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Investigating Biological Systems Using Modeling
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Book Synopsis Investigating Biological Systems Using Modeling by : Meryl E. Wastney
Download or read book Investigating Biological Systems Using Modeling written by Meryl E. Wastney and published by Academic Press. This book was released on 1999 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Investigating Biological Systems Using Modeling describes how to apply software to analyze and interpret data from biological systems. It is written for students and investigators in lay person's terms, and will be a useful reference book and textbook on mathematical modeling in the design and interpretation of kinetic studies of biological systems. It describes the mathematical techniques of modeling and kinetic theory, and focuses on practical examples of analyzing data. The book also uses examples from the fields of physiology, biochemistry, nutrition, agriculture, pharmacology, and medicine. Contains practical descriptions of how to analyze kinetic data Provides examples of how to develop and use models Describes several software packages including SAAM/CONSAM Includes software with working models
Book Synopsis Modeling Dynamic Biological Systems by : Bruce Hannon
Download or read book Modeling Dynamic Biological Systems written by Bruce Hannon and published by Springer. This book was released on 2014-07-05 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many biologists and ecologists have developed models that find widespread use in theoretical investigations and in applications to organism behavior, disease control, population and metapopulation theory, ecosystem dynamics, and environmental management. This book captures and extends the process of model development by concentrating on the dynamic aspects of these processes and by providing the tools such that virtually anyone with basic knowledge in the Life Sciences can develop meaningful dynamic models. Examples of the systems modeled in the book range from models of cell development, the beating heart, the growth and spread of insects, spatial competition and extinction, to the spread and control of epidemics, including the conditions for the development of chaos. Key features: - easy-to-learn and easy-to-use software - examples from many subdisciplines of biology, covering models of cells, organisms, populations, and metapopulations - no prior computer or programming experience required Key benefits: - learn how to develop modeling skills and system thinking on your own rather than use models developed by others - be able to easily run models under alternative assumptions and investigate the implications of these assumptions for the dynamics of the biological system being modeled - develop skills to assess the dynamics of biological systems
Book Synopsis Mathematical Modeling in Systems Biology by : Brian P. Ingalls
Download or read book Mathematical Modeling in Systems Biology written by Brian P. Ingalls and published by MIT Press. This book was released on 2022-06-07 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.
Book Synopsis Investigating Biological Systems Using Modeling by : Meryl E. Wastney
Download or read book Investigating Biological Systems Using Modeling written by Meryl E. Wastney and published by Academic Press. This book was released on 2012-12-02 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Investigating Biological Systems Using Modeling describes how to apply software to analyze and interpret data from biological systems. It is written for students and investigators in lay person's terms, and will be a useful reference book and textbook on mathematical modeling in the design and interpretation of kinetic studies of biological systems. It describes the mathematical techniques of modeling and kinetic theory, and focuses on practical examples of analyzing data. The book also uses examples from the fields of physiology, biochemistry, nutrition, agriculture, pharmacology, and medicine. Contains practical descriptions of how to analyze kinetic data Provides examples of how to develop and use models Describes several software packages including SAAM/CONSAM Includes software with working models
Author :Abdelghani Bellouquid Publisher :Springer Science & Business Media ISBN 13 :0817643958 Total Pages :194 pages Book Rating :4.8/5 (176 download)
Book Synopsis Mathematical Modeling of Complex Biological Systems by : Abdelghani Bellouquid
Download or read book Mathematical Modeling of Complex Biological Systems written by Abdelghani Bellouquid and published by Springer Science & Business Media. This book was released on 2006-08-17 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the evolution of several socio-biological systems using mathematical kinetic theory. Specifically, it deals with modeling and simulations of biological systems whose dynamics follow the rules of mechanics as well as rules governed by their own ability to organize movement and biological functions. It proposes a new biological model focused on the analysis of competition between cells of an aggressive host and cells of a corresponding immune system. Proposed models are related to the generalized Boltzmann equation. The book may be used for advanced graduate courses and seminars in biological systems modeling.
Book Synopsis Modeling Dynamic Biological Systems by : Bruce Hannon
Download or read book Modeling Dynamic Biological Systems written by Bruce Hannon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Models help us understand the dynamics of real-world processes by using the computer to mimic the actual forces that are known or assumed to result in a system's behavior. This book does not require a substantial background in mathematics or computer science.
Book Synopsis Computational Modeling of Biological Systems by : Nikolay V Dokholyan
Download or read book Computational Modeling of Biological Systems written by Nikolay V Dokholyan and published by Springer Science & Business Media. This book was released on 2012-02-12 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational modeling is emerging as a powerful new approach to study and manipulate biological systems. Multiple methods have been developed to model, visualize, and rationally alter systems at various length scales, starting from molecular modeling and design at atomic resolution to cellular pathways modeling and analysis. Higher time and length scale processes, such as molecular evolution, have also greatly benefited from new breeds of computational approaches. This book provides an overview of the established computational methods used for modeling biologically and medically relevant systems.
Download or read book Modeling Life written by Alan Garfinkel and published by Springer. This book was released on 2017-09-06 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?
Download or read book Models of Life written by Kim Sneppen and published by Cambridge University Press. This book was released on 2014-10-02 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of current models of biological systems, reflecting the major advances that have been made over the past decade.
Author :Abdelghani Bellouquid Publisher :Springer Science & Business Media ISBN 13 :0817645039 Total Pages :194 pages Book Rating :4.8/5 (176 download)
Book Synopsis Mathematical Modeling of Complex Biological Systems by : Abdelghani Bellouquid
Download or read book Mathematical Modeling of Complex Biological Systems written by Abdelghani Bellouquid and published by Springer Science & Business Media. This book was released on 2007-10-10 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the evolution of several socio-biological systems using mathematical kinetic theory. Specifically, it deals with modeling and simulations of biological systems whose dynamics follow the rules of mechanics as well as rules governed by their own ability to organize movement and biological functions. It proposes a new biological model focused on the analysis of competition between cells of an aggressive host and cells of a corresponding immune system. Proposed models are related to the generalized Boltzmann equation. The book may be used for advanced graduate courses and seminars in biological systems modeling.
Book Synopsis Computer Modeling of Complex Biological Systems by : S. Sitharama Iyengar
Download or read book Computer Modeling of Complex Biological Systems written by S. Sitharama Iyengar and published by CRC Press. This book was released on 1984-01-13 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: :Computer modeling of biological systems, a process of building new sets of conceptualizations, theories, and implementations is cov-ered in depth. The emphasis is on how computer modeling encom-passes three distinct areas of science (computer science, biology, and medicine) for building a framework for investigating the behavior of a complex biological system. Simulation and modeling are dis-cussed because these two factors provide the methodology for the design, development, experimentation, analysis, and evaluation of a experiment under study. Because of their high degree of modular-ity and collective complexity, computer systems such as analog, digital, or hybrid are reviewed. This presentation of computer mod-eling of biological systems delves into the study of data represen-tation (or data structures) and their transformation into an empirical model via a software program.
Book Synopsis Biological Modeling and Simulation by : Russell Schwartz
Download or read book Biological Modeling and Simulation written by Russell Schwartz and published by MIT Press. This book was released on 2008-07-25 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practice-oriented survey of techniques for computational modeling and simulation suitable for a broad range of biological problems. There are many excellent computational biology resources now available for learning about methods that have been developed to address specific biological systems, but comparatively little attention has been paid to training aspiring computational biologists to handle new and unanticipated problems. This text is intended to fill that gap by teaching students how to reason about developing formal mathematical models of biological systems that are amenable to computational analysis. It collects in one place a selection of broadly useful models, algorithms, and theoretical analysis tools normally found scattered among many other disciplines. It thereby gives the aspiring student a bag of tricks that will serve him or her well in modeling problems drawn from numerous subfields of biology. These techniques are taught from the perspective of what the practitioner needs to know to use them effectively, supplemented with references for further reading on more advanced use of each method covered. The text, which grew out of a class taught at Carnegie Mellon University, covers models for optimization, simulation and sampling, and parameter tuning. These topics provide a general framework for learning how to formulate mathematical models of biological systems, what techniques are available to work with these models, and how to fit the models to particular systems. Their application is illustrated by many examples drawn from a variety of biological disciplines and several extended case studies that show how the methods described have been applied to real problems in biology.
Book Synopsis Mathematical Modelling of Dynamic Biological Systems by : Ludwik Finkelstein
Download or read book Mathematical Modelling of Dynamic Biological Systems written by Ludwik Finkelstein and published by John Wiley & Sons. This book was released on 1985-05-08 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume introduces readers to the methodology of dynamic systems analysis, using mathematical modelling techniques as an aid to understanding biological phenomena. It creates an ability to appreciate current medical and biological literature, in which mathematical models are being used with increasing frequency, and provides an introduction to the more advanced techniques of systems science. Mathematical concepts are illustrated by reference to frequent biological examples. By the use of case studies drawn from physiology, the various levels of mathematical modelling which can be adopted are presented.
Book Synopsis A Biologist's Guide to Mathematical Modeling in Ecology and Evolution by : Sarah P. Otto
Download or read book A Biologist's Guide to Mathematical Modeling in Ecology and Evolution written by Sarah P. Otto and published by Princeton University Press. This book was released on 2011-09-19 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirty years ago, biologists could get by with a rudimentary grasp of mathematics and modeling. Not so today. In seeking to answer fundamental questions about how biological systems function and change over time, the modern biologist is as likely to rely on sophisticated mathematical and computer-based models as traditional fieldwork. In this book, Sarah Otto and Troy Day provide biology students with the tools necessary to both interpret models and to build their own. The book starts at an elementary level of mathematical modeling, assuming that the reader has had high school mathematics and first-year calculus. Otto and Day then gradually build in depth and complexity, from classic models in ecology and evolution to more intricate class-structured and probabilistic models. The authors provide primers with instructive exercises to introduce readers to the more advanced subjects of linear algebra and probability theory. Through examples, they describe how models have been used to understand such topics as the spread of HIV, chaos, the age structure of a country, speciation, and extinction. Ecologists and evolutionary biologists today need enough mathematical training to be able to assess the power and limits of biological models and to develop theories and models themselves. This innovative book will be an indispensable guide to the world of mathematical models for the next generation of biologists. A how-to guide for developing new mathematical models in biology Provides step-by-step recipes for constructing and analyzing models Interesting biological applications Explores classical models in ecology and evolution Questions at the end of every chapter Primers cover important mathematical topics Exercises with answers Appendixes summarize useful rules Labs and advanced material available
Book Synopsis Structured Biological Modelling by : Michael Kraus
Download or read book Structured Biological Modelling written by Michael Kraus and published by CRC Press. This book was released on 1995-07-31 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structured Biological Modelling presents a straightforward introduction for computer-aided analysis, mathematical modelling, and simulation of cell biological systems. This unique guide brings together the physiological, structural, molecular biological, and theoretical aspects of the signal transduction network that regulates growth and proliferation in normal and tumor cells. It provides comprehensive survey of functional and theoretical features of intracellular signal processing and introduces the concept of cellular self-organization. Exemplified by oscillatory calcium waves, strategies for the design of computer experiments are presented that can assist or even substitute for time-consuming biological experiments. The presented minimal model for proliferation-associated signal transduction clearly shows the alterations of the cellular signal network involved in neoplastic growth. This book will be useful to cell and molecular biologists, oncologists, physiologists, theoretical biologists, computer scientists, and all other researchers and students studying functional aspects of cellular signaling.
Book Synopsis Stochastic Models in Biology by : Narendra S. Goel
Download or read book Stochastic Models in Biology written by Narendra S. Goel and published by Elsevier. This book was released on 2016-01-26 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stochastic Models in Biology describes the usefulness of the theory of stochastic process in studying biological phenomena. The book describes analysis of biological systems and experiments though probabilistic models rather than deterministic methods. The text reviews the mathematical analyses for modeling different biological systems such as the random processes continuous in time and discrete in state space. The book also discusses population growth and extinction through Malthus' law and the work of MacArthur and Wilson. The text then explains the dynamics of a population of interacting species. The book also addresses population genetics under systematic evolutionary pressures known as deterministic equations and genetic changes in a finite population known as stochastic equations. The text then turns to stochastic modeling of biological systems at the molecular level, particularly the kinetics of biochemical reactions. The book also presents various useful equations such as the differential equation for generating functions for birth and death processes. The text can prove valuable for biochemists, cellular biologists, and researchers in the medical and chemical field who are tasked to perform data analysis.
