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Author : R. H. Eaton
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (16 download)
Download or read book Isoenzyme Studies on Human Alkaline Phosphatases written by R. H. Eaton and published by . This book was released on 1969 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : R. Helen Eaton
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (111 download)
Download or read book Isoenzyme Studies on Human Alkaline Phosphatases written by R. Helen Eaton and published by . This book was released on 1969 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Torgny Stigbrand
Publisher :
ISBN 13 :
Total Pages : 400 pages
Book Rating : 4.3/5 (91 download)
Download or read book Human Alkaline Phosphatases written by Torgny Stigbrand and published by . This book was released on 1984 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kazuyuki Hirano
Publisher :
ISBN 13 : 9789171745231
Total Pages : 35 pages
Book Rating : 4.7/5 (452 download)
Download or read book Human Alkaline Phosphatases written by Kazuyuki Hirano and published by . This book was released on 1990 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : José Luis Millan
Publisher : John Wiley & Sons
ISBN 13 : 3527607471
Total Pages : 337 pages
Book Rating : 4.5/5 (276 download)
Download or read book Mammalian Alkaline Phosphatases written by José Luis Millan and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers: * The structure, regulation and expression of the AP genes * The three-dimensional structure of APs and mutagenesis work that further defined the structural/functional domains of the isozymes * The phenotypic abnormalities of the different AP knockout mice * Our current understanding of the in vivo role of the AP isozymes. The book also describes the possible use of APs as therapeutic agents and therapeutic targets and the many uses of these enzymes in clinical medicine and in biotechnology.
Author :
Publisher :
ISBN 13 :
Total Pages : 530 pages
Book Rating : 4.:/5 (94 download)
Download or read book Analysis of Isoenzymes and Isoforms of Human Alkaline Phosphatase, Hexosaminidase and Transferrin by Micro-column Chromatography written by and published by . This book was released on 1994 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Robert B. McComb
Publisher : Springer Science & Business Media
ISBN 13 : 1461329701
Total Pages : 998 pages
Book Rating : 4.4/5 (613 download)
Download or read book Alkaline Phosphatase written by Robert B. McComb and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 998 pages. Available in PDF, EPUB and Kindle. Book excerpt: There can be no doubt that alkaline phosphatase is one of the most extensively in vestigated of all enzymes. This has resulted from the ubiquity of its distribution, and from the ease and sensitivity with which its activity can be measured. Unfortunately, these wide-ranging but often superficial experimental studies have been followed up by intensive and systematic investigations in only a few limited areas of the biochemistry and chemical pathology of alkaline phosphatase. The result has been the accumulation of a scientific literature of intimidating proportions, and the inevitable rediscovery of already known facts about the enzyme. Scientists are taught early in their careers that, in the words of Sir John Herschel, "Hasty generalization is the bane of science. " Nevertheless, moments arrive in all spheres of scientific activity when generalization becomes essential, to codify and to select from the mass of data already accumulated, and to provide starting points for new developments and new lines of investigation. This is especially true in a field such as alkaline phosphatase research, in which very real dangers exist that the seeds of fundamental understanding will be lost amidst an unexamined harvest of empirical observations. The history of the study of alkaline phosphatase provides several instances when valuable generalizations have emerged. Occasionally, the conclusions drawn on the basis of available evidence were wrong; more frequently, they have stood the test of further experimentation, and always, they have provided new insights into the nature and proper ties of this enzyme.
Author : Albert Latner
Publisher : Elsevier
ISBN 13 : 0323156940
Total Pages : 301 pages
Book Rating : 4.3/5 (231 download)
Download or read book Isoenzymes In Biology and Medicine written by Albert Latner and published by Elsevier. This book was released on 2012-12-02 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Isoenzymes in Biology and Medicine attempts to give an account of the study of isoenzymes in relation to humans, animals, insects, higher plants, fungi, protozoa, algae, and bacteria. This book discusses the chemical structure, physiological aspects, metabolic role, and function of isoenzyme observations in genetic, ontogenic, and phylogenic studies. A detailed account of the use of isoenzyme in the diagnosis and pathogenesis of disease and control of therapy is also provided. This text likewise considers the isoenzymes of the oxidoreductases, transferases, and hydrolases, including its relation to clinical medicine. This publication is intended for biochemists, biologists, clinical biochemists and physicians.
Author : Charlotte Anne Chilcot
Publisher :
ISBN 13 :
Total Pages : 426 pages
Book Rating : 4.:/5 (926 download)
Download or read book Studies on the Genetically Determined Differences of Human Placental Alkaline Phosphatase Isoenzymes written by Charlotte Anne Chilcot and published by . This book was released on 1970 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : José Luis Millán
Publisher : Humana
ISBN 13 : 9781493960316
Total Pages : 0 pages
Book Rating : 4.9/5 (63 download)
Download or read book Phosphatase Modulators written by José Luis Millán and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Driving further the research on mammalian alkaline phosphatase structure and function, Phosphatase Modulators collects expert contributions into one “how to” manual for basic scientists interested in initiating a drug discovery effort. While this book contains the traditional method chapters and some typical reviews on the structure and known functions of phosphatases, other contributions are meant to discuss approaches and alternatives useful in making “go/no-go” decisions in high throughput screening (HTS) and lead optimization campaigns. Many chapters focus on tissue-nonspecific alkaline phosphatase (TNAP) as well as protein phosphatases. Written for the highly successful Methods in Molecular Biology series, chapters in this volume include the kind of detail and key implementation advice that promotes reproducible results. Step-by-step and practical, Phosphatase Modulators offers a path to understanding many of the facets and complexities associated with undertaking a drug discovery effort and will serve as a roadmap to initiating those efforts.
Author : D. W. Moss
Publisher : Springer Science & Business Media
ISBN 13 : 9400958862
Total Pages : 266 pages
Book Rating : 4.4/5 (9 download)
Download or read book Isoenzymes written by D. W. Moss and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increased interest in multiple forms of enzymes that began with the application of new methods of fractionation to preparations of enzymes and other proteins some 25 years ago led quickly to an appreciation that the existence of enzymes in multiple forms, or isoenzymes, is a general phenomenon. The results of pioneering studies and those which followed in the early years of isoenzyme research consisted, not surprisingly, mainly of descriptions of the existence and characteristics of hetero geneity in various enzyme systems. Summaries of these results were provided in books such as J . H. Wilkinson's I soenzymes, the first edition of which appeared in 1965. Some clearer ideas of the nature of the phenomena had become apparent by the time that the second edition of Isoenzymes was called for in 1970, and a limited use of the word isoenzymes itself, to describe only certain of the various categories of enzyme multiplicity then recognized, was already being proposed. Nevertheless, a largely enzyme-by-enzyme oTganization of the contents of the book was still appropriate. Considerable advances, both experimental and conceptual, were made in isoenzyme research in the 1970s, and in 1977 Professor Wilkinson suggested to the present author that these should be taken into account in a joint revision of Isoenzymes. Professor Wilkinson's untimely death put. an end to this project and the present book is therefore the work of a single author.
Author : Emmanuelle Di-Tomaso
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (112 download)
Download or read book Analysis of Isoenzymes and Isoforms of Human Alkaline Phosphatase, Hexosaminidase and Transferrin by Micro-column Chromatography written by Emmanuelle Di-Tomaso and published by . This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Shulamit Matiash-Epstein
Publisher :
ISBN 13 :
Total Pages : 152 pages
Book Rating : 4.:/5 (884 download)
Download or read book A Combined Human and Animal Study of Alkaline Phosphatase Isoenzymes in Lymphatic and Myeloid Leukemia written by Shulamit Matiash-Epstein and published by . This book was released on 1981 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : John C. Griffiths
Publisher :
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.3/5 (91 download)
Download or read book Clinical Enzymology written by John C. Griffiths and published by . This book was released on 1979 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Amy Priscilla Block
Publisher :
ISBN 13 :
Total Pages : 318 pages
Book Rating : 4.:/5 (29 download)
Download or read book Studies on Intestinal Alkaline Phosphatase in Humans and in Rats written by Amy Priscilla Block and published by . This book was released on 1979 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Nikolaos Labrou
Publisher : Springer Nature
ISBN 13 : 981137709X
Total Pages : 388 pages
Book Rating : 4.8/5 (113 download)
Download or read book Therapeutic Enzymes: Function and Clinical Implications written by Nikolaos Labrou and published by Springer Nature. This book was released on 2019-09-03 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic enzymes exhibit fascinating features and opportunities, and represent a significant and promising subcategory of modern biopharmaceuticals for the treatment of several severe diseases. Research and drug developments efforts and the advancements in biotechnology over the past twenty years have greatly assisted the introduction of efficient and safe enzyme-based therapies for a range of both rare and common disorders. The introduction and regulatory approval of twenty different recombinant enzymes has enabled effective enzyme-replacement therapy. This volume aims to overview these therapeutic enzymes, focusing in particular on more recently approved enzymes produced by recombinant DNA technology. This volume is composed of four sections. Section 1 provides an overview of the production process and biochemical characterization of therapeutic enzymes, while Section 2 focuses upon the engineering strategies and delivery methods of therapeutic enzymes. Section 3 highlights the clinical applications of approved therapeutic enzymes, including aspects on their structure, indications and mechanisms of action. Together with information on these mechanisms, safety and immunogenicity issues and various adverse events of the recombinant enzymes used for therapy are discussed. Section 4, provides discussion on the prospective and future developments of new therapeutic enzymes. This book is aimed at academics, researchers and students undertaking advanced undergraduate/postgraduate programs in the biopharmaceutical/biotechnology area who wish to gain a comprehensive understanding of enzyme-based therapeutic molecules.
Author : Inga Hägerstrand
Publisher :
ISBN 13 :
Total Pages : 23 pages
Book Rating : 4.:/5 (185 download)
Download or read book The Alkaline Phosphatase Isoenzyme of Human Bile Canaliculi written by Inga Hägerstrand and published by . This book was released on 1976 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt:
