main goal of this book is to provide information about the different anesthetic agents used in experiments, and the proper standards to follow when using anesthetics on lab animals. • New edition provides new information on anesthesia and analgesia, and has an extensively revised and updated bibliography • Provides a balanced consideration of the needs of scientific research and the welfare of laboratory animals • Written by a veterinary anesthetist and scientist with over 30 years' experience in the field, and who is actively engaged in research in this area • Provides rapid, easily accessed information using tabulated summaries • Provides those with limited experience of anesthesia with the information they need to carry our procedures effectively, safely, and humanely • Provides sufficient depth for the more experienced anesthetist moving to this field

Gnotobiotics

Author : Trenton R Schoeb
Publisher : Academic Press
ISBN 13 : 0128045833
Total Pages : 428 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Gnotobiotics by : Trenton R Schoeb

Download or read book Gnotobiotics written by Trenton R Schoeb and published by Academic Press. This book was released on 2017-08-11 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gnotobiotics summarizes and analyzes the research conducted on the use of gnotobiotes, providing detailed information regarding actual facility operation and derivation of gnotobiotic animals. In response to the development of new tools for microbiota and microbiome analysis, the increasing recognition of the various roles of microbiota in health and disease, and the consequent expanding demand for gnotobiotic animals for microbiota/microbiome related research, this volume collates the research of this expanding field into one definitive resource. Reviews and defines gnotobiotic animal species Analyzes microbiota in numerous contexts Presents detailed coverage of the protocols and operation of a gnotobiotic facility

Behavioral Biology of Laboratory Animals

Author : Kristine Coleman
Publisher : CRC Press
ISBN 13 : 0429671296
Total Pages : 1088 pages
Book Rating : 4.4/5 (296 download)

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Book Synopsis Behavioral Biology of Laboratory Animals by : Kristine Coleman

Download or read book Behavioral Biology of Laboratory Animals written by Kristine Coleman and published by CRC Press. This book was released on 2021-08-11 with total page 1088 pages. Available in PDF, EPUB and Kindle. Book excerpt: CHOICE Highly Recommended title, 2022! This 30-chapter volume informs students and professionals about the behavioral biology of animals commonly housed in laboratory and other captive settings. Each species evolved under specific environmental conditions, resulting in unique behavioral patterns, many of which are maintained in captivity even after generations of breeding. Understanding natural behavior is therefore a critical part of modern animal care practices. The descriptions, data, guidance, resources, and recommendations in this book will help the reader understand their animals better, refine the care and treatment that they receive, and improve the well-being, welfare, and wellness of their animals. The book is divided into three sections, all focusing on aspects of the behavioral biology of animals found in laboratories and related research settings. After five introductory chapters, 25 chapters are dedicated to specific taxonomic groups (including mice, zebrafish, zebra finches, reptiles, macaques) while a concluding section of ethograms provides a centralized resource for those interested in understanding, and potentially quantifying, animal behavior. The Behavioral Biology of Laboratory Animals will provide anyone working in maintenance, care, and/or research programs that involve laboratory animals with information about the way the animals live in the wild, and the way that they should live in captive research settings. Many of the guidelines and recommendations will also be valuable to those managing and working with animals in other environments, including zoological parks, aquaria, and sanctuaries.

Laboratory Animal Welfare

Author : Kathryn Bayne
Publisher : Academic Press
ISBN 13 : 0123851041
Total Pages : 336 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Laboratory Animal Welfare by : Kathryn Bayne

Download or read book Laboratory Animal Welfare written by Kathryn Bayne and published by Academic Press. This book was released on 2013-09-02 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Animal Welfare provides a comprehensive, up-to-date look into the new science of animal welfare within laboratory research. Animals specifically considered include rodents, cats and dogs, nonhuman primates, agricultural animals, avian animals and aquatic animals. The book examines the impact of experiment design and environment on animal welfare, as well as emergency situations and euthanasia practices. Readers will benefit from a review of regulations and policy guidelines concerning lab animal use, as well as information on assessing animal welfare. With discussions of the history and ethics of animals in research, and a debate on contemporary and international issues, this book is a go-to resource for laboratory animal welfare.

Guide for the Care and Use of Laboratory Animals

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309154006
Total Pages : 246 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by : National Research Council

Download or read book Guide for the Care and Use of Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 2011-01-27 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Guidelines for the Humane Transportation of Research Animals

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309101107
Total Pages : 165 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guidelines for the Humane Transportation of Research Animals by : National Research Council

Download or read book Guidelines for the Humane Transportation of Research Animals written by National Research Council and published by National Academies Press. This book was released on 2006-08-14 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arranging the transportation of animals at research facilities is often an ordeal. There is a confusing patchwork of local, national, and international regulations; a perceived lack of high-quality shipping services; a dearth of science-based good practices; and a lack of biosafety standards. It's a challenge â€"and an impediment to biomedical research. Guidelines for the Humane Transportation of Research Animals identifies the current problems encountered in the transportation of research animals and offers recommendations aimed at local and federal officials to rectify these problems. This book also includes a set of good practices based on the extensive body of literature on transportation of agricultural animals, universal concepts of physiology, and a scientific understanding of species-specific needs and differences. Good practices were developed by the committee to address thermal environment, space requirements, food and water requirements, social interaction, monitoring of transportation, emergency procedures, personnel training, and biosecurity. Guidelines for the Humane Transportation of Research Animals is an essential guide for all researchers, animal care technicians, facilities managers, administrators, and animal care and use committees at research institutions.

Flynn's Parasites of Laboratory Animals

Author : David G. Baker
Publisher : John Wiley & Sons
ISBN 13 : 0470344172
Total Pages : 844 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Flynn's Parasites of Laboratory Animals by : David G. Baker

Download or read book Flynn's Parasites of Laboratory Animals written by David G. Baker and published by John Wiley & Sons. This book was released on 2008-01-09 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prepared under the auspices of the American College of Laboratory Animal Medicine, this second edition has been thoroughly updated and revised to improve utility and readability. The book is now organized by vertebrate host species, with parasites presented phylogenetically within chapters. Additional highlights of this edition include introductory chapters on modern diagnostic techniques and parasite biology, and a new appendix features a complete drug formulary. The well-presented and extensively illustrated volume addresses all aspects of laboratory animal parasites. Regarded as the most comprehensive and authoritative work available on the topic, this book is an essential reference for veterinary parasitologists, clinicians, students and laboratory animal scientists.

Laboratory Animals

Author : Javier Guillen
Publisher : Academic Press
ISBN 13 : 012849879X
Total Pages : 466 pages
Book Rating : 4.1/5 (284 download)

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Book Synopsis Laboratory Animals by : Javier Guillen

Download or read book Laboratory Animals written by Javier Guillen and published by Academic Press. This book was released on 2017-11-03 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Animals: Regulations and Recommendations for the Care and Use of Animals in Research, Second Edition, is the only publication to offer a global compilation of standards on the care, welfare and use of animals in research. The book provides updated information that will be of great interest to professionals across laboratory animal science and biomedical research. Users will find a broad picture of the regulations required in other areas of the world that will be essential to appropriately manage animal care and use programs. Offers a worldwide view and global compilation of regulations, guidelines and recommendations for laboratory animal research Provides insight into factors that play key roles in the regulatory framework for countries and geographic regions Compares and contrasts regulations in different regions Written in layman’s terms to easily understand legislation and regulations

The Laboratory Mouse

Author : Hans Hedrich
Publisher : Academic Press
ISBN 13 : 012382009X
Total Pages : 868 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis The Laboratory Mouse by : Hans Hedrich

Download or read book The Laboratory Mouse written by Hans Hedrich and published by Academic Press. This book was released on 2012-06-14 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Laboratory Mouse, Second Edition is a comprehensive book written by international experts. With inclusions of the newly revised European standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields. Features four-color illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research Offers additional chapters on new mouse strains, phenotyping of strains, bacteria and parasites, and immunology Includes the newly revised EU standards on care, as well as, comparisons to standards and regulations in the US and other countries

Laboratory Animal Medicine

Author : James G. Fox
Publisher : Academic Press
ISBN 13 : 1483269167
Total Pages : 766 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Laboratory Animal Medicine by : James G. Fox

Download or read book Laboratory Animal Medicine written by James G. Fox and published by Academic Press. This book was released on 2013-10-02 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Animal Medicine is a compilation of papers that deals with the diseases and biology of major species of animals used in medical research. The book discusses animal medicine, experimental methods and techniques, design and management of animal facilities, and legislation on laboratory animals. Several papers discuss the biology and diseases of mice, hamsters, guinea pigs, and rabbits. Another paper addresses the dog and cat as laboratory animals, including sourcing of these animals, housing, feeding, and their nutritional needs, as well as breeding and colony management. The book also describes ungulates as laboratory animals, including topics on sourcing, husbandry, preventive medical treatments, and housing facilities. One paper addresses primates as test animals, covering the biology and diseases of old world primates, Cebidae, and ferrets. Some papers pertain to the treatment, diseases, and needed facilities for birds, amphibians, and fish. Other papers then deal with techniques of experimentation, anesthesia, euthanasia, and some factors (spontaneous diseases) that complicate animal research. The text can prove helpful for scientists, clinical assistants, and researchers whose work involves laboratory animals.

Electrocardiography of Laboratory Animals

Author : Jeffrey W. Richig
Publisher : Academic Press
ISBN 13 : 0124159990
Total Pages : 144 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Electrocardiography of Laboratory Animals by : Jeffrey W. Richig

Download or read book Electrocardiography of Laboratory Animals written by Jeffrey W. Richig and published by Academic Press. This book was released on 2013-11-22 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrocardiography of Laboratory Animals is the only book covering electrocardiography of laboratory animals, including dogs, mini-pigs, and cynomologus monkeys. As more countries institute requirements for the care of laboratory animals in research, this publication offers an effective standard on performing and analyzing ECGs. Topics covered include safety electrocardiography, toxicology, safety pharmacology, and telemetry. Electrocardiography of Laboratory Animals will assist biological and medical researchers, veterinarians, zoologists, and students in understanding electrocardiography of various species of animals used in research. Covers safety electrocardiography of large laboratory animals Offers comprehensive analysis of ECGs for practical laboratory use Includes a self-evaluation section for testing of ECG reading and analysis

The Laboratory Rat

Author : George J. Krinke
Publisher : Elsevier
ISBN 13 : 9780080533469
Total Pages : 756 pages
Book Rating : 4.5/5 (334 download)

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Book Synopsis The Laboratory Rat by : George J. Krinke

Download or read book The Laboratory Rat written by George J. Krinke and published by Elsevier. This book was released on 2000-06-20 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference series will provide all researchers using laboratory animals with comprehensive practical information on the various species. Each title in the series is devoted to a particular species, and draws together all available data in a "one-stop", easily accessible source. Each has similar format, with sections on the strains available, their husbandry, and special diets. Also included are sections on gross anatomy, endocrinology, and reproduction, followed by more detailed sections on neuroanatomy, vasculature, cell biology, and histology of particular organs and structures, and a section on molecular biology. High quality illustrations are included throughout and a color plate section is provided. A glossary, list of equipment suppliers, and "Quick Reference Section" are added features. The "Quick Reference Section" brings together all tables from the text, allowing readers to find data swiftly. The first volume in The Handbook of Experimental Animals Series, The Laboratory Rat, provides researchers in academia and industry using laboratory animals with comprehensive, practical information on the species. The Laboratory Rat has been divided into eight sections dealing with: * Strains and their selection for research * Housing and maintenance * Pathogens and diseases * Breeding and reproduction * Anatomy * Physiology * Procedures, including experimental surgery * Emerging techniques, including genetic engineering and molecular technology Key Features * Provides a valuable, comprehensive reference source for anybody working with the laboratory rat * Formatted in a two-color, user-friendly layout * Includes high-quality illustrations throughout as well as a color plate section * Glossary * Tables in the text are also arranged into one Quick Reference Section for ease of access to the data * Appendix of equipment suppliers

The Clinical Chemistry of Laboratory Animals

Author : David M. Kurtz
Publisher : CRC Press
ISBN 13 : 142009114X
Total Pages : 1162 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis The Clinical Chemistry of Laboratory Animals by : David M. Kurtz

Download or read book The Clinical Chemistry of Laboratory Animals written by David M. Kurtz and published by CRC Press. This book was released on 2017-10-18 with total page 1162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Key features: Serves as the detailed, authoritative source of the clinical chemistry of the most commonly used laboratory animals Includes detailed chapters dedicated to descriptions of clinical chemistry-related topics specific to each laboratory species as well as organ/class-specific chapters Presents information regarding evaluation and interpretation of a variety of individual clinical chemistry end points Concludes with detailed chapters dedicated to descriptions of statistical analyses and biomarker development of clinical chemistry-related topics Provides extensive reference lists at the end of each chapter to facilitate further study Extensively updated and expanded since the publication of Walter F. Loeb and Fred W. Quimby’s second edition in 1999, the new The Clinical Chemistry of Laboratory Animals, Third Edition continues as the most comprehensive reference on in vivo animal studies. By organizing the book into species- and organ/class-specific chapters, this book provides information to enable a conceptual understanding of clinical chemistry across laboratory species as well as information on evaluation and interpretation of clinical chemistry data relevant to specific organ systems. Now sponsored by the American College of Laboratory Animal Medicine (ACLAM), this well-respected resource includes chapters on multiple laboratory species and provides pertinent information on their unique physiological characteristics, methods for sample collection, and preanalytical sources of variation for the particular species. Basic methodology for common procedures for each species is also discussed. New Chapters in the Third Edition Include: The Laboratory Zebrafish and Other Fishes Evaluation of Cardiovascular and Pulmonary Function and Injury Evaluation of Skeletal Muscle Function and Injury Evaluation of Bone Function and Injury Vitamins Development of Biomarkers Statistical Methods The Clinical Chemistry of Laboratory Animals, Third Edition is intended as a reference for use by veterinary students, clinical veterinarians, verterinary toxicologists, veterinary clinical pathologists, and laboratory animal veterinarians to aid in study design, collection of samples, and interpretation of clinical chemistry data for laboratory species.