Kindling 4

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Kindling 4

Author : Juhn A. Wada
Publisher : Springer Science & Business Media
ISBN 13 : 1468457969
Total Pages : 471 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Kindling 4 by : Juhn A. Wada

Download or read book Kindling 4 written by Juhn A. Wada and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the proceedings of the fourth in a series of inter national gatherings on kindling held on the University of British Columbia campus, June 15-17, 1989. Since the last gath ering in 1985, kindling continues to attract an ever-increasing number of investigators as reflected by the phenomenal increase in the number of kindling-related research reports. No other acute or chronic model has been exploited so extensively using electrophysiological, pharmacological, biochemical and behav ioural approaches involving a variety of brain sites and ani mal species. The continuing search, during the past few years, for the mechanism underlying the enduring change induced by kindling is beginning to shed some light on aspects of its molecular basis and to suggest the future direction of research. The late Graham Goddard, the original kindler, would have been delighted with this development. We were all shocked and saddened by his tragic death, but his spirit is very much alive among all of us who gathered together to share new information and collectively reassess the present state of knowledge at this symposium. I must say that we miss him very, very much. We know he is happy in his heaven knowing that he accomplished more in a short lifetime than most and that his love for mankind, and life's challenges, remain as a legacy, and goal, for us all.

Jasper's Basic Mechanisms of the Epilepsies

Author : Jeffrey Noebels
Publisher : Oxford University Press
ISBN 13 : 0199842590
Total Pages : 1258 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis Jasper's Basic Mechanisms of the Epilepsies by : Jeffrey Noebels

Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey Noebels and published by Oxford University Press. This book was released on 2012-06-01 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: H.H. Jasper, A.A. Ward, A. Pope and H.H. Merritt, chair of the Public Health Service Advisory Committee on the Epilepsies, National Institutes of Health, published the first volume on Basic Mechanisms of the Epilepsies (BME) in 1969. Their ultimate goal was to search for a "better understanding of the epilepsies and seek more rational methods of their prevention and treatment." Since then, basic and clinical researchers in epilepsy have gathered together every decade and a half with these goals in mind -- assessing where epilepsy research has been, what it has accomplished, and where it should go. In 1999, the third volume of BME was named in honor of H.H. Jasper. In line with the enormous expansion in the understanding of basic epilepsy mechanisms over the past four decades, this fourth edition of Jasper's BME is the most ambitious yet. In 90 chapters, the book considers the role of interactions between neurons, synapses, and glia in the initiation, spread and arrest of seizures. It examines mechanisms of excitability, synchronization, seizure susceptibility, and ultimately epileptogenesis. It provides a framework for expanding the epilepsy genome and understanding the complex heredity responsible for common epilepsies as it explores disease mechanisms of ion channelopathies and developmental epilepsy genes. It considers the mechanisms of conditions of epilepsy comorbidities. And, for the first time, this 4th edition describes the current efforts to translate the discoveries in epilepsy disease mechanisms into new therapeutic strategies. This book, considered the 'bible' of basic epilepsy research, is essential for the student, the clinician scientist and all research scientists who conduct laboratory-based experimental epilepsy research using cellular, brain slice and animal models, as well as for those interested in related disciplines of neuronal oscillations, network plasticity, and signaling in brain strucutres that include the cortex, hippocampus, and thalamus. In keeping with the 1969 goals, the book is now of practical importance to the clinical neurologist and epileptologist as the progress of research in molecular genetics and modern efforts to design antiepileptic drugs, cures and repairs in the epilepsies converge and impact clinical care.

Kindling 01

Author : Kinfolk Kinfolk
Publisher : Kinfolk
ISBN 13 : 9781736264102
Total Pages : 120 pages
Book Rating : 4.2/5 (641 download)

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Book Synopsis Kindling 01 by : Kinfolk Kinfolk

Download or read book Kindling 01 written by Kinfolk Kinfolk and published by Kinfolk. This book was released on 2021-06-08 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new magazine for people with children, from the team behind Kinfolk. Kindling is a place to explore the new ideas and fresh perspectives that come with being a parent. It’s non-judgmental, unfussy and made to be enjoyed by anyone currently raising a child under the age of ten. We’re interested in exploring the big ideas around parenthood, not what your child should be having for dinner or wearing at the weekend. Compact and colorful, the magazine is designed to be kept and treasured—whether on a coffee table or a child’s bookshelf. Inside The Emotions Issue, you’ll find an interview with the professor of psychology who advised on Pixar’s Inside Out, a workbook geared towards helping your child talk about their feelings, and a photo essay in which fruits and vegetables bring common idioms to life. Just ask yourself: What would it really look like to be “cool as a cucumber”? Kindling is also packed with features and columns that answer questions including: What’s it like to spend four years traveling with your parents? What can the Gruffalo teach us about fatherhood? And how should you answer a child if they blindside you with a tough question like “Why do people die?”? Designed to be read by adults but shared with children, Kindling is brought to life through the playful drawings of Norwegian illustrator Espen Friberg, and contains an activity section packed with suggestions for fun, free and (occasionally) educational games that parents and children can enjoy together.

Advances in Stereotactic and Functional Neurosurgery 4

Author : F.J. Gillingham
Publisher : Springer Science & Business Media
ISBN 13 : 3709185920
Total Pages : 416 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Advances in Stereotactic and Functional Neurosurgery 4 by : F.J. Gillingham

Download or read book Advances in Stereotactic and Functional Neurosurgery 4 written by F.J. Gillingham and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thus instead of being synonymous with specific procedures per formed at the level of the basal ganglia, stereotaxis is in fact a general diagnostic and therapeutic concept, which has as its aim the precise three-dimensional representation of the patient's brain in its entirety. This three-dimensional representation is based on anatomical, neuro radiological and other localizing information, the spatial integration Prof. Jean Talairach with friends and coworkers at the congress dinner in the Royaumont Abbey near Paris. (From left to right: Drs.]. Bancaud, N.T. Zervas, B. Nashold,]. Talairach, G. Szikla, F. Mundinger, P. Tournoux,]. Peeker) of which allows a more precise "anatomical" approach to the human brain and to the surgical management of localized pathologic proces ses. Literally, stereotaxis means "orientation in space". Taken in this general sense, all surgical procedures obviously should be stereo tactic, at least in their principle! Two of the main themes of our meeting, namely the topic of the first day, "Surgery of Epilepsy" and that of the second "Stereotactic Cerebral Irradiation" of small brain tumours correspond to this evolution toward a global "whole brain" concept of stereotaxis. The same philosophy inspired the scientific efforts of the stereotactic group Introduction 3 of the Sainte Anne Hospital, under the leadership of its promoter, Professor Jean Talairach. This is the reason why the present Meeting is dedicated in honor of his scientific work.

Current Catalog

Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 690 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Catalog by : National Library of Medicine (U.S.)

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1992 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Legislative Documents

Author : Iowa
Publisher :
ISBN 13 :
Total Pages : 1134 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Legislative Documents by : Iowa

Download or read book Legislative Documents written by Iowa and published by . This book was released on 1906 with total page 1134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains the reports of state departments and officials for the preceding fiscal biennium.

Kindling 5

Author : Michael E. Corcoran
Publisher : Springer Science & Business Media
ISBN 13 : 146155375X
Total Pages : 507 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Kindling 5 by : Michael E. Corcoran

Download or read book Kindling 5 written by Michael E. Corcoran and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last Kindling Conference was organized by Dr. Juhn Wada and held at the Univer sity of British Columbia, Vancouver, B. C. , in 1989. In the intervening years, research on kin dling has proceeded at an explosive pace and significant advances have been made in our understanding of the molecular biological, anatomical, and physiological substrates of kin dling, as well as in our appreciation of the age-dependent effects and complex behavioral consequences of kindling, its sensitivity to drugs, and its relevance to the clinical epilepsies. In order to review these developments and to provide researchers with an opportunity to in teract face to face and discuss the issues that preoccupy us all, we organized the Fifth Interna tional Conference on Kindling, in Victoria, B. C. , in the summer of 1996. Most of the stalwarts in kindling research were invited, as were a number of investigators whose research on kindling has become prominent in the past few years. We continue to miss the late Graham Goddard, the discoverer of kindling, and were saddened by the recent death of Eric Lothman, a prolific researcher and clinician who would have been a prominent participant. We were deeply disturbed to learn of the death of Frank Morrell, one of the earliest kindlers and an eminent neurologist, who died several months after our conference.

Information Circular

Author :
Publisher :
ISBN 13 :
Total Pages : 1226 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Information Circular by :

Download or read book Information Circular written by and published by . This book was released on 1955 with total page 1226 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Annual Report on Factory Inspection

Author : New York (State). Bureau of Factory Inspection
Publisher :
ISBN 13 :
Total Pages : 888 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Annual Report on Factory Inspection by : New York (State). Bureau of Factory Inspection

Download or read book Annual Report on Factory Inspection written by New York (State). Bureau of Factory Inspection and published by . This book was released on 1900 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cumulated Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1574 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1976 with total page 1574 pages. Available in PDF, EPUB and Kindle. Book excerpt:

I Can Do That! Woodworking Projects

Author : David Thiel
Publisher : Penguin
ISBN 13 : 1440348200
Total Pages : 209 pages
Book Rating : 4.4/5 (43 download)

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Book Synopsis I Can Do That! Woodworking Projects by : David Thiel

Download or read book I Can Do That! Woodworking Projects written by David Thiel and published by Penguin. This book was released on 2016-09-29 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Build quality furniture fast and simple! Beginning woodworkers (or experienced woodworkers who are looking for a weekend project) can accomplish these builds quickly. • Each project requires minimal woodworking experience and only hand and portable power tools--no need for expensive equipment. • These projects use only readily available materials that are easily found at your local home center, saving you lots of time and a few headaches. • Within these pages you'll also find a helpful training manual for choosing and using recommended tools--it's the perfect guide for building your skills as a woodworker. • Learn to build a variety of tasteful and functional items for the home including furniture, shelving and storage.

Sensitization in the Nervous System

Author : Charles D. Barnes
Publisher : CRC Press
ISBN 13 : 104027840X
Total Pages : 320 pages
Book Rating : 4.0/5 (42 download)

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Book Synopsis Sensitization in the Nervous System by : Charles D. Barnes

Download or read book Sensitization in the Nervous System written by Charles D. Barnes and published by CRC Press. This book was released on 2024-11-01 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sensitization is a concept of learning and memory that has grown out of experiments on "simple" animals. Interest in sensitization has grown tremendously in the last several years, fueled mainly by evidence of the molecular basis of sensitization in invertebrates on the one hand and the study of cocaine abuse, which produces behavioral sensitization, on the other. Because the rapid advance of information across such a broad range of research areas has made an integrated approach necessary, this volume combines findings on sensitization across the phylogenetic scale.

Epilepsy: A Comprehensive Textbook

Author : Jerome Engel Jr
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975105532
Total Pages : 10135 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis Epilepsy: A Comprehensive Textbook by : Jerome Engel Jr

Download or read book Epilepsy: A Comprehensive Textbook written by Jerome Engel Jr and published by Lippincott Williams & Wilkins. This book was released on 2023-10-23 with total page 10135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authoritative and updated, Epilepsy: A Comprehensive Textbook, 3rd Edition, contains 365 chapters that cover the full spectrum of relevant topics in biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Written by world-renowned authorities and expertly edited by epileptologists Drs. Jerome Engel, Jr., Solomon L. Moshé, Aristea S. Galanopoulou, John M. Stern, Alexis Arzimanoglou, Jacqueline A. French, Renzo Guerrini, Andres M. Kanner, and Istvan Mody, this three-volume work includes detailed discussions of seizure types and epilepsy syndromes, relationships between physiology and clinical events, psychiatric and medical comorbidities, conditions that could be mistaken for epilepsy, and an increasing range of pharmacologic, surgical, and alternative therapies.

Annual Report

Author : Saint Louis (Mo.). Fire Dept
Publisher :
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Annual Report by : Saint Louis (Mo.). Fire Dept

Download or read book Annual Report written by Saint Louis (Mo.). Fire Dept and published by . This book was released on 1906 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Mayor's Message with Accompanying Documents, to the Municipal Assembly of the City of St. Louis ...

Author : Saint Louis (Mo.)
Publisher :
ISBN 13 :
Total Pages : 1076 pages
Book Rating : 4.0/5 (965 download)

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Book Synopsis The Mayor's Message with Accompanying Documents, to the Municipal Assembly of the City of St. Louis ... by : Saint Louis (Mo.)

Download or read book The Mayor's Message with Accompanying Documents, to the Municipal Assembly of the City of St. Louis ... written by Saint Louis (Mo.) and published by . This book was released on 1909 with total page 1076 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mayor's Message

Author : Saint Louis (Mo.)
Publisher :
ISBN 13 :
Total Pages : 1090 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Mayor's Message by : Saint Louis (Mo.)

Download or read book Mayor's Message written by Saint Louis (Mo.) and published by . This book was released on 1909 with total page 1090 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes reports of the heads of the various municipal departments.

Neuropharmacology Methods in Epilepsy Research

Author : Steven L. Peterson
Publisher : CRC Press
ISBN 13 : 9781420048889
Total Pages : 306 pages
Book Rating : 4.0/5 (488 download)

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Book Synopsis Neuropharmacology Methods in Epilepsy Research by : Steven L. Peterson

Download or read book Neuropharmacology Methods in Epilepsy Research written by Steven L. Peterson and published by CRC Press. This book was released on 2019-05-07 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is an estimated 2.5 million epileptics in the US and perhaps some 40 million worldwide. As research has become increasingly molecular in scope, fewer scientists are trained in the US on basic, integrated epilepsy techniques. One frustration in neuroscience today is the application of state-of-the-art molecular biology techniques to inappropriate animal models of epilepsy - frequently resulting in inconclusive results. Epilepsy research will be increasingly undertaken by scientists well-trained in reductionist methodology, but who may be unfamiliar with integrated, whole-animal techniques. This situation appears even more difficult considering there has been no updated textbook on experimental models of epilepsy over the last twenty years - until now. Neuropharmacology Methods in Epilepsy Research describes fundamental methodologies and procedures in this field, representing the only detailed text concerning experimental models of epilepsy published in the last 20 years. This guide studies the reproduction of well-characterized and readily interpretable experimental models of epilepsy to which state-of-the-art molecular biology techniques can be applied. Each chapter features: Introduction - providing a brief background and historical account of the techniques and their use Methodology - describing equipment, solutions, species, electrodes as well as considering variations of techniques and stimulation parameters Interpretations - demonstrating the relevance of techniques to epilepsy as well as describing what exactly is being studied and how the data is appropriately applied to understanding epilepsy Topics include electroshock, chemoconvulsions, kindling, audiogenic seizures, focal seizures, and brain slice preparations. Discussions also include: Recently developed seizure models, including status epilepticus and massed trial simulations Influence of circadian and diurnal rhythms on convulsive activity Behavior al and cognitive deficits associated with anticonvulsant drug testing Technical approaches, i.e. slice models, microdialysis techniques, intracranial implant surgery, audiogenic seizure testing, kindling paradigms, and the rhythmic nature of seizures This unique text provides a thorough reference for the diverse methodologies within this area of neuropharmacological research - providing the basis for on-going cellular and molecular investigations as well as novel therapeutic approaches to the treatment of epilepsy.