Kinetic Investigation of the Molecular Processes Involved in the Mechanism of Open Complex Formation Between E. Coli RNA Polymerase and the [lambda]Pr Promoter

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ISBN 13 :
Total Pages : 200 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Kinetic Investigation of the Molecular Processes Involved in the Mechanism of Open Complex Formation Between E. Coli RNA Polymerase and the [lambda]Pr Promoter by : Wayne Kontur

Download or read book Kinetic Investigation of the Molecular Processes Involved in the Mechanism of Open Complex Formation Between E. Coli RNA Polymerase and the [lambda]Pr Promoter written by Wayne Kontur and published by . This book was released on 2006 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cumulated Index Medicus

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ISBN 13 :
Total Pages : 1340 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1996 with total page 1340 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Kinetic-mechanistic and DNA Footprinting Evidence for Large-scale Conformational Changes in Escherichia Coli RNA Polymerase and [lambda]Pr Promoter DNA in Open Complex Formation

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ISBN 13 :
Total Pages : 242 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Kinetic-mechanistic and DNA Footprinting Evidence for Large-scale Conformational Changes in Escherichia Coli RNA Polymerase and [lambda]Pr Promoter DNA in Open Complex Formation by : Caroline A. Davis

Download or read book Kinetic-mechanistic and DNA Footprinting Evidence for Large-scale Conformational Changes in Escherichia Coli RNA Polymerase and [lambda]Pr Promoter DNA in Open Complex Formation written by Caroline A. Davis and published by . This book was released on 2007 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Interaction of E. Coli RNA Polymerase with Lambda Phage PR Promoter

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ISBN 13 :
Total Pages : 430 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis The Interaction of E. Coli RNA Polymerase with Lambda Phage PR Promoter by : Won-Chul Suh

Download or read book The Interaction of E. Coli RNA Polymerase with Lambda Phage PR Promoter written by Won-Chul Suh and published by . This book was released on 1993 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Characterization by DNA Footprinting of Intermediates Involved in Transcription Initiation by Escherichia Coli E Sigma70 RNA Polymerase at the Lambda PR Promoter

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ISBN 13 :
Total Pages : 242 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Characterization by DNA Footprinting of Intermediates Involved in Transcription Initiation by Escherichia Coli E Sigma70 RNA Polymerase at the Lambda PR Promoter by : Marni Raffaelle

Download or read book Characterization by DNA Footprinting of Intermediates Involved in Transcription Initiation by Escherichia Coli E Sigma70 RNA Polymerase at the Lambda PR Promoter written by Marni Raffaelle and published by . This book was released on 2003 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mechanisms of Transcription

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Publisher : Springer Science & Business Media
ISBN 13 : 3642606911
Total Pages : 331 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Mechanisms of Transcription by : Fritz Eckstein

Download or read book Mechanisms of Transcription written by Fritz Eckstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of Transcription presents a unique perspective on the fundamental processes of transcription. A collection of distinguished authors draws together the underlying mechanisms involved in the process of transcription. This includes RNA polymerase function and its interaction with promoter sequences, and the structures of the various components on the transcriptional machinery. Both prokaryotic and eukaryotic systems, NMR and crystallographic structures of a number of important eukaryotic transcription factors are discussed, as well as the role of chromatin structure.

Lung Cancer

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ISBN 13 :
Total Pages : 1256 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Lung Cancer by : Harvey I. Pass

Download or read book Lung Cancer written by Harvey I. Pass and published by . This book was released on 2000 with total page 1256 pages. Available in PDF, EPUB and Kindle. Book excerpt: The all-new Second Edition of this groundbreaking volume reviews the results of today's most current breast cancer clinical trials worldwide and highlights the clinical implications of recent breakthroughs in translational and molecular research. The book helps practitioners make sense of the latest trial results and develop sound, evidence-based diagnostic and therapeutic strategies. Coverage includes clinical trial data published up to 2002 on all treatment modalities--including surgery, radiation, chemotherapy, and hormones--and comprehensive drug information to help clinicians choose the most appropriate chemotherapeutic regimen. Levels of evidence are indicated to help practitioners assess the weight of evidence on efficacy and toxicity for each treatment.

RNA Polymerases as Molecular Motors

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Publisher : Royal Society of Chemistry
ISBN 13 : 1847559980
Total Pages : 353 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis RNA Polymerases as Molecular Motors by : Henri Buc

Download or read book RNA Polymerases as Molecular Motors written by Henri Buc and published by Royal Society of Chemistry. This book was released on 2009-03-10 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cell can be viewed as a 'collection of protein machines' and understanding these molecular machines requires sophisticated cooperation between cell biologists, geneticists, enzymologists, crystallographers, chemists and physicists. To observe these machines in action, researchers have developed entirely new methodologies for the detection and the nanomanipulation of single molecules. This book, written by expert scientists in the field, analyses how these diverse fields of research interact on a specific example - RNA polymerase. The book concentrates on RNA polymerases because they play a central role among all the other machines operating in the cell and are the target of a wide range of regulatory mechanisms. They have also been the subject of spectacular advances in their structural understanding in recent years, as testified by the attribution of the Nobel prize in chemistry in 2006 to Roger Kornberg. The book focuses on two aspects of the transcription cycle that have been more intensively studied thanks to this increased scientific cooperation - the recognition of the promoter by the enzyme, and the achievement of consecutive translocation steps during elongation of the RNA product. Each of these two topics is introduced by an overview, and is then presented by worldwide experts in the field, taking the viewpoint of their speciality. The overview chapters focus on the mechanism-structure interface and the structure-machine interface while the individual chapters within each section concentrate more specifically on particular processes-kinetic analysis, single-molecule spectroscopy, and termination of transcription, amongst others. Specific attention has been paid to the newcomers in the field, with careful descriptions of new emerging techniques and the constitution of an atlas of three-dimensional pictures of the enzymes involved. For more than thirty years, the study of RNA polymerases has benefited from intense cooperation between the scientific partners involved in the various fields listed above. It is hoped that a collection of essays from outstanding scientists on this subject will catalyse the convergence of scientific efforts in this field, as well as contribute to better teaching at advanced levels in Universities.

Protein-Nucleic Acid Interactions

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Publisher : Royal Society of Chemistry
ISBN 13 : 0854042725
Total Pages : 417 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis Protein-Nucleic Acid Interactions by : Phoebe A. Rice

Download or read book Protein-Nucleic Acid Interactions written by Phoebe A. Rice and published by Royal Society of Chemistry. This book was released on 2008-05-22 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides both in-depth background and up-to-date information in this area. The chapters are organized by general themes and principles, written by experts who illustrate topics with current findings. Topics covered include: - the role of ions and hydration in protein-nucleic acid interactions - transcription factors and combinatorial specificity - indirect readout of DNA sequence - single-stranded nucleic acid binding proteins - nucleic acid junctions and proteins, - RNA protein recognition - recognition of DNA damage. It will be a key reference for both advanced students and established scientists wishing to broaden their horizons.

Biomolecular Kinetics

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Publisher : CRC Press
ISBN 13 : 1351646664
Total Pages : 883 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Biomolecular Kinetics by : Clive R. Bagshaw

Download or read book Biomolecular Kinetics written by Clive R. Bagshaw and published by CRC Press. This book was released on 2017-10-04 with total page 883 pages. Available in PDF, EPUB and Kindle. Book excerpt: "a gem of a textbook which manages to produce a genuinely fresh, concise yet comprehensive guide" –Mark Leake, University of York "destined to become a standard reference.... Not just a ‘how to’ handbook but also an accessible primer in the essentials of kinetic theory and practice." –Michael Geeves, University of Kent "covers the entire spectrum of approaches, from the traditional steady state methods to a thorough account of transient kinetics and rapid reaction techniques, and then on to the new single molecule techniques" –Stephen Halford, University of Bristol This illustrated treatment explains the methods used for measuring how much a reaction gets speeded up, as well as the framework for solving problems such as ligand binding and macromolecular folding, using the step-by-step approach of numerical integration. It is a thoroughly modern text, reflecting the recent ability to observe reactions at the single-molecule level, as well as advances in microfluidics which have given rise to femtoscale studies. Kinetics is more important now than ever, and this book is a vibrant and approachable entry for anyone who wants to understand mechanism using transient or single molecule kinetics without getting bogged down in advanced mathematics. Clive R. Bagshaw is Emeritus Professor at the University of Leicester, U.K., and Research Associate at the University of California at Santa Cruz, U.S.A.

Physics in Molecular Biology

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Publisher : Cambridge University Press
ISBN 13 : 9780521844192
Total Pages : 328 pages
Book Rating : 4.8/5 (441 download)

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Book Synopsis Physics in Molecular Biology by : Kim Sneppen

Download or read book Physics in Molecular Biology written by Kim Sneppen and published by Cambridge University Press. This book was released on 2005-08-25 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, first published in 2005, is a discussion for advanced physics students of how to use physics to model biological systems.

The Antibiotic Resistome

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Publisher : Wiley
ISBN 13 : 9781118376737
Total Pages : 384 pages
Book Rating : 4.3/5 (767 download)

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Book Synopsis The Antibiotic Resistome by : Gerry Wright

Download or read book The Antibiotic Resistome written by Gerry Wright and published by Wiley. This book was released on 2016-08-22 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bacteriophage T4

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ISBN 13 :
Total Pages : 432 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Bacteriophage T4 by : Christopher K. Mathews

Download or read book Bacteriophage T4 written by Christopher K. Mathews and published by . This book was released on 1983 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Microbial Ecology Manual

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Publisher : Springer
ISBN 13 : 9400902158
Total Pages : 266 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Molecular Microbial Ecology Manual by : Antoon D. L. Akkermans

Download or read book Molecular Microbial Ecology Manual written by Antoon D. L. Akkermans and published by Springer. This book was released on 2014-01-13 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: For a long time microbial ecology has been developed as a distinct field within Ecology. In spite of the important role of microorganisms in the environment, this group of 'invisible' organisms remained unaccessable to other ecologists. Detection and identification of microorganisms remain largely dependent on isolation techniques and characterisation of pure cul tures. We now realise that only a minor fraction of the microbial com munity can be cultivated. As a result of the introduction of molecular methods, microbes can now be detected and identified at the DNA/RNA level in their natural environment. This has opened a new field in ecology: Molecular Microbial Ecology. In the present manual we aim to introduce the microbial ecologist to a selected number of current molecular techniques that are relevant in micro bial ecology. The first edition of the manual contains 33 chapters and an equal number of additional chapters will be added this year. Since the field of molecular ecology is in a continuous progress, we aim to update and extend the Manual regularly and will invite anyone to depo sit their new protocols in full detail in the next edition of this Manual. We hope this book finds its place where it was born: at the lab bench! Antoon D.L. Akkermans, Jan Dirk van Elsas and Frans J. de Bruijn March 1995 Molecular Microbial Ecology Manual 1.3.6: 1-8, 1996. © 1996 Kluwer Academic Publishers.

Molecular Biology of Bacteriophage T4

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Publisher : ASM Press
ISBN 13 :
Total Pages : 648 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Biology of Bacteriophage T4 by : Jim D. Karam

Download or read book Molecular Biology of Bacteriophage T4 written by Jim D. Karam and published by ASM Press. This book was released on 1994 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new text highlights the value of this biological system as a research and teaching tool. The book is a sequel to the 1983 edition and is organized into 6 major sections: DNA metabolism, regulation of gene expression, morphogenesis, structure of selected proteins, host–phage interactions, and laboratory experiments in T4 molecular genetics. Since T4 has played a central role in the development of molecular biology as an academic discipline, the themes presented in this book provide a framework for designing graduate and undergraduate courses in prokaryotic genetics and biochemistry.

Experiments with Gene Fusions

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ISBN 13 :
Total Pages : 332 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Experiments with Gene Fusions by : Thomas J. Silhavy

Download or read book Experiments with Gene Fusions written by Thomas J. Silhavy and published by . This book was released on 1984 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Epigenetic Gene Expression and Regulation

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Publisher : Academic Press
ISBN 13 : 0128004711
Total Pages : 484 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Epigenetic Gene Expression and Regulation by : Suming Huang

Download or read book Epigenetic Gene Expression and Regulation written by Suming Huang and published by Academic Press. This book was released on 2015-10-19 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. - Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies - Helps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspring - Chapters are replete with clinical examples to empower the basic biology with translational significance - Offers more than 100 illustrations to distill key concepts and decipher complex science