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Investigating Protein Surfaces And Protein Interactions Using The Element Coded Affinity Tags Ecat
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Book Synopsis Investigating Protein Surfaces and Protein Interactions Using the Element-coded Affinity Tags (ECAT) by : Susan Lee
Download or read book Investigating Protein Surfaces and Protein Interactions Using the Element-coded Affinity Tags (ECAT) written by Susan Lee and published by . This book was released on 2006 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Protein Interactions by : M.Michael Gromiha
Download or read book Protein Interactions written by M.Michael Gromiha and published by World Scientific Publishing Company. This book was released on 2020-03-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interactions of proteins with other molecules are important in many cellular activities. Investigations have been carried out to understand the recognition mechanism, identify the binding sites, analyze the the binding affinity of complexes, and study the influence of mutations on diseases. Protein interactions are also crucial in structure-based drug design. This book covers computational analysis of protein-protein, protein-nucleic acid and protein-ligand interactions and their applications. It provides up-to-date information and the latest developments from experts in the field, using illustrations to explain the key concepts and applications. This volume can serve as a single source on comparative studies of proteins interacting with proteins/DNAs/RNAs/carbohydrates and small molecules.
Book Synopsis Protein Affinity Tags by : Richard J. Giannone
Download or read book Protein Affinity Tags written by Richard J. Giannone and published by Humana. This book was released on 2014-06-19 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Affinity Tags: Methods and Protocols provides researchers with the necessary information, tools, and strategy required for proper inquiry into a given protein’s function and structure. Today’s researchers can easily alter the amino acid sequence of any given protein, a powerful technology allowing for the precise engineering of specific proteins. Protein affinity tagging employs the use of known protein binding interactions in order to “fish out” a protein-of-interest or, with more advanced tags, a protein complex. This technology paired with recent advancements in DNA sequencing technology promises a future that is awash with novel genomic information – information that will not only expand our knowledge of the processes that govern life, but also fuel innovation that will undoubtedly conquer many of today’s most salient health and environmental challenges. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Protein Affinity Tags: Methods and Protocols will be an invaluable resource to those seeking to employ protein affinity tags to study their biological system of interest.
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2006 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Peptide Therapeutics by : Ved Srivastava
Download or read book Peptide Therapeutics written by Ved Srivastava and published by Royal Society of Chemistry. This book was released on 2019-08-28 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptide therapy has become a key strategy in innovative drug development, however, one of the potential barriers for the development of novel peptide drugs in the clinic is their deficiencies in clearly defined chemistry, manufacturing and controls (CMC) strategy from clinical development to commercialization. CMC can often become a rate-limiting step due to lack of knowledge and lack of a formal policy or guidelines on CMC for peptide-based drugs. Regulators use a risk-based approach, reviewing applications on a case-by-case basis. Peptide Therapeutics: Strategy and Tactics for Chemistry, Manufacturing, and Controls covers efficient manufacturing of peptide drug substances, a review of the process for submitting applications to the regulatory authority for drug approval, a holistic approach for quality attributes and quality control from a regulatory perspective, emerging analytical tools for the characterisation of impurities, and the assessment of stability. This book is an essential reference work for students and researchers, in both academia and industry, with an interest in learning about CMC, and facilitating development and manufacture of peptide-based drugs.
Book Synopsis The Photomultiplier Handbook by : A. G. Wright
Download or read book The Photomultiplier Handbook written by A. G. Wright and published by Oxford University Press. This book was released on 2017 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Photomultipliers are extremely sensitive light detectors with the capability to detect single photons. In multiplying the charge produced by incident light by up to 100 million times, these devices are essential to a wide range of applications, from medical instrumentation to astronomical observations. This complete and authoritative guide will provide...a deeper understanding of the operating principles of these devices." -- Publisher's description, back cover.
Book Synopsis Laboratory Techniques in Thrombosis — a Manual by : J. Jespersen
Download or read book Laboratory Techniques in Thrombosis — a Manual written by J. Jespersen and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this manual appeared in 1992 and was entitled ECAT Assay Procedures. It was the result of a unique cooperation between experts brought together by the European Concerted Action on Thrombosis and Disabilities (ECAT). The Concerted Action was at that time under the auspices of the Commission of the European Union. The second edition, like the first edition, deals with diagnostic tests within the field of thrombosis. However, the second edition has a broader scope because it is no longer limited by the frontiers of ECAT. Experts allover the world, in and outside ECAT, have contributed to this edition. The editors are very grateful for their contributions. The need for a new edition is obvious. Since 1992 new assays have been introduced for research, diagnosis, and therapy of thrombosis; for other assays improvements have been suggested, while a few others became redundant. The editors waived the radioimmunoassays of ~-thrombog1obulin and platelet factor 4 due to the fact that the kits required for these assays are rarely, or no longer, available. Also the PAI-1 activity assay was waived as it is liable to many inconsistencies and to large variations. A list of names and addresses of manufacturers marketing the kits and reagents has been compiled, together with a list of the recommended nomenclature of quantities in thrombosis and haemostasis, in order to facilitate the use of the updated version. These lists have been carefully compiled by Johannes J. Sidelmann, PhD, Department of Clinical Biochemistry in Esbjerg, Denmark.
Book Synopsis Redox Proteomics by : Isabella Dalle-Donne
Download or read book Redox Proteomics written by Isabella Dalle-Donne and published by John Wiley & Sons. This book was released on 2006-08-11 with total page 978 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methodology and applications of redox proteomics The relatively new and rapidly changing field of redox proteomics has the potential to revolutionize how we diagnose disease, assess risks, determine prognoses, and target therapeutic strategies for people with inflammatory and aging-associated diseases. This collection brings together, in one comprehensive volume, a broad array of information and insights into normal and altered physiology, molecular mechanisms of disease states, and new applications of the rapidly evolving techniques of proteomics. Written by some of the finest investigators in this area, Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases examines the key topics of redox proteomics and redox control of cellular function, including: * The role of oxidized proteins in various disorders * Pioneering studies on the development of redox proteomics * Analytical methodologies for identification and structural characterization of proteins affected by oxidative/nitrosative modifications * The response and regulation of protein oxidation in different cell types * The pathological implications of protein oxidation for conditions, including asthma, cardiovascular disease, diabetes, preeclampsia, and Alzheimer's disease Distinguished by its in-depth discussions, balanced methodological approach, and emphasis on medical applications and diagnosis development, Redox Proteomics is a rich resource for all professionals with an interest in proteomics, cellular physiology and its alterations in disease states, and related fields.
Author :Shankar Vallabhajosula Publisher :Springer Science & Business Media ISBN 13 :3540767355 Total Pages :379 pages Book Rating :4.5/5 (47 download)
Book Synopsis Molecular Imaging by : Shankar Vallabhajosula
Download or read book Molecular Imaging written by Shankar Vallabhajosula and published by Springer Science & Business Media. This book was released on 2009-07-13 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.
Book Synopsis Dorland's Dictionary of Medical Acronyms and Abbreviations by : Dorland
Download or read book Dorland's Dictionary of Medical Acronyms and Abbreviations written by Dorland and published by Elsevier Health Sciences. This book was released on 2015-07-24 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical acronyms and abbreviations offer convenience, but those countless shortcuts can often be confusing. Now a part of the popular Dorland's suite of products, this reference features thousands of terms from across various medical specialties. Its alphabetical arrangement makes for quick reference, and expanded coverage of symbols ensures they are easier to find. Effective communication plays an important role in all medical settings, so turn to this trusted volume for nearly any medical abbreviation you might encounter. - Symbols section makes it easier to locate unusual or seldom-used symbols. - Convenient alphabetical format allows you to find the entry you need more intuitively. - More than 90,000 entries and definitions. - Many new and updated entries including terminology in expanding specialties, such as Nursing; Physical, Occupational, and Speech Therapies; Transcription and Coding; Computer and Technical Fields. - New section on abbreviations to avoid, including Joint Commission abbreviations that are not to be used. - Incorporates updates suggested by the Institute for Safe Medication Practices (ISMP).
Download or read book Gaba written by Chikako Tanaka and published by Springer Science & Business Media. This book was released on 1996 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highlighting the current developments and future directions in GABA research, the ambitious aim of this topical volume is to cover GABA from the molecular mechanisms of its transmission to new targets for pharmaceutical research. Distinguished scientists at the forefront of GABA research were invited to contribute reviews on glutamate decarboxylase and autoimmunity, molecular structure and functional regulation of GABA transporters, transmitter release and GABA receptor regulation, GABA receptor subtypes and functional regulation, and GABA receptor ligands and their therapeutic application. Describing the latest advances in what has become a rapidly-evolving field, this volume will prove immensely valuable to neuroscientists, pharmacologists, biochemists, and physiologists working in the field of GABA research.
Book Synopsis Targeted Molecular Imaging in Oncology by : E. Edmund Kim
Download or read book Targeted Molecular Imaging in Oncology written by E. Edmund Kim and published by Springer Science & Business Media. This book was released on 2001 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer cells dedifferentiate with repect to cell function; their vascularity is more leaky, but perfusion is heterogenerously reduced, and interstitial fluid pressure is high, severely retarding delivery of agents from the blood. Targeted imaging is designed to produce a detectable difference between tissue that is visualized with single photon and positron emission tomography, magnetic resonance imaging, computed tomography, or ultrasonography. This book uniquely reports strategies for the application of molecular targeted imaging agents such as antibodies, peptides, receptors and contrast agents in the biologic grading of tumors, differential diagnosis of tumors, prediction of therapeutic response and monitoring tumor response to treatment. This book also describes updated information about the imaging of tumor angiogenesis, hypoxia, apoptosis and gene delivery as well as expression in the understanding and utility of tumor molecular biology for better cancer management.
Book Synopsis Radiative Decay Engineering by : Chris D. Geddes
Download or read book Radiative Decay Engineering written by Chris D. Geddes and published by Springer Science & Business Media. This book was released on 2007-12-11 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: During recent years our enthusiasm for this field has continually increased. This book presents expert contributions describing the fundamental principles for the widespread use of radiative decay engineering in the biological sciences and nanotechnology.
Book Synopsis Challenges in Delivery of Therapeutic Genomics and Proteomics by : Ambikanandan Misra
Download or read book Challenges in Delivery of Therapeutic Genomics and Proteomics written by Ambikanandan Misra and published by Elsevier. This book was released on 2010-09-09 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: Delivery of therapeutic proteomics and genomics represent an important area of drug delivery research. Genomics and proteomics approaches could be used to direct drug development processes by unearthing pathways involved in disease pathogenesis where intervention may be most successful. This book describes the basics of genomics and proteomics and highlights the various chemical, physical and biological approaches to protein and gene delivery. - Covers a diverse array of topics from basic sciences to therapeutic applications of proteomics and genomics delivery - Of interest to researchers in both academia and industry - Highlights what's currently known and where further research is needed
Book Synopsis Prevention and Treatment of Atherosclerosis by : Arnold von Eckardstein
Download or read book Prevention and Treatment of Atherosclerosis written by Arnold von Eckardstein and published by Springer Nature. This book was released on 2022 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book is supported by the European Atherosclerosis Society Association (EAS). This follow-up edition of the well-received Handbook volume 'Atherosclerosis: Diet and Drugs' reflects the state-of-the-art and most recent developments in atherosclerosis research. Outstanding international experts give a comprehensive overview of the field covering topics, such as improving the treatment focusing on established targets, novel drug developments addressing pre-defined targets, hypothesis-based and hypothesis-free approaches to unravel novel targets.
Book Synopsis NMR of Paramagnetic Molecules by : Ivano Bertini
Download or read book NMR of Paramagnetic Molecules written by Ivano Bertini and published by Elsevier. This book was released on 2016-09-15 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: NMR of Paramagnetic Molecules: Applications to Metallobiomolecules and Models, Second Edition is a self-contained, comprehensive reference for chemists, physicists, and life scientists whose research involves analyzing paramagnetic compounds. Since the previous edition of this book was published, there have been many advancements in the field of paramagnetic NMR spectroscopy. This completely updated and expanded edition contains the latest fundamental theory and methods for mastery of this analytical technique. Users will learn how to interpret the NMR spectra of paramagnetic molecules, improve experimental techniques, and strengthen their understanding of the underlying theory and applications. - Reflects all advances in the field in a completely updated new edition - Presents new material on self-orientation residual dipolar couplings, solid state NMR, dynamic nuclear polarization, and paramagnetic restraints for structure calculations - Includes information relevant to paramagnetic molecules, metallobiomolecules, paramagnetic compounds, and paramagnetic NMR spectroscopy - Presents specific examples of paramagnetic inorganic species and experimental techniques for structure characterization
Book Synopsis Proteomic Applications in Biology by : Joshua Heazlewood
Download or read book Proteomic Applications in Biology written by Joshua Heazlewood and published by BoD – Books on Demand. This book was released on 2012-01-18 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has seen the field of proteomics expand from a highly technical endeavor to a widely utilized technique. The objective of this book is to highlight the ways in which proteomics is currently being employed to address issues in the biological sciences. Although there have been significant advances in techniques involving the utilization of proteomics in biology, fundamental approaches involving basic sample visualization and protein identification still represent the principle techniques used by the vast majority of researchers to solve problems in biology. The work presented in this book extends from overviews of proteomics in specific biological subject areas to novel studies that have employed a proteomics-based approach. Collectively they demonstrate the power of established and developing proteomic techniques to characterize complex biological systems.
