Isolation and Structure Elucidation of Bioactive Compounds (Dedicated to the memory of the late Professor Charles D. Hufford)

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Publisher : MDPI
ISBN 13 : 3038977802
Total Pages : 276 pages
Book Rating : 4.0/5 (389 download)

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Book Synopsis Isolation and Structure Elucidation of Bioactive Compounds (Dedicated to the memory of the late Professor Charles D. Hufford) by : Muhammad Ilias

Download or read book Isolation and Structure Elucidation of Bioactive Compounds (Dedicated to the memory of the late Professor Charles D. Hufford) written by Muhammad Ilias and published by MDPI. This book was released on 2019-04-11 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are very pleased to introduce the Book Version of our Special Issue in Molecules dedicated to the memory of the late Professor Dr. Charles D. Hufford. The issue has been a huge success, with 22 full-length peer-reviewed papers and a tribute by Professor Alice M.Clark. Authors, reviewers, and collaborators from many countries across the worldhave contributed to this endeavour, and we are truly grateful to all. This Special Issue isrepresentative of the broad impact that “Charlie” had on the field of bioactive naturalproducts. This Special Issue comprises papers from Professor Hufford’s former students,colleagues, and collaborators throughout the world who have utilized a wide array ofstate-of-the-art techniques to examine diverse natural sources to isolate and identify avariety of natural products with a wide spectrum of biological activities, including somenew microbial transformations and insights into bioactive molecules. Many new bioactive compounds are described and reported here for the first time. Bioactivities reportedinclude cytotoxicity, antimicrobial activity, anti-inflammatory activity, antileishmanialactivity, antitrypanosomal activity, antimalarial activity, analgesic activity, and beneficialliver activities, just to name a few. This Special Issue will undoubtedly have a lasting impact on the field of bioactive natural products, as exemplified by the career of Dr. Hufford. Lastly, without the timely and outstanding contributions from all of you, this Special Issue would not have been possible. We thank you all very much for your contributions and your time devoted to this Special Issue in memory of a special person. Finally, we express ourgratitude and thanks to the journal Molecules and their excellent team of expert reviewers for giving us the support and opportunity to make this Special Issue a huge success!

Isolation and Structure Elucidation of Bioactive Secondary Metabolites from Microbial Sources

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Publisher :
ISBN 13 :
Total Pages : 256 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Isolation and Structure Elucidation of Bioactive Secondary Metabolites from Microbial Sources by : Kate J. Graham

Download or read book Isolation and Structure Elucidation of Bioactive Secondary Metabolites from Microbial Sources written by Kate J. Graham and published by . This book was released on 1994 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial organisms often produce biologically active and chemically intriguing secondary metabolites. To isolate and characterize compounds of novel activity and structure, bioassay- guided fractionations were employed on a variety of natural products sources. Active compounds were characterized by spectroscopic analysis and X-ray diffraction methods. As a result of these studies, six projects were completed, resulting in the purification of a diverse range of compounds containing activity in a variety of assays. A coumarin and parahydroxyphenylethanol were determined to possess phytotoxic activity from fungal pathogens. Two novel C-glycosidic compounds from a bacterial plant pathogen were found to be the first low molecular weight elicitors of the hypersensitive response in plants. A verticillin of the epi-polythiodiketopiperazine class isolated from a soil fungus was discovered to be responsible for inhibition of ras farnesylation transferase. Leafcutter ants were found to be deterred by the presence of a novel sesqualterpenoid in epiphylls. Finally, inhibitors of the PDGF receptor were isolated and characterized from a lichen.

Medicinal Chemistry of Bioactive Natural Products

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Publisher : John Wiley & Sons
ISBN 13 : 0471739332
Total Pages : 482 pages
Book Rating : 4.4/5 (717 download)

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Book Synopsis Medicinal Chemistry of Bioactive Natural Products by : Xiao-Tian Liang

Download or read book Medicinal Chemistry of Bioactive Natural Products written by Xiao-Tian Liang and published by John Wiley & Sons. This book was released on 2006-03-17 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current discoveries and research into bioactive natural products Medicinal Chemistry of Bioactive Natural Products provides a much-needed survey of bioactive natural products and their applications in medicinal chemistry. This comprehensive reference features articles by some of the world's leading scientists in the field on discovery, structure elucidation, and elegant synthetic strategies--developed for natural products--with an emphasis on the structure activity relationship of bioactive natural products. The topics have been carefully chosen on the basis of relevance to current research and to importance as clinicially useful agents. Rather than attempting to be a comprehensive encyclopedia of bioactive natural products, Medicinal Chemistry of Bioactive Natural Products guides the reader to the key developments in the field. By providing not only practical detail but a historical perspective on the chemistry and biology of the compounds under consideration, the book serves as a handy resource for researchers in their own work developing pharmaceuticals, and as an inspiring introduction for young scientists to the dynamic field of bioactive natural products research. Enhanced by examples with updated research results, the discussion covers such topics as: * The chemistry and biology of epothilones * Vancomycin and other glycopeptide antibiotic derivates * Antitumor and other related activities of Taxol and its analogs * The antimalarial properties of the traditional Chinese medicine, Quinghaosu (artemisinin) * Huperzine A: A natural drug for the treatment of Alzheimer's disease * The medicinal chemistry of ginkgolides from Ginkgo biloba * Recent progress in Calophyllum coumarins as potent anti-HIV agents * Plant-derived anti-HIV agents and analogs * Chemical synthesis of annonaceous acetogenins and their structurally modified mimics

Alkaloids - Secrets of Life:

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Publisher : Elsevier
ISBN 13 : 9780080475332
Total Pages : 334 pages
Book Rating : 4.4/5 (753 download)

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Book Synopsis Alkaloids - Secrets of Life: by : Tadeusz Aniszewski

Download or read book Alkaloids - Secrets of Life: written by Tadeusz Aniszewski and published by Elsevier. This book was released on 2007-03-22 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alkaloids, represent a group of interesting and complex chemical compounds, produced by the secondary metabolism of living organisms in different biotopes. They are relatively common chemicals in all kingdoms of living organisms in all environments. Two hundred years of scientific research has still not fully explained the connections between alkaloids and life. Alkaloids-Chemistry, Biological Significance, Applications and Ecological Role provides knowledge on structural typology, biosynthesis and metabolism in relation to recent research work on alkaloids. Considering an organic chemistry approach to alkaloids using biological and ecological explanation. Within the book several questions that persist in this field of research are approached as are some unresearched areas. The book provides beneficial text for an academic and professional audience and serves as a source of knowledge for anyone who is interested in the fascinating subject of alkaloids. Each chapter features an abstract. Appendices are included, as are a listing of alkaloids, plants containing alkaloids and some basic protocols of alkaloid analysis. * Presents the ecological role of alkaloids in nature and ecosystems * Interdisciplinary and reader friendly approach * Up-to-date knowledge

Plant Breeding in the Omics Era

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Publisher : Springer
ISBN 13 : 3319205323
Total Pages : 249 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Plant Breeding in the Omics Era by : Rodomiro Ortiz Ríos

Download or read book Plant Breeding in the Omics Era written by Rodomiro Ortiz Ríos and published by Springer. This book was released on 2015-09-16 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​The field of plant breeding has grown rapidly in the last decade with breakthrough research in genetics and genomics, inbred development, population improvement, hybrids, clones, self-pollinated crops, polyploidy, transgenic breeding and more. This book discusses the latest developments in all these areas but explores the next generation of needs and discoveries including omics beyond genomics, cultivar seeds and intellectual and property rights. This book is a leading-edge publication of the latest results and forecasts important areas of future needs and applications.​

The Handbook of Cannabis Therapeutics

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Publisher : Routledge
ISBN 13 : 1136752854
Total Pages : 520 pages
Book Rating : 4.1/5 (367 download)

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Book Synopsis The Handbook of Cannabis Therapeutics by : Ethan B. Russo

Download or read book The Handbook of Cannabis Therapeutics written by Ethan B. Russo and published by Routledge. This book was released on 2014-05-22 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn the facts behind the pharmacology and pharmacokinetics of controversial cannabis therapeutics The Handbook of Cannabis Therapeutics: From Bench to Bedside sets aside the condemnation and hysteria of society’s view of cannabis to concentrate on the medically sound aspects of cannabis therapeutics. The world’s foremost experts provide a reasoned, thoroughly researched overview of the controversial subject of cannabis, from its history as a medicine through its latest therapeutic uses. The latest studies on the botany, history, biochemistry, pharmacology, toxicology, clinical use for various illnesses such as AIDS, epilepsy, and multiple sclerosis, and side effects of marijuana are all examined and discussed in depth. This comprehensive resource is a compendium of articles from the Journal of Cannabis Therapeutics—with additional contemporary commentary. It presents startling research that explores and supports the medicinal value of cannabis use and its derivatives as a valid therapeutic resource for pain and inflammation, for several illnesses less responsive to other therapies, and even for certain veterinary uses. Cannabinoids such as nabilone, THC, levonantradol, ajulemic acid, dexanabinal, and others are extensively described, with a review of new indications for cannabinoid pharmaceuticals. The book is carefully referenced to encourage your examination of previous studies and provides tables and figures to enhance understanding of information. The Handbook of Cannabis Therapeutics discusses: the uses of cannabis in Arabic, Greek, Roman, and early English medicines absorption rates pharmacokinetics pharmacodynamics separate extracts versus the use of cannabis in its entirety the therapeutic value of the endocannabinoid system cannabinoids and newborn feeding a comparison of smoking versus oral preparations clinical research data on eating cannabis therapeutic uses as appetite stimulant treatments in obstetrics and gynecology medicinal treatments used in Jamaica the use of cannabis in the treatment of multiple sclerosis the benefits versus the adverse side effects of cannabis use The Handbook of Cannabis Therapeutics is a reference work certain to become crucial to physicians, psychologists, researchers, biochemists, graduate students, and interested members of the public.

Special Issue in Honor of Professor James D. McChesney on the Occasion of His 80th Birthday

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Publisher :
ISBN 13 : 9783036527130
Total Pages : 262 pages
Book Rating : 4.5/5 (271 download)

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Book Synopsis Special Issue in Honor of Professor James D. McChesney on the Occasion of His 80th Birthday by : Muhammad Ilias

Download or read book Special Issue in Honor of Professor James D. McChesney on the Occasion of His 80th Birthday written by Muhammad Ilias and published by . This book was released on 2022 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants have been the sources of important pharmaceuticals, flavoring agents, and agrochemicals. The antimalarial drugs artemisinin and quinine; the anticancer drugs taxol, etoposide, and vinca alkaloids; the sugar-free sweetening agents stevioside and rebaudiosides; and antifeedant azadiractin are good examples of important plant-based drugs, food additives, and agrochemicals currently on the market. Despite these and many other successes, there are significant challenges to discovering and developing commercially important natural products from plants, such as procuring plant materials in large quantities, separating active constituents from complex mixtures, and undesirable qualities, such as low solubility or poor chemical or metabolic stability of active constituents. Dr. James D. McChesney has contributed immensely to overcoming the inherent challenges associated with discovering and developing products modeled from plant-based natural product leads. His research on artemisinin, taxol, galanthamine, podophyllotoxin, and stevia sweet glycosides exemplifies the magnitude of these contributions. His extensive work on the structural modification of taxol led to the discovery and development of the anticancer agent TPI 287, a third-generation taxane analog that is currently undergoing clinical trials. Dr. McChesney has had a long, distinguished teaching and research career, has authored more than 225 research publications, and holds more than 60 patents. He is a past president and Fellow of the American Society of Pharmacognosy and a Fellow of the AAAS. He has mentored many graduate students, post-docs, and junior faculty members who hold prominent positions in natural products research establishments in the US and worldwide. We wish to dedicate this Special Issue Book Version to celebrate the eightieth birthday of Dr. McChesney, a prolific thinker with abundant inventiveness in the field of natural product chemistry and pharmacognosy.

Alkaloid Chemistry

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Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Alkaloid Chemistry by : Manfred Hesse

Download or read book Alkaloid Chemistry written by Manfred Hesse and published by John Wiley & Sons. This book was released on 1981 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Progress in Botany 69

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Publisher : Springer Science & Business Media
ISBN 13 : 3540729542
Total Pages : 479 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Progress in Botany 69 by : Ulrich Lüttge

Download or read book Progress in Botany 69 written by Ulrich Lüttge and published by Springer Science & Business Media. This book was released on 2007-12-10 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: With one volume published each year, this series keeps scientists and students current with the latest developments and results in all areas of the plant sciences. This present volume includes insightful reviews covering genetics, cell biology, physiology, comparative morphology, systematics, ecology, and vegetation science.

Phytochemistry of Medicinal Plants

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Publisher : Springer Science & Business Media
ISBN 13 : 1489917780
Total Pages : 369 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Phytochemistry of Medicinal Plants by : John T. Arnason

Download or read book Phytochemistry of Medicinal Plants written by John T. Arnason and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemicals from medicinal plants are receiving ever greater attention in the scientific literature, in medicine, and in the world economy in general. For example, the global value of plant-derived pharmaceuticals will reach $500 billion in the year 2000 in the OECD countries. In the developing countries, over-the-counter remedies and "ethical phytomedicines," which are standardized toxicologically and clinically defined crude drugs, are seen as a promising low cost alternatives in primary health care. The field also has benefited greatly in recent years from the interaction of the study of traditional ethnobotanical knowledge and the application of modem phytochemical analysis and biological activity studies to medicinal plants. The papers on this topic assembled in the present volume were presented at the annual meeting of the Phytochemical Society of North America, held in Mexico City, August 15-19, 1994. This meeting location was chosen at the time of entry of Mexico into the North American Free Trade Agreement as another way to celebrate the closer ties between Mexico, the United States, and Canada. The meeting site was the historic Calinda Geneve Hotel in Mexico City, a most appropriate site to host a group of phytochemists, since it was the address of Russel Marker. Marker lived at the hotel, and his famous papers on steroidal saponins from Dioscorea composita, which launched the birth control pill, bear the address of the hotel.

Bioactive Natural Products

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Publisher : World Scientific
ISBN 13 : 9814335371
Total Pages : 695 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Bioactive Natural Products by : Goutam Brahmachari

Download or read book Bioactive Natural Products written by Goutam Brahmachari and published by World Scientific. This book was released on 2012 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations.

The Fuzziness in Molecular, Supramolecular, and Systems Chemistry

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Publisher :
ISBN 13 : 9783039431786
Total Pages : 154 pages
Book Rating : 4.4/5 (317 download)

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Book Synopsis The Fuzziness in Molecular, Supramolecular, and Systems Chemistry by : Pier Luigi Gentili

Download or read book The Fuzziness in Molecular, Supramolecular, and Systems Chemistry written by Pier Luigi Gentili and published by . This book was released on 2020-10 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fuzzy Logic is a good model for the human ability to compute words. It is based on the theory of fuzzy set. A fuzzy set is different from a classical set because it breaks the Law of the Excluded Middle. In fact, an item may belong to a fuzzy set and its complement at the same time and with the same or different degree of membership. The degree of membership of an item in a fuzzy set can be any real number included between 0 and 1. This property enables us to deal with all those statements of which truths are a matter of degree. Fuzzy logic plays a relevant role in the field of Artificial Intelligence because it enables decision-making in complex situations, where there are many intertwined variables involved. Traditionally, fuzzy logic is implemented through software on a computer or, even better, through analog electronic circuits. Recently, the idea of using molecules and chemical reactions to process fuzzy logic has been promoted. In fact, the molecular word is fuzzy in its essence. The overlapping of quantum states, on the one hand, and the conformational heterogeneity of large molecules, on the other, enable context-specific functions to emerge in response to changing environmental conditions. Moreover, analog input-output relationships, involving not only electrical but also other physical and chemical variables can be exploited to build fuzzy logic systems. The development of "fuzzy chemical systems" is tracing a new path in the field of artificial intelligence. This new path shows that artificially intelligent systems can be implemented not only through software and electronic circuits but also through solutions of properly chosen chemical compounds. The design of chemical artificial intelligent systems and chemical robots promises to have a significant impact on science, medicine, economy, security, and wellbeing. Therefore, it is my great pleasure to announce a Special Issue of Molecules entitled "The Fuzziness in Molecular, Supramolecular, and Systems Chemistry." All researchers who experience the Fuzziness of the molecular world or use Fuzzy logic to understand Chemical Complex Systems will be interested in this book.

Anticancer Agents

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ISBN 13 :
Total Pages : 388 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Anticancer Agents by : Iwao Ojima

Download or read book Anticancer Agents written by Iwao Ojima and published by . This book was released on 2001 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anticancer Agents: Frontiers in Cancer Chemotherapy describes cutting-edge approaches in the development of anticancer agents for chemotherapy.

Qualitative and Quantitative Analysis of Bioactive Natural Products 2018

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Publisher : MDPI
ISBN 13 : 3038977888
Total Pages : 374 pages
Book Rating : 4.0/5 (389 download)

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Book Synopsis Qualitative and Quantitative Analysis of Bioactive Natural Products 2018 by : Maria Carla Marcotullio

Download or read book Qualitative and Quantitative Analysis of Bioactive Natural Products 2018 written by Maria Carla Marcotullio and published by MDPI. This book was released on 2019-04-04 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout most of history, medicinal plants and their active metabolites have represented a valuable source of compounds used to prevent and to cure several diseases. Interest in natural compounds is still high as they represent a source of novel biologically/pharmacologically active compounds. Due to their high structural diversity and complexity, they are interesting structural scaffolds that can offer promising candidates for the study of new drugs, functional foods, and food additives. Plant extracts are a highly complex mixture of compounds and qualitative and quantitative analyses are necessary to ensure their quality. Furthermore, greener methods of extraction and analysis are needed today. This book is based on articles submitted for publication in the Special Issue entitled “Qualitative and Quantitative Analysis of Bioactive Natural Products” that collected original research and reviews on these topics.

Calorimetry and Thermal Analysis of Polymers

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Publisher : Hanser Gardner Publications
ISBN 13 : 9781569901267
Total Pages : 369 pages
Book Rating : 4.9/5 (12 download)

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Book Synopsis Calorimetry and Thermal Analysis of Polymers by : Vincent B. F. Mathot

Download or read book Calorimetry and Thermal Analysis of Polymers written by Vincent B. F. Mathot and published by Hanser Gardner Publications. This book was released on 1994-01 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Marine Natural Products Chemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 146840802X
Total Pages : 422 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Marine Natural Products Chemistry by : D. Faulkner

Download or read book Marine Natural Products Chemistry written by D. Faulkner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the lectures presented at the NATO sponsored conference on "Marine Natural Products" held in Jersey, Channel Islands, U. K., October 12-17, 1976. The intent of the organising committee was to encourage a dialogue between organic chemists who study the metabolites of marine organisms and biolo gists, ecologists, and pharmacologists who study the effects of these metabolites on other organisms. A feature of the conference was the three workshop sessions on chemotaxonomy, applications of marine natural products, and chemical communication. The papers presented at the conference contain a mixture of original research in marine natural products and reviews of some of the more important subjects. The biologists were asked to present papers which could initiate new directions for marine natural products research. Their contributions to the meeting were warmly received by the chemists in the audience. We hope that this volume contains not only past and present research but a suggestion of future research trends. The conference was first suggested by Dr. E. D. Goldberg. The organising committee, Drs. G. Blunden, D. J. Faulkner, W.

A Prologue to the Course

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Publisher :
ISBN 13 : 9780749297541
Total Pages : 114 pages
Book Rating : 4.2/5 (975 download)

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Book Synopsis A Prologue to the Course by :

Download or read book A Prologue to the Course written by and published by . This book was released on 2002 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: