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Introduction To Novel Motor Neuron Disease
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Book Synopsis Molecular and Cellular Therapies for Motor Neuron Diseases by : Nicholas M Boulis
Download or read book Molecular and Cellular Therapies for Motor Neuron Diseases written by Nicholas M Boulis and published by Academic Press. This book was released on 2017-01-18 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians. Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials. Provides an overview of gene and cell therapies for amyotrophic lateral sclerosis (ALS) and other motor neuron diseases Edited by a leading Neurosurgeon and two research scientists to promote synthesis between basic neuroscience and clinical relevance Presents a great resource for researchers and practitioners in neuroscience, neurology, and gene and cell therapy
Book Synopsis Introduction to Novel Motor Neuron Disease by : Humberto Foyaca Sibat
Download or read book Introduction to Novel Motor Neuron Disease written by Humberto Foyaca Sibat and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motor neuron disease (MND) is a progressive and fatal neuromuscular disease; the most common and severe form of MND presentation is amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig,Äôs disease. The majority of ALS patients die within 2,Äì5¬†years of receiving a diagnosis. Familial ALS is a hereditary form of the disease and accounts for 5,Äì10% of cases, whereas the remaining cases have no clearly defined etiology. ALS affects persons of all ethnicities and races; currently, no curative treatment for ALS is available worldwide. ALS is also the major adult-onset MND and is clinically, pathologically, and genetically associated with fronto-temporal dementia in some cases, which is the second cause of dementia in elderly people. However, MND does not affect sphincter, sexual function, or eye movements. MND is the most common degenerative disorder affecting the upper and lower motor neurons at the same time. Most of the patients presenting MND in our series complained of muscle weakness, muscle wasting, fasciculation, and spasticity plus lower cranial nerve disturbances. According to our bibliographic studies, apart from nusinersen, it seems to be that riluzole and edaravone also improve motor neuron function by acting on SK channels.
Book Synopsis Motor Neuron Disease in Adults by : Mark B. Bromberg
Download or read book Motor Neuron Disease in Adults written by Mark B. Bromberg and published by Contemporary Neurology. This book was released on 2014-10-28 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Motor Neuron Disease in Adults' reviews new information from 1998 as it applies to all aspects of motor neuron disease. Articles included use evidence-based methods to ensure that the new information is solid and advances the topic. The book can be used by anyone who provides any type of care to ALS patients.
Book Synopsis Motor Neuron Disease by : P.N. Leigh
Download or read book Motor Neuron Disease written by P.N. Leigh and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is the first book to provide a comprehensive overview of the clinical, pathological, and research aspects of motor neuron disease (MND). The text contains all essential features of the anatomy, physiology, pharmacology and toxicology of the motor system, a full description of MND and its variants, as well as historical developments and a review of the current concepts and controversies. This book comes at a time of increasing interest in neurodegenerative disorders and MND in particular. It will prove a key reference book with an integrated overview of the field, and will be indispensable to practicing neurologists, researchers, and all those with an interest in MND.
Book Synopsis Novel Aspects on Motor Neuron Disease by : Humberto Foyaca Sibat
Download or read book Novel Aspects on Motor Neuron Disease written by Humberto Foyaca Sibat and published by BoD – Books on Demand. This book was released on 2020-05-20 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dedicated to our readers, we include novel information (not reported in IntechOpen’s books before) about new contributions of aberrant astrocytes to MND damage and death in the SOD1G93A rat experimental model of ALS; novel genetic studies on ALS; an update of the structural and functional consequences of the spinal muscular atrophy-linked mutations of the survival motor neuron protein; stem cell therapy for MND; and the novel treatment for SMA and ALS in the introductory chapter. This book contains selected peer-reviewed chapters written by international researchers. In this publication, the readers will find a compilation of state-of-the-art reviews about etiology, therapies, investigations, the molecular basis of disease progression and clinical manifestations, and the genetic familial ALS, as well as novel therapeutic modalities. We look forward with confidence and pride to the remarkable role that this book will play for a new vision and mission.
Download or read book Motor Neuron Disease written by and published by . This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Upper Motor Neurone Syndrome and Spasticity by : Michael P. Barnes
Download or read book Upper Motor Neurone Syndrome and Spasticity written by Michael P. Barnes and published by Cambridge University Press. This book was released on 2001-02 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a thorough, practical reference and guide for all health professionals involved in the management of spasticity.
Book Synopsis The Hospital Neurology Book by : Arash Salardini
Download or read book The Hospital Neurology Book written by Arash Salardini and published by McGraw Hill Professional. This book was released on 2016-04-22 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical, protocol-oriented guide to the practice of neurology in the hospital setting A Doody's Core Title for 2019! Hospital neurology is one of the fastest growing subspecialties within neurology. Running an efficient and effective neurohospitalist line is important to the financial success of hospitals and the physicians employed there. Many neurology patients also have internal medicine problems, and often it is a general hospitalist without neurology training who treat these patients. These physicians sorely need more information on neurology. Conversely, neurologists caring for these patients have only had one year of internal medicine training and require more guidance on medical problems. Given these realities, there is a need for a resource on hospital neurology. With The Hospital Neurology Book, Drs. Salardini and Biller have created a practical, concise, and useful work that guides both neurologists and internists in the areas in which their training is currently not sufficient for hospital practice. The Hospital Neurology Book features a highly readable format, providing information physicians can act upon, including recipes and protocols for patient care and question-based chapter headings that lead physicians to the exact issue they are dealing with in the moment. Each chapter (or chapter section as appropriate) opens with a case study, setting the stage in a highly practical manner, and ends with high yield summary points useful for consolidating learning.
Download or read book Neuroproteomics written by Oscar Alzate and published by CRC Press. This book was released on 2009-10-26 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg
Book Synopsis Palliative Care in Amyotrophic Lateral Sclerosis by : David Oliver
Download or read book Palliative Care in Amyotrophic Lateral Sclerosis written by David Oliver and published by OUP Oxford. This book was released on 2014-03-20 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amytrophic Lateral Sclerosis (ALS or motor neurone disease) is a progressive neurodegenerative disease that can cause profound suffering for both the patient and their family. Whilst new treatments for ALS are being developed, these are not curative and offer only the potential to slow its progression. Palliative care must therefore be integral to the clinical approach to the disease. Palliative Care in Amyotrophic Lateral Sclerosis: From diagnosis to bereavement reflects the wide scope of this care; it must cover not just the terminal phase, but support the patient and their family from the onset of the disease. Both the multidisciplinary palliative care team and the neurology team are essential in providing a high standard of care and allowing quality of life (both patient and carer) to be maintained. Clear guidelines are provided to address care throughout the disease process. Control of symptoms is covered alongside the psychosocial care of patients and their families. Case studies are used to emphasise the complexity of the care needs and involvement of the patient and family, culminating in discussion of bereavement. Different models of care are explored, and this new edition utilizes the increase in both the evidence-base and available literature on the subject. New topics discussed include complementary therapies, personal and family experiences of ALS, new genetics research, and updated guidelines for patient care, to ensure this new edition remains the essential guide to palliative care in ALS.
Book Synopsis Introduction to Neural Engineering for Motor Rehabilitation by : Dario Farina
Download or read book Introduction to Neural Engineering for Motor Rehabilitation written by Dario Farina and published by John Wiley & Sons. This book was released on 2013-05-21 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural engineering is a discipline that uses engineering techniques to understand, repair, replace, enhance, or treat diseases of neural systems. Currently, no book other than this one covers this broad range of topics within motor rehabilitation technology. With a focus on cutting edge technology, it describes state-of-the-art methods within this field, from brain-computer interfaces to spinal and cortical plasticity. Touching on electrode design, signal processing, the neurophysiology of movement, robotics, and much more, this innovative volume collects the latest information for a wide range of readers working in biomedical engineering.
Book Synopsis Neurodegeneration by : Dennis Dickson
Download or read book Neurodegeneration written by Dennis Dickson and published by John Wiley & Sons. This book was released on 2011-09-09 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology. In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries. Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within cells (e.g. tau, α-synuclein and TDP-43) and in the extracellular compartments (e.g. β-amyloid and prion proteins) or according to a shared pathogenetic mechanism, such as trinucleotide repeats, that are a feature of specific genetic disorders. Chapters throughout the book conform to a standard lay-out for ease of access by the reader and are written by a panel of International Experts Since the first edition of this book, major advances have been made in the discovery of common molecular mechanisms between many neurodegenerative diseases most notably in the frontotemporal lobar degenerations (FTLD) and motor neuron disease or amyotrophic lateral sclerosis. This book will be essential reading for clinicians, neuropathologists and basic neuroscientists who require the firm up-to-date knowledge of mechanisms, diagnostic pathology and genetics of Neurodegenerative diseases that is required for progress in therapy and management.
Book Synopsis The Management of Motor Neurone Disease by : George M. Cochrane
Download or read book The Management of Motor Neurone Disease written by George M. Cochrane and published by . This book was released on 1987 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Anatomy and Physiology by : J. Gordon Betts
Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neurologic Differential Diagnosis by : Alan B. Ettinger
Download or read book Neurologic Differential Diagnosis written by Alan B. Ettinger and published by Cambridge University Press. This book was released on 2014-04-17 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unique case-based guide to generating diagnostic possibilities based on the patients' symptoms. Invaluable for psychiatrists and neurologists.
Book Synopsis Living with Motor Neurone Disease by : Marie Murray Marie
Download or read book Living with Motor Neurone Disease written by Marie Murray Marie and published by Atrium. This book was released on 2021-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Living with Motor Neurone Disease: A complete guide is designed to guide the reader through this complex progressive neurological condition that attacks the motor neurones, or nerves, in the brain and spinal cord. This means that messages gradually stop reaching the muscles, which leads to weakness and wasting. Motor Neurone Disease can affect the everyday things that we take for granted. A diagnosis of MND can be frightening and overwhelming. Good quality information and support from people who understand MND is vital at this time. Living with Motor Neurone Disease is written by many of the most distinguished Irish experts on MND, bringing safe, reliable, practical information and reassurance to everyone affected by Motor Neurone Disease. Having accurate information and timely access to the best available services including doctors, neurologists, MND outreach nurses and local community healthcare professionals makes all the difference when it comes to a person's journey with MND. This is a step-by-step guide for everyone which explains what MND is; how it is diagnosed; how it affects the individual and the family; the psychological dimensions of the condition; the caregiver experience; living with the condition and facing the future; how to talk to children and adolescents; how to tell family and friends; how to adapt working conditions and home life; and it describes all the supports; medical, psychological technological and practical to cope with the daily impact of living with MND. In summary, it is an invaluable resource to inform, educate prepare and signpost people toward practical everyday supports and clinical expertise. Living with Motor Neurone Disease: A complete guide is a must-read for professionals; for doctors, nurses, educationalists, for psychologists, systemic family therapists and psychotherapists, those working in human resources and everyone who needs to understand the condition when they encounter it.
Book Synopsis Motor Neuron Disease in Adults by : M. B. Bromberg
Download or read book Motor Neuron Disease in Adults written by M. B. Bromberg and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Motor Neuron Disease in Adults' reviews new information from 1998 as it applies to all aspects of motor neuron disease. Articles included use evidence-based methods to ensure that the new information is solid and advances the topic. The book can be used by anyone who provides any type of care to ALS patients.
